Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses by Fanping Wang, Yanhua Li, Can Yang, Yonghui Mu, Yan Wang, Wei Zhang, Yonghui Yang, Chen Chen, Shijun Song, Zhifa Shen, Wenjun Wang, Junpeng Li, Jingjing Zhai, Kang Guo, Ruili Sun, Lili Yu, Mingyong Wang

“…Finally, our data showed that PGN-mediated immune responses were more severely suppressed by preincubation with MBL and indicated that MBL can combine with both TLR2 and PGN to block the inflammation cytokine expression induced by PGN. All these data suggest that MBL could downregulate inflammation by modulating PGN/TLR2 signaling pathways. …”
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Analysis of central retinal microcirculation in glaucoma after neuroretinoprotective treatment by N.G. Glazko, A.E. Egorov

“…Before starting treatment and during the study, all patients underwent eye exams, i.e., visual acuity measurement, autorefractometry, slit lamp exam, eye fundus exam, IOP measurement, questioning to assess subjective vision, static automated perimetry, and optical coherence tomography angiography (OCTA) to evaluate foveal avascular zone / FAZ (area, perimeter, and circularity index). …”
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Structural Vulnerability Factors and Gestational Weight Gain:  A Scoping Review on the Extent, Range, and Nature of the Literature by Labonté, Jocelyne M, Dumas, Alex, Clark, Emily, Savard, Claudia, Fournier, Karine, O’Connor, Sarah, Morisset, Anne-Sophie, Fontaine-Bisson, Bénédicte

“…Methods: Electronic searches were performed in October 2018 (updated in August 2019) in MEDLINE(R) ALL, EMBASE, PsycINFO, CINAHL, and Sociological Abstracts databases. …”
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Temperament Upregulates Mitochondrial Enzymes and Negatively Affects Myofibrillar Fragmentation in Beef of Excitable <i>Bos taurus indicus</i> Cattle by Patricia Maloso Ramos, Eduardo Francisquine Delgado, Ana Cláudia da Silva, Nara Regina Brandão Cônsolo, Vinicius Laerte Silva Herreira, João Marcos Bovetto de Campos Valim, Fernanda Maria Marins Ocampos, Luiz Alberto Colnago, Saulo da Luz e Silva

“…Results: The pH decline was affected by all three fixed effects investigated (temperament × muscle × time post-mortem: <i>p</i> = 0.016), while temperature decline was affected by muscle × time (<i>p</i> < 0.001). …”
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Multicentre, multitime, multidimension, prospective follow-up cohort study on patients during the first wave of COVID-19 in China: a study protocol by Ming Zhang, Xuan Niu, Tonghui Liu, Chao Zheng, Huijie Yuan, Yanan Zhu, Huiping Liu, Shan Wu, Zhaoyao Luo, Jia Zhu, Danwei Hou, Tianhua Wei, Zhimin Zhu, Weipeng Huang, Weixian Bai, Xinyi Yu, Wenrui Bao

“…At the first time point, 501 participants (418 patients and 83 HCs) from nine recruiting hospitals have been observed. Ultimately, all of these results will be analysed to explore the short-term and long-term effects of COVID-19.Ethics and dissemination Ethics approval was granted by Ethics Committee of the First Affiliated Hospital of Xi'an Jiaotong University (XJTU1AF2023LSK-013). …”
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An Overview of the Environmental Applicability of Vermicompost: From Wastewater Treatment to the Development of Sensitive Analytical Methods by Madson de Godoi Pereira, Lourdes Cardoso de Souza Neta, Maurício Paulo Ferreira Fontes, Adriana Nascimento Souza, Thaionara Carvalho Matos, Raquel de Lima Sachdev, Arnaud Victor dos Santos, Marluce Oliveira da Guarda Souza, Marta Valéria Almeida Santana de Andrade, Gabriela Marinho Maciel Paulo, Joselito Nardy Ribeiro, Araceli Verónica Flores Nardy Ribeiro

“…The main advantages of vermicompost, considering all applications covered in this paper, comprise (i) easy acquisition, (ii) low costs, (iii) structural, chemical, and biological characteristics responsible for exceptional adsorptive capacities as well as pollutant degradation, and (iv) the promotion of biocontrol. …”
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Genomic detection of Panton-Valentine Leucocidins encoding genes, virulence factors and distribution of antiseptic resistance determinants among Methicillin-resistant S. aureus iso... by Masoud A. Juma, Tolbert Sonda, Boaz Wadugu, Davis Kuchaka, Mariana Shayo, Petro Paulo, Patrick Kimu, Livin E. Kanje, Melkiory Beti, Marco Van Zwetselaar, Blandina Mmbaga, Happiness Kumburu

“…The majority (82%) of the MRSA isolates bearing pvl genes were also found to exhibit the antiseptic/disinfectant genes in their genome. Moreover, all (80) sequenced MRSA isolates were found to harbor SCCmec type IV subtype 2B&5. …”
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Narratives of swiss football players about talent - and positive youth development: The role of social agents and agency. by Philipp Koch, Bryan Charbonnet, Noora Ronkainen

“…Central to this framework is the shift from static, one-size-fits-all approaches to a dynamic, idiographic perspective where intertwined relationships between athletes and their social environments influence each other over time. …”
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Short-term association between ambient air pollution and childhood non-allergic rhinitis: A time-series study at a National Children's Regional Medical Center, in Hefei, China, fro... by Wei Cui, Hongxia Gao, Liran Zhu, Yuanyuan Xu, Haipeng Liu

“…Lastly, boys and school children were found to be more vulnerable to air pollutants than girls and preschool children. All these findings suggest that air pollutants have adverse effects on childhood NAR, even at levels below those recommended by the air quality guidelines. …”
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Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood Transfusion by Rejane Santos Sousa, Antonio Humberto Hamad Minervino, Carolina Akiko Sato Cabral Araújo, Frederico Augusto Mazzocca Lopes Rodrigues, Francisco Leonardo Costa Oliveira, Clara Satsuki Mori, Janaina Larissa Rodrigues Zaminhan, Thiago Rocha Moreira, Isadora Karolina Freitas Sousa, Enrico Lippi Ortolani, Raimundo Alves Barrêto Júnior

“…Clinical observations were recorded throughout the transfusion, whereas heart rate, respiratory rate, and rectal temperature were assessed at the following times: 24 hours after phlebotomy and before transfusion; 30 minutes, six, twelve, 24, 48, 72, and 96 hours and eight and 16 days after transfusion. All groups presented transfusion reactions, among which hyperthermia was the most frequent (50% of animals). …”
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Inferior vena cava ultrasound in acute decompensated heart failure: design rationale of the CAVA‐ADHF‐DZHK10 trial by Alexander Jobs, Reinhard Vonthein, Inke R. König, Jane Schäfer, Matthias Nauck, Svenja Haag, Carlo Federico Fichera, Thomas Stiermaier, Jakob Ledwoch, Alisa Schneider, Miroslava Valentova, Stephan vonHaehling, Stefan Störk, Dirk Westermann, Tobias Lenz, Natalie Arnold, Frank Edelmann, Philipp Seppelt, Stephan Felix, Matthias Lutz, Felix Hedwig, Martin Borggrefe, Clemens Scherer, Steffen Desch, Holger Thiele

“…IVC ultrasound will be performed daily between baseline and hospital discharge in all patients. However, ultrasound results will only be reported to treating physicians in the intervention group. …”
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Dynamics of epidemiological indicators of glaucoma in the Republic of Bashkortostan for the period of 2010–2016 by M.M. Bikbov, A.E. Babushkin, I.I. Khusnitdinov, L. Kh. Murova, E.N. Matyukhina

“…The absolute number of people with primary disabilities with glaucoma was reduced due to high coverage of the population with annual preventive examinations with an increasing number of identified patients suspected of having this disease (6304 vs. 7685) and its primary detection at the initial stages, an increase of antiglaucoma operations (including those performed using drains and non-penetrating technology), a broader purpose and use of modern and effective anti-hypertensive drops, first of all, prostaglandins (2 times) and fixed combinations (1.5 times). …”
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Prediction of Pathologic Response in Unresectable Hepatocellular Carcinoma After Downstaging with Locoregional and Systemic Combination Therapy by Yang C, Chen Y, Sheng L, Wang Y, Zhang X, Yang Y, Ronot M, Jiang H, Song B

“…Performance of the response criteria in predicting pathologic response was assessed with the area under the receiver operator characteristic curve (AUC).Results: Among all radiologic and pathologic response criteria, MPR was the only independent predictor of post-resection recurrence-free survival (RFS) (adjusted hazard ratio 0.34, 95% CI 0.16– 0.72, p=0.004). …”
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Comparison of the effects of 3 kinds of oils rich in omega-3 polyunsaturated fatty acids on glycolipid metabolism and lipoprotein subfractions by Hechun Liu, Feng Wang, Hui Xia, Da Pan, Ligang Yang, Shaokang Wang, Feng Zhao, Guiju Sun

“…There was a significant reduction of glycated hemoglobin (HbA1c) in all the groups. The triglycerides (TG) in the FO group were significantly different with a group × time interaction (P = 0.043), which was higher compared with the other two groups. …”
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Realization of a cascade treatment algorithm for glaucoma in St. Petersburg by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy

“…., three agents in two bottles). Simultaneous use of all four major classes of IOP-lowering medications occurred in 10% of patients only. …”
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Club Cell Protein 16 Attenuates CD16brightCD62dim Immunosuppressive Neutrophils in Damaged Tissue upon Posttraumatic Sepsis-Induced Lung Injury by Nils Becker, Philipp Störmann, Andrea Janicova, Kernt Köhler, Klemens Horst, Ildiko Rita Dunay, Claudia Neunaber, Ingo Marzi, Jan Tilmann Vollrath, Borna Relja

“…Results from untreated ctrl and IgG-treated mice were statistically comparable between all corresponding sham, TxT, and TxT+CLP groups. …”
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Evaluation of Medical Care for Diabetic and Hypertensive Patients in Primary Care in Mexico: Observational Retrospective Study by Agustin Lara-Esqueda, Sergio A. Zaizar-Fregoso, Violeta M. Madrigal-Perez, Mario Ramirez-Flores, Daniel A. Montes-Galindo, Margarita L. Martinez-Fierro, Iram P. Rodriguez-Sanchez, José Guzman-Esquivel, Carmen Meza-Robles, Gabriel Ceja-Espiritu, Pablo A. Kuri-Morales, Josuel Delgado-Enciso, Armando Barriguete-Melendez, Hector R. Galvan-Salazar, Carlos E. Barajas-Saucedo, Elvin Guillermo-Espinosa, Agustin D. Lara-Basulto, Jesus F. Gonzalez-Roldan, Ivan Delgado-Enciso

“…Methods. 45,498 patients were included from 2012 to 2015. All information was taken from the electronic medical record database. …”
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Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2... by Claudia Volecker-Rehage, Uros Marusic, Bettina Wollesen, Antoine Langeard, Tamar Yellon, Anna Wunderlich, Vera Belkin, Guoping Qian, Eleftheria Giannouli, Zbigniew Ossowski, Rafael A. Bernades, Yael Netz, Rajesh Sighdel

“…Therefore, after identifying all potential interventions, we will use the F.I.T.T. principles (frequency, intensity, time, type) as well as the physical and health status of the participants as moderators to analyse the mechanisms for the positive benefits of exercise interventions. …”
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Synergistic thermal and surface area properties of Al2O3–TiO2/water hybrid nanofluids by Yokanan Gustino Djentoe, Farrel Yoga Widiasto, Hilbran Tama Dida Effendi, Musabbikhah, Sri Hartati, Budi Santoso, Budi Kristiawan, Agung Tri Wijayanta

“…Heat capacity increases significantly from 4 to 8 MJ/m2·K, with the fastest change occurring between 20 and 30 °C, whereas thermal diffusivity is bounded between 0 and 0.2 mm2/s. All of this highlights the potential applications in analysis and energy storage, highlighting the transfer characteristics of nanomaterials that are useful. …”
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Longitudinal impact of cross-clamp duration on postoperative sleep disturbance and quality of life in elderly cardiac surgery patients: a secondary analysis of the MINDDS trial by Grace E. Namirembe, Jamie Sparling, Alexis Novak, Ariel Mueller, Julia Bertsch, Kwame Wiredu, Jason Z. Qu, M. Brandon Westover, Timothy T. Houle, Oluwaseun Akeju

“…However, isolated CABG patients reported sleep disturbance at all time points. Notably, extended cross-clamp time (&gt;90 min) significantly worsened the trajectories of mental health (90-day: MD −2.37 points, 95% CI: −4.35, −0.39; 180-day: MD −2.68 points, 95% CI: −4.62, −0.73) and applied cognition (180-day: MD: −2.59 points, 95% CI: −4.49, −0.68).ConclusionRegardless of the duration of the cross-clamp, sleep quality tends to improve over time following cardiac surgery. …”
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