Efficacy of Shenqi Pollen Capsules for High-Altitude Deacclimatization Syndrome via Suppression of the Reoxygenation Injury and Inflammatory Response by Binfeng He, Mingdong Hu, Zhihui Liang, Qianli Ma, Yunhai Zi, Zhiwei Dong, Qi Li, Yongjun Luo, Guisheng Qian, Liang Guo, Kexiong Lin, Zhenyu Liu, Guansong Wang

“…Here, we investigated the mechanism as well as potential means to prevent HADAS using Shenqi pollen capsules (SPCs) in subjects with HADAS in a multicenter, double-blinded, randomized, placebo-controlled study. All subjects were at the same high altitude (3650 m) for 4-8 months before returning to lower altitudes. …”
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Structural Alteration of Medial Temporal Lobe Subfield in the Amnestic Mild Cognitive Impairment Stage of Alzheimer’s Disease by Pan He, Hang Qu, Ming Cai, Weijie Liu, Xinyi Gu, Qiang Ma

“…AD had lower GM densities than MCI, and MCI had lower GM densities than NC, but not all of the differences were statistically significant. …”
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Urinary concentrations of arsenic species in older Dutch adults and risk of chronic kidney disease by Hannah P. McKeon, Weiluan Chen, Jan Dirk te Biesebeek, Nanette G. Vrijenhoek, Jacqueline J.M. Castenmiller, Marcel J.B. Mengelers

“…Human biomonitoring (HBM) is used to measure internal (all-route) exposure to different As species. To assess the risk of internal As exposure, toxic relevant arsenic (TRA) (sum of arsenite (As(III)), arsenate (As(V)), and their methylation metabolites, monomethylarsonate (MMA) and dimethylarsinate (DMA)) in urine should be used.Morning urine samples of 288 Dutch adults (aged 52–91 years) were analysed for As(III), As(V), MMA, DMA, arsenobetaine (AsB) and total As using ICP-MS. …”
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Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease by Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead

“…Alzheimer's disease (AD) is a progressive neurodegenerative disease that accounts for two-thirds of all dementia cases, and age is the strongest risk factor. …”
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Molecular Docking Appraisal of Phytochemicals as Potential Inhibitors of PI3K/Akt Pathway for Breast Cancer Treatment by Magdalene Eno Effiong, Mercy Bella-Omunagbe, Israel Sunmola Afolabi, Shalom Nwodo Chinedu

“…The drug likeness, pharmacokinetic, and pharmacodynamic features of prospective docking leads were all anticipated. Result: Several potent inhibitors of the selected key driver proteins in PI3K/Akt/mTOR pathway were identified from P ostreatus . …”
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Exploring the role of different coping styles in mediating the relationship between dyadic adjustment status and postpartum depression among postnatal women: a single-centre, cross... by Jing Chen, Jing Deng, Fan Liu, Xiujing Guo, Yifei Tan

“…Data analysis encompassed correlation and mediation analyses based on structural equation modelling.Results EPDS scores were significantly correlated with all four dimensions of dyadic adjustments status as well as with both positive and negative coping styles. …”
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Purification, Preliminary Structural Characterization, and In Vitro Inhibitory Effect on Digestive Enzymes by β-Glucan from Qingke (Tibetan Hulless Barley) by Jialiang Hu, Yue Wu, Huifang Xie, Wanyin Shi, Zhiyuan Chen, Dan Jiang, Hui Hu, Xiangwei Zheng, Jian Xu, Yuejun Yang, Yuancai Liu

“…Qingke (Tibetan hulless barley, Hordeum vulgare L.) contains a high content of β-glucan among all the cereal varieties. Although β-glucan has multiple physiological functions, the physiological function of qingke β-glucan was few studied. …”
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Structured reporting of neuroendocrine tumors in PET/CT using [18F]SiTATE - impact on interdisciplinary communication by Anna Hinterberger, Lukas Trupka, Sophia Kortbein, Ricarda Ebner, Nicola Fink, Matthias F. Froelich, Dominik Nörenberg, Carmen Wängler, Björn Wängler, Ralf Schirrmacher, Adrien Holzgreve, Matthias Brendel, Stefanie Corradini, Christoph Auernhammer, Johannes Rübenthaler, Freba Grawe

“…FTRs and SRs were generated post-examination. All reports were evaluated by a radiologist and a surgeon through a questionnaire to determine their contribution to facilitating clinical decision-making and to assess their completeness, linguistic quality, and overall quality. …”
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Prediction of pulmonary function decline in fibrous interstitial lung abnormalities based on quantitative chest CT parameters by Dechun Li, Yingli Sun, Zongjing Ma, Bin Chen, Liang Jin, Ming Li

“…Methods Ninety-five cases of fibrous ILA including CT images and 64 normal control cases were collected. All patients completed pulmonary function tests within one week. …”
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The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana by John Gameli Deku, Mavis Puopelle Dakorah, Sylvester Yao Lokpo, Verner N. Orish, Francis Abeku Ussher, Godsway Edem Kpene, Vida Angmorkie Eshun, Eunice Agyei, Waldermer Attivor, James Osei-Yeboah

“…Bloodstream infections are among the top causes of morbidity and mortality in people of all ages, especially in immunocompromised patients in sub-Saharan Africa. …”
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Identifying malignant pleural effusion from tubercular pleural effusion by study of cancer ratio and cancer ratio plus by Subhankar Saren, Animesh Mandal, Amit Kumar Das, Ranjit Kumar Haldar, Sudipta Pandit

“…CR with levels above 20 showed very strong statistical association with MPE diagnosis in patients of pleural effusion (P<0.001). The mean CR plus in all patients was found to be 54.58±28.14. According to diagnosis, the means were 65.5645±22.576, 27.3255±24.356, and 43.1169±25.622 in MPE, TPE, and “Others,” respectively. …”
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Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for... by Jiyauddin Khan, Priyanjana Ghosh, Urmi Bajpai, Kountay Dwivedi, Daman Saluja

“…The top 10 hub genes were validated both for mRNA and protein expression, revealing they are significantly overexpressed in all studied cancers. Prognostic relevance showed that MCM4, MCM6, CCNA2, CDC20, and CHEK1 are associated with survival. …”
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Evaluation of Phytochemical, Antioxidant, and Memory-Enhancing Activity of Garuga pinnata Roxb. Bark and Bryophyllum pinnatum (Lam) Oken. Leaves by Ravin Bhandari, Sabina Gyawali, Nisha Aryal, Devika Gaire, Kalpana Paudyal, Abaru Panta, Pooja Panth, Dirgha Raj Joshi, Rabindra Kumar Rokaya, Pramod Aryal, Jitendra Pandey

“…(Burseraceae) is a medium-sized tree widely available all over the tropical regions of Asia. Bryophyllum pinnatum (Lam) Oken. …”
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Comparison of the efficacy of the modified S-P approach and the Ganz method for surgical hip dislocation in Pipkin I fractures: an early follow-up study by Hanwen Zhang, Wei Deng, Shengtao Wang, Yong Yin

“…Of these, 11 cases were treated with the mS-P approach and 12 cases were treated with the GSD approach. All patients were followed for 12–55 months, with a mean duration of 37.7 months. …”
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Scoring System for Lesions Induced by Different Strains of Newcastle Disease Virus in Chicken by Elawad A. Hussein, M. Hair-Bejo, Lawan Adamu, A. R. Omar, Siti S. Arshad, Elmutaz A. Awad, I. Aini

“…Chickens were euthanised on day 5 pi. In all previous experiments, tissues of brain, trachea, lung, caecal tonsil, liver, kidney, spleen, heart, proventriculus, intestine, and thymus were collected, fixed in 10% buffered formalin, embedded in paraffin, and sectioned. …”
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Evaluation of choices and time spent on an open online elective course by undergraduate medical students during the COVID-19 pandemic by Z Mfeka, A Turner, J E Wolvaardt, D Muganhiri

“…In 2020 there were 300 participants and in 2021 there were 329. All the students had one compulsory inclusion in the elective (Management and Leadership Short Course for Undergraduate Healthcare Students). …”
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Lesbian, gay, bisexual, and transgender clinical competence of health professionals in Poland and Spain: results of the health exclusion research in Europe (HERE) study by Piotr Karniej, Anthony Dissen, Łukasz Pietrzykowski, Raúl Juárez-Vela, Antonio Martinez Sabater, Janina Kulińska, Jakub Zieliński, Michał Czapla

“…Results suggest that a more tailored approach in professional education and training may be necessary to ensure all health workers possess adequate skills and attitudes toward LGBT care.…”
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Linear growth rate of vyrezub (Rutilus frisii Nordmann, 1840) in the Dnister River basin by V. Gurbyk, A. Mruk, L. Strembitskyi, A. Kucheruk

“…The incomplete biological analysis was carried out directly at the sampling site, measurements were carried out according to the generally accepted method without removing fish from the water. After measurements, all juveniles were released into their natural habitat alive and unharmed. …”
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Chronic Rhinosinusitis without Nasal Polyps in Asian Patients Shows Mixed Inflammatory Patterns and Neutrophil-Related Disease Severity by Dae Woo Kim, Kyoung Mi Eun, Eun Youn Roh, Sue Shin, Dong-Kyu Kim

“…Patients with CRSsNP (N=57), patients with CRSwNP (N=13), and a control group (N=10), who underwent endoscopic sinus surgery, were enrolled; uncinate process (UP) tissues were harvested from all patients. Homogenates were prepared from the UP of each group, and immunologic profiles were analyzed, including major cytokines (32 inflammatory mediators). …”
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Histological staining of tick bite skin biopsies for spirochetes and Powassan virus RNA by Jihane Oufattole, Anne Piantadosi, Sam R. Telford, Alvaro C. Laga, Isaac H. Solomon

“…POWV ISH was negative in all biopsies, including one laboratory confirmed case. …”
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