Clonal hematopoiesis in patients with autoimmune thrombocytopenia: an international multicenter study by Bruno Fattizzo, Alfredo Marchetti, Alessandro Bosi, Carmelo Gurnari, Juri Alessandro Giannotta, Giacinto Luca Pedone, Elena Rossi, Valentina Carrai, Andrea Guido, Filippo Brioschi, Monica Carpenedo, Monica Crugnola, Domenica Caramazza, Livia Leuzzi, Monia Marchetti, Gabriele Merati, Simona Malato, Fabrizio Vianello, Andrea Patriarca, Hussein Awada, Marta Bortolotti, Marta Canzi, Niccolò Bolli, Marco Capecchi, Frederick Chen, Andrea Artoni, Jaroslaw P. Maciejewski, Wilma Barcellini

“…Additionally, clonal hematopoiesis was associated with increased thrombotic risk (26% vs 8% in NGS-negative cases; P = .01), independently from TPO-RA exposure, though with an age effect. These data demonstrated the prevalence of clonal hematopoiesis in 18% of adult patients with ITP, which is associated with older age, relapsed/refractory disease, and high risk of thrombotic complications.…”
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Detecting respiratory impairment in newly diagnosed rheumatoid arthritis by MRC dyspnoea scale and microfibrillar-associated protein 4 by Bjørk K. Sofiudottir, Sören Möller, Robin Christensen, Stefan Harders, Grith L. Sørensen, Jesper Blegvad, Mette Herly, Dzenan Masic, Grazina Urbonaviciene, Frank Andersen, Christin Isaksen, Brian Bridal Løgstrup, Charlotte Hyldgaard, Torkell Ellingsen

“…The primary outcomes were the MRC and MFAP4’s sensitivity, specificity, and diagnostic odds ratio (DOR) with 95% confidence intervals (CI).Results One hundred and thirty-one patients had available baseline tests. Mean age was 57.7 years (SD: 10.9), 61% were female, and 45% had respiratory impairment. …”
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Factors affecting patient satisfaction during endoscopic procedures by Maryam Ghazala, E-Hinna Rashk, Sardar Saman, Khan Jahangir, Isram Javaria, Hassan Fayyaz

“…The study also found that certain aspects of the endoscopic procedure impacted satisfaction differently across gender and age groups. The questionnaire demonstrated strong internal consistency with a Cronbach's Alpha value of 0.917. …”
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Correlation between antenatal and postnatal coiling index and its role in prediction of perinatal outcome: A prospective cohort study by Ankita Kumari, Vani Aditya, Shaila Mitra, Garima Maurya, Pratima Sharma, Harish Chandra Tiwari

“…Materials and Methods: This prospective cohort study was conducted on 124 antenatal cases of age group 18–35 years with term gestation with singleton pregnancy that attendant the outpatients department and indoor of Department of Obstetrics and Gynecology, Nehru Hospital B.R.D. …”
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Analysis of tracheal, bronchial, and lung cancer attributable to respiratory system-related risk factors in 204 countries and territories from 1990 to 2019 by Shiwen Yu, Liangwei Yang, Weiwen Xu, Tian Zhao, Liyuan Han, Guofang Zhao, Ting Cai

“…Results From 1990 to 2019, the age-standardized DALY rate and death rate of TBL cancer only attributable to ambient particulate matter pollution increased globally, and in all Socio-Demographic Index (SDI) quintiles, except for high SDI quintiles. …”
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Genetic Markers Can Predict Chondrogenic Differentiation Potential in Bone Marrow-Derived Mesenchymal Stromal Cells by Masami Kanawa, Akira Igarashi, Katsumi Fujimoto, Yukihito Higashi, Hidemi Kurihara, Masaru Sugiyama, Tania Saskianti, Yukio Kato, Takeshi Kawamoto

“…The expression levels of the group 2 genes were significantly correlated with the ages of the cell donors. The expression levels of CDKN2D, CD74, and TGM2 were >10-fold higher in highly potent MSCs (ilium MSCs) than in MSCs with limited potential (jaw MSCs). …”
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Maternal Diet Supplementation with n-6/n-3 Essential Fatty Acids in a 1.2 : 1.0 Ratio Attenuates Metabolic Dysfunction in MSG-Induced Obese Mice by Josiane Morais Martin, Rosiane Aparecida Miranda, Luiz Felipe Barella, Kesia Palma-Rigo, Vander Silva Alves, Gabriel Sergio Fabricio, Audrei Pavanello, Claudinéia Conationi da Silva Franco, Tatiane Aparecida Ribeiro, Jesuí Vergílio Visentainer, Elton Guntendeorfer Banafé, Clayton Antunes Martin, Paulo Cezar de Freitas Mathias, Júlio Cezar de Oliveira

“…Newborn mice were treated with monosodium L-glutamate (MSG, 4 mg g−1 body weight per day) for the first 5 days of age. A batch of weaned pups was sacrificed to quantify the brain and pancreas total lipids; another batch were fed a commercial diet until 90 days of age, where glucose homeostasis and glucose-induced insulin secretion (GIIS) as well as retroperitoneal fat and Lee index were assessed. …”
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Validity and reliability of the Malay language Perception Towards Smoking Questionnaire (BM-PTSQ) among secondary school adolescents: Further validation using Confirmatory Factor A... by Kuang Hock Lim, Yoon Ling Cheong, Hui Li Lim, Kee Chee Cheong, Mohd Hazilas Mat Hashim, Ali Aman Marine, Yong Kang Cheah, Jia Hui Lim, Sumarni Mohd Ghazali

“…Methods We administered the BM-PTSQ to 669 secondary school students selected through multistage sampling; 60% of respondents were male (n=398), and 69.9% (n=463) were from rural areas. Respondents were aged 13–16 years, 36.4% (n=241) were 13 years, 40.0% (n=265) were 14 years, and 23.6% (n=156) were 16 years old. …”
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Effect of Reformation of the Anterior Chamber by Air or by a Balanced Salt Solution (BSS) on Corneal Endothelium after Phacoemulsification: A Comparative Study by Alahmady Hamad Alsmman, Mohammed Ezzeldawla, Amr Mounir, Ashraf Mostafa Elhawary, Osama Ali Mohammed, Mahmoud Farouk, Ahmed Mohamed Sherif

“…A prospective interventional nonrandomized comparative study included 500 eyes of 500 patients with age range between 50 and 60 years, prepared for cataract surgery and presented to the Ophthalmology department of Sohag University Hospital in the period from October 2016 to May 2017. …”
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Spinal presentations in children with type 1 spinal muscular atrophy on nusinersen treatment across the SMA-REACH UK network: a retrospective national observational study by Francesco Muntoni, Giovanni Baranello, Pinki Munot, Mariacristina Scoto, Adnan Manzur, Marion Main, Evelin Milev, Lianne Abbott, Victoria Selby, Amy Wolfe, Annemarie Rohwer, Catherine Rye, Sarah Gregson, Grainne NicFhirleinn, Rosanna Raab, Heather McMurchie, Angela Topping, Faye Mason, Jennie Sheehan, Felicity Vann, Steph Wadsworth, José Longatto, Lindsey Pallant, Nick Emery, Jenny Moustoukas, Sarah D’Urso, Kay White, Efthymia Panagiotopoulou

“…Background Prior to the introduction of disease-modifying treatments (DMTs), children with type 1 spinal muscular atrophy (SMA) typically did not survive beyond the age of 2 years; management was mainly palliative. …”
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Heart transplantation: comparing the impact of modified heart preservation with conventional methods by Xiaoke Shang, Changdong Zhang, Yixuan Wang, Mei Liu, Yucheng Zhong, Nianguo Dong

“…However, it was found that patient factors such as diagnostic classification, recipient age, and donor age significantly influenced mortality risk and were strongly associated with patient survival. …”
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Analysis of Changes in Retinal Thickness in Type 2 Diabetes without Diabetic Retinopathy by Jing Jiang, Yan Liu, Yingchao Chen, Bo Ma, Yiwen Qian, Zhenzhen Zhang, Dongqing Zhu, Zhiliang Wang, Xiaofang Xu

“…Confounding variables, such as age, gender, and glycated haemoglobin (HbA1c) level, were assessed by regression analysis. …”
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Ultrasound-guided Hydrostatic Reduction of Acute Intussusception in Children at a Tertiary Care Center: An Observational Study by Ajay Kumar Yadav, Neha Yadav, Binit Dev, Sonia Dahal, Rohit Prasad Yadav, Sushil Taparia, Hiramani Pathak

“…Results: Total 81 patients with 84 intussusceptions underwent ultrasound guided hydrostatic reduction with male to female ratio of 2.86 and mean age 9.49±8.43 months. Hydrostatic reduction was successful in 78 (92.85%) cases. …”
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Word Processing Is Faster than Picture Processing in Alzheimer’s Disease by Kenichi Meguro, Yumi Takahashi, Masahiro Nakatsuka, Jiro Oonuma, Keiichi Kumai, Mari Kasai, Satoshi Yamaguchi

“…Methods. 56 patients with probable AD (NINCDS-ADRDA, mean age 79.0 years) and 11 healthy controls (HC) (mean age 67.0 years) were studied. …”
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Effect and factors associated with reactivation after intravitreal conbercept or aflibercept in retinopathy of prematurity by Chunling Huang, Weikang Zou, Wenbei Ma, Jiali Li, Yichen Bai, Rong Wu, Qiqi Li, Qi Fang, Wenna Chen, Xiaohe Lu, Songfu Feng

“…Zone, stage, and gestational age were associated with the reactivation of ROP. …”
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Clinical Characteristics and Visual Outcomes of Patients Hospitalized for Ocular Trauma in Shandong Province, China by Fangnan Duan, Xiunian Chen, Sai Zhang, Xiaolin Qi, Weiyun Shi, Hua Gao

“…A total of 1,425 patients (1,622 eyes), aged 39.5 ± 18.5 years, were included. The ratio of male to female was 5.3 : 1. …”
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Comparative Evaluation of Tear Film and Corneal Surface in Chronic Smokers and Non Smokers: A Cross-sectional Study by Ruchi Dabas, Meena Kumari, Manisha Rathi, Monika Dahiya, Rajni Yadav, Sumit Sachdeva

“…All participants underwent a series of measurements: Schirmer I test, Tear Breakup Time (TBUT), Central Corneal Thickness (CCT) and endothelial cell count using specular microscopy. Results: The mean age of smokers was 50.15±6.89 years, whereas the mean age of non smokers was 49.25±6.39 years, with a significant male preponderance. …”
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A 10-Year Risk Assessment and Primary Prevention Study of Atherosclerotic Cardiovascular Disease Among Adult Patients in Saudi Arabia: A Cross-Sectional Study by Abdulhameed Alkhalaf, Qasem Aljabr, Khalid Al Mulla, Duaa Almubarak, Abdul Sattar Khan, Zainab Y. Al Jaziri, Ibrahim Albahrani

“…<i>Materials and Methods</i>: This cross-sectional study included 58,743 adults aged 35–75 years from the Al-Ahsa Health Cluster. …”
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Impact of Comprehensive Health Insurance affiliation on mortality in children under one year: an analysis of the Demographic and Health Survey 2010–2022 in Peru by Marcos Espinola-Sánchez, Marcos Espinola-Sánchez, Andres Campaña-Acuña, Diego Urrunaga-Pastor, Diego Urrunaga-Pastor, Jorge L. Maguiña, Manuel Jumpa, Oscar Ugarte-Ubillus

“…ObjectiveTo assess the impact of Comprehensive Health Insurance (CHI) coverage on mortality in children under 1 year of age in the Peruvian population from 2010 to 2022. …”
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Disparity of serum uric acid threshold for CKD among hypertensive and non-hypertensive individuals by Bowen Zhu, Fang Li, Weidong Zhang, Shuan Zhao, Nana Song, Shi Jin, Ziyan Shen, Yufei Lu, Yang Li, Hong Liu

“…In the propensity score matched (PSM) population, the result remained roughly constant.Conclusion Therefore, even moderate levels of sUA was associated with a higher risk of CKD in middle-aged hypertensive patients, who warrant stricter sUA control.…”
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