Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis by Bruley, Apolline, Gaëtan, Juliette, Gugger, Muriel, Pancrace, Claire, Millet, Maxime, Gaschignard, Geoffroy, Dezi, Manuela, Humbert, Jean-François, Leloup, Julie, Skouri-Panet, Fériel, Callebaut, Isabelle, Benzerara, Karim, Duprat, Elodie

“…This suggests that they all could be part of an operon, and may play a concerted role in iACC formation. …”
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Thermodynamic and experimental evaluation of the sustainable recycling of magnesium alloy scrap by vacuum distillation based on vapor-liquid equilibrium by Lipeng Wang, Dong Liang, Yang Tian, Jianxue Chai, Rui Li, Shuji Wu, Bin Yang, Baoqiang Xu, Yong Deng

“…Thermodynamic analyses and experimental results showed that inclusions and impurity metals of separation coefficient lgβi ≤ -5, including Cu, Fe, Co, and Ni below 0.001 ppm, could be removed from the matrix. All Zn entered the recycled Mg, while impurities with -1 < lgβi < -5 such as Li, Ca, and Mn severely affected the purity of the recycled Mg during the later stage of distillation. …”
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Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Li... by Di Jin, Kai Kang, Bing-zhu Yan, Jian-nan Zhang, Jun-bo Zheng, Zhi-hui Wang, Di Wu, Yu-jia Tang, Xin-tong Wang, Qi-qi Lai, Yang Cao, Hong-liang Wang, Yang Gao

“…A total of 73 adult patients with ALF undergoing 204 PE were included in our retrospective study, and their transplant-free mortality at discharge and 90 days was 6.85% (5/73) and 31.51% (23/73), respectively. All deaths could be attributed to ALF-induced severe and life-threatening complications or even multiple organ dysfunction syndrome (MODS). …”
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Gut microbiota drives colon cancer risk associated with diet: a comparative analysis of meat-based and pesco-vegetarian diets by Carlotta De Filippo, Sofia Chioccioli, Niccolò Meriggi, Antonio Dario Troise, Francesco Vitali, Mariela Mejia Monroy, Serdar Özsezen, Katia Tortora, Aurélie Balvay, Claire Maudet, Nathalie Naud, Edwin Fouché, Charline Buisson, Jacques Dupuy, Valérie Bézirard, Sylvie Chevolleau, Valérie Tondereau, Vassilia Theodorou, Claire Maslo, Perrine Aubry, Camille Etienne, Lisa Giovannelli, Vincenzo Longo, Andrea Scaloni, Duccio Cavalieri, Jildau Bouwman, Fabrice Pierre, Philippe Gérard, Françoise Guéraud, Giovanna Caderni

“…PVD determines a selection of nine taxonomic markers mainly belonging to Lachnospiraceae and Prevotellaceae families exclusively associated with at least two different animal models, and within these, four taxonomic markers were shared across all the three animal models. An inverse correlation between nonconjugated bile acids and bacterial genera mainly belonging to the Lachnospiraceae and Prevotellaceae families (representative of the PVD group) was present, suggesting a potential mechanism of action for the protective effect of these genera against CRC. …”
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Impacto del seguimiento al alta de Enfermería en Atención Primaria sobre los reingresos hospitalarios tempranos. Estudio observacional longitudinal by Raquel Sánchez-Ruano, Pedro López-Paterna, César Alfonso García-Hernández, Ricardo Rodríguez-Barrientos, Elvira Herrero-Sanchox, Marcos Pascual-García, Milagros Rico-Blázquez

“…According to the logistic regression model performed between early readmission and discharge follow-up, adjusted for all other factors, the group with discharge follow-up had a 66% lower likelihood of hospital readmission (OR 0.34, 95% CI (0.18-0.67)). …”
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Revealing the biological features of the axolotl pancreas as a new research model by Hui Ma, Hui Ma, Hui Ma, Guangcong Peng, Yan Hu, Binbin Lu, Binbin Lu, Yiying Zheng, Yingxian Wu, Weimin Feng, Yu Shi, Xiangyu Pan, Li Song, Ina Stützer, Yanmei Liu, Jifeng Fei, Jifeng Fei, Jifeng Fei

“…To assess pancreatic gene function, Pdx1 mutants were generated using CRISPR/Cas9-mediated gene editing, and their effects on pancreatic morphology, endocrine cell populations, and glucose homeostasis were analyzed.ResultsThe axolotl pancreas contains all known pancreatic cell types and develops from dorsal and ventral buds. …”
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Twenty years’ experience of midgut malrotation and volvulus in a tertiary center in northern Taiwan: A retrospective study by Wen-Yu Tseng, Ming-Wei Lai, Jin-Yao Lai, Chien-Chang Chen, Hsun-Chin Chao, Jeng-Chang Chen, Shih-Yen Chen, Yung-Ching Ming, Hung-Yu Yeh, Hung-Hsiang Lai, Sze-Ya Ting, Pai-Jui Yeh

“…Patients were classified into the poor-outcome group (PO) if they underwent bowel resection or experienced mortality; all others were categorized as the favorable-outcome group (FO). …”
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Association of blood group types and clinico-pathological features of gynecological cancers (GCs) by Syed Sameer Aga, Muhammad Anwar Khan, Mubarak Al Mansour, Rana Mohammed Hasosah, Lulu Abdullah Alsubaie, Dala Ahmad Alfaify, Malak Badr Alansari, Shahad Obaidallah Almutairi, Saniya Nissar

“…Methods The current retrospective cross-sectional study was carried out between the years of 2016 and 2023. The sample included all the patients having age > 18 with a record of blood group and confirmed histological or cytological diagnosis as per International Federation of Gynecology and Obstetrics (FIGO) guidelines. …”
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Editorial by Jörg Tremmel, Edward Page, Konrad Ott

“…An additional argument is that all of the main greenhouse gases remain in the atmosphere for many decades after release. …”
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Sex disparity in the association between alcohol consumption and sarcopenia: a population-based study by Longbao Yang, Longbao Yang, Qiuju Ran, Qiuju Ran, Yee Hui Yeo, Zhang Wen, Zhang Wen, Shuyue Tuo, Shuyue Tuo, Yong Li, Yong Li, Jia Yuan, Jia Yuan, Shejiao Dai, Shejiao Dai, Jinhai Wang, Jinhai Wang, Fanpu Ji, Fanpu Ji, Fanpu Ji, Fanpu Ji, Xinxing Tantai, Xinxing Tantai

“…Stratified analyses revealed that these associations were present in females but not males.ConclusionAlcohol intake was associated with an increased risk of sarcopenia in all individuals, with this association being primarily observed in females rather than males.…”
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DMMR status and synchronous lesions predicts metachronous lesions after curative resection for rectal cancer by Xijie Chen, Xijie Chen, Xijie Chen, Junguo Chen, Junguo Chen, Junguo Chen, Liang Xu, Liang Xu, Dezheng Lin, Dezheng Lin, Dezheng Lin, Xiaoling Hong, Xiaoling Hong, Xiaoling Hong, Junsheng Peng, Junsheng Peng, Junsheng Peng, Xiaowen He, Xiaowen He, Xiaowen He, Jiancong Hu, Jiancong Hu, Jiancong Hu

“…Clinicopathological variables were analyzed by logistic regression analysis to identify risk factors independently associated with metachronous neoplasms in patients that underwent curative rectal cancer surgery.ResultsIn all, 554 patients were included in the analysis. …”
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Ovarian stimulation alternatives for in vitro production of embryos in water buffaloes by Alexis Bandeo, José Luis Konrad, Natalia Vallejos, Pablo Ponce, Marina J. Sansinena, Gustavo Crudeli, Pablo Maldonado-Vargas

“…In vitro culture (IVC) was carried out for 6.5 days, and all embryos that reached the blastocyst stage were graded and vitrified. …”
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Molecular assessment of splicing variants in a cohort of patients with inborn errors of immunity: methodological approach and interpretation remarks by Laura Miguel Berenguel, Carla Gianelli, Carla Gianelli, Carla Gianelli, Elisabet Matas Pérez, Teresa del Rosal, Ana Méndez Echevarría, Ángel Robles Marhuenda, Marta Feito Rodríguez, Maria Teresa Caballero Molina, Maria Teresa Caballero Molina, Lorena Magallares García, Brenda Sánchez Garrido, Samantha Hita Díaz, Luis Allende Martínez, Luis Allende Martínez, Pilar Nozal Aranda, Pilar Nozal Aranda, Pilar Nozal Aranda, Carmen Cámara Hijón, Carmen Cámara Hijón, Carmen Cámara Hijón, Eduardo López Granados, Eduardo López Granados, Eduardo López Granados, Rebeca Rodríguez Pena, Rebeca Rodríguez Pena, Rebeca Rodríguez Pena, María Bravo García-Morato, María Bravo García-Morato, María Bravo García-Morato

“…Seven patients showed variants outside canonical positions. All of them needed molecular validation, with the exception of two patients, whose variants had previously been well characterized in the medical literature.ConclusionThis study shows the proportion of splicing variants in a cohort of IEI patients, providing their clinical phenotypic characteristics and the methodology used to validate the splicing defects. …”
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Sacubitril/Valsartan for Blood Pressure Lowering in Non‐Dialysis‐Dependent Chronic Kidney Disease Stage 3–5 Patients With Hypertension: A Multicenter Clinical Study by Yu Yan, Xiaomin Li, Juan Cao, Jingyuan Cao, Yao Wang, Liang Wang, Jirong Yu, Lianhua Chen, Min Yang, Xinzhong Huang, Lei Shen, Hong Ding, Manzhi Li, Di Yin, Linglin Jiang, Liang Tang, Yujia Jiang, Ling Hu, Jiyi Si, Hui Zhang, Liqin Cui, Xiameng Gu, Kun Hu, Dongxing Mu, Bicheng Liu, Xiaoliang Zhang, Dong Sun, Xin Wan, Bin Wang

“…At the study endpoint, mean systolic blood pressure, diastolic blood pressure, and pulse pressure were markedly reduced compared to baseline (all p < 0.001). The average blood pressure reductions were 12.17 (4.66, 22.00), 6.00 (0.67, 12.66), and 6.67 (0.08, 14.00) mmHg, respectively. …”
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Selection of suitable reference lncRNAs for gene expression analysis in Osmanthus fragrans under abiotic stresses, hormone treatments, and metal ion treatments by Yingting Zhang, Yingting Zhang, Qingyu Yan, Hui Xia, Xiangling Zeng, Xiangling Zeng, Xiangling Zeng, Jie Yang, Jie Yang, Jie Yang, Xuan Cai, Xuan Cai, Xuan Cai, Zeqing Li, Zeqing Li, Hongguo Chen, Hongguo Chen, Hongguo Chen, Jingjing Zou, Jingjing Zou, Jingjing Zou

“…., delta-Ct, NormFinder, geNorm, BestKeeper, and RefFinder, to evaluate the expression stability of 17 candidate RGs across various experimental conditions.Results and discussionThe results indicated the most stable RG combinations under different conditions as follows: cold stress: lnc00249739 and lnc00042194; drought stress: lnc00042194 and lnc00174850; salt stress: lnc00239991 and lnc00042194; abiotic stress: lnc00239991, lnc00042194, lnc00067193, and lnc00265419; ABA treatment: lnc00239991 and 18S; MeJA treatment: lnc00265419 and lnc00249739; ethephon treatment: lnc00229717 and lnc00044331; hormone treatments: lnc00265419 and lnc00239991; Al3+ treatment: lnc00087780 and lnc00265419; Cu2+ treatment: lnc00067193 and 18S; Fe2+ treatment: lnc00229717 and ACT7; metal ion treatment: lnc00239991 and lnc00067193; flowering stage: lnc00229717 and RAN1; different tissues: lnc00239991, lnc00042194, lnc00067193, TUA5, UBQ4, and RAN1; and across all samples: lnc00239991, lnc00042194, lnc00265419 and UBQ4. …”
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Minute-cadence Observations of the LAMOST Fields with the TMTS. VI. Physical Parameters of Contact Binaries by Qiqi Xia, Xiaofeng Wang, Kai Li, Xiang Gao, Fangzhou Guo, Jie Lin, Cheng Liu, Jun Mo, Haowei Peng, Qichun Liu, Gaobo Xi, Shengyu Yan, Xiaojun Jiang, Jicheng Zhang, Cui-Ying Song, Jianrong Shi, Xiaoran Ma, Danfeng Xiang, Wenxiong Li

“…The absolute physical parameters were inferred with the W-D code for 10 systems, all of them are W-type shallow or medium contact binaries. …”
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Several factors that predict the outcome of large B‐cell lymphoma patients who relapse/progress after chimeric antigen receptor (CAR) T‐cell therapy can be identified before cell a... by Alice Sýkorová, František Folber, Kamila Polgárová, Heidi Móciková, Juraj Ďuraš, Kateřina Steinerová, Aleš Obr, Adriana Heindorfer, Miriam Ladická, Ľubica Lukáčová, Erika Čellárová, Ivana Plameňová, David Belada, Andrea Janíková, Marek Trněný, Tereza Jančárková, Vít Procházka, Andrej Vranovský, Margaréta Králiková, Jan Vydra, Lukáš Smolej, Ľuboš Drgoňa, Martin Sedmina, Eva Čermáková, Robert Pytlík

“…The risk factors for a shorter PFS‐2 (n = 39) included: CRP > limit of the normal range (LNR) before LD, albumin < LNR and ECOG PS > 1 at R/P. All these factors, together with LDH > LNR before LD and EN involvement at R/P, predicted OS‐2 for treated patients. …”
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Immune and genomic biomarkers of immunotherapy response in cancer of unknown primary by Madhu Singh, Linda Mileshkin, Penelope Schofield, Bo Gao, Gary Richardson, Andrew Pattison, Rodney J Hicks, Niko Thio, Mark Warren, Colin Wood, Stephen B Fox, Anna DeFazio, Andrew Fellowes, Christopher Steer, David Bowtell, Nicholas Wilcken, Tharani Sivakumaran, Atara Posner, Dariush Etemadmoghadam, Krista Fisher, Samantha Webb, Christos S Karapetis, Ian M Collins, Narayan Karanth, Owen W J Prall, Richard William Tothill

“…Among non-responders, 9 had stable and 11 had progressive disease. All responders had a high IR score (7/8) and/or high TMB (3/8), while most (5/8) belonged to ICI-responsive cancer types. …”
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Phase II, single-arm trial of preoperative short-course radiotherapy followed by chemotherapy and camrelizumab in locally advanced rectal cancer by Jun Fan, Jing Wang, Tao Zhang, Xin Li, Lan Zhang, Zheng Wang, Tao Liu, Gang Li, Peng Zhang, Chi Ma, Ming Cai, Gang Wu, Zhenyu Lin, Kailin Cai, Xiu Nie, Junli Liu, Hongli Liu, Weikang Zhang, Jingbo Gao, Chuanqing Wu, Linfang Wang, Zhiguo Hou, Kunyu Yang, Kaixiong Tao

“…Immune-related adverse events were all grade 1–2, with the most common being reactive cutaneous capillary endothelial proliferation (81.5%). …”
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Functionally important respiratory symptoms and continued cigarette use versus e-cigarette switching: population assessment of tobacco and health study waves 2-6Research in context by James D. Sargent, Kristin Lauten, Kathryn C. Edwards, Susanne E. Tanski, Todd A. MacKenzie, Laura M. Paulin, Mary F. Brunette, Maciej L. Goniewicz, Amanda Malasky, Debra Stark, Fernando B. de Moura, Holly Griffin, Kimberly H. Nguyen, Eric Backlund, Heather L. Kimmel, John H. Kingsbury, Jenny E. Ozga, K Michael Cummings, Andrew Hyland

“…Findings: Among those with an index score <2, 3.5% switched to e-cigarettes, and 11.1% quit all tobacco. Functionally important respiratory symptoms worsened (≥2 at follow-up) in 15.4%, 10.0% and 10.1% of those who continued cigarettes, switched to e-cigarettes, and quit, respectively. …”
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