Association of thoracic aortic calcium with incident cardiovascular disease and all-cause mortality across the spectrum of coronary artery calcium burden by Alexander C. Razavi, Omar Dzaye, Miguel Cainzos-Achirica, Zeina Dardari, Marly Van Assen, Arshed A. Quyyumi, Khurram Nasir, J. Jeffrey Carr, Matthew J. Budoff, Roger S. Blumenthal, Paolo Raggi, Carlo N. De Cecco, Laurence S. Sperling, Michael J. Blaha, Seamus P. Whelton

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Vascularized Iliac Crest Bone Graft for the Reconstruction of Anterior Vertebral Corpus Defects: A Literature Review and Cadaveric Feasibility Study by Jonathan L. Jeger, MB BCh, Casey J. Martinez, BS, Maria Shvedova, MD, Alec Simoni, BS, Alanna Rebecca, MD, Sebastian Winocour, MD, Alexander E. Ropper, MD, Michael Bohl, MD, William J. Casey, III, MD, Maziyar Kalani, MD, Edward M. Reece, MD, MS

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Diversity in the medical research ecosystem: a descriptive scientometric analysis of over 49 000 studies and 150 000 authors published in high-impact medical journals between 2007... by Leo Anthony Celi, Jonathan Shaffer, Marie-Laure Charpignon, Liam G McCoy, Luis Filipe Nakayama, Jack Gallifant, Urvish Jain, Joao Matos, Pia Gabrielle I Alfonso, Marisa Cobanaj, Amelia Morel Fiske, Alexander J Gates, Frances Dominique V Ho, Mohammad Kashkooli, Naira Link

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Interventional real-time molecular MRI for targeting early myocardial injury in a pig model by Timo Heidt, Simon Reiss, Julien Thielmann, Christian Weber, Alexander Maier, Thomas Lottner, Heidi R. Cristina-Schmitz, Timon Bühler, Diana Chiang, Claus Jülicher, Carolin Wadle, Ingo Hilgendorf, Dennis Wolf, Gavin Tumlinson, Luis Hortells, Dirk Westermann, Michael Bock, Constantin von zur Mühlen

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Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase by Jiaqian Wu, Marek R. Baranowski, Alexander E. Aleshin, Eta A. Isiorho, Lester J. Lambert, Laurent J. S. De Backer, Ye Na Han, Ranajit Das, Douglas J. Sheffler, Andrey A. Bobkov, Alexis M. Lemberikman, Daniel A. Keedy, Nicholas D. P. Cosford, Lutz Tautz

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Supervised Injecting Room Cohort Study (SIRX): study protocol by Lisa Maher, Thomas Kerr, Matthew Hickman, Alexander Thompson, Peter Higgs, Paul Dietze, Paul A Agius, Nick Scott, Daniel O’Keefe, Mark A Stoové, Jack Stone, Dylan Vella-Horne, Ashleigh C Stewart, Amanda Roxburgh, Sione Crawford, Josephine Norman, Zachary Lloyd, Nico Clark

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Constraints on Relativistic Jets from the Fast X-Ray Transient 210423 Using Prompt Radio Follow-up Observations by Dina Ibrahimzade, R. Margutti, J. S. Bright, P. Blanchard, K. Paterson, D. Lin, H. Sears, A. Polzin, I. Andreoni, G. Schroeder, K. D. Alexander, E. Berger, D. L. Coppejans, A. Hajela, J. Irwin, T. Laskar, B. D. Metzger, J. C. Rastinejad, L. Rhodes

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The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. by Alexander M Cole, Dorothy L Patton, Lisa C Rohan, Amy L Cole, Yvonne Cosgrove-Sweeney, Nicole A Rogers, Deena Ratner, Alexandra B Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I Lehrer, Alan J Waring, Phalguni Gupta

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Characterisation of the antibody-mediated selective pressure driving intra-host evolution of SARS-CoV-2 in prolonged infection. by Michael Schoefbaenker, Theresa Günther, Eva Ulla Lorentzen, Marie-Luise Romberg, Marc Tim Hennies, Rieke Neddermeyer, Marlin Maybrit Müller, Alexander Mellmann, Chiara Robin Bojarzyn, Georg Lenz, Matthias Stelljes, Eike Roman Hrincius, Richard Vollenberg, Stephan Ludwig, Phil-Robin Tepasse, Joachim Ewald Kühn

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Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS) by Delfina Larrea, Kirstin A. Tamucci, Khushbu Kabra, Kevin R. Velasco, Taekyung D. Yun, Marta Pera, Jorge Montesinos, Rishi R. Agrawal, Carmen Paradas, John W. Smerdon, Emily R. Lowry, Anna Stepanova, Belem Yoval-Sanchez, Alexander Galkin, Hynek Wichterle, Estela Area-Gomez

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A guide for developing comprehensive systems biology maps of disease mechanisms: planning, construction and maintenance by Alexander Mazein, Marcio Luis Acencio, Irina Balaur, Adrien Rougny, Danielle Welter, Anna Niarakis, Anna Niarakis, Diana Ramirez Ardila, Ugur Dogrusoz, Piotr Gawron, Venkata Satagopam, Venkata Satagopam, Wei Gu, Wei Gu, Andreas Kremer, Reinhard Schneider, Reinhard Schneider, Marek Ostaszewski, Marek Ostaszewski

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Minimally invasive determination of pancreatic ductal adenocarcinoma (PDAC) subtype by means of circulating cell‐free RNA by Martin Metzenmacher, Gregor Zaun, Marija Trajkovic‐Arsic, Phyllis Cheung, Timm M. Reissig, Hendrik Schürmann, Nils vonNeuhoff, Grainne O'Kane, Stephanie Ramotar, Anna Dodd, Steven Gallinger, Alexander Muckenhuber, Jennifer J. Knox, Volker Kunzmann, Peter A. Horn, Jörg D. Hoheisel, Jens T. Siveke, Smiths S. Lueong

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The Role of Nonmetastatic Lymph Nodes in the Survival of Colorectal Cancer: A Systematic Review by Alexander J. Pennings, MSc, Brecht A. van der Velden, BSc, Maximilian Kloft, MSc, Loes F. S. Kooreman, MSc, Jos M. P. Kleijnen, PhD, Stephanie O. Breukink, PhD, Geerard L. Beets, PhD, Heike I. Grabsch, PhD, Jarno Melenhorst, PhD

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Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated colorectal cancer—results from the FIRE‐4.5 study by Susanne Klein‐Scory, Alexander Baraniskin, Wolff Schmiegel, Thomas Mika, Roland Schroers, Swantje Held, Kathrin Heinrich, David Tougeron, Dominik P. Modest, Ingo Schwaner, Jan Eucker, Rudolf Pihusch, Martina Stauch, Florian Kaiser, Christoph Kahl, Meinolf Karthaus, Christian Müller, Christof Burkart, Sebastian Stintzing, Volker Heinemann

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The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells by Po-An Tai MD, PhD, Yen-Lin Liu MD, PhD, Ya-Ting Wen MD, Chien-Min Lin MD, PhD, Thanh-Tuan Huynh MD, PhD, Michael Hsiao DVM, PhD, Alexander T. H. Wu PhD, Li Wei MD, PhD

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Rabies seropositive individuals, dogs, and healthcare professionals without prior vaccination in four Brazilian Indigenous communities. by Matheus Lopes Ribeiro, Camila Michele Appolinario, Bruna Letícia Devidé Ribeiro, João Henrique Farinhas, Fernando Rodrigo Doline, Gisely Toledo Barone, Juliana Amorim Conselheiro, Vamilton Alvarés Santarém, Leandro Meneguelli Biondo, Andrea Pires Dos Santos, Rogério Giuffrida, Louise Bach Kmetiuk, Alexander Welker Biondo, Jane Megid

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Novel Intraoperative Near-Infrared Fluorescence Camera System for Optical Image-Guided Cancer Surgery by J. Sven D. Mieog, Alexander L. Vahrmeijer, Merlijn Hutteman, Joost R. van der Vorst, Maurits Drijfhout van Hooff, Jouke Dijkstra, Peter J.K. Kuppen, Rob Keijzer, Eric L. Kaijzel, Ivo Que, Cornelis J.H. van de Velde, Clemens W.G.M. Löwik

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Immunotherapeutic Potential of the Yellow Fever Virus Vaccine Strain 17D for Intratumoral Therapy in a Murine Model of Pancreatic Cancer by Alina S. Nazarenko, Yulia K. Biryukova, Kirill N. Trachuk, Ekaterina A. Orlova, Mikhail F. Vorovitch, Nikolay B. Pestov, Nick A. Barlev, Anna I. Levaniuk, Ilya V. Gordeychuk, Alexander S. Lunin, Grigory A. Demyashkin, Petr V. Shegai, Andrei D. Kaprin, Aydar A. Ishmukhametov, Nadezhda M. Kolyasnikova

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Dynamics of SARS-CoV-2 infection over two epidemic waves in Manaus, Brazil: A serological study of seven thousand blood donors. by Neal Alexander, Christopher Dye, Michael P Busch, Lewis Buss, Carlos A Prete, Oliver J Brady, Paul Mee, Claudia M M Abrahim, Myuki A E Crispim, Allyson G da Costa, Tassila Salomon, Philippe Mayaud, Márcio K Oikawa, Nuno R Faria, Ester C Sabino

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The VertiGO! Trial protocol: A prospective, single-center, patient-blinded study to evaluate efficacy and safety of prolonged daily stimulation with a multichannel vestibulocochlea... by Bernd L Vermorken, Benjamin Volpe, Stan C J van Boxel, Joost J A Stultiens, Marc van Hoof, Rik Marcellis, Elke Loos, Alexander van Soest, Chris McCrum, Kenneth Meijer, Nils Guinand, Angélica Pérez Fornos, Vincent van Rompaey, Elke Devocht, Raymond van de Berg

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