Impact of multimorbidity and complex multimorbidity on mortality among older Australians aged 45 years and over: a large population-based record linkage study by Alamgir Kabir, An Tran, Sameera Ansari, Damian P Conway, Margo Barr

“…The relative impact of MM and CMM on mortality decreased as age increased.Conclusion MM and CMM were common in older Australian adults; and MM was a better predictor of all-cause mortality risk than CMM. Higher mortality risk in those aged 45–59 years indicates tailored, person-centred integrated care interventions and better access to holistic healthcare are needed for this age group.…”
Get full text

Sources and Trends of CO, O₃, and Aerosols at the Mount Bachelor Observatory (2004–2022) by Noah Bernays, Jakob Johnson, Daniel Jaffe

“…., and a strong negative trend in the springtime values at all percentiles (1.6% yr⁻¹ for 50th percentile). …”
Get full text

How defensive medicine is defined in European medical literature: a systematic review by Nathalie Baungaard, Elisabeth Assing Hvidt, Helle Gerbild, Merethe Kirstine Andersen, Jesper Lykkegaard, Pia Ladeby Skovvang

“…The objectives of this systematic review were to explore the definition of the term ‘defensive medicine’ in European original medical literature and to identify the motives stated therein.Design Systematic review.Data sources PubMed, Embase and Cochrane, 3 February 2020, with an updated search on 6 March 2021.Methods Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, we reviewed all European original peer-reviewed studies fully or partially investigating ‘defensive medicine’.Results We identified a total of 50 studies. …”
Get full text

Eculizumab treatment for Chinese patients with hemolytic paroxysmal nocturnal hemoglobinuria (PNH): efficacy and safety – a single-center study by Leyu Wang, Ziwei Liu, Chen Yang, Miao Chen, Bing Han

“…During the follow-up period, Lactate Dehydrogenase (LDH) levels were lower than those at baseline (<0.05) at all observation points. The patients showed a significant reduction in creatinine levels from baseline (P = 0.022 and P = 0.039, respectively) at 1 and 3 months. …”
Get full text

Interventional factors influencing natural killer cell immunity in colorectal cancer: a systematic review by Wai Sinn Soh, Grace L. Burns, Tharindu Senanayake, Raquel Cameron, Kerith Duncanson, Guy D. Eslick, Sharmila S. Prasad, Stephen R. Smith, Simon Keely

“…This effect was observed across all examined medications, including fentanyl, morphine, propofol and oxycodone. …”
Get full text

DIGITISATION OF LEGAL ALGORITHMS TO PREVENT PUBLIC PROCUREMENT CORRUPTION by Oleksii Makarenkov

“…It was emphasised that the entity responsible for the oversight of the integrity and legality of all public procurement participants, or a complainant, must possess the capacity to gather evidence in such cases. …”
Get full text

Dipeptidyl Peptidase 4 Activity Is Related to Body Composition, Measures of Adiposity, and Insulin Resistance in Subjects with Excessive Adiposity and Different Degrees of Glucose... by Wellington S. Silva Júnior, Maria das Graças C. Souza, José Firmino Nogueira Neto, Eliete Bouskela, Luiz Guilherme Kraemer-Aguiar

“…At fasting, pooled analysis showed it was positively correlated with measures of central adiposity, such as WC (P=0.011) and WHR (P=0.009), and with all measures of IR, but inversely related to indexes of general adiposity, such as fat mass percentage (P=0.014) and BAI (P=0.0003). …”
Get full text

Tectonometamorphic evolution of a subduction plate interface at the base of the Mirdita Ophiolite (Bajram Curri, northeastern Albania) by Madeline Richter, Kilian Pollok, Kujtim Onuzi, Kamil Ustaszewski

“…Shear sense indicators in calcschists of the metamorphic sole show top to the west transport of the overriding units. All metamorphic sole lithologies were overprinted at lower greenschist-facies conditions, reflecting their exhumation from intraoceanic subduction. …”
Get full text

Trends in vegetation cover changes in Bonny area of the Niger Delta by A Adoki

“…The area covered by mangrove forest consistently declined over all the epochs while the reverse was the case with respect to the area covered by sparse vegetation. …”
Get full text

Epidemiology, Prognosis, and Evolution of Management of Septic Shock in a French Intensive Care Unit: A Five Years Survey by Nicolas Boussekey, Juliette Cantrel, Lise Dorchin Debrabant, Joachim Langlois, Patick Devos, Agnes Meybeck, Arnaud Chiche, Hugues Georges, Olivier Leroy

“…Morbidity improved with time (diminution of septic shock complications, increase of the number of days alive free from mechanical ventilation and vasopressors on day 28), concomitant to an evolution of the management (earlier institution of all replacement and medical therapies and more initial volume expansion). …”
Get full text

Esophageal Impedance-pH Monitoring and Pharyngeal pH Monitoring in the Diagnosis of Extraesophageal Reflux in Children by Anna Plocek, Beata Gębora-Kowalska, Jakub Białek, Wojciech Fendler, Ewa Toporowska-Kowalska

“…MII-pH and Dx-pH were conducted concurrently in all patients. A total of 1228 reflux episodes were recorded by MII-pH. …”
Get full text

Expert-Performed Endotracheal Intubation-Related Complications in Trauma Patients: Incidence, Possible Risk Factors, and Outcomes in the Prehospital Setting and Emergency Departmen... by Yuko Ono, Takeyasu Kakamu, Hiroaki Kikuchi, Yusuke Mori, Yui Watanabe, Kazuaki Shinohara

“…This single-center retrospective observational study included all injured patients who underwent anesthesiologist-performed ETI from 2007 to 2017. …”
Get full text

Breg Cells in Celiac Disease Isolated or Associated to Hashimoto’s Thyroiditis by Maria Giulia Santaguida, Ilenia Gatto, Giorgio Mangino, Camilla Virili, Ilaria Stramazzo, Poupak Fallahi, Alessandro Antonelli, Patrizia Gargiulo, Giovanna Romeo, Marco Centanni

“…Following CpG oligodeoxynucleotide stimulation, IL-10+ CD24hiCD38hi Breg cells were similar in all groups of patients, despite these cells would have been higher in CD patients. …”
Get full text

Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case–control study by Elif Baris, Izel Topaloglu, Elif Akalin, Emre Hamurtekin, Seray Kabaran, Ayse Gelal, Reyhan Ucku, Mualla Aylin Arici

“…Serum choline, leptin and (interleukin)IL-6 levels were measured from fasting blood samples of volunteers with enzyme-linked immunosorbent assays (ELISA). Results All FMS patients (n = 38) and healthy volunteers (n = 38) were female. …”
Get full text

Development, in vitro and ex vivo characterization of lamotrigine-loaded bovine serum albumin nanoparticles using QbD approach by Maryana Salamah, Bence Sipos, Zsuzsanna Schelz, István Zupkó, Ágnes Kiricsi, Ágnes Szalenkó-Tőkés, László Rovó, Gábor Katona, György Tibor Balogh, Ildikó Csóka

“…The results of the blood-brain barrier parallel artificial membrane permeability assay (BBB-PAMPA) showed an increase in the permeability of LAM through the BBB with NP-GLUC-9 and an increase in flux with all selected formulations. The ex vivo study showed that LAM diffusion from the selected formulations through the human nasal mucosa was higher than in case of initial LAM. …”
Get full text

Analysis of Metal Contents in Portland Type V and MTA-Based Cements by Maura Cristiane Gonçales Orçati Dorileo, Matheus Coelho Bandeca, Fábio Luis Miranda Pedro, Luiz Evaristo Ricci Volpato, Orlando Aguirre Guedes, Ricardo Dalla Villa, Mateus Rodrigues Tonetto, Alvaro Henrique Borges

“…Type V PC presented the greatest concentration levels of arsenic, chromium, copper, iron, lead, and manganese (P<0.05). Bismuth was found in all cements, and the lowest concentration levels were observed in Portland cements, while the highest were observed in ProRoot MTA. …”
Get full text

Suicidality and Illness Course Worsening in a Male Patient with Bipolar Disorder during Tamoxifen Treatment for ER+/HER2+ Breast Cancer by Claudia Carmassi, Francesco Pardini, Valerio Dell’Oste, Annalisa Cordone, Virginia Pedrinelli, Marly Simoncini, Liliana Dell’Osso

“…Psychiatric assessments included the Montgomery-Asberg Depression Rating Scale (MADRS), the Hamilton Depression Scale (HAM-D), the Columbia Suicide Severity Rating Scale (C-SSRS), and the Quality of Life Enjoyment and Satisfaction Questionnaire Short Form (Q-LES-Q-SF). All questionnaires were administered at the time of the second hospitalization and in a one-year follow-up. …”
Get full text

THE TRANSFORMATION PERIODS IN THE RUSSIAN-TURKISH RELATIONS (1991-2016) by D. G. Bdoyan

“…After this, the Russian-Turkish relations deteriorated to their lowest point, practically in all spheres. Since August 2016 the relations have been gradually improving. …”
Get full text

Patient-Accessible Electronic Health Records and Information Practices in Mental Health Care Contexts: Scoping Review by Timothy Kariotis, Megan Prictor, Kathleen Gray, Shanton Chang

“…A comprehensive search of electronic databases was conducted for original empirical studies that described the use of PAEHRs or associated systems in mental health care contexts. One author reviewed all full texts, with 3 other authors reviewing a subset of studies. …”
Get full text

The Effect of Innovative Technology Benefits and E-Commerce Using Motivations on Customer Experience and Customer Information by Zahra Bigdelou, Alireza Rousta, Farzad Asayesh

“…The statistical population of the study was all customers of Digi Kala Co. Due to the uncertainty of these customers, based on Cochran's formula at a level of 5% error, 384 people were selected as a sample. …”
Get full text