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35061
Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells Support CD34pos Hematopoietic Stem Cell Propagation and Suppress Inflammatory Reaction
Published 2015-01-01“…We generated such iPSC-MSCs from fibroblasts and bone marrow MSCs utilizing two different reprogramming constructs. All such iPSC-MSCs exhibited the characteristics of normal bone marrow-derived (BM) MSCs. …”
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35062
Environmental sustainability of urban expansion: Implications for transport emissions, air pollution, and city growth
Published 2025-02-01“…Several traffic abatement strategies were simulated, and in all simulations a compact city consistently yields the largest reductions in CO2 emissions and NO2 levels, implying that the best abatement strategy for combating negative consequences of sprawl is to reduce sprawling. …”
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35063
The miRNA‐mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO
Published 2025-01-01“…Hub genes included RRM2, MELK, KIF11, KIF23, NCAPG, DLGAP5, BUB1B, AURKB, CCNB1, KIF20A, CCNA2, TTK, PBK, TOP2A, CDK1, MAD2L1, BIRC5, ASPM, CDCA8, and CENPF, all associated with significantly worse survival in HCC. miR‐224, miR‐24, miR‐182, miRNA‐1‐3p, miR‐30a, miR‐27a, and miR‐214 were identified as important DEmiRs with targeting more than six hub genes. …”
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35064
The Analysis of Estrogen-Degrading and Functional Metabolism Genes in Rhodococcus equi DSSKP-R-001
Published 2020-01-01“…Transcriptome analysis showed that 720 (E1), 983 (E2), and 845 (EE2) genes were significantly upregulated in the estrogen-treated group compared with the control group, and 270 differentially expressed genes (DEGs) were upregulated across all treatment groups. These DEGs included ABC transporters; estrogen-degrading genes, including those that perform initial oxidation and dehydrogenation reactions and those that further degrade the resulting substrates into small molecules; and metabolism genes that complete the intracellular transformation and utilization of estrogen metabolites through biological processes such as amino acid metabolism, lipid metabolism, carbohydrate metabolism, and the tricarboxylic acid cycle. …”
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35065
Lifestyle as Risk Factor for Infectious Causes of Death in Young Dogs: A Retrospective Study in Southern Italy (2015–2017)
Published 2020-01-01“…Ownerless dogs showed over a three-fold higher predisposition to viral coinfections than owned dogs. Above all, canine parvovirus was the most prevalent agent (77.5%), followed by canine coronavirus (31.1%) and canine adenovirus (23.9%); ownerless pups had a higher predisposition to these viruses. …”
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35066
Sequential or simultaneous-integrated boost in early-stage breast cancer patients: trade-offs between skin toxicity and risk of compromised coverage
Published 2025-01-01“…For the s-SB technique, V95 exceeded 95% under all setup errors. At 2.0° coupled with 2.0 mm, s-SIB and d-SB exhibited V95 values below 95% in 34.8% and 8.7% of cases, respectively. …”
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35067
Gestational weight gain patterns as predictors of cesarean deliveries in women diagnosed with gestational diabetes mellitus
Published 2025-01-01“…However, existing literature primarily focuses on weight gain during individual trimesters, lacking a comprehensive assessment of GWG trajectories across all three trimesters. This study aimed to investigate the impact of pre-pregnancy BMI and changes in GWG trajectories from the first to the third trimester on cesarean section in women with confirmed gestational diabetes mellitus (GDM). …”
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35068
Post COVID glaucoma service redesign utilising electronic patient triage and community optometry clinics (Fife, Scotland 2020—2022)
Published 2025-01-01“…Level three patients (1080) were retained in hospital. All outcomes were audited and analysed 24 months after the new service. …”
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35069
Facile Synthesis, Characterization, and Cytotoxic Activity of Europium-Doped Nanohydroxyapatite
Published 2016-01-01“…The toxicity effects of all samples were studied using viability assays on human fibroblasts cells (HGF-1) in vitro. …”
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35070
Screening and Characteristics of Lactic Acid Bacteria from Cheese in Yili Area
Published 2025-02-01“…The results showed that all isolated lactic acid bacteria strains (8 strains) from Yili cheese exhibited high acid and bile salt tolerance. …”
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35071
Exploring the gender difference in type 2 diabetes incidence in a Swiss cohort using latent class analysis: an intersectional approach
Published 2024-07-01“…Using the class labelled as ‘young, fit, educated men’ as reference, the risk of incident type 2 diabetes was higher in all other classes (adjusted OR values between 4.22 and 13.47). …”
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35072
Cytokines and Water Distribution in Anorexia Nervosa
Published 2021-01-01“…In the whole sample, GM-CSF, MCP-4, and IL-4 were positively, whereas IFN-γ, IL-6, and IL-10 were negatively associated with all three parameters of body water. In AN participants, we found a statistically significant negative correlation of IL-10 with ICW, ECW, and TBW. …”
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35073
Practice and factors associated with sunlight exposure of infants among mothers in Ethiopia: a systematic review and meta-analysis
Published 2025-01-01“…Results 1171 records, 13 studies were included in the meta-analysis with 5190 study participants that fulfill the inclusion criteria, and all the included studies were cross-sectional in design. …”
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35074
Anti-Inflammatory Potentials of β-Ketoester Derivatives of N-Ary Succinimides: In Vitro, In Vivo, and Molecular Docking Studies
Published 2022-01-01“…Similarly, compound D also showed excellent in vivo anti-inflammatory potential. Amongst all the compounds, D demonstrated excellent (55.92 ± 2.95%) anti-inflammatory potential at maximum tested dose (100 mg/kg) which accomplished the highest significance at 4 h following the carrageenan insertion and stayed considerable (∗∗∗P<0.001) till the 5th hour of test sample injection. …”
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35075
Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes
Published 2025-01-01“…Residual variation intolerance scores (RVIS) were calculated for all annotated autosomal genes (N = 18,168) and Gene Set Enrichment Analysis (GSEA) was used to examine patterns of constraint across ASD genes and related neurodevelopmental genes. …”
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35076
Antibiotic Resistance of Enteric Bacteria in HIV-Infected Patients at the Banka Ad-Lucem Hospital, West Region of Cameroon
Published 2019-01-01“…CD4+ T-lymphocyte count and serum hs-CRP of HIV-positive and HIV-negative patients were examined, respectively, by flux cytometry and the ELISA solid-phase direct sandwich method. Among all the participants, 39 (26.35%) were males and 109 (73.65%) were females. …”
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35077
Synthetic Retinoid Sulfarotene Selectively Inhibits Tumor‐Repopulating Cells of Intrahepatic Cholangiocarcinoma via Disrupting Cytoskeleton by P‐Selectin/PSGL1 N‐Glycosylation Bloc...
Published 2025-01-01“…It is found that although 5‐fluorouracil, cisplatin, pemigatinib, and gemcitabine all inhibit ICC‐TRCs, sulfarotene demonstrates superior efficacy. …”
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35078
Activation of the periaqueductal gray controls respiratory output through a distributed brain network
Published 2025-01-01“…We then stimulated PAG terminals in those regions to determine whether their activity can account for the observed effects of PAG stimulation.ResultsDirectly stimulating the PAG resulted in prominent changes to all recorded muscle activities and reset the breathing rhythm in either a phase-independent or phase-dependent manner. …”
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35079
Gender characteristics, social determinants, and seasonal patterns of malaria incidence, relapse, and mortality in Sistan and Baluchistan province and other province of Iran: A sys...
Published 2025-02-01“…Among the primary studies, 8 deaths were reported in two studies, all of which were men. The incidence rate of malaria relapse varied from 0.30% to 46%. …”
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35080
Patients’ and family members’ knowledge, attitudes and perceived family support for SMBG in type 2 diabetes: a fuzzy-set qualitative comparative analysis
Published 2022-12-01“…Other analyses and calculations were performed by STATA V.14.0.Results SMBG was very poor (20%), and behaviour was characterised by ‘multiple complications,’ and ‘all paths lead to the same destination’ for patients. …”
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