Association of hepatitis B virus DNA levels with efficacy and safety and the impact of antiviral therapy on prognosis in liver cancer patients receiving immune checkpoint inhibitor... by Hongxia Cui, Su Li, Wu Lv, Jing Xiang

“…Further subgroup analysis showed that there was no difference in OS between the high HBV DNA group and low HBV DNA group when all patients received antiviral treatment. No associations between baseline HBV DNA and PFS (HR = 1.08, 95% CI 0.90–1.29), ORR (OR = 0.91, 95% CI 0.65–1.28), or DCR (OR = 0.83, 95% CI 0.58–1.20) were observed. …”
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High clinical burden of classical homocystinuria in the United States: a retrospective analysis by Mahim Jain, Mehul Shah, Kamlesh M. Thakker, Andrew Rava, Agnes Pelts Block, Colette Ndiba-Markey, Lionel Pinto

“…During follow-up, 5.7% (n = 34) of the patients died. All events assessed were more prevalent in the 50 to < 100 µM group and ≥ 100 µM group compared with those in the < 50 µM group. …”
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Deep learning radiomics nomogram for preoperatively identifying moderate-to-severe chronic cholangitis in children with pancreaticobiliary maljunction: a multicenter study by Hui-min Mao, Kai-ge Chen, Bin Zhu, Wan-liang Guo, San-li Shi

“…The DLRN outperformed single-modality clinical, handcrafted radiomics, and DL radiomics models, with all integrated discrimination improvement values > 0 and P < 0.05. …”
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Inter-session Reliability of Magnetic Nerve Stimulation and Within-Session comparison to Electrical Nerve Stimulation in Evaluating Neuromuscular Function of Knee Extensor Muscles by Romina Ledergerber, Martin Keller

“…The inter-session reliability of MNS was good across all parameters (ICC = 0.78–0.95) with low CV for VA (4.9%) but high CV for RS, RD and ST (61.7%, 28.9%, 82%). …”
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Direct anastomosis indwelling needle puncture: a rapid and safe transitional hemodialysis access for patients with renal failure by Chunyan Wu, Jianbo Qing, Xiaoping Wang, Yunmei Li, Xin Zhou, Junnan Wu

“…Detailed assessments and records of VAT were performed for all patients, including the distance of thrombus from the anastomosis, residual blood flow at the VA anastomosis, and corresponding selection of the DAINP insertion site. …”
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Determination of Vibration Properties and Reliable Frequency Estimation for Synchronous Vibrations Through Improved Blade Tip Timing Techniques Without a Once-per-Revolution Sensor by Marios Sasakaros, Luca Mann, Markus Schafferus, Manfred Wirsum

“…Blade Tip Timing (BTT) is a promising technique for monitoring synchronous vibrations due to its non-intrusive nature and ability to monitor all blades at once. BTT generally employs a Once-per-Revolution (OPR) sensor that is mounted on the shaft for blade identification and deflection calculation. …”
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Recruiting participants for focus groups in health research: a meta-research study by Jonas Lander, Simon Wallraf, Dawid Pieper, Ronny Klawunn, Hala Altawil, Marie-Luise Dierks, Cosima John

“…We used a text extraction sheet to collect all relevant recruitment information from each study. …”
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A comparison of new and existing rootstocks to reduce canker of apple trees caused by Neonectria ditissima (Nectriaceae, Hypocreales) by Lucas A. Shuttleworth, Sonia Newman, Ioannis Korkos

“…The current study investigated the effect of rootstock selection on canker and tree death using eight common rootstocks M9 337, M9 337 with Golden Delicious (GD) interstock, M9 EMLA, MM106, M116, M26, Geneva® G11 and G41, in addition to six advanced selections from the NIAB East Malling apple breeding programme EMR-001—EMR-006, all grafted with Gala scions. One of the rootstocks, M9 377 was also grafted with a GD interstock. …”
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Microstructural modifications in bitumens rejuvenated by oil from pyrolysis of waste tires by Michela Alfe, Valentina Gargiulo, Giovanna Ruoppolo, Francesco Cammarota, Pietro Calandra, Cesare Oliviero Rossi, Valeria Loise, Michele Porto, Roberto Di Capua, Paolino Caputo

“…The blends were also investigated using atomic force microscopy, and the asphaltenic fraction was assessed via optical microscopy.Results and discussionAll the data consistently indicate that oil addition not only reduces the viscosity of bitumen and restores it to values close to the original unaged bitumen but also changes the intermolecular structure to recover the self-assembly pattern typical of the unaged sample. …”
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Phylogenomic analysis reveals exceptions to the co-evolution of ZAR1 and ZRK immune gene families in plants by Li Yang, Shengyi Liu, M. Eric Schranz, Klaas Bouwmeester

“…We also detected a large number of concerted gene losses in angiosperms, especially within the orders Fabales, Cucurbitales, Asterales, and Apiales. All analysed monocot genomes thus far examined, except for the aroid Colocasia esculenta, were previously reported to lack both ZAR1-A and ZRKs. …”
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Marker-assisted selection in the development of advanced apple-tree forms and donors combining scab resistance with increased fruit storability by I. I. Suprun, E. A. Egorov, A. I. Nasonov, E. V. Lobodina, S. V. Tokmakov, I. V. Stepanov

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Spatial Distribution of Tsetse Flies and Trypanosome Infection Status in a Vector Genetic Transition Zone in Northern Uganda by Robert Opiro, Okello Allele Moses, Robert Opoke, Francis A. Oloya, Esther Nakafu, Teresa Iwiru, Richard Echodu, Geoffrey M. Malinga, Joel L. Bargul, Elizabeth A. Opiyo

“…A total of 717 flies (406 females; 311 males) were caught, all belonging to the Glossina fuscipes fuscipes species. …”
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Development of a novel strategy for the quantification of ultra-trace impurity elements in high-purity magnesium using inductively coupled plasma tandem mass spectrometry by Liang Fu, Guangsheng Huang, Yaobo Hu, Xianhua Chen, Jingfeng Wang, Fusheng Pan

“…The results indicated that the limits of detection (LOD) were in the range of 0.02–18.5 ng L−1; the LODs of the challenging non-metallic elements Si and S were 18.5 and 12.2 ng L−1, respectively; and the LODs of all the other analytes were less than 10 ng L−1. …”
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Representativeness of the dabigatran, apixaban and rivaroxaban clinical trial populations to real-world atrial fibrillation patients in the United Kingdom: a cross-sectional analys... by Gregory Y H Lip, Sally Lee, Brigitta U Monz, Andreas Clemens, Martina Brueckmann

“…Objective Three oral anticoagulants have reported study results for stroke prevention in patients with atrial fibrillation (AF) (dabigatran etexilate, rivaroxaban and apixaban); all demonstrated superiority or non-inferiority compared with warfarin (RE-LY, ARISTOTLE and ROCKET-AF). …”
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End-tidal carbon dioxide-guided extracorporeal cardiopulmonary resuscitation improves neurological prognosis in patients: a single-center retrospective cohort study by Xiaozu Liao, Chen Gu, Zhou Cheng, Kepeng Liu, Qing Yin, Binfei Li

“…Methods: The medical records of all patients who received ECPR treated at Zhongshan City People's Hospital were collected between January 2020 and March 2023. …”
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Extensional forearc structures at the transition from Alaska to Aleutian Subduction Zone: slip partitioning, terranes and large earthquakes by Kahrizi, Amin, Delescluse, Matthias, Chamot-Rooke, Nicolas, Pubellier, Manuel, Bécel, Anne, Shillington, Donna, Nedimović, Mladen, Bulois, Cédric

“…Using legacy seismic profiles and modern multichannel seismic data, we update the structural map of the area, focusing on the intersection between trench-parallel, landward-dipping normal faults rooting in the plate interface and trench-oblique to trench-perpendicular normal faults, all showing signs of recent activity. We investigate for the first time the origin of the trench-parallel extension and explain the horsetail geometry of the Central Sanak Basin as the termination of a slip-partitioning right-lateral strike slip fault. …”
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Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study by Min Liu, Na Yin, Yuhang Zhu, Aili Du, Chunyuan Cai, Pengyuan Leng

“…Furthermore, the SMR analysis failed to identify significant associations between the expression levels of the HMGCR, PCSK9, and NPC1L1 genes and the risk of gout or elevated urate levels (SMR method: all P values &gt;0.05). Sensitivity analyses further confirmed the robustness of these results, with no significant heterogeneity or pleiotropy found.ConclusionThis study furnishes novel causal evidence supporting the potential genetic correlation between the use of lipid-lowering drugs and the incidence of gout as well as urate levels. …”
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Evaluation of two electronic-rehabilitation programmes for persistent knee pain: protocol for a randomised feasibility trial by Philip G Conaghan, Kim L Bennell, Mark Conner, Rana S Hinman, Sarah R Kingsbury, Elizabeth M A Hensor, Gretl A McHugh, Christine Comer, Dawn Groves-Williams, Rachel K Nelligan

“…Education and exercise treatment are advocated in all clinical guidelines; however, the increasing prevalence of persistent knee pain presents challenges for health services regarding appropriate and scalable delivery of these treatments. …”
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Exploring the clinical profiles and management of juvenile dermatomyositis in Africa: a survey of African rheumatology care providers by Jessica Perfetto, Laura B. Lewandowski, Dawn M. Wahezi, Vanessa Ogega, Joan Ahimbisibwe, Kate Webb, Christiaan Scott, Angela Migowa

“…Respondents represented all 5 African regions and described 216 children with JDM within the last 10 years. …”
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Correlation between depressive symptoms and cognitive function in middle-aged and elderly population in China: an analysis of CHARLS baseline data by Yuchao SUN, Jing FENG, Zihui LEI, Ge QU, Xinyan LI, Yong GAN

“…ResultsThe final analysis included 14 979 participants with a mean age of 58.05 ± 9.35 years and 51.18% (7 661) males. For all participants, the mean cognitive function score was 12.09 ± 3.54, and 33.3% (4 985) were classified as having depressive symptoms. …”
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