Upadacitinib in active non-radiographic axial spondyloarthritis: 2-year data from the phase 3 SELECT-AXIS 2 study by Filip Van den Bosch, Atul Deodhar, Denis Poddubnyy, Walter P. Maksymowych, Désirée van der Heijde, Tae-Hwan Kim, Mitsumasa Kishimoto, Xenofon Baraliakos, Xianwei Bu, Ivan Lagunes-Galindo, In-Ho Song, Peter Wung, Koji Kato, Anna Shmagel

“…Patients were randomized 1:1 to receive double-blinded treatment with upadacitinib 15 mg once daily (QD) or placebo for 52 weeks, after which all patients received open-label treatment with upadacitinib 15 mg QD. …”
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Baricitinib treatment for hospitalized patients with severe COVID-19 on invasive mechanical ventilation: a propensity score-matched and retrospective analysis by Yanxiong Mao, Anyi Guo, Ying Zhang, Jianxing Lai, Dian Yuan, Hao Zhang, Wenqi Diao, Weisong Chen, Fugui Yan

“…Baricitinib group had significantly lower all-cause 28-days mortality than control group (72.9% vs. 89.6%, p = 0.004).ConclusionThe present study revealed baricitinib reduced 28-days mortality in severe COVID-19 patients on IMV. …”
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Diagnostic Accuracy of Serum Prostate Specific Antigen and Gleason Score in Determining the Presence of Skeletal Metastasis in Prostate Cancer Patients: a Pakistani Perspective by Taimoor Nasir, Syeda Neha Aamer, Saman Waqar, Wafa Omer

“…If these results are applied in hospitals all over the country, we can significantly reduce the burden on our resources and prevent unnecessary, low-yield diagnostic tests from being carried out.     …”
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Combining UAS LiDAR, Sonar, and Radar Altimetry for River Hydraulic Characterization by Monica Coppo Frias, Alexander Rietz Vesterhauge, Daniel Haugård Olesen, Filippo Bandini, Henrik Grosen, Sune Yde Nielsen, Peter Bauer-Gottwein

“…UAS hydrometry can provide WSE, WSS, water surface velocity and riverbed geometry at a high spatial resolution, making it suitable for rivers of all sizes. The use of UAS hydrometry can enhance river management, with cost-effective surveys offering large coverage and high-resolution data, which are fundamental in flood risk assessment, especially in areas that difficult to access. …”
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Linear association between high-sensitivity C-reactive protein and postoperative delirium after general anesthesia: a cross-sectional study by Xiao Qin, Junming Ren, Chunping Xing, Lijiao Chen, Renjie Wang, Shouyuan Tian

“…Multivariate logistic regression confirmed that elevated Hs-CRP and its forms (Log10Hs-CRP, standardized Hs-CRP, and higher Hs-CRP group) consistently increased the risk of POD across all adjusted models (p < 0.05). Stratified analyses further highlighted significant associations between Hs-CRP and POD in specific subgroups, notably in patients aged ≥65 years, female patients, and those with or without hypertension, diabetes, or stroke history, and without chronic kidney disease (p < 0.05). …”
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Management of Vasoproliferative Tumors of the Retina with Macular Complications by Pars Plana Vitrectomy Combined with Episcleral Cryotherapy by Wenhua Zhang, Zeyuan Qiang, Hao Song, Xiaoli Li, Handong Dan, Keke Ge, Pan Li, Zixu Huang, Dongdong Wang, Feng Chen, Bin Zheng, Zongming Song

“…In this retrospective noncomparative interventional case-series analysis, we included 11 eyes of ten patients diagnosed with VPTR. All patients underwent comprehensive ophthalmic examinations and were treated with PPV combined with episcleral cryotherapy. …”
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LEGAL AND ECONOMIC PRINCIPLES OF THE FOREIGN POLICY OF INDEPENDENT AZERBAIJAN IN RELATION TO NEIGHBORING COUNTRIES by Katana Gafarova

“…The relationship between the economic and legal components in the content of the country's foreign policy activity is differentiated, where the economy acts as a means and functionality for the use of a certain set of resources for the production, sale, distribution and consumption of public goods, and the law ensures the structuring of all social phenomena according to certain rules of behaviour in terms of satisfying public and private interests in the context of building a compromise model of the relationship between them. …”
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Estimating Trends in Cardiovascular Disease Risk for the EXPOSE (Explaining Population Trends in Cardiovascular Risk: A Comparative Analysis of Health Transitions in South Africa a... by Shaun Scholes, Jennifer S Mindell, Mari Toomse-Smith, Annibale Cois, Kafui Adjaye-Gbewonyo

“…The absolute predicted 10-year risk of CVD declined significantly on average over the last 2 decades in both sexes (for linear trend; all P<.001). In men, the mean of the laboratory-based WHO risk score was 10.1% (SE 0.2%) and 8.4% (SE 0.2%) in 1998 and 2017, respectively; corresponding figures in women were 5.6% (SE 0.1%) and 4.5% (SE 0.1%). …”
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Pre-CCRT 18-fluorodeoxyglucose PET-CT improves survival in patients with advanced stages p16-negative oropharyngeal squamous cell carcinoma via accurate radiation treatment plannin... by Tsung-Ming Chen, Wan-Ming Chen, Mingchih Chen, Ben-Chang Shia, Szu-Yuan Wu

“…The adjusted hazard ratio (95% confidence interval) of all-cause death for the patients with advanced stages (III–IVA) of p16-negative OPSCC receiving pre-CCRT 18FDG PET–CT was 0.75 (0.87–0.94, P = 0.0236). …”
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Preventive Effects of Intrauterine Injection of Bone Marrow-Derived Mesenchymal Stromal Cell-Conditioned Media on Uterine Fibrosis Immediately after Endometrial Curettage in Rabbit by Sanaz Bazoobandi, Nader Tanideh, Farhad Rahmanifar, Shahrokh Zare, Omid Koohi-Hosseinabadi, Iman Razeghian-Jahromi, Mehdi Dianatpour, Masoumeh Ahmadi, Arezoo Khoradmehr, Iraj Nabipour, Zahra Khodabandeh, Amin Tamadon

“…However, the amount of fibrotic tissue in the CM and the BM-MSC injection groups was the same as the normal control groups, and all were less than the curettage group. A single injection of CM of MSCs after 30 days prevented the fibrotic tissue formation induced by curettage in endometrial layers of rabbits. …”
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The prevalence of malaria in the five districts of Limpopo Province, South Africa, 2015 - 2017 by M T Lamola, A Musekiwa, A de Voux, C Reddy, M Morifi, P C Mutevedzi

“…During 2010 - 2014, SA reported that ~47.6% of all malaria cases were imported. Contemporary estimates for the prevalence of malaria in the five districts of Limpopo Province are limited, with unknown proportions of imported malaria cases. …”
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Risk factors and consequences of traumatic brain injury in a Swiss male population cohort by Jean-Bernard Daeppen, Gerhard Gmel, Joseph Studer, Valentin Petre Matei, Alina Elena Rosca, Alexandru Neculai Pavel, Radu Mihai Paun

“…Risk factors were measured at baseline (2010–2012) and at follow-up 1 (FU1; 2012–2014), while the consequences and TBI were measured at follow-up 2 (FU2; 2016–2018).Setting Switzerland.Participants All participants at FU2 (Mage=25.43, SD=1.25) of the Cohort Study on Substance Use Risk Factors (N=4881 young Swiss men after listwise deletion).Measures The outcomes measured were TBI, SUD (ie, alcohol, nicotine, cannabis, other illicit drugs), depression and personality traits (ie, sensation seeking, anxiety-neuroticism, sociability, aggression-hostility) at FU2. …”
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Significance of Heparin-Binding Protein and D-dimers in the Early Diagnosis of Spontaneous Bacterial Peritonitis by Tomasz Mikuła, Mariusz Sapuła, Joanna Jabłońska, Joanna Kozłowska, Wojciech Stańczak, Dagny Krankowska, Alicja Wiercińska-Drapało

“…Department of Infectious and Tropical Diseases and Hepatology, Medical University of Warsaw, Poland. Patients. All patients admitted to the aforementioned department with decompensated liver cirrhosis and ascites between February 1, 2016, and June 30, 2017. …”
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Insights Into Antimicrobial Resistance From Dental Students in the Asia–Pacific Region by Saba Ghafoor, Gabriela Salvadori, Shiho Kino, Vy Thi Nhat Nguyen, Tam Thi-Thanh Nguyen, Miho Ishimaru, Antônio Pedro Ricomini-Filho, Cassiano Kuchenbecker Rösing, Dileep De Silva, Jun Aida, Belinda Farias Nicolau, Ratilal Lalloo, Roger Junges

“…A previously validated and standardised 14-item instrument was utilised. Results: In all, 1413 responses were collected from Australia (n = 165), Sri Lanka (n = 112), Japan (n = 173), and Vietnam (n = 963). …”
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International prevalence of consultation with a naturopathic practitioner: a systematic review and meta-analysis by Amie Steel, Jon Adams, Brenda Leung, Holger Cramer, Matthew J Leach, Jon Wardle, Joshua Goldenberg, Janet Schloss, Rebecca Redmond, Joanna Elizabeth Harnett, Claudine Van de Venter, Andy McLintock, Ryan Bradley, Jason Hawrelak, Kieran Cooley

“…Other prevalence timeframes were reported as secondary measures.Methods Meta-analysis of prevalence data was conducted using random effects models based on individual countries and WHO world regions.Results The literature search identified eight manuscripts summarising 14 studies reporting prevalence for inclusion in the review. All included studies had a low risk of bias. Meta-analysis of the included studies by world region found the 12-month prevalence of history of naturopathy consultations ranged from 1% in the Region of the Americas to 6% in the European and Western Pacific Regions.Conclusions There are up to sixfold differences in the prevalence of naturopathy consults over 12 months between and within world regions, which may be driven by a range of policy, legislative and social factors.PROSPERO registration number CRD42020145529.…”
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Identification of QTL for Plant Height Traits in Single-segment Substitution Lines of Wild Rice by Xingxin DAI, Yanjie LIU, Chengxia LI, Rui TANG, Jiamei MU, Xuelin FU

“…【Results】The plant heights of the MER-SSSLs and BAR-SSSLs showed a unimodal distribution in all three seasons with a wide variation range, and the ranges were from 80.74 cm to 116.22 cm and 80.26 cm to 167.33 cm, respectively. …”
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Synthesizing Local Capacities, Multi-Source Remote Sensing and Meta-Learning to Optimize Forest Carbon Assessment in Data-Poor Regions by Kamaldeen Mohammed, Daniel Kpienbaareh, Jinfei Wang, David Goldblum, Isaac Luginaah, Esther Lupafya, Laifolo Dakishoni

“…Notably, a stacking ensemble of support vector machines and random forest achieved the highest accuracy (R² = 0.84, RMSE = 1.36), followed by an ensemble of all base learners (R² = 0.83, RMSE = 1.39). …”
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The Epidemiological Characteristics of Coronavirus Disease (COVID-19) in Halabja Province/Kurdistan –Iraq by Osama Hamid Shareef, Othman Abdulrahman Mohammed, Dashty Aziz Ghafor, Ari Shareef Ali, Hardi Rafat Baqi, Ali Aziz Ali, Aryan Mahmood Faraj, Syamand Ahmed Qadir, Ali Muhi Aldeen Omar Aljabary

“…During the study, 5183 cases were tested, 2796 (54%) cases were confirmed as positive result and 2387 (46%) cases were negative, including all ages, males and females. Confirmed male cases among 3116 cases were 1646 (60.1%), and 1150 (39.9%) positive cases recorded among 2067 female tests. …”
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Epidemiology of notifiable outbreaks in different hospital units in Saudi Arabia: A national descriptive study by Nawal M. Alanazi, Nasser H. Alshanbari, Hala M. Roushdy, Yahya I. Alnshbah, Eman Ali Barnawi, Nawaf M. Almatrafi, Rula Felemban, Zainah M. Al Shahrani, Nadeen Burhan, Aiman El-Saed, Khalid H. Alanazi

“…Males represented 62.3 % of the patients, and the average age was 51.2 ± 27.7 years. Almost all patients had devices: central line (63.6 %), foley catheters (52.7 %), or mechanical ventilation (50.4 %). …”
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Pengukuran Performa Apache Spark dengan Library H2O Menggunakan Benchmark Hibench Berbasis Cloud Computing by Aminudin Aminudin, Eko Budi Cahyono

“…The success can be seen from the test parameters that have been tested including the value of running time, throughput, Avarege Memory and CPU Average obtained from the Hibench Benchmark. All these values are influenced by the amount of data and number of nodes. …”
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