Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease by Hua-xiong Zhang, Dilmurat Hamit, Qing Li, Xiao Hu, San-feng Li, Fu Xu, Ming-yuan Wang, Guo-qing Bao, Hong-yan Li

“…Finally, we discovered that all biomarkers could bind to MLT with a strong binding energy. …”
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Thrombotic vs. Bleeding Events of Interruption of Dual Antiplatelet Therapy within 12 Months among Patients with Stent-Driven High Ischemic Risk Definition following PCI by Hao-Yu Wang, Bo Xu, Chen-Xi Song, Chang-Dong Guan, Li-Hua Xie, Yan-Yan Zhao, Zhong-Xing Cai, Sheng Yuan, Ke-Fei Dou

“…This difference was driven mainly by all-cause death (1.8% vs. 0.7%) and MI (1.3% vs. 0.5%). …”
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Establishment of Fermentation Kinetic Model of Streptococcus thermophilus JM108 by Wen SUN, Baolei LI, Baochao HOU, Weilian HONG, Jian HE, Chao LIANG, Yu ZHANG, Chaoxin MAN, Yujun JIANG, Ling GUO

“…The R2 values for the three cases were 0.9974, 0.9947, and 0.9964, respectively, all greater than 0.99. The errors between the fitted and experimental values were less than 15%, indicating a good fit. …”
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Virulence potential of faecal <i>Escherichia coli</i> strains isolated from healthy cows and calves on farms in Perm Krai by V. S. Mihailovskaya, N. B. Remezovskaya, I. N. Zhdanova, M. Starčič Erjavec, M. V. Kuznetsova

“…Among the studied E. coli strains, 77.6 % were resistant to ampicillin, 49.0 % to tetracycline, 20.4 % to chloramphenicol, 16.3 % to cefoperazone, 16.3 % to ceftriaxone, 16.3 % to aztreonam, 14.3 % to cefepime, 10.2 % to norfloxacin, 10.2 % to ciprofloxacin, 6.1 % to levofloxacin and 2.0 % to gentamicin. All strains were sensitive to meropenem and amikacin. 32.7 % of the studied E. coli strains were found to be multidrug resistant, as they were resistant to at least three groups of antibiotics. …”
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What’s Going On With Me and How Can I Better Manage My Health? The Potential of GPT-4 to Transform Discharge Letters Into Patient-Centered Letters to Enhance Patient Safety: Prospe... by Felix Eisinger, Friederike Holderried, Moritz Mahling, Christian Stegemann–Philipps, Anne Herrmann–Werner, Eric Nazarenus, Alessandra Sonanini, Martina Guthoff, Carsten Eickhoff, Martin Holderried

“…While the readability and patient centricity of the transformed letters are well-established, they do not fully address all patient safety–relevant information, resulting in the omission of key aspects. …”
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Calm ocean, stormy sea: atmospheric and oceanographic observations of the Atlantic during the Atlantic References and Convection (ARC) ship campaign by L. Köhler, L. Köhler, J. Windmiller, D. Baranowski, M. Brennek, M. Ciuryło, L. Hayo, D. Kȩpski, S. Kinne, B. Latos, B. Lobo, T. Marke, T. Nischik, D. Paul, P. Stammes, A. Szkop, O. Tuinder

“…To illustrate the data sets provided, we present examples of measurements taken during the three crossings of the ITCZ and during a storm in the Roaring Forties in the South Atlantic at the end of the campaign. An overview of all available data sets, including DOIs and download links, can be found in <span class="cit" id="xref_text.1"><a href="#bib1.bibx21">Köhler et al.…”
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Extreme Temperature Events in Kazakhstan and Their Impacts on Public Health and Energy Demand by Parya Broomandi, Alfrendo Satyanaga, Mehdi Bagheri, Mostafa Hadei, David Galán‐Madruga, Ali Mozhdehi Fard, Adib Roshani, Aram Fathian, Amir Nourian, Michael Leuchner, Klaus Reicherter, Mehdi Hamidi, Prashant Kumar, Jong Ryeol Kim

“…The impact of heatwaves on various health conditions, notably consistent and statistically significant rises in all‐cause and cardiovascular mortalities, is observed. …”
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Factors associated with occupational injuries among bricklayers and carpenters in Building Construction: insights from a mixed methods study in Osun State, Nigeria by Temitope Olumuyiwa Ojo, Adedeji Ayodeji Onayade, Nisha Naicker

“…Binary logistic regression analysis was conducted to assess the factors influencing OIs, p-value less than 0.05 was taken as statistically significant. Results All respondents were male. The mean age was 51.3.7 ± 14.7 years for bricklayers and 50.0 ± 11.5 years for carpenters. …”
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The Correlation between FSTL1 Expression and Airway Remodeling in Asthmatics by Yahui Liu, Tian Liu, Jinxiang Wu, Tao Li, Xingai Jiao, Haiqing Zhang, Jiping Zhao, Junfei Wang, Lin Liu, Liuzhao Cao, Shuo Li, Jiawei Xu, Jianfeng Xu, Xiaohui Ma, Lei Yang, Liang Dong

“…We examined FSTL1 levels in 32 asthmatics and 25 controls. All subjects enrolled had routine blood tests, spirometry, and impulse oscillometry performed. …”
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Prediksi Detak Jantung Berbasis LSTM pada Raspberry Pi untuk Pemantauan Kesehatan Portabel by Ahmad Foresta Azhar Zen, Eko Sakti Pramukantoro, Kasyful Amron, Viera Wardhani, Putri Annisa Kamila

“…An estimated 17.9 million people succumbed to CVDs in 2019, constituting 32% of all global deaths. Detecting heart abnormalities as early as possible is crucial to prevent CVD-related fatalities. …”
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Global, regional and national burdens of cardiovascular disease attributable to secondhand smoke from 1990–2019: an age-period-cohort analysis by Hong Jiang, Xiang-Bin Pan, Xiaofei Li, Shouzheng Wang, Zeye Liu, Peijian Wei, Fengwen Zhang, Wen-Bin Ou-yang

“…In 2019, CVD accounted for 45.9% of all deaths attributable to secondhand smoke among both sexes globally. …”
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Early health technology assessment of tongue swab for non-sputum based pulmonary tuberculosis diagnosis in ThailandResearch in context by Langming Mou, Teerawat Wiwatpanit, Apiwat Piriyapol, Puwadol Chawengkul, Janjira Thaipadungpanit, Puttarin Kulchaitanaroaj, Yot Teerawattananon, Yi Wang

“…Findings: The landscape review identified the clinical workflow and reimbursement process of all PTB diagnostic tests in Thailand. The gap of tuberculosis management was around diagnosis and treatment. …”
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Effectiveness of lateral femoral cutaneous and femoral nerve block in managing postoperative pain for hemiarthroplasty patients by Kazi Mahzabin Arin, Shofina Sultana, Ayesha Sultana, Abdul Hannan Mohammad, Chandra Shekhar Karmakar, AKM Akhtaruzzaman

“…Methods: Sixty patients were randomly assigned to either the fascia iliaca compartment (FIC) block group or the lateral femoral cutaneous nerve and femoral nerve (LFCN plus FN) block group. All patients received a subarachnoid block for surgery. …”
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Relationship Between Myocardial Strain and Extracellular Volume: Exploratory Study in Patients with Severe Aortic Stenosis Undergoing Photon-Counting Detector CT by Costanza Lisi, Victor Mergen, Lukas J. Moser, Konstantin Klambauer, Jonathan Michel, Albert M. Kasel, Hatem Alkadhi, Matthias Eberhard

“…Significant correlations were identified between the global longitudinal, circumferential, and radial strains and the CT-derived left ventricular ejection fraction (EF) (all, <i>p</i> < 0.001). Patients with low-flow, low-gradient AS and reduced EF exhibited lower median global longitudinal strain values compared with those with high-gradient AS (−15.2% versus −25.8%, <i>p</i> < 0.001). …”
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Beyond Chaos in Fractional-Order Systems: Keen Insight in the Dynamic Effects by José Luis Echenausía-Monroy, Luis Alberto Quezada-Tellez, Hector Eduardo Gilardi-Velázquez, Omar Fernando Ruíz-Martínez, María del Carmen Heras-Sánchez, Jose E. Lozano-Rizk, José Ricardo Cuesta-García, Luis Alejandro Márquez-Martínez, Raúl Rivera-Rodríguez, Jonatan Pena Ramirez, Joaquín Álvarez

“…By quantifying the convex envelope generated by the 2D projection of the system into all its phase portraits, the changes in the area of the system, as well as the volume of the attractor, are characterized. …”
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Cytoreductive Nephrectomy and Nephrectomy/Complete Metastasectomy for Metastatic Renal Cancer by Paul Russo, Mark Synder, Andrew Vickers, Varuni Kondagunta, Robert Motzer

“…Sixty-one patients (67%) had nephrectomy with removal of all metastatic sites (nephrectomy/complete metastasectomy) and 30 (33%) had cytoreductive nephrectomy alone. …”
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Analysis of Optimal Health-Related Quality of Life Measures in Patients Waitlisted for Lung Transplantation by Junko Tokuno, Toyofumi F Chen-Yoshikawa, Toru Oga, Takahiro Oto, Tomoyo Okawa, Yoshinori Okada, Miki Akiba, Masaki Ikeda, Daisuke Nakajima, Masatsugu Hamaji, Hideki Motoyama, Akihiro Aoyama, Maki Isomi, Kazuo Chin, Hiroshi Date

“…Compared to the MRF-26 and SRI, the score distribution of the SGRQ was skewed toward the worse ends of the scale. All domains of the MRF-26 and SRI were significantly correlated with the SGRQ. …”
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Mangrove biomass productivity and sediment carbon storage assessment at selected sites in Mauritius: the effect of tidal inundation, forest age and mineral availability by M D D Doodee, S D D V Rughooputh, S Jawaheer

“…Total organic carbon (TOC), sediment carbon storage, and all essential nutrients for plant growth were analysed using standard methods. …”
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Development of the Dutch translational knowledge agenda for inherited metabolic diseases by I. J. Hieltjes, J. H. van derLee, M. C. Groenendijk, G. vanHaaften, P. M. vanHasselt, R. J. Lunsing, G. J. J. vanProoijen, E. M. deRuiter, F. J. vanSpronsen, N. M. Verhoeven‐Duif, A. deVreugd, M. Wagenmakers, H. Zweers, H. Dekker, H. R. Waterham, C. D. vanKarnebeek, R. J. A. Wanders, R. A. Wevers

“…The 462 proposed questions were categorized and prioritized during a meeting attended by 22 representatives of all stakeholder groups. The resulting top 10 research questions cover multiple themes, i.e. prediction of disease progression, development of novel tools, mechanistic insights, improved diagnostics, therapeutic integration of multi‐omics techniques, assessment of impact on daily life, expanding treatment avenues, optimal study designs, effect of lifestyle interventions, and data utilization using FAIR principles. …”
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Investigating shared risk variants and genetic etiology between Alzheimer’s disease and three stress-related psychiatric disorders: a large-scale genome-wide cross-trait analysis by Weijia Dang, Tianqi Hao, Ning Li, Hualin Zhang, Ziqi Li, Hongmei Yu, Yalu Wen, Deqiang Zheng, Long Liu

“…Functional annotation and gene-set enrichment analysis indicated that 12 genes for comorbidity shared between patients with AD and all three stress-related psychiatric disorders were enriched in the spleen, pancreas, and whole blood.ConclusionThese results advance our knowledge of the shared genetic origins of comorbidities and pave the way for advancements in the diagnosis, management, and prevention of stress-related AD.…”
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