Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study by Jennifer Moore, Alicia Aylott, Wen-Hung Chen, Jerzy Daniluk, Ian A. Hawes, Sergio Parra, Prosenjit Sarkar, Yasmin Sanchez-Pearson, Megan Turner, Amanda Peppercorn, Andrew Skingsley

“…Injection site reactions were reported by all participants as ‘not at all’ or ‘a little’ bothersome. …”
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Protein-DNA interactions: statistical analysis of interatomic contacts in major and minor grooves by A. A. Anashkina, E. N. Kuznetsov, A. V.  Batianovskii, L. A. Uroshlev, V. G. Tumanyan, N. G. Esipova

“…The contact with the atoms of the nucleic bases emerging into the grooves of DNA is 17.0 % for a major groove and 10.1 % for all atomic contacts for a minor groove. Totally, the interaction between protein atoms and nucleic base atoms accounts for 27.1 % of all contacts. …”
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Microsatellite loci variability in apple cultivars developed at VIR by A. V. Shlyavas, A. A. Trifonova, I. S. Chepinoga, A. S. Sidnin, K. V. Boris

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Impacts of Climatic Change on Reference Crop Evapotranspiration across Different Climatic Zones of Ningxia at Multi-Time Scales from 1957 to 2018 by Ziyang Zhao, Hongrui Wang, Cheng Wang, Wangcheng Li, Hao Chen, Shuxin Gong

“…The results showed that the Tmean (daily mean air temperature), Tmax (daily maximum air temperature), and Tmin (daily minimum air temperature) all had increased significantly over the past 62 years, whilst RH (relative humidity), U2 (wind speed at 2 m height), and SD (sunshine duration) had significantly decreasing trends across all climatic zones. …”
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Isolation and Characterization of an Adult Stem Cell Population from Human Epidural Fat by Nedaa Al-Jezani, Roger Cho, Anand O. Masson, Brian Lenehan, Roman Krawetz, Frank G. Lyons

“…HEF cells demonstrated MSC surface marker expression. All patient cell lines contracted collagen gels. …”
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The Role of Positron Emission Tomography Imaging in Breast Implant Illness by Siham Azahaf, MD, Karlinde A. Spit, MD, Christel J.M. de Blok, MD, PhD, Peter Bult, MD, PhD, Prabath W.B. Nanayakkara, MD, PhD, FRCP

“…Before PET imaging, silicone deposits were demonstrated in all 18 cases using ultrasound or magnetic resonance imaging. …”
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Impact of the Seeding Method on Physiological, Agronomic, and Biochemical Performance of Sesame (Sesamum indicum L.) Varieties Grown in Burkina Faso by Badiel Badoua, Kihindo Adama Pascal, Yao Koffi Bertin, Nana Rasmata, Ouedraogo Razacswendé Fanta, Dondasse Edmond, Tamini Zoumbiessé

“…Na accumulation in leaves was statistically equal for all varieties in both broadcast and row seeding. …”
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Biomechanical simulation of bed turning post-acetabular fracture fixation by Haiyang Wu, Zaijie Sun, Qixiao Shen, Xuejian Wu, Cheng Li, Xianhua Cai

“…Additionally, the medial displacement of the quadrilateral plate was significantly reduced in Group B compared to Group C at all measured time points (P < 0.05). And Group C exhibited significantly higher maximum tensile and compressive strain than Group B (all P < 0.05). …”
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Deep Learning Algorithms for Detection and Classification of Gastrointestinal Diseases by Mosleh Hmoud Al-Adhaileh, Ebrahim Mohammed Senan, Waselallah Alsaade, Theyazn H. H Aldhyani, Nizar Alsharif, Ahmed Abdullah Alqarni, M. Irfan Uddin, Mohammed Y. Alzahrani, Elham D. Alzain, Mukti E. Jadhav

“…Medical video endoscopy generates many images, so doctors need considerable time to follow up all the images. This creates a challenge for manual diagnosis and has encouraged investigations into computer-aided techniques to diagnose all the generated images in a short period and with high accuracy. …”
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Efficacy Of Vocal Cord Medialization by Injection Thyroplasty Using Liquid Paraffin In Relieving Hoarseness Of Voice In Idiopathic And Traumatic Unilateral Vocal Cord Paralysis by Muhammad Saleem, Muhammad Sarim Khan, Ashar Alamgir, Muhammad Hamza Rana, Hafiz Sajjad Hyder, Syeda Jamila Ali

“…All the procedures were done under local anaesthesia. …”
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Neuropsychological morbidity in the First Seizure Clinic: Prominent mood symptoms and memory issues in epilepsy by Remy Pugh, David N. Vaughan, Graeme D. Jackson, Jennie Ponsford, Chris Tailby

“…Clinically significant depressive symptoms were similarly prevalent in all patient groups, with one in three at risk for Major Depressive Disorder. …”
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Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria by Kim Anh Nguyen, Nasheeta Peer, Anniza de Villiers, Barbara Mukasa, Tandi E. Matsha, Edward J. Mills, Andre Pascal Kengne

“…Prevalence was always higher in women than in men (all p<0.001), in participants with longer duration of diagnosed HIV (all p≤0.003), and in ART users not receiving 1st-line regimens (all p≤0.039). …”
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Recovery of the Intestinal Microbiota Metabolic Activity in Patients with Bronchial Asthma by O. Yu. Zolnikova, N. D. Potskhverashvili, N. I. Kokina

“…All patients demonstrated normalisation of the SCFA spectrum and anaerobic index. …”
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Long-Term Observations of Thickness Changes of Each Retinal Layer following Macular Hole Surgery by Atsushi Tada, Shigeki Machida, Yuji Hara, Satoshi Ebihara, Masahiko Ishizuka, Mana Gonmori

“…A single surgeon operated on all patients, and all were followed for at least 24 months postoperatively. …”
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Smartphone Delivery of Mobile HIV Risk Reduction Education by Karran A. Phillips, David H. Epstein, Mustapha Mezghanni, Massoud Vahabzadeh, David Reamer, Daniel Agage, Kenzie L. Preston

“…All 3 videos met our a priori criteria for acceptability “as is” in the population: they achieved median scores of ≤2.5 on a 5-point Likert scale; ≤20% of the individuals gave them the most negative rating on the scale; a majority of the individuals stated that they would not prefer other formats over video-based smartphone-delivered one (all P<0.05). …”
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Psychological interventions for inflammatory bowel disease: a systematic review and component network meta-analysis protocol by Antje Timmer, Gerta Rücker, Natalia Tiles-Sar, Johanna Neuser, Dominik de Sordi, Anne Baltes, Jan Preiss, Gabriele Moser

“…Two authors will independently screen all references based on titles and abstracts. For data extraction, standard forms are developed and tested before extraction. …”
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Clinical Efficacy and Safety of Trans-Sacral Epiduroscopic Laser Decompression Compared to Percutaneous Epidural Neuroplasty by Bong Ju Moon, Seong Yi, Yoon Ha, Keung Nyun Kim, Do Heum Yoon, Dong Ah Shin

“…However, the VAS, ODI, and SF-12 scores improved significantly after the procedures by postoperative week 24 in each group (all P<0.05). Furthermore, improvements of VAS, ODI, SF-12, and success rate of Macnab criteria in the SELD group were better than those in the PEN group (all P<0.05). …”
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Altered Hemodynamics Associated with Pathogenesis of the Vertebral Artery Dissecting Aneurysms by Akira Kurata, Sachio Suzuki, Kazuhisa Iwamoto, Kuniaki Nakahara, Katsutoshi Abe, Madoka Inukai, June Niki, Makoto Sasaki, Kiyotaka Fujii, Shingo Konno, Shinichi Kan, Kazuaki Fukasaku

“…Turbulent blood flow was recognized in all of these patients with retrograde inflow. Conclusions. …”
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Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study by Seyed Moayed Alavian, Mohammad Tasavon Gholamhoseini, Heidar Sharafi, Helena HL Borba, Asma Sabermahani, Behzad Hajarizadeh

“…A decision tree was developed for HCV treatment, assuming four scenarios, including scenario 1: genotyping, sofosbuvir/ledipasvir (SOF/LDV) for genotype 1, and sofosbuvir/daclatasvir (SOF/DCV) for genotype 3; scenario 2: genotyping, SOF/LDV for genotype 1, and sofosbuvir/velpatasvir (SOF/VEL) for genotype 3; scenario 3: no genotyping and SOF/DCV for all; and scenario 4: no genotyping and SOF/VEL for all. …”
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Association of Pneumatosis Intestinalis With Surgical Outcomes and Mortality: A Matched, Retrospective Cohort Study and Literature Review by Kyle D. Klingbeil, MD, MS, Hila Zelicha, PhD, RD, Yijun Chen, MD, Douglas S. Bell, MD, Edward H. Livingston, MD, FACS, AGAF

“…Of those who undergo surgery, nearly all have indications for laparotomy exclusive of PI. …”
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