The additional impact of metabolic syndrome on left ventricular deformation and myocardial energetic efficiency impairment in ischemia with nonobstructive coronary arteries patient... by Chen-Yan Min, Yue Gao, Yuan Li, Yi-Ning Jiang, Ying-Kun Guo, Hua-Yan Xu, Rong Xu, Xi Liu, Li-Ting Shen, Zhi-Gang Yang

“…Materials and methods This study collected 104 INOCA patients (INOCA [MetS−]: n = 56; INOCA [MetS+]: n = 48) and 41 sex- and age-matched controls. LV function, indexed myocardial energetic efficiency (MEEI), and LV global peak strains (including radial, circumferential, and longitudinal directions) were measured among the three groups. …”
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Effects of exercise and exercise timing on energy intake and appetite control in Danish individuals with overweight or obesity with and without type 2 diabetes: a protocol for a ra... by Louise Groth Grunnet, Martin Bæk Blond, Jonas Salling Quist, Kristine Beaulieu, Graham Finlayson, Kristine Færch, Lea Jalking, Natja Poder Launbo, Marie Møller Jensen, Hanne Enghoff Pedersen, Marina Kjærgaard Gerstenberg

“…Fifty-eight women and men (aged 18–75 years) with overweight or obesity (body mass index ≥25 kg/m2) with or without T2D will be recruited. …”
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A randomised controlled implementation trial of the feasibility and effectiveness of school staff delivery of a selective substance use and mental health program during the COVID-1... by Lucinda Grummitt, Kirsty Rowlinson, Joanne Cassar, Chloe Conroy, Louise Birrell, Lexine Stapinski, Emma Louise Barrett, Julia Macauley, Maree Teesson, Nicola C. Newton, Erin V. Kelly

“…Of these, 40% had elevated scores on one of the four personality profiles, resulting in 220 students in the current study (102 students in intervention schools, 118 students in control schools; mean age 13.6, 45.7% female). Most RE-AIM domains showed high ratings, with school staff showing good adherence and confidence in delivery. …”
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Individualized Tailor-Made Dietetic Intervention Program at Schools Enhances Eating Behaviors and Dietary Habits in Obese Hispanic Children of Low Socioeconomic Status by Leticia Elizondo-Montemayor, Diana Moreno-Sànchez, Norma G. Gutierrez, Fabiola Monsivais-Rodriguez, Ubaldo Martinez, Ana C. Lamadrid-Zertuche, Martin M. Hernandez-Torre

“…Prospective school year dietetic intervention of 101 obese, Hispanic, low-socioeconomic school-age children representative of Monterrey, Mexico, consisted of anthropometrics, dietetic assessment, energy-restriction tailor-made daily menus, and parental education every three weeks. …”
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Atrial fibrillation outcomes in patients from Asia and non-Asia countries: insights from GARFIELD-AF by Karen Pieper, Xian-hong Fang, Kai Sun, Ajay K Kakkar, Saverio Virdone, Shinya Goto, Gloria Kayani, Zhi-Cheng Jing, John Camm, Chun-Yan Cheng, Tian-Yu Lian, Xi-Jie Zhu, Xian-Mei Li

“…The association of geographical region with clinical outcomes (event rates per 100 person-years) were estimated using multivariable Cox models.Results 13 841/52 057 (26.6%) GARFIELD-AF participants were enrolled in Asia. Average age and prevalence of cardiovascular comorbidities were lower than in non-Asian countries and patients at high risk of stroke (ie, CHA2DS2-VASc≥2 excl. sex) were less frequently anticoagulated (60.1% vs 73.2%). …”
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Prediction of outpatient rehabilitation patient preferences and optimization of graded diagnosis and treatment based on XGBoost machine learning algorithm by Xuehui Fan, Ruixue Ye, Yan Gao, Kaiwen Xue, Zeyu Zhang, Jing Xu, Jingpu Zhao, Jun Feng, Yulong Wang

“…Driven by chronic diseases and an aging population, there is a need to enhance the efficiency and resource allocation of outpatient facilities. …”
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Pancreaticoduodenectomy in trauma patients with grade IV–V duodenal or pancreatic injuries: a post hoc analysis of an EAST multicenter trial by Jeffry Nahmias, Daniel N Holena, Bellal Joseph, Martin Schreiber, Lisa M Kodadek, Mayur Narayan, Grace Chang, Joe Patton, Abid Khan, Mark Seamon, Jessica H Beard, Michelle T Bover Manderski, Michael A Vella, Ryan Peter Dumas, Haytham Kaafarani, Alison A Smith, Rachel Leah Choron, Christopher Bargoud, Amanda L Teichman, Francesk Mulita, Christine T Trankiem, Hashim Ahmed, Aaron Anderson, Odessa Pulido, Caleb Mentzer, Jane Keating, Mira Ghneim, Reynold Henry, Dane R Scantling, Andrew Benjamin, Christopher W Foote, Carlos H Palacio, Randi N Smith, Meghan Jonikas, Dias Argandykov, Jason D Sciarretta, Joshua P Hazelton, Pascal Udekwu, Jordan Michael Kirsch, Charoo Piplani, Julia Kuzinar, Dustin Hanos, Iman N Afif, Navpreet Kaur Dhillon, Ashling Zhang, Rebekah Devasahayam, Oliver Gunter, Brandi Sun, Chloe S Cao, Jessica K Reynolds, Lauren A Hilt, Karla Echeverria-Rosario, Nathaniel S Fung, Caitlin A Fitzgerald, Jeremy H Levin, JaeHee Yoon, Jacqueline Blank, Christopher J McLaughlin, Rami Al-Aref, Daniel S Howard, Kate Dellonte, Brent Hopkins, Chloe Shell, Evan G Wong, Howard Lieberman, Walter A Ramsey, Collin H Stewart, Claudia Alvarez, John D Berne, Ivan Puente, Ilya Rakitin, Lindsey Perea, Jason Wade, Laura K Mann, Vasileios Mousafeiris, Shari Reid-Gruner, Erica Sais, Lilamarie Moko

“…Included patients were ≥15 years of age with the American Association for the Surgery of Trauma grade IV–V duodenal and/or pancreatic injuries. …”
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Effects of the Oral Health Promotion Program on oral health and oral microbiota changes in diabetic elderly individuals: a quasi-experimental study by Fan Liu, Siping Song, Shuqi Huang, Jing He, Xin Ye, Liwei Hu, Xin Zeng, Sicheng Deng, Xiuying Hu

“…Oral health was measured via the oral health impact profile (OHIP-14) questionnaire, dental plaque index, HbA1c and mastery of oral health knowledge, and sequencing of the 16S rRNA gene from saliva samples was used to analyze the oral microbiota. Results The average age of the final sample was 71.77 years (SD = 6.06), 53.8% (28/52) of whom were male. …”
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Use of 3D-DXA in the assessment of bone structure among patients with chronic kidney disease by Martin Kužma, Zuzana Kužmová, Ludovic Humbert, Mirella Lopez Picazo, Roman Králik, Jakub Falat, Juraj Smaha, Peter Jackuliak, Zdenko Killinger, Juraj Payer

“…Bone mineral density (BMD) assessment is limited due to the inability to measure trabecular and cortical bone characteristics and the interference of aortic calcifications.Study objectiveThis study aimed to assess the trabecular bone score (TBS) and three-dimensional dual-energy X-ray absorptiometry (3D-DXA) in participants across all CKD stages.Patients and methodsIn total, 64 CKD patients (consisting of 28 female participants and 36 male participants, with an average age of 69.5 years) were included. There were 9, 12, 8, 9, 11, and 15 participants in stages G1, G2, G3a, G3b, G4, and G5 of CKD, respectively. …”
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A sex-disaggregated analysis of the prognostic value of lean type 2 diabetes mellitus in the adult population with acute myocardial infarction by Gwyneth Kong, Jaycie Koh, Jobelle Chia, Bryan Neo, Yiming Chen, Grace Cao, Bryan Chong, Mark Muthiah, Hui Wen Sim, Gavin Ng, Chieh Yang Koo, Chin Meng Khoo, Mark Yan-Yee Chan, Poay-Huan Loh, Nicholas W. S. Chew

“…Cox regression model was constructed to investigate the associations of lean and non-lean T2DM phenotypes with mortality, adjusted for age, ethnicity, previous AMI, AMI type, chronic kidney disease, angiotensin converting enzyme inhibitor or angiotensin receptor blockers, beta-blockers, and smoking status. …”
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Efficacy and safety of everolimus for patients with focal cortical dysplasia type 2 by Se Hee Kim, Hoon‐Chul Kang, Yun Ho Roh, Jongsung Hahn, Kyung Lok Min, Seok‐Jin Lee, Donghwa Yang, Han Som Choi, Soyoung Park, Jeong Ho Lee, Sang‐Guk Lee, Se Hoon Kim, Min Jung Chang, Heung Dong Kim

“…Methods A prospective, crossover, placebo‐controlled clinical trial (ClinicalTrials.gov: NCT03198949) enrolled patients aged 4–40 years with pathologically confirmed FCD 2 and a history of ≥3 seizures per month for two out of the 3 months prior to screening. …”
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Factors influencing role preferences in decision-making of healthy women with BRCA1/2 pathogenic variants: subanalysis from a randomised controlled decision coaching trial by Sibylle Kautz-Freimuth, Arim Shukri, Claudia Stracke, Anna Isselhard, Birte Berger-Höger, Anke Steckelberg, Frank Vitinius, Nicola Dikow, Marion Kiechle, Cornelia Meisel, Achim Wöckel, Marion Tina von Mackelenbergh, Rita Schmutzler, Kerstin Rhiem, Stephanie Stock

“…Furthermore, in the IG, younger age (OR 1.049, 95% CI 1.001–1.098, p = 0.044) and a non-academic education (OR 0.46, 95% CI 0.213–0.775, p = 0.006) were identified as significant predictors for taking a more active role. …”
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Decreased sirtuin 1 in type 2 diabetes patients with abnormal BMD by Yao Xu, Tianxiao Hu, Peiwu Jiang, Xiujing Wang, Jiaqi Yao, Huiling Shen, Zhenying Zhang, Bojing Zheng, Ting Wang, Yanxia Ren, Jing Wang, Qingying Tan

“…Logistic regression indicated that Sirtuin 1, age, HDL-C, P1NP, and β-CTX were independent risk factors for osteoporosis in T2DM patients.DiscussionIn conclusion, decreased serum Sirtuin 1 levels are associated with bone turnover markers in T2DM patients and may serve as an independent risk factor and potential biomarker for diagnosing bone metabolism disorders in newly diagnosed T2DM patients.…”
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Conhecimento dos pacientes com câncer avançado sobre seu diagnóstico e modalidade de tratamento by Leonel dos Santos Silva, Ana Paula Felicio de Lima, Cleo Watanabe Pisaia, Lourdes Maria Rosinski Lima Gomes, Natália Naome Oshiro, Paulo Ricardo Bittencourt Guimarães, Luciana de Alcantara Nogueira, Luciana Puchalski Kalinke

“…Results: A total of 101 participants were included, with a mean age of 56.8 years; 73.3% were women (p<0.05), 38.6% had breast cancer (p<0.05), and multiple metastases; 49.5% were aware of the advanced cancer diagnosis (p<0.05), 30.7% were unaware of the disease stage, 37.6% did not understand the treatment objectives, and 33.7% believed the treatment was curative; 94.1% had not been advised on non-pharmacological therapy by a healthcare professional (p<0.05). …”
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Therapeutic potential of rutin in premenstrual depression: evidence from in vivo and in vitro studies by Xiangjun Wang, Xiaowen Xia, Xianliang Song, Yi Zhou, Mingyu Ma, Yashuang Ren, Xitai Chen, Zenghui Xia, Yinghui Guo, Chunhong Song

“…IntroductionPremenstrual dysphoric disorder (PMDD) is a cyclical mood disorder that severely affects the daily life of women of reproductive age. Most of the medications being used clinically have limitations such as low efficacy, side effects, and high cost, so there is an urgent need to discover safer and more effective medications. …”
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Deltopectoral approach without subscapularis detachment for reverse shoulder arthroplasty. Technique and results of a safe and reproducible subscapularis-sparing approach by Adrien Jacquot, MD, MSc, Thomas Cuinet, MD, Lisa Peduzzi, MD, Patrice Wong, MD, Marc-Olivier Gauci, MD, PhD, Julien Uhring, MD

“…The subscapularis was intact in all the cases. The mean age at inclusion was 74.1 years. No patients were lost at the minimum 24-month follow-up. …”
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Beyond identification of familial hypercholesterolemia: Improving downstream visits and treatments in a large health care system by Harin Lee, Tarun Kadaru, Ruth Schneider, Taylor Triana, Carol Tujardon, Colby Ayers, Mujeeb Basit, Zahid Ahmad, Amit Khera

“…Results: A total of 242 patients from the FH registry were reviewed of which 108 (mean age 55, 69 % women, highest mean LDL-C 267 ± 47 mg/dL) met the inclusion criteria. …”
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Modulatory effect of Echium plantagineum oil on the n-3 LC-PUFA biosynthetic capacity of chicken (Gallus gallus) by Jesús Villora, José Antonio Pérez, Nieves Guadalupe Acosta, Deiene Rodríguez-Barreto, Pedro Juan Alonso, Mónica B. Betancor, Alexandr Torres, Sergio Álvarez, Covadonga Rodríguez

“…To explore this hypothesis, 60 Canarian male chickens at 18 weeks of age were divided into three groups and fed diets differing only in their FA formulation: soy oil (SO) rich in linoleic acid (LA, 18:2n-6); linseed oil (LO) rich in ALA; and EO, a balanced LA/ALA oil also rich in SDA and γ-linolenic acid (GLA, 18:3n-6). …”
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Meibomian gland alterations in allergic conjunctivitis: insights from a novel quantitative analysis algorithm by Jingting Wei, Jingting Wei, Kunhong Xiao, Qingyuan Cai, Qingyuan Cai, Shenghua Lin, Xiangjie Lin, Yujie Wang, Yujie Wang, Jiawen Lin, Kunfeng Lai, Yunxi Ye, Yuhan Liu, Li Li

“…Correlation analysis revealed that the gland dropout ratio was positively associated with male gender and negatively associated with age and OSDI scores. Additionally, despite an increased number of MG, tear film stability was not improved.ConclusionThrough the intelligent quantitative algorithm, we found that AC leads to significant changes in MG structure, particularly affecting gland length and central area.…”
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Preoperative and Postoperative Bone Mineral Density Change and Risk Factor Analysis in Patients with a GH-Secreting Pituitary Adenoma by Li’nan Qin, Xiaopeng Guo, Lu Gao, Zihao Wang, Chenzhe Feng, Kan Deng, Wei Lian, Bing Xing

“…Results. The average patient age and disease duration were 43.74 (33.41–54.07) years and 72.15 (22.82–121.48) months, respectively. …”
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