Enhancing Learners’ Engagement and Performance in Learning through E-Resources and Services: National Open University of Nigeria Students as Beneficiaries by Patricia Ngozi Ofodu, Loveth Ogoegbunam Ekwueme

“…The findings from the study revealed that there are some e-resources available for the users’; there are users that are making use of the electronic resources occasionally and daily, while some don’t use e-resources at all. The study also revealed that the use of electronic resources influenced the users’ class tests, assignments, seminar presentations and more, while there was also evidence of non-assistance from the use of e-resources in some students’ learning pursuits. …”
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Cohort profile: Noncommunicable diseases and ideal cardiovascular health among people living with and without HIV in Zambia and Zimbabwe (NCDzz cohort) by Gilles Wandeler, Samuel Bosomprah, Cleophas Chimbetete, Belinda Varaidzo Chihota, Guy Muula, Carolyn Bolton-Moore, Tinei Shamu, Ardele Mandiriri, Esau Banda

“…Here, we describe the study design and population and evaluate their ideal cardiovascular health (ICVH) using the Life’s Simple 7 (LS7) score according to the American Heart Association.Participants Antiretroviral therapy-naïve people living with HIV (PLWH) and people living without HIV (PLWOH) 30 years or older were recruited from three primary care clinics in Lusaka and Harare, and underwent comprehensive clinical, laboratory and behavioural assessments. All study measurements are repeated during yearly follow-up visits. …”
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Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome by Xinlei Sun, Shuang Qu, Fenglian Zhou, Fujie Shi, Yunfei Wu, Lin Gu, Minghui Liu, Zhen Bian, Lei Shi, Zhihong Liu, Yuan Liu, Ke Zen

“…Through single-cell sequencing analysis of Stx2-B-bound peripheral white blood cells sorted by flow cytometry, we observe that nearly all monocytes exhibit strong Stx2-B binding, whereas less than 10% of neutrophils are associated with Stx2-B, albeit with a lower affinity. …”
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Association of dietary niacin intake with osteoporosis in the postmenopausal women in the US: NHANES 2007–2018 by Li Li, Wankun Liang, Bing Deng, Yue Jiang, Xiaomin Huang, Yanlin Zhang, Tianrui Lu, Lu Wang, Yunxiang Xu, Guizhen Chen

“…Additionally, we performed stratified and interaction analyses to illustrate the stability of the observed relationships across different subgroups.ResultsAfter adjusting for all covariates, there was a significant inverse association with osteoporosis (OR = 0.87; 95% CI: 0.77–0.97; p = 0.016). …”
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Effect of Different Surface Treatments on the Micro-Shear Bond Strength and Surface Characteristics of Zirconia: An In Vitro Study by Ann Sales, Shobha J. Rodrigues, M. Mahesh, Kishore Ginjupalli, Thilak Shetty, Umesh Y. Pai, Sharon Saldanha, Puneeth Hegde, Sandipan Mukherjee, Vignesh Kamath, Prashant Bajantri, N. Srikant, Ravindra Kotian

“…After the surface treatment, all specimens were ultrasonically cleaned and 10 resin cement cylinders were attached to the zirconia discs in each group. …”
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3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications by Sarvesh Kumar Avinashi, Rajat Kumar Mishra, Shweta, Saurabh Kumar, Amreen Shamsad, Shama Parveen, Surajita Sahu, Savita Kumari, Zaireen Fatima, Sachin Kumar Yadav, Monisha Banerjee, Monalisa Mishra, Neeraj Mehta, Chandki Ram Gautam

“…S. pyogene, S. typhi and E. coli. at 10 mg/ml, indicating its potential effectiveness in inhibiting all of these pathogens. Genotoxicity and cytotoxicity tests were also performed on rearing Drosophila melanogaster, and these findings did not detect any trypan blue-positive staining, which further recommended that the existence of composites did not harm the larval gut. …”
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Results of sea buckthorn breeding in the Southern Urals by A. A. Vasiliev, F. M. Gasimov, V. S. Ilyin

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Protocol for an adaptive platform trial of intended service user-derived interventions to equitably reduce non-attendance in eye screening programmes in Botswana, India, Kenya and... by Min Kim, David Macleod, Michael Gichangi, Andrew Bastawrous, Matthew J Burton, Jacqueline Ramke, Oathokwa Nkomazana, James R Carpenter, Sailesh Mishra, Shalinder Sabherwal, Luke Allen, Sarah Karanja, Ari Ho-Foster, Nigel Bolster, Malebogo Tlhajoane, Bakgaki Ratshaa

“…The specific design of cluster RCTs will be determined by our research team once the intervention is known, but the population and outcome will be the same across all trials.This adaptive platform trial will be used to identify effective service modifications, driving continuous improvements in access.Ethics and dissemination This trial has been approved by the research ethics committee at the London School of Hygiene & Tropical Medicine (ref: 29549). …”
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Effects of time restricted feeding combined with Lacto Ovo vegetarian diet on metabolic associated fatty liver disease management: a randomized clinical trial by Mahshad Shafiee, Amir Sadeghi, Fateme Ghafouri-Taleghani, Maryam Nilghaz, Maryam Ghods, Behnaz Narimani, Azita Hekmatdoost, Atoosa saidpour

“…The intervention group showed significant reductions in weight (-8.07 ± 4.31 kg), BMI (-2.70 ± 1.32 kg/m2), waist circumference (-8.00 ± 4.06 cm), as well as ALT (-17.14 ± 14.33 U/L), GGT (-21.09 ± 24.06 U/L), Fatty Liver Index (-26.90 ± 15.81), insulin levels (-3.89 ± 4.69 mU/L), and TNF-α (-11.85 ± 12.52 pg/mL) compared to the control group (all P < 0.05). Lipid profiles also improved with a reduction in triglycerides (-46.85 ± 54.55 mg/dL) and an increase in HDL-C (3.91 ± 5.07 mg/dL) in the intervention group compared to the control group (P < 0.05). …”
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Performance analysis of Leica Biosystems p16 monoclonal antibody in oropharyngeal squamous cell carcinoma by Selvam Thavaraj, Max Robinson, Shubham Dayal, Claire Bowen

“…Conclusion LBS p16 monoclonal antibody demonstrated high concordance with CINtec p16 IHC assay across all the endpoints, suggesting a potential use of LBS RTU p16 clone in detecting p16 protein in oropharyngeal cancer cases.…”
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Susceptibility to Ventricular Arrhythmias Resulting from Mutations in FKBP1B, PXDNL, and SCN9A Evaluated in hiPSC Cardiomyocytes by Hector Barajas-Martinez, Maya Smith, Dan Hu, Robert J. Goodrow, Colleen Puleo, Can Hasdemir, Charles Antzelevitch, Ryan Pfeiffer, Jacqueline A. Treat, Jonathan M. Cordeiro

“…Only the proband carrying all 3 mutations displayed the ERS/BrS phenotype, whereas one nor two mutations alone did not produce the clinical phenotype. …”
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Finding the Intersection of Neuroplasticity, Stroke Recovery, and Learning: Scope and Contributions to Stroke Rehabilitation by Leeanne Carey, Alistair Walsh, Achini Adikari, Peter Goodin, Damminda Alahakoon, Daswin De Silva, Kok-Leong Ong, Michael Nilsson, Lara Boyd

“…A cluster concept map (network graph) was generated from the results; indicating the concept nodes, strength of link between nodes, and the intersection between all three concepts. We identified 23 common themes (topics) and the top 30 articles that best represent the intersecting themes. …”
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Trends and distribution patterns of infant mortality and maternal HIV positivity in South Africa: A decade review (2007 - 2016) by M Makhele, N Ledibane, H Ramatsoma, A Musekiwa

“…Spearman’s rank-order correlation (rho) was used to correlate infant mortality with data from the 2007 ANCHSS. All analyses were performed with Stata version 16.0. …”
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Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs by Masaki Shibuya, Masafumi Fujinaka, Mako Yonezawa, Natsumi Nishimura, Hitoshi Uchinoumi, Hiroshi Sunahara, Kenji Tani, Eiji Kobayashi, Motoaki Sano

“…When saturated hydrogen saline was dripped intravenously, almost all of the hydrogen was expelled during its passage through the lungs and could not be supplied to the arterial side.…”
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Neural Correlates of Social Perception Deficit in Schizophrenia: An Event-related Potential Study by Jiang-juan Li, Xin-ping Li, Jia-min Han, Yi-fan Sun, Xiao-hong Liu, Xue-zheng Gao, Li-min Chen, Zhen-he Zhou, Hong-liang Zhou

“…Methods: Participants included 33 schizophrenia patients and 35 healthy controls (HCs). All participants underwent electroencephalogram recording while completing the Emotion Intensity Recognition Task (EIRT). …”
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Development and validation of the age-associated dementia policy (AgeD-Pol) computer simulation model in the USA and Europe by Anand Viswanathan, Lee H Schwamm, Krishna P Reddy, Emily P Hyle, Fatma M Shebl, Kenneth A Freedberg, Julia H A Foote, Yiqi Qian, Shibani S Mukerji, Nattanicha Wattananimitgul, Ankur Pandya

“…Model projections demonstrated a good fit to all three cohorts (MAPE, 0.9%–9.0%). Similarly, model-projected survival provided good fit to the Rotterdam (RMSE, 1.9–3.6 among those with and without AAD) and KPNC cohorts (RMSE, 7.6–18.0 among those with AAD).Conclusions The AgeD-Pol model performed well when validated to published data for AAD cumulative incidence and mortality and provides a useful tool to project the AAD disease burden for health systems planning in the USA.…”
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Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan by Chiara Trevisan, Amber Hadermann, Stephen Raimon Jada, Raphael A. Abong, Yak Yak Bol, Joseph N. Siewe Fodjo, Katja Polman, Robert Colebunders

“…Methodology/Principal Findings A hospital-based cross-sectional study was conducted in 2023 at Maridi hospital in Maridi County, an onchocerciasis endemic area in South Sudan. All pregnant or one-week post-partum women willing to participate were interviewed, clinically examined, tested with the Ov16 Bioline rapid diagnostic test (RDT) and skin snipped for O. volvulus detection. …”
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Methodological aspects in gastroenteric methane evaluation trial in water buffalo by Maria Chiara La Mantia, Emanuela Rossi, Francesco Cenci, David Meo Zilio, Roberto Steri, Miriam Iacurto, Antonella Chiariotti

“…Nevertheless, metagenomic analysis must be carried out to verify whether the species composition is comparable. All DNA extraction methods were satisfying: Quick Extract was the easiest to perform, WUR resulted in the highest amount of DNA, and Kit Maxwell was the one that gave the overall best performance. …”
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KAP of influenza, streptococcal pneumonia, and herpes zoster among community-dwelling older adults with chronic diseases in Nanjing city: a cross-sectional survey by Zhengkai SHEN, Siyu TIAN, Zhiyong WANG, Wenjing ZHU, Lirong DONG, Jinshui XU

“…ResultsOf the 6 790 (96% of all residents surveyed) participants with valid responses, only 2 260 (33.3%) had adequate knowledge (correctly answering 8 out of 12 questions about the three diseases), and χ2 test results showed that participants aged 60 – 70 years and those with higher levels of education had significantly higher knowledge (both P < 0.05). …”
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Echocardiographic phenotypes of diabetic myocardial disorder: evolution over 15 months follow-up in the ARISE-HF trial by Thomas H. Marwick, Carolyn Lam, Yuxi Liu, Stefano Del Prato, Julio Rosenstock, Javed Butler, Justin Ezekowitz, Nasrien E. Ibrahim, W. H. Wilson Tang, Faiez Zannad, Riccardo Perfetti, James L. Januzzi

“…In 669 patients followed over 15 months, there was a similar small decrement in VO2 in all groups. Conclusions Among individuals with T2DM and SBHF, reduced functional capacity is most prevalent in those with multiple physiological disturbances. …”
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