Colonic cytokines for severe ulcerative colitis by Ye. A. Konovich, K. Ye. Shirokikh, I. L. Khalif, M. V. Shapina

“…Overall 48 biopsy specimens of colonic mucosa obtained at resection operations in 7 patients with total form of UC were investigated. All patients underwent total colectomy for severe treatment-resistant UC. …”
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Analysis of oral cancer carcinogens in repeatedly heated cooking oils by Vidhant Krishna Nambiar, Vidya Mudliar, Inosi Salababa

“…The incidence of oral cancer in recent years has been on the rise; ninety percent of the cancers present in the oral cavity are squamous cell carcinoma with multiple major contributing lifestyle factors such well as the presence of the human papilloma virus. Not all mechanisms of carcinogenesis are fully understood and are complex. …”
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Joint Effect of Maternal Tobacco Smoking and Pregestational Diabetes on Preterm Births and Congenital Anomalies: A Population-Based Study in Northern Italy by Lucia Borsari, Carlotta Malagoli, Martha M. Werler, Kenneth J. Rothman, Marcella Malavolti, Rossella Rodolfi, Gianfranco De Girolamo, Fausto Nicolini, Marco Vinceti

“…Using hospital discharges, we identified all women with PGD delivering in Emilia-Romagna region during 2007–2010 matched 1 : 5 with parturients without diabetes. …”
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Sjögren’s Syndrome: Concerted Triggering of Sicca Conditions by Zygmunt Mackiewicz, Justyna Mażul, Ieva Narkevičiūtė, Irena Dumalakienė, Irena Butrimienė, Rita Vilienė, Indrė Stankevičienė, Diana Mieliauskaitė

“…Immunohistochemical signs of mumps virus persistence were found in the minor salivary glands of all study groups. Also, a significantly different immune response to virus infection (protein IFI16, interferons gamma and beta, dendritic cells, and receptor for natural killers) was revealed in the minor salivary glands of the study groups. …”
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Molecular Detection of Bartonella spp. in China and St. Kitts by Ke Huang, Patrick John Kelly, Jilei Zhang, Yi Yang, Weiguo Liu, Anwar Kalalah, Chengming Wang

“…While there are PCR assays that can identify individual or groups of Bartonella, there is no reliable molecular method to simultaneously detect all species while maintaining genus specificity and sensitivity. …”
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Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids by M. R. Pereira-Jorge, K. C. Andrade, F. X. Palhano-Fontes, P. R. B. Diniz, M. Sturzbecher, A. C. Santos, D. B. Araujo

“…Individual fMRI signal changes from all these areas were positively correlated with individual SRT changes. …”
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Lung Cancer with Skin and Breast Metastasis: A Case Report and Literature Review by Bikash Bhattarai, Marie Frances Schmidt, Meenakshi Ghosh, Abhisekh Sinha Ray, Saveena Manhas, Vikram Oke, Chidozie Charles Agu, Md. Rawshan Basunia, Danilo Enriquez, Joseph Quist, Catherine Bianchi, Ravi Hans, Saroj Kandel

“…Chest X-ray and chest CT reveal a right upper lobe mass and biopsies from the breast, lung, and the periumbilical mass indicate a poorly differentiated carcinoma of unclear etiology; all tumor markers are negative. The patient is male and a chronic smoker; therefore the diagnosis is made as lung carcinoma with metastases to the breast and skin. …”
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Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p by Lei Xu, Gang Zhao, Hong Zhu, Shijun Wang, Aijun Sun, Yunzeng Zou, Junbo Ge

“…Ox-LDL-mediated ICAM-1, VCAM-1, and p47phox were significantly reduced by Rosiglitazone, but all reversed after pretreating the cells with antagomiR-590-5p. …”
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Polymorphisms of Vitamin D Signaling Pathway Genes and Calcium-Sensing Receptor Gene in respect to Survival of Hemodialysis Patients: A Prospective Observational Study by Alicja E. Grzegorzewska, Monika K. Świderska, Adrianna Mostowska, Wojciech Warchoł, Paweł P. Jagodziński

“…The minor allele in GC rs2298849 was associated with all-cause mortality in univariate analysis (HR 1.330, 95% CI 1.046–1.692, P=0.020). …”
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Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department by Kelsey Ragan, Anjali Pandya, Tristan Holotnak, Katrina Koger, Neil Collins, Mark G. Swain

“…Of these, 6 patients were POC-positive (4.2%, CI 0.9–7.4%); all 6 had antibodies detected on confirmatory lab testing and 4 had detectable HCV-RNA viral loads in follow-up. …”
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Chlamydia cases in women of reproductive age, 2006–2020: an analysis of surveillance data from Southern China by Peizhen Zhao, Peng Liang, Jinshen Wang, Wenqian Xu, Shujie Huang, Cheng Wang

“…This study aimed to examine the trends and factors linked to newly diagnosed and reported chlamydia cases in women aged 15–49 in Guangdong Province from 2006 to 2020. Methods We included all newly diagnosed and reported chlamydia cases from January 1, 2006, to December 31, 2020. …”
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Effects of Fasudil on Patients with Pulmonary Hypertension Associated with Left Ventricular Heart Failure with Preserved Ejection Fraction: A Prospective Intervention Study by Xiang Zhang, Xueming Zhang, Saihua Wang, Jun Luo, Zhihong Zhao, Changzhu Zheng, Jieyan Shen

“…Patients were diagnosed with passive pulmonary hypertension (PPH) or reactive pulmonary hypertension (RPH) by right heart catheterization and all receiving Rho kinase inhibitor fasudil for 2 weeks. …”
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A Novel Dry Model for Practicable Sphincterotomy and Precut Needle Knife Sphincterotomy by Akio Katanuma, Takao Itoi, Junko Umeda, Ryosuke Tonozuka, Shuntaro Mukai, Kei Yane, Toshifumi Kin, Kazuaki Matsumoto, Tomoaki Matsumori, Katsushige Gon, Ryo Takaki, Akiko Tomonari

“…ES was successful in 33 out of 34 attempts (97%) whereas NKP was successful in all 7 attempts (100%). Based on the results of the questionnaire survey, the median score for realism was 7 (range: 2–9) for ES and 8 for NKP on a scale of 1 to 10. …”
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The use of strong analgesics for prehospital pain management in children in the region of Southern Denmark: a register-based study by Josefine Tvede Colding-Jørgensen, Gina Maj Graven Brandstrup, Vibe Maria Laden Nielsen, Josefine Gradman, Line Anker Bang Thybo, Peter Martin Hansen, Daniel Wittrock, Stig Nikolaj Fasmer Blomberg, Helle Collatz Christensen, Søren Mikkelsen

“…In one in seventeen of all prehospital contacts with children, fentanyl, alfentanil, morphine and/or s-ketamine was administered. …”
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Environmental risk factors for self-harm during imprisonment: A pilot prospective cohort study. by Thomas Stephenson, Imogen Harris, Charlotte Armstrong, Seena Fazel, Roxanna Short, Nigel Blackwood

“…<h4>Methods</h4>A random sample of all prisoners (N = 149) starting a period of imprisonment at the study prison took part in a clinical research interview, which assessed a range of known risk factors for self-harm in prison. …”
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CT Texture Analysis in Breast Cancer Patients Undergoing CT-Guided Bone Biopsy: Correlations With Histopathology by Silvio Wermelskirchen, Jakob Leonhardi, Anne-Kathrin Höhn, Georg Osterhoff, Nikolas Schopow, Susanne Briest, Timm Denecke, Hans-Jonas Meyer

“…Methods: The present study included a total of 66 patients. All patients proceeded to undergo a CT-guided percutaneous bone biopsy, using an 11-gauge coaxial needle. …”
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Secular trends of epidemiologic patterns of chronic kidney disease over three decades: an updated analysis of the Global Burden of Disease Study 2019 by Jing Liu, Xue Li, Yongping Liu, Xiaodong Sun, Xiaojin Feng, Ningning Hou, Zhenna Chen

“…The age-standardised death rate (ASDR) of CKD, among all causes, increased from 15th in 1990 to 10th in 2019. …”
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Prevalence of childhood mental disorders in high-income countries: a systematic review and meta-analysis to inform policymaking by Charlotte Waddell, Christine Schwartz, Jenny Lou Barican, Donna Yung, Yufei Zheng, Katholiki Georgiades

“…We conducted meta-analyses using a random effects logistic model (using R metafor package).Findings Fourteen studies in 11 countries met inclusion criteria, published from 2003 to 2020 with a pooled sample of 61 545 children aged 4–18 years, including eight reporting service use. (All data were collected pre-COVID-19.) Overall prevalence of any childhood mental disorder was 12.7% (95% CI 10.1% to 15.9%; I2=99.1%). …”
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Study on seismic performance of high-strength steel earthquake-resilient beam-column joint with double damage elements by Hongchao Guo, Dongdong Zheng, Jing Lu, Xudong Zhou, Wenqi Wang, Yunhe Liu

“…It is recommended to ensure that the stability coefficient of the flange cover plate is not less than 0.967; Considering all factors, it is recommended that hs be taken as 0.2 times the width of the flange cover plate, lc be taken as 1.3 times the height of the beam, and αa taken as 50°. …”

Predictors of non-response to successive waves of surveys in the Japan Environment and Children’s Study during the 3-year postpartum period: a longitudinal cohort study by Mika Kigawa, Akiko Tsuchida, Tomomi Tanaka, Kei Hamazaki, Yuichi Adachi, Hidekuni Inadera, Kenta Matsumura, Haruka Kasamatsu

“…The strength of the impact of related factors and the prediction of response status were examined and compared using binominal logistic regression analysis.Results For all six follow-up questionnaire surveys, higher maternal age was strongly associated with providing a response. …”
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