Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery by Anil Kilinc, Nilay Tas, Melih Urkmez, Ebru Canakci, Ilker Coskun, Merve Elif Demirhan

“…Results: The study included a total of 437 cases. All patients had a mean PNI of 49.35±7.70. A one-unit increase in PNI value reduced intensive care duration by 0.495 units (p=0.049), while it reduced discharge duration by 0.101 units (p<0.001). …”
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Role and mechanism of dexmedetomidine in regulating bone metabolism in tail-suspended osteoporotic rats by GUO Yunliang, WANG Can, ZHANG Xinyu

“…Results‍　‍The animal experiments revealed that Dex treatment significantly increased the tibial trabecular bone area fraction, inhibited the decrease in bone mechanical strength, and enhanced the mineralization deposition rate and new bone formation rate of trabecular bone in the tail-suspended rats (all P<0.001). The in vitro experiments showed that Dex treatment obviously improved ALP activity and the number of ALP-positive osteoblasts in primary osteoblasts isolated from tail-suspended rats (P<0.01), and up-regulated the expression levels of osteogenic differentiation-related genes, such as Ocn, Runx2, Osx and Col1 (P<0.01). …”
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PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood by Bo Han, Qiaobo Xie, Weishi Liang, Peng Yin, Xianjun Qu, Yong Hai

“…Using weighted correlation network analysis (WGCNA), we examined all expression profile data and identified differentially expressed genes. …”
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Comparative effects of gong’s mobilization and mobilization with movement in patients with adhesive capsulitis: a randomized clinical trial by Fareeha Amjad, Hasha Asghar

“…Moreover, a medium to large effect size was also observed for all the outcomes, pain(d = 0.5), ROM (d = 0.5–2.7), SPADI(d = 0.5). …”
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Students Perceptions, Satisfactions and Challenges on Problem-Based Learning (PBL): A Survey Study Among Final Year Pharmacy Students by Engku Nuraishah Huda E. Zainudin, Fakhira Damia Khaidir, May Khin Soe, Nurul Asyiqin Yusof, Khairool Azizul Mohammad

“…Most felt comfortable participating in discussions (69%), and nearly all students were satisfied with their group members’ cooperation (95.2%). …”
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ZnO Nanoparticle-Assisted Synthesis of Thiazolo[3,2-α]Pyrimidine Analogs: Antibacterial and Antioxidant Activity, In Silico Molecular Docking, and ADMET Prediction Study by Demis Zelelew, Milkyas Endale, Yadessa Melaku, Taye B. Demissie, Japheth O. Ombito, Rajalakshmanan Eswaramoorthy

“…In the present study, a new series of nine Thiazolo[3,2-α] pyrimidine analogs were synthesized in good to excellent yields (87.9–96.9%) and improved reaction time using a ZnO nanoparticle-assisted protocol. All the synthesized compounds were characterized using a combination of physicochemical parameters, UV-visible, 1H-NMR, and 13C-NMR spectroscopic methods. …”
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Oral glucose tolerance testing as a complement to fasting plasma glucose in screening for type 2 diabetes: population-based cross-sectional analyses of 146 000 health examinations... by Patrik Wennberg, Mattias Brunström, Anna Rosén, Julia Otten, Andreas Stomby, Simon Vallin

“…The estimated NNS to prevent one case of T2D through detection and lifestyle treatment of IGT ranged from 1332 among 40-year-old men without risk factors, to 39 among 60-year-old women with all risk factors combined.Conclusions The prevalence of hyperglycaemia on OGTT is highly dependent on age, sex and risk factor burden; OGTT should be applied selectively to high-risk groups to avoid unnecessary testing in the general population.…”
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Regional Exploration and Characterisation of CO2 Storage Prospects in the Utsira-Skade Aquifer, North Viking Graben, North Sea by C. Lloyd, M. Huuse, B. J. Barrett, A. M. W. Newton

“…Subsurface CO2 storage is considered a key element of reducing anthropogenic emissions in virtually all scenarios compatible with limiting global warming to 1.5°C. …”
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Clinical Characteristics and Prognostic Factors of Posterior Segment Intraocular Foreign Body: Canadian Experience from a Tertiary University Hospital in Quebec by Jean-Philippe Rozon, Guillaume Lavertu, Mélanie Hébert, Eunice You, Serge Bourgault, Mathieu Caissie, Eric Tourville, Ali Dirani

“…A retrospective chart review was performed for all consecutive patients operated for posterior segment IOFB removal between January 2009 and December 2018. …”
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Cannabis related side effects in otolaryngology: a scoping review by Jobanjit S. Phulka, Joel W. Howlett, Amanda Hu

“…Two authors independently reviewed all studies; the senior author settled any discrepancies. …”
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Prognostic value of adjuvant chemotherapy for hormone receptor-negative T1a and T1bN0M0 breast cancer patients by Yaxiong Liu, Honghui Li, Jinsong Li, Changlong Wei, Jinsheng Zeng, Qiuhong Tian

“…The data of hormone receptor-negative T1a and T1bN0M0 breast cancer patients were extracted from the Surveillance, Epidemiology, and End Results (SEER) database from 2010 to 2015. All patients were divided into two groups according to the history of adjuvant CT namely the CT group and the no CT (No CT) group. …”
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A Study of Synergy of Combination of Eosin B with Chloroquine, Artemisinin, and Sulphadoxine-Pyrimethamine on Plasmodium falciparum In Vitro and Plasmodium berghei In Vivo by Sedigheh Sadeghi, Zarrintaj Valadkhani, Alireza Sadeghi Tafreshi, Mohammad Arjmand, Hossein Nahravanian, Farideh Vahabi, Neda Soori, Maryam Mohammadi, Masoomeh Meigooni, Zahra Zamani

“…Synergy was exhibited by isobolograms of eosin B combined with artesunate and sulphadoxine-pyrimethamine with more than 10 fold reduction of all drugs in vitro. A good combination index was obtained with artesunate at 50% inibitory concentration with 3.4 nM eosin B and 1.7 nM artesunate in contrast to 124 nM eosin B and 7.6 nM artesunate singly. …”
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Caudal vena cava isolation using ablation index‐guided radiofrequency catheter ablation (CARTO™ 3) to treat sustained atrial tachycardia in horses by Eva Buschmann, Glenn Van Steenkiste, Ingrid Vernemmen, Marie Demeyere, Stijn Schauvliege, Annelies Decloedt, Gunther vanLoon

“…Sinus rhythm was restored in all 10 horses. To date, 9‐37 months post‐ablation, none of the horses have had recurrence. …”
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Scalable information extraction from free text electronic health records using large language models by Bowen Gu, Vivian Shao, Ziqian Liao, Valentina Carducci, Santiago Romero Brufau, Jie Yang, Rishi J. Desai

“…Results LLMs outperformed the baseline pattern-matching approach, particularly for explicitly mentioned SDoH, achieving up to 40% higher Accuracymentioned. openchat_3.5 was the best-performing model, surpassing the baseline in overall accuracy across all nine SDoH aspects. The refined pipeline with prompt engineering reduced hallucinations and improved accuracy. …”
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Innovative development, microstructure and hydration characteristics of recycled brick powder-circulating fluidized bed fly ash-based earthwork subgrade backfill by Wenhuan Liu, Kaize Li, Xiaoyu Jiao, Hui Li, Honghong Cao, Yongping Qu

“…At the experimental ratio of RBP: CFBFA: coarse-grained soil = 8: 32: 60, the 28-day unconfined compressive strength (UCS), California Bearing Ratio (CBR) value, rebound modulus value, shear strength value, and compression modulus value of the sample attain their maximums, measuring 5.3 MPa, 41.9 %, 71.9 MPa, 10.5 KPa, and 15.76 MPa, respectively, all exceeding the standard values. The hydration products of cementitious materials based on RBP and CFBFA mostly consist of C-S-H gel, ettringite (AFt), and calcite. …”
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Atherogenic Index in Type 2 Diabetes and Its Relationship with Chronic Microvascular Complications by Zhen Li, Qi Huang, Li Sun, Tengfei Bao, Zhe Dai

“…Multiple logistic regression analysis showed that waist circumference, HOMA-IR, FBG, systolic blood pressure, and UA were independent risk factors for AIP (all P<0.05). The prevalence of diabetic neuropathy and metabolic syndrome was significantly higher among patients with higher AIP. …”
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Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential by I. J. Asiedu-Gyekye, T. G. Borovskaya, M. E. Poluektova, А. V. Vychuzhanina, Y. А. Shchemerovа, S. I. Kamalova, V. A. Grgoreva, P. Amoateng, K. E. Kukuia, A. A. Kwapong, L. Allotey Babington, S. K. Amponsah, B. B. N’guessan

“…Results show that a high tail DNA% was observed with methyl mesylate administration in all tissues analysed. The lowest tail DNA% value was observed in the liver (1.64 ± 0.26) and kidney (1.63 ± 0.30) during UNCP (TD) administration. …”
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Community behavior for mathematical model of coronavirus disease 2019 (COVID-19) by M. Ramli, M. Mukramati, M. Ikhwan, H. Hafnani

“…The following breakthrough is the application of the same system to the infected population, which is required to wear masks at all times during their self-isolation period. The model-generated equation system is a nonlinear system of differential equations. …”
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Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models by Kathleen Bennett, Frank Moriarty, Tom Fahey, Caitriona Cahir

“…Models were then used to evaluate the cost-effectiveness of potential interventions to reduce PIP for each of the three drug classes.Results All three PIP drugs and their AEs are associated with greater cost and fewer QALYs compared with alternatives. …”
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Comparison Of Outcomes Between Early And Delayed Reduction Of Nasal Bone Fractures by Amna Kousar, Sadia Chaudhry, Sundas Masood, Ansa Umara Akram, Amna Javaid, Adia Bushra Piracha

“…Patients who underwent early reduction (within 2 weeks of trauma) were included in Group A while those who underwent delayed reduction (more than 2 weeks) were included in Group B. They also met all inclusion and exclusion criteria requirements and these requirements were strictly adhered to to control confounders and bias. …”
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