Association of outpatient use of renin–angiotensin–aldosterone system blockers on outcomes of acute respiratory illness during the COVID-19 pandemic: a cohort study by Molly Moore Jeffery, Lucas Oliveira J e Silva, Fernanda Bellolio, Nathan W Cummins, Timothy M Dempsey, Vesna D Garovic, Andrew Limper

“…Objectives Evaluate the associations between patients taking ACE inhibitors and angiotensin receptor blockers (ARBs) and their clinical outcomes after an acute viral respiratory illness (AVRI) due to COVID-19.Design Retrospective cohort.Setting The USA; 2017–2018 influenza season, 2018–2019 influenza season, and 2019–2020 influenza/COVID-19 season.Participants People with hypertension (HTN) taking an ACEi, ARB or other HTN medications, and experiencing AVRI.Main outcome measures Change in hospital admission, intensive care unit (ICU) or coronary care unit (CCU), acute respiratory distress (ARD), ARD syndrome (ARDS) and all-cause mortality, comparing COVID-19 to pre-COVID-19 influenza seasons.Results The cohort included 1 059 474 episodes of AVRI (653 797 filled an ACEi or ARB, and 405 677 other HTN medications). 58.6% were women and 72.9% with age ≥65. …”
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Charge trapping in SiO2 substrate during electron beam deposition of CaF2 thin films of different thicknesses by Marina Romanova, Sergii Chertopalov, Yuri Dekhtyar, Ladislav Fekete, Ján Lančok, Michal Novotný, Petr Pokorný, Anatoli I. Popov, Hermanis Sorokins, Aleksandr Vilken

“…In a vacuum, the PE peaks and integrated PE intensity remained stable for at least 24 h for CaF2 films of all thicknesses. When exposed to air, the PE peaks persisted for several days in films 125 nm thick or thinner but relaxed within several hours in 277 nm films. …”
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Situational analysis of the quality of maternal, child, and adolescent health data in the health districts of Thiès, Mbour, Kédougou, and Saraya in Senegal by Fatoumata Binetou Diongue, Adama Faye, Cheikh Loucoubar, Ndèye Marème Sougou, Ibrahima Sy, Adama Tall, Youssoupha Ndiaye, Samba Cor Sarr

“…The average level of completeness was 0.64 (+/- 0.44) for all regions combined, with no significant difference between districts. …”
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Correlation between Serum Platelet Count and Cognitive Function in Patients with Atrial Fibrillation: A Cross-Sectional Study by Dandan Sun, Quanliang Wang, Jie Kang, Jie Zhou, Ruijuan Qian, Wenqing Wang, Haichen Wang, Qingyun Zhang

“…Cognitive function assessment and clinical and laboratory examinations were performed on all participants. After adjusting the related confounding factors, the relationship between platelet count and cognitive function was analyzed. …”
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Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…Overall 5000 Moscow inhabitants age 18 to 75 years, chosen randomly within the «the liver check up» project, have been included in prospective population study. All patients underwent following investigation: physical examination, filling of nutrition diary, CAGE and AUDIT questionnaires, taking occupational history, anthopometrical examination, US of abdominal organs, clinical and biochemical blood tests, assessment of HCVAb and HBsAg. …”
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Association between chiropractic spinal manipulative therapy and benzodiazepine prescription in patients with radicular low back pain: a retrospective cohort study using real-world... by Jeffery A Dusek, Robert James Trager, Zachary A Cupler, Kayla J DeLano, Jaime A Perez

“…Odds of receiving a benzodiazepine prescription were significantly lower in the CSMT cohort over all follow-up windows prematching and postmatching (p<0.0001). …”
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Differences in Clinicopathological Characteristics of Papillary Thyroid Carcinoma between Symptomatic and Asymptomatic Patients with Primary Hyperparathyroidism by Yuan Liu, Siyi Guo, Shaowei Sang, Jinbo Liu, Lin Qi, Bin Lv, Xiaoli Zhang

“…Compared with the symptomatic PHPT patients, the asymptomatic PHPT patients showed lower serum calcium (p<0.05), serum chlorine (p<0.05), alkaline phosphatase (p<0.05), PTH (p<0.05), and bone turnover markers (p<0.05) but higher prevalence of thyroid nodules (70.73% versus 55.24%, p<0.05) and PTC (15.44% versus 3.87%, p<0.05). All the PTC in symptomatic PHPT patients were papillary microcarcinoma limited to the thyroid, while 68.42% and 15.78% of the PTC in asymptomatic PHPT patients showed microscopic extrathyroidal extension and lymph node metastases, respectively. …”
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Sustained Impairment in Cardiopulmonary Exercise Capacity Testing in Patients after COVID-19: A Single Center Experience by Georg Evers, Arik Bernard Schulze, Irina Osiaevi, Kimon Harmening, Richard Vollenberg, Rainer Wiewrodt, Rudin Pistulli, Matthias Boentert, Phil-Robin Tepasse, Juergen R. Sindermann, Ali Yilmaz, Michael Mohr

“…Abnormal gas exchange was absent in all limited EC patients. Moreover, no patient showed signs of reduced pulmonary perfusion. …”
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Expression Profiling and Functional Implications of a Set of Zinc Finger Proteins, ZNF423, ZNF470, ZNF521, and ZNF780B, in Primary Osteoarthritic Articular Chondrocytes by Maria Mesuraca, Olimpio Galasso, Leonardo Guido, Emanuela Chiarella, Stefania Scicchitano, Renaud Vatrinet, Giovanni Morrone, Heather M. Bond, Giorgio Gasparini

“…The ZNF521 mRNA instead was abundant in all primary chondrocytes studied; the RNAi-mediated silencing of this gene significantly altered the COL2A/COL1 expression ratio, associated with the maintenance of the differentiated phenotype, in chondrocytes cultivated in alginate beads. …”
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Rotation errors in path integration are associated with Alzheimer’s disease tau pathology: a cross-sectional study by Lise Colmant, Lisa Quenon, Lara Huyghe, Adrian Ivanoiu, Thomas Gérard, Renaud Lhommel, Pauline Coppens, Yasmine Salman, Vincent Malotaux, Laurence Dricot, Lukas Kunz, Nikolai Axmacher, Philippe Lefèvre, Bernard Hanseeuw

“…The amyloid status did not influence performance among individuals with mild cognitive impairment. Among all individuals, rotation, but not distance, errors increased with the level of tau pathology in the medial temporal lobe. …”
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What are the gaps in cardiovascular risk assessment and management in primary care for Māori and Pacific people in Aotearoa New Zealand? Protocol for a systematic review by Vanessa Selak, Matire Harwood, Shanthi Ameratunga, Corina Grey, Janine Paynter, Karen Marie Brewer, Julie Winter-Smith, Sandra Hanchard

“…Two reviewers will read each full report, with one medically qualified reviewer reading all reports and two other reviewers reading half each. …”
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Varying circumstances surrounding opioid toxicity deaths across ethno-racial groups in Ontario, Canada: a population-based descriptive cross-sectional study by Tara Gomes, Mina Tadrous, Sophie A Kitchen, Frank Crichlow, Tonya J Campbell, Cynthia Damba, Colin H Johnson, Ashley Smoke

“…Accordingly, we sought to describe and compare characteristics and circumstances of opioid toxicity deaths across ethno-racial groups.Methods We conducted a population-based, descriptive cross-sectional study of all individuals who died of accidental opioid toxicity in Ontario, Canada between 1 July 2017 and 30 June 2021. …”
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Clinical Characteristics of 31 Patients with Chest Pain Variant Asthma by Mao W, Gao Y, Sun W, Li J, Wang J, Wang Z, Zhang L, Huang K

“…Here, we aim to introduce the characteristics of their symptoms, lung function and chest imaging features to arouse the attention of physicians to know better of the disease.Patients and Methods: We retrospectively analyzed thirty-one patients who had been diagnosed with CPVA based on clinical data and positive bronchial provocation tests (BPTs).Results: The mean age of all enrolled patients was forty-seven years, and females accounted for 64.5%. …”
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Optimasi Keamanan Web Server Terhadap Serangan Brute-Force Menggunakan Penetration Testing by Fahmi Fachri

“…Abstract The increase in cyber attacks and theft of sensitive data is a major topic that is often discussed today, as more and more user-oriented applications by providing all their information are deployed to the web. Penetration testing is defined as an official attempt to exploit the system with the aim of finding weaknesses in the web server and improving system security. …”
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Safety and Feasibility of Repeated Intrathecal Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells in Patients with Neurological Diseases by Kuang Pan, Lingna Deng, Peiying Chen, Qingxia Peng, Jingrui Pan, Yanfeng Wu, Yidong Wang

“…Also, we performed a systematic review of the safety of all types of intrathecal stem cells and compared our result to previous studies. …”
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Evaluation of the rainfed and irrigated conditions on biomass and essential oil yield of German chamomile (Matricaria chamomilla) in response to melatonin foliar application by Hossein Gorgini Shabankareh, Mohammad Reza Asgharipour, Ali Salehi Sardoei, Ahmad Reza Kamaliun, Hamid Mohammadi, Mansour Ghorbanpour

“…The analysis indicated that all measured traits influenced dry mass, with relative water content directly affecting dry mass and essential oil rate positively influencing both proline and dry mass. …”
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Effectiveness of an E-Nose Based on Metal Oxide Semiconductor Sensors for Coffee Quality Assessment by Yhan S. Mutz, Samara Mafra Maroum, Leticia L. G. Tessaro, Natália de Oliveira Souza, Mikaela Martins de Bem, Loyane Silvestre Alves, Luisa Pereira Figueiredo, Denes K. A. do Rosario, Patricia C. Bernardes, Cleiton Antônio Nunes

“…The performance of each model varies with the specific task, except for the LS-SVM models, which presented a perfect classification for all tasks. Therefore, combining the e-nose with distinct classification models could be used for multiple-purpose classification tasks for producers as a low-cost, rapid, and effective alternative for quality assurance.…”
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Pentraxin 3 Levels in Young Women with and without Polycystic Ovary Syndrome (PCOS) in relation to the Nutritional Status and Systemic Inflammation by Katarzyna Wyskida, Grzegorz Franik, Piotr Choręza, Natalia Pohl, Leszek Markuszewski, Aleksander Owczarek, Paweł Madej, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…While in the non-PCOS group, PTX3 levels were inversely proportional to all anthropometric parameters. Conclusions. Our results show that the decrease in PTX3 levels observed in obese is distorted in PCOS by microinflammation, and possibly, dysfunction of stroma adipose tissue and liver steatosis is reflected by enhanced insulin resistance.…”
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Efek Pemberian Suntikan Subkutan Vitamin C Terhadap Luka Insisi Dermal by Surya Darma, Menker Manjas, Deddy Saputra, Salmiah Agus, Erkadius Erkadius

“…Method:This experimental study used32 Wistar rats, divided into two group that is 16 rats as control and 16rats as experimental group. All groups underwent 2 cm long incision at the back. …”
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Implementing a Care Model for Bedridden Stroke Survivors: A Qualitative Study in Northeastern Thailand by Panpanit L, Jongudomkarn D, Doungmungkorn A, Boontoch K, Neelasmith S, Manorat M, Maneerat T

“…These findings underscored the lack of sufficient support for all groups. The study proposed the KKU Bedridden Care Model, derived from the KKU Family Health Nursing Model, to strengthen families’ and communities’ caregiving capacities. …”
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