Comparison of the Effects of Mesenchymal Stem Cells with Their Extracellular Vesicles on the Treatment of Kidney Damage Induced by Chronic Renal Artery Stenosis by Crysthiane Saveriano Rubiao Andre Ishiy, Milene Subtil Ormanji, Edgar Maquigussa, Rosemara Silva Ribeiro, Antonio da Silva Novaes, Mirian Aparecida Boim

“…The increased expression of Col I and TGFβ in both kidneys was reduced by all the treatments, and these treatments also effectively increased the expression of the anti-inflammatory cytokine IL-10 in both kidneys; however, only ASCs were able to reduce the overexpression of the proinflammatory cytokine IL-1β in both kidneys of 2K-1C animals. …”
Get full text

Biomechanical comparison of locking femoral neck plate versus cannulated screws with or without a medial buttress plate in Pauwels type 3 femoral neck fractures by Yilmaz Onder, Tugrul Bulut, Osman Nuri Eroglu, Samet Ciklacandir, Yalcin Isler

“…The forces corresponding to 0.5 mm, 1 mm, 1.5 mm, and 2 mm displacement and failure loads were calculated in all groups. Results: The axial load values corresponding to 4 di!…”
Get full text

Characterization of microbiota signatures in Iberian pig strains using machine learning algorithms by Lamiae Azouggagh, Noelia Ibáñez-Escriche, Marina Martínez-Álvaro, Luis Varona, Joaquim Casellas, Sara Negro, Cristina Casto-Rebollo

“…The most relevant genera in this classification performance were Acetitomaculum, Butyricicoccus and Limosilactobacillus. All of which exhibited a relevant differential abundance between purebred animals using a Bayesian linear model. …”
Get full text

Assessment of Technology Readiness in Norwegian Older Adults With Long-Term Health Conditions Receiving Home Care Services: Cross-Sectional Questionnaire Study by Sverre Bergh, Jūratė Šaltytė Benth, Lisbeth Dyrendal Høgset, Britt Rydjord, Lars Kayser

“…ConclusionsThe technology readiness level varied in our cohort of Norwegian participants receiving home care. Not all elderly people have the eHealth literacy to fully benefit from digital health services. …”
Get full text

The Constellation of Macrovascular Risk Factors in Early Onset T2DM: A Cross-Sectional Study in Xinjiang Province, China by Mingchen Zhang, Jiangfeng Mao, Ablikm Tuerdi, Xiaoyun Zeng, Li Quan, Shan Xiao, Jun Zhu, Hua Yao

“…Compared to the control, early onset patients had higher blood pressure and worse lipid profiles (all P<0.01). More than half of the early onset T2DM patients already had macro- and microvascular complications, despite of their young age (39.5 ± 10.8) and short DM duration (6.6 ± 8.0). …”
Get full text

Variation in Phenolic, Mineral, Dietary Fiber, and Antioxidant Activity across Southern Tunisian Pearl Millet Germplasm by Tebra Triki, Samir Tlahig, Mohamed Ali Benabderrahim, Walid Elfalleh, Mahmoud Mabrouk, Mohamed Bagues, Hédi Yahia, Khaled Belhouchette, Ferdaous Guasmi, Mohamed Loumerem

“…The highest polyphenolic content from all genotypes was 1134.96 µg·g−1 DM (genotype Med.AG1.3). …”
Get full text

Significance of Tool Coating Properties and Compacted Graphite Iron Microstructure for Tool Selection in Extreme Machining by Anna Maria Esposito, Qianxi He, Jose M. DePaiva, Stephen C. Veldhuis

“…The results revealed that CGI microstructural variations only affected tool life for Tool A, with a 110% increase in tool life between machining CGI Grade B and Grade A, but that the effects were negligible for all other tools. Tool C had a 250% and 70% longer tool life compared to the next best performance (Tool A) for CGI Grade A and CGI Grade B, respectively. …”
Get full text

Fast and Slow Roasting of Alcohol- and Honey-infused Coffee Blends: A Comparative Study of PAH and N-PAH Emissions by Hsin-Chieh Kung, Chung-Hsien Hung, Kun-Hui Lin, Bo-Wun Huang, Nicholas Kiprotich Cheruiyot, Guo-Ping Chang-Chien

“…However, when considering all the coffee formulations, only the mass concentrations between the two roasting methods were statistically different (p = 0.05). …”
Get full text

Altered Coactive Micropattern Connectivity in the Default-Mode Network during the Sleep-Wake Cycle by Yan Cui, Qiao Chen, Yang Xia, Zeru Wang, Yujia Guo, Ge Zhang, Dezhong Yao, Daqing Guo

“…Three CAMP networks were observed in DMN activity, and they displayed greater FC and higher efficiency than the original DMN structure in all states of consciousness, implying more efficient information processing in the CAMP networks. …”
Get full text

The accumulation of harmful genes within the ROH hotspot regions of the Tibetan sheep genome does not lead to genetic load by Lixia Sun, Chao Yuan, Tingting Guo, Yaqin Bai, Zengkui Lu, Jianbin Liu

“…These genes exhibited highly conserved within the ROH hotspot regions across all Tibetan sheep populations. Employing the integrated haplotype score (iHS) method, we screened for selective sites within frequently observed ROH hotspot regions to elucidate genomic differences among Tibetan sheep populations. …”
Get full text

Parental Technoference and Child Problematic Media Use: Meta-Analysis by Jinghui Zhang, Qing Zhang, Bowen Xiao, Yuxuan Cao, Yu Chen, Yan Li

“…Age, gender, publication status, and type of problematic media use did not significantly moderate the relationship (all P>.05). ConclusionsThis meta-analysis provides robust evidence of the association between parental technoference and child problematic media use. …”
Get full text

Demineralized Freeze-Dried Bovine Cortical Bone: Its Potential for Guided Bone Regeneration Membrane by David B. Kamadjaja, Achmad Harijadi, Pratiwi Soesilawati, Eny Wahyuni, Nurul Maulidah, Akhsanal Fauzi, Fika Rah Ayu, Roberto Simanjuntak, R. Soesanto, Djodi Asmara, Andra Rizqiawan, Peter Agus, Coen Pramono

“…Demineralized freeze-dried bovine cortical bone membrane showed potential for clinical application; however, it needs to be optimized in its biocompatibility to fulfill all requirements for GBR membrane.…”
Get full text

Detection of I491F and V170F rpoB mutations associated with misdiagnosis of rifampicin resistance among patients with drug-susceptible tuberculosis treatment failure, Myanmar, 2022 by Phyu Win Ei, Mi Mi Htwe, Myat Htut Nyunt, Aye Su Mon, Zaw Myint, Wint Wint Nyunt, Su Mon Win, Sandar Aung, Wai Myat Thwe, Wah Wah Aung

“…This demonstrates a gap in current World Health Organization-endorsed algorithms for capturing all multidrug-resistant-TB strains.…”
Get full text

Risk factors for the recurrence of atrial fibrillation after catheter ablation: a meta-analysis by Gonghao Li, Yanli Zhao, Zhongxing Peng, Yunfeng Zhao

“…The strength of the link between various risk factors and AF returning after CA was evaluated using odds ratios. All statistical evaluations were conducted with RevMan5.3 software. …”
Get full text

Advances in Cell and Immune Therapies for Melanoma by Tanase Timis, Sanda Buruiana, Delia Dima, Madalina Nistor, Ximena Maria Muresan, Diana Cenariu, Adrian-Bogdan Tigu, Ciprian Tomuleasa

“…In 2020, cutaneous melanoma constituted approximately 1.3% of all cancer deaths that occurred within the European Union, thereby highlighting the necessity for effective prevention, timely diagnosis, and sustainable treatment measures, especially as a growing number of cases occur among younger patients. …”
Get full text

Freedom of expression, aspiration and gender: A cultuling in the student demonstration by Siti Nurbayani, Elly Malihah, Millary Agung Widiawaty, Moh. Dede, Bayu Iqbal Anshari, Asep Mahpudz, Erry Sukriah, Sri Wahyuni

“…Slogans were often written in all caps, including social media hashtags. Men and women demonstrators style their messages differently, but both express shared feelings of frustration and disappointment with the government and its policies. …”
Get full text

Traumatic Blunt Force Renal Injury in a Diseased Horseshoe Kidney with Successful Embolization to Treat Active Bleeding: A Case Report and Literature Review by Chonlada Krutsri, Pongsasit Singhatas, Preeda Sumpritpradit, Chunlaches Chaijareenont, Wit Viseshsindh, Tharin Thampongsa, Pattawia Choikrua

“…Blunt force injuries in patients with preexisting kidney disease account for 19% of all kidney injuries, suggesting that diseased kidneys are more vulnerable than normal kidneys. …”
Get full text

Relative Fat Mass and Physical Indices as Predictors of Gallstone Formation: Insights From Machine Learning and Logistic Regression by Deng L, Wang S, Wan D, Zhang Q, Shen W, Liu X, Zhang Y

“…Furthermore, we substantiated the link between relative fat mass (RFM) and gallstone formation by employing four logistic regression models, conducting subgroup analyses, and applying restricted cubic spline (RCS) curves.Results: The logistic regression algorithm demonstrated superior predictive capability for all risk factors associated with gallstone occurrence compared to other machine learning models. …”
Get full text

Performance of HPV E4 and p16INK4a biomarkers in predicting regression of cervical intraepithelial neoplasia grade 2 (CIN2): protocol for a historical cohort study by David Jenkins, Mark H Stoler, Anne Hammer, Torben Steiniche, Lone Kjeld Petersen, Patti E Gravitt, Rikke Kamp Damgaard, Maurits NC de Koning, Wim GV Quint, John Doorbar, Johnny Kahlert

“…Through the Danish Pathology Databank, we will collect results on all subsequent cervical biopsies. Regression will be used as the primary outcome.Ethics and dissemination The study has been approved by the Ethical Committee in Central Denmark Region (1-10-72-60-20) and registered at the Faculty of Health, Aarhus University. …”
Get full text

Short communication: Genomic prediction based on unbiased estimation of the genomic relationship matrix in pigs by M.Y. Li, L.Y. Shi, D.E. MacHugh, X.Q. Wang, J.J. Tian, L.G. Wang, Y.J. Deng, L.X. Wang, F.P. Zhao

“…Apart from the ROH method, all methods demonstrated similar levels of unbiasedness, around 1.10. …”
Get full text