Evaluation of Treatment Patterns and Maintenance Dose Titration Among Patients With Crohn’s Disease Initiating Biologics With 3 Years of Follow-Up by Ruizhi Zhao, Zhijie Ding, Parul Gupta, Laurence Gozalo, Robert Bruette, Victor M. Johnson, Keshia Maughn, Yihang Liu, Sumesh Kachroo

“…**Methods:** This retrospective observational study was conducted using the STATinMED RWD Insights all-payer medical and pharmacy data. Adult patients with at least 1 CD medical claim and at least 1 medical/pharmacy claim for a biologic (adalimumab \[ADA\], certolizumab pegol (CZP), infliximab \[IFX\] and its biosimilar products \[IFX-BS\], ustekinumab \[UST\], and vedolizumab \[VDZ\]) between September 2016 and October 2018 were identified. …”
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Dried and Tested: Inoculation Method Impacts Low-Moisture Food Persistent Bacterial Populations by Manita Adhikari, Kavita Patil, Jennifer C. Acuff

“…Salmonella LMF PBP reductions were lower for the lawn-prepared cultures (0.3–2.7 log CFU/cm2) compared to broth-based cultures (1.0–5.1 log CFU/cm2) for all food matrices. Salmonella in LMF PBP with SiO2 (2.7–5.1 log CFU/cm2) reduced significantly more than in other food matrices (0.7–2.2 log CFU/cm2) and Sal without a matrix (0.3–1.5 log CFU/cm2) for both culturing methods.…”
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Molecular Epidemiology and Genetic Evolution of Porcine Reproductive and Respiratory Syndrome Virus in Northern China During 2021–2023 by Na Yuan, Zuofeng Yang, Fengxia Lv, Lina Dou, Xiangqing Li, Baokai Zhao, Shishan Dong

“…In this study, 12,299 clinical samples were collected from northern China during 2021–2023 to investigate the molecular epidemiological characteristics and genetic evolution of PRRSV. All samples were screened using qRT-PCR and further analyzed through <i>ORF5</i> gene and whole-genome sequencing. …”
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Effect of Activated Platelet-Rich Plasma on Chondrogenic Differentiation of Rabbit Bone Marrow-Derived Mesenchymal Stem Cells by Zhen Wang, Zheng Wang, Bin Zhang, Qinghua Zhao, Yubao Liu, Wei Qi

“…The proliferation of BMSCs was enhanced in all groups, and 10% PRP revealed more significant outcome than the others from day 5. …”
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Proinflammatory Effects of Diesel Exhaust Nanoparticles on Scleroderma Skin Cells by A. Mastrofrancesco, M. Alfè, E. Rosato, V. Gargiulo, C. Beatrice, G. Di Blasio, B. Zhang, D. S. Su, M. Picardo, S. Fiorito

“…Moreover, the mRNA gene expression of all MMPs, collagen types, and VEGF genes was significantly higher in untreated SSc fibroblasts versus controls. …”
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Real-World Characterization of Toxicities and Medication Management in Recipients of CAR T-Cell Therapy for Relapsed or Refractory Large B-Cell Lymphoma in Nova Scotia, Canada by Jenna Shaw, Mahmoud Elsawy, Rachel Nielsen, Amye Michelle Harrigan, Tara T. DiCostanzo, Laura V. Minard

“…Twenty-seven patients received axicabtagene ciloleucel. All patients experienced CRS (7.4% grade ≥ 3), and 55.6% developed ICANS (25.9% grade ≥ 3). …”
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Midwives’ knowledge and perspectives on neonatal resuscitation and survival before and after Helping Babies Breathe training: a qualitative study in Uganda by Anna Bergstrom, Josaphat Byamugisha, Susanna Myrnerts Höök, Marielle Abrahamsson, Sarah Namusoko

“…A data-driven inductive content analysis approach was used for the analysis.Setting The high-risk labour ward and theatre at a National Referral Hospital, Uganda.Participants 45 clinically active midwives were enrolled; all had recently completed the HBB training programme.Intervention Semistructured individual interviews (n=2) and focus group discussions (n=43, distributed across seven groups) were held from 26 April to 4 May 2018. …”
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A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2– Metastatic Breast Cancer by Elizabeth J. Anderson, Lea E. Mollon, Joni L. Dean, Terri L. Warholak, Ayal Aizer, Emma A. Platt, Derek H. Tang, Lisa E. Davis

“…Prevalence of this mutation and utility of test methodologies likely warrants PIK3CA mutation testing in all patients with this breast cancer subtype via definitive assessment of PIK3CA mutational status.…”
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Therapeutic Approaches in Mitochondrial Dysfunction, Inflammation, and Autophagy in Uremic Cachexia: Role of Aerobic Exercise by Yumei Zhang, Yuqing Liu, Xiao Bi, Chun Hu, Feng Ding, Wei Ding

“…We found that CKD mice exhibited higher BUN and creatinine levels and more severe glomerulosclerosis in the glomeruli and renal tubulointerstitial fibrosis, relative to the Sham group; all these effects were relieved by aerobic exercise. …”
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Diversity and Conservation Status of Large Mammals in Ghamot National Park, Azad Jammu and Kashmir, Pakistan by Muhammad Jahangeer, Siddique Muhammad, Muhammad Shakeel, Mir Muhammad Saleem, Ali Usman, Hussain Abid

“… We assessed the richness, diversity, composition of the large mammal community in Ghamot National Park (GNP), Neelum valley Azad Jammu and Kashmir, Pakistan, and how these characteristics differed between four habitat types: forest, riparian zone, scrubland, and wetland, as well as between seasons. Across all locales with 66 line transect surveys (53km), indirect observation had the highest sampling (n=131; 76.60%) while direct observation had the lowest (n=40; 23.39). …”
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The role of L.M. Karakhan in the Chinese policy of the Soviet Union (1923–1926) by I. N. Sotnikova

“…The figure of L.M. Karakhan is all the more remarkable because, being one of the architects of the USSR’s foreign policy towards China, he himself has not received much attention in either Soviet or Russian historiography. …”
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Evaluation of a pilot family planning educational seminar and subsequent attitudes towards family planning among Muslim communities in Tanzania. by Alexandra A Cordeiro, Hajirah Gumanneh, Aneth Nzali, Valencia J Lambert, Amina Yussuph, Albert Kihunrwa, Yassin Mchondo, Ramadhan Mtita, Hidaya Yahaya, Samuel E Kalluvya, Joyce Wamoyi, Mehrunisha Suleman, Jennifer A Downs, Agrey H Mwakisole

“…Others described having taught their communities about FP and described the positive impact the seminar had for enhancing couple communication and enabling FP uptake for those desiring to use it. Almost all participants recommended that the seminars return to their community more frequently and indicated the importance of allowing discussion time for men and women separately during part of the seminar. …”
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Designing an intervention to improve cognitive evaluations in primary care by Kyra S. O’Brien, Kristin Harkins, MaryAnne Peifer, Melanie Kleid, Cameron Coykendall, Judy Shea, Jason Karlawish, Robert E. Burke

“…For some patients, early detection of cognitive impairment enables access to disease-modifying therapies. For all patients, it allows access to psychosocial supports. …”
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Hubungan Status Gizi dengan Perkembangan Psikomotorik Balita di Wilayah Kerja Puskesmas Lapai Padang Tahun 2014 by Hamdini Humaira, Yusri Dianne Jurnalis, Edison .

“…</em></p><p><strong><em>Keywords: </em></strong><em>nutritional status, psychomotor development</em></p></div><em><br clear="all" /> </em>…”
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Correction of CAMS PM₁₀ Reanalysis Improves AI-Based Dust Event Forecast by Ron Sarafian, Sagi Nathan, Dori Nissenbaum, Salman Khan, Yinon Rudich

“…Comparing the network’s performance when trained on both original and bias-corrected CAMS PM₁₀ fields, we show that the correction improves AI-based forecasting performance across all metrics.…”
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Exploring nutritional risks of the specific carbohydrate diet: food and nutrient intake in children with juvenile idiopathic arthritis by Naima Hagström, Afsaneh Koochek, Eva Warensjö Lemming, Anders Öman, Henrik Arnell, Lillemor Berntson

“…In a secondary analysis, food and nutrient intakes from three-day dietary records of ten children, following a four-week SCD intervention, were evaluated against the Nordic Nutrition Recommendations 2023 and Riksmaten Adolescents data (RMA) (n = 1282). All children following the SCD met the recommended minimum intake of fruit and vegetables of 500g/day, a stark contrast to the 6% in RMA. …”
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A clinical study on the efficacy and safety of poly-herbal formulation in managing functional dyspepsia by Debasish Hota, Anand Srinivasan, Manas Kumar Panigrahi, Snigdha Suman Dalua, Poorva Tiwari, Ramachandran Valavan

“…The primary objective was to assess the improvement in symptoms using various questionnaires at All India Institute of Medical Science Bhubaneswar, including the Reflux Disease Questionnaire, Short-Form Leeds Dyspepsia Questionnaire, GERD-Health Related Quality of Life Questionnaire, visual analogue scale (VAS) for pain, and Investigator's Symptomatic Assessment. …”
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Simultaneous Determination of Cr, As, Se, and Other Trace Metal Elements in Seawater by ICP-MS with Hybrid Simultaneous Preconcentration Combining Iron Hydroxide Coprecipitation an... by Akihide Itoh, Masato Ono, Kota Suzuki, Takumi Yasuda, Kazuhiko Nakano, Kimika Kaneshima, Kazuho Inaba

“…Nevertheless, the present method would have possibility to develop as the analytical method to determine comprehensively most metal elements in all standard and guideline values in quality standard in environmental water in Japan, that is, most toxic metal elements in environmental water.…”
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Clinical profile and outcomes analysis of HIV infection by Ashwant Kumar, Yoganathan Chidambaram, Clement J. Dhas, Nekkanti Abilash, Murali Alagesan

“…Renal tubular necrosis (5%) was the most common adverse effect of HAART, while 1% developed immune reconstitution inflammatory syndrome. Conclusions All adult HIV patients should be screened for side effects associated with HAART medi­cations in addition to typical HIV presentation.…”
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How climate change is shaping young people’s health: a participatory, youth co-led study from Bangladesh, Guatemala and Nigeria by Jessie Pinchoff, Karen Austrian, Eno-Obong Etetim, Damilola Babatunde, Eleanor Blomstrom, Sigma Ainul, Toyin Olamide Akomolafe, Brian Medina Carranza, Angel Del Valle

“…Another common theme was anxiety about climate change, its effects on economic and food insecurity in communities and feeling hopeless, lacking agency and not feeling supported by local institutions, all linked with worse mental health.Conclusion Our results summarise how AYP perceive climate change is affecting their physical and mental health, finding similarities and differences across these three settings. …”
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