PCR-detection rates of T. pallidum ssp. pallidum in swab samples from the Czech Republic (2004–2022): Combined RPR, IgM, and PCR tests efficiently detect active syphilis by Eliška Vrbová, Petra Pospíšilová, Eliška Dastychová, Martina Kojanová, Miluše Kreidlová, Daniela Vaňousová, Filip Rob, Přemysl Procházka, Alena Krchňáková, Vladimír Vašků, Radim Strnadel, Olga Faustmannová, Monika Dvořáková Heroldová, Ivana Kuklová, Hana Zákoucká, David Šmajs

“…A combination of RPR + PCR, or a combination of all three tests (RPR, IgM, and PCR) can therefore be used to reliably detect active syphilis cases, including reinfections. …”
Get full text

Adequate Reporting Among Ventral Hernia Repair Operative Reports: A Cross-Sectional Study of Prevalence of Details and Association With Clinical Outcomes by Said Maldonado, BS, Nicole B. Lyons, MD, Jonathan S. Lall, BS, J. Scott Zimmerle, MBA, Brendan Rosamond, BS, Ashlynn Mills, BS, Yoolim Alex Seo, BS, Angelica Calderon Rodriguez, BS, Rainna Coelho, MD, Natalia Cavagnaro, MD, Zuhair Ali, MD, Mike K. Liang, MD

“…More recent operative reports, cases with resident involvement, and contaminated procedures were more likely to be highly detailed (all P < 0.05). Compared to poorly detailed operative reports, cases with highly detailed reports had fewer SSIs (13.2% vs 7.5%, P = 0.006), hernia recurrence (65.8% vs 55.4%, P = 0.002), and reoperation (78.9% vs 62.6%, P = 0.001). …”
Get full text

Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus by Saowanee Chamnanya, Benyapa Kiddela, Jassada Saingamsook, Woottichai Nachaiwieng, Nongkran Lumjuan, Pradya Somboon, Jintana Yanola

“…Results Bioassay tests revealed a significantly higher resistance level in Cq_SP-R than in Cq_NiH-R strains in both larvae and adults. All eight cytochrome P450 genes were significantly overexpressed in larvae of Cq_NiH-R strain compared to the parent and susceptible Cq_Sus strains. …”
Get full text

Implementasi Metode Longest Common Subsequences untuk Perbaikan Kata pada Kasus Analisis Sentimen Opini Pembelajaran Daring di Media Sosial Twitter by Alfisyar Jefry Pranata, Yuita Arum Sari, Edy Santoso

“…Therefore, the World Health Organization (WHO) has designated Coronavirus as a pandemic. This results in all activities that were previously face-to-face or offline (offline) becoming online (online), including teaching and learning activities. …”
Get full text

Evaluation of host immune responses to Mycobacteriophage Fionnbharth by route of delivery by Thomas Smytheman, Tiffany Pecor, Dana E. Miller, Debora Ferede, Suhavi Kaur, Matthew H. Harband, Hazem F. M. Abdelaal, Carlos A. Guerrero-Bustamante, Krista G. Freeman, Whitney E. Harrington, Lisa M. Frenkel, Graham F. Hatfull, Rhea N. Coler, Sasha E. Larsen

“…We found that aerosol delivery disperses phage across all lung lobes where M.tb is also found after experimental infection by the same route. …”
Get full text

A Circulating miRNA-Based Scoring System Established by WGCNA to Predict Colon Cancer by Da Qin, Rui Wei, Si Liu, Shengtao Zhu, Shutian Zhang, Li Min

“…After correlation analysis, green (cor=0.77, p=3×10‐25) and yellow (cor=0.65, p=6×10‐16) modules were strongly correlated with cancer development. 20 hub genes were found after hub gene analysis in these DEmiRs by cytoscape. Among all these hub genes, hsa-miR-23a-3p (OR=2.6391, p=6.23×10‐5) and hsa-miR-663a (OR=1.4220, p=0.0069) were identified as an independent risk factor of colon cancer by multivariate regression. …”
Get full text

Knee phenotypes distribution according to CPAK classification in Turkish population by Vahit Emre Özden, Göksel Dikmen, Kayahan Karaytuğ, Arda Mavi, Yılmaz Onat Köylüoğlu, İsmail Remzi Tözün

“…The Sectra workstation program was used for all radiological measurements. Results: In the nonarthritic group, CPAK distribution was 20.9% type I (n=245), 2.5% type II (n=30), 0.08% type III (n=1), 46.67% type IV (n=545), 7.7% type V (n=91), 0.7% type VI (n=9), 18% type VII (n=211), 2.9% type VIII (n=35), 0.2% type IX (n=3). …”
Get full text

Snacking Behaviour and Its Determinants among College-Going Students in Coastal South India by Prasanna Mithra, Bhaskaran Unnikrishnan, Rekha Thapar, Nithin Kumar, Sharana Hegde, Anjali Mangaldas Kamat, Vaman Kulkarni, Ramesh Holla, B. B. Darshan, Kanchan Tanuj, Vasudev Guddattu, Avinash Kumar

Get full text

Application of fourier transform infrared vibrational spectroscopy in identifying early biochemical changes in lipid profiles of individuals undergoing Roux-en-y gastric bypass by Amanda Motta de Bortoli, Márcia Helena Cassago Nascimento, Blanca Elena Guerrero Daboin, Beatriz Bobbio de Brito, Luiza Recla Pessotti, Paulo Roberto Filgueiras, Andressa Bolsoni Lopes, Valerio Garrone Barauna, Fabiano Kenji Haraguchi

“…A significance level of p < 0.05 was set for all tests. The university hospital’s Research Ethics Committee approved the study (protocol CAAE 59075722.7.0000.5071). …”
Get full text

A randomized controlled, trial on effects of mobile phone text messaging in combination with motivational interviewing versus standard infant feeding counselling on breastfeeding a... by Moleen Zunza, Lehana Thabane, Louise Kuhn, Christine Els, Carl Lombard, Mark F. Cotton, Taryn Young

“…Results Using block randomization mother-child pairs (n = 276) were randomly allocated to receive intervention (n = 138) or standard infant feeding counselling (n = 138), of whom 105 and 101 mother-child pairs in the intervention group and standard care group, respectively, completed all four study visits. Exclusive breastfeeding rate at 24 weeks in the intervention group was 6% (6/105) and 7% (7/101) in the standard care group, rate difference − 1% (95% CI -6–4%). …”
Get full text

Prevalence of Preoperative Anxiety and Associated Factors Among Surgical Patients: Systematic Review and Meta-Analysis in Ethiopia by Magarsa Lami, Abraham Negash, Jerman Dereje, Ahmed Hiko, Sinetibeb Mesfin, Arsema Gebreyesus, Nano Belama, Nesredin Ahmed Omer, Bikila Balis, Usmael Jibro

“…Methods: In this study, all observational study designs conducted in Ethiopia were included while studies that did not report our main outcome of interest or did not meet the quality criteria by Joanna Briggs Institute (JBI) critical appraisal techniques were excluded. …”
Get full text

Vagal Blocking Improves Glycemic Control and Elevated Blood Pressure in Obese Subjects with Type 2 Diabetes Mellitus by S. Shikora, J. Toouli, M. F. Herrera, B. Kulseng, H. Zulewski, R. Brancatisano, L. Kow, J. P. Pantoja, G. Johnsen, A. Brancatisano, K. S. Tweden, M. B. Knudson, C. J. Billington

“…In DM2 subjects with elevated BP (n=15), mean arterial pressure reduced by 7±3 mmHg and 8±3 mmHg (P=0.04, baseline 100 ± 2 mmHg) at 1 week and 12 months. All subjects MAP decreased by 3 ± 2 mmHg (baseline 95 ± 2 mmHg) at 12 months. …”
Get full text

Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA by Paolo Peruzzo, Natascha Bergamin, Martina Bon, Sara Cappelli, Alessandra Longo, Elisa Goina, Cristiana Stuani, Emanuele Buratti, Andrea Dardis

“…Results Modified U1-3, U1+1 and U1+6 snRNAs were all able to increase, in a dose-dependent manner, the inclusion of exon 2 within the transcript derived from the GAA minigene harbouring the c.-32-13T>G variant. …”
Get full text

Perancangan dan Implementasi Sistem Informasi Deteksi Kesesuaian Pemanfaatan Ruang Berbasis Web dengan Fitur Geo-Intersection Pada POSTGIS by Issa Arwani, Widhy Hayuhardhika Nugraha Putra, Ghazian Hamdi, Tsania Dzulkarnain

“…Based on the test results, the system functionally runs well on all browsers without critical issues. It is included in the excellent category with a grade B scale for usability aspects. …”
Get full text

Erroneous Classification and Coding as a Limitation for Big Data Analyses: Causes and Impacts Illustrated by the Diagnosis of Clavicle Injuries by Robert Raché, Lara-Sophie Claudé, Marcus Vollmer, Lyubomir Haralambiev, Denis Gümbel, Axel Ekkernkamp, Martin Jordan, Stefan Schulz-Drost, Mustafa Sinan Bakir

“…Billing codes and discharge summaries were the most error-prone categories, with error rates of 64% and 36% of all misclassified cases, respectively. Over three-quarters of the cases with discharge summary errors also exhibited errors in other categories, while billing errors co-occurred with other category errors in just over half of the cases (<i>p</i> < 0.001). …”
Get full text

Planetary health education in undergraduate medical education in Germany: results from structured interviews and an online survey within the national PlanetMedEd Project by Fabio Grieco, Sandra Parisi, Anne Simmenroth, Michael Eichinger, Michael Eichinger, Janina Zirkel, Janina Zirkel, Sarah König, Jana Jünger, Jana Jünger, Eva Geck, Eva-Maria Schwienhorst-Stich

“…This study therefore aimed (a) to assess the current implementation of Planetary Health in undergraduate medical education in Germany and (b) to explore its characteristics as a foundation to develop evidence-informed recommendations for mainstreaming Planetary Health Education in medical schools in Germany.MethodsThe study comprised structured interviews followed by an online survey, both targeting all 39 medical schools in Germany. In 2021, structured interviews were conducted with students, educators and deanery staff at medical schools. …”
Get full text

Evaluating cutinase from Fusarium oxysporum as a biocatalyst for the degradation of nine synthetic polymer by Maycon Vinicius Damasceno de Oliveira, Gabriel Calandrini, Clauber Henrique Souza da Costa, Carlos Gabriel da Silva de Souza, Cláudio Nahum Alves, José Rogério A. Silva, Anderson H. Lima, Jerônimo Lameira

“…We demonstrated that important conserved regions, such as the Ser-Asp-His catalytic triad, exist in the enzyme’s catalytic site and that all Cut enzymes from different organisms have the same region to couple with the polymer structures.…”
Get full text

Noninvasive oxygenation and ventilation strategies for viral acute respiratory failure: a comprehensive systematic review and meta-analysis by Fredy Leonardo Carreño-Hernández, Sergio Prieto, Daniela Abondando, Jairo Alejandro Gaitán, Yenny Rocío Cárdenas -Bolívar, Adriana Beltrán, Jorge Iván Alvarado-Sánchez, Joseph L. Nates

“…The primary outcome was the all-cause ICU mortality rate. Methods A systematic review was conducted following the Cochrane guidelines and PRISMA reporting guidelines. …”
Get full text

Identification of RNA Editing Sites Reveals Functional Modifications with the Addition of Methionine to the Daily Rations of Yaks by Shiyu Wu, Xinrui Liu, Yaxin Liu, Shikai Wang, Wei Peng, Ming Zhang, Binglin Yue, Hui Wang, Jikun Wang, Jincheng Zhong, Fang Sun, Yixi Kangzhu, Jiabo Wang

“…Methionine is an amino acid necessary for the growth and development of all animals. Glutathione produced during methionine metabolism can reduce damage to cells caused by oxidative stress. …”
Get full text

Color Stability and Surface Properties of PMMA/ZrO2 Nanocomposite Denture Base Material after Using Denture Cleanser by Mohammed M. Gad, Reem Abualsaud, Shaimaa M. Fouda, Ahmed Rahoma, Ahmad M. Al-Thobity, Soban Q. Khan, Sultan Akhtar, Khalid S. Al-Abidi, Mohamed S. Ali, Fahad A. Al-Harbi

“…The immersion time in denture cleansers significantly affected all tested properties (P<0.001). Within denture cleansers, NaOCl showed the highest adverse effects (P<0.05) while Renew showed the least adverse effects. …”
Get full text