Longitudinal DNA methylation profiles in saliva of offspring from mothers with gestational diabetes: associations with early childhood growth patterns by Teresa M. Linares-Pineda, Alfonso Lendínez-Jurado, Alberto Piserra-López, María Suárez-Arana, María Pozo, María Molina-Vega, María José Picón-César, Sonsoles Morcillo

“…Samples were collected at two time points: 8–10 weeks postpartum and at one year of age. Epigenome-wide analysis of over 850,000 CpG sites was conducted using the Illumina Methylation EPIC Bead Chip. …”
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Investigating the effect of using a home safety training application by caregivers on accident risk management in the elderly by Mahdie Dehnavi, Najmeh Valizadeh zare, Seyd Reza Mazlom, Samira Mohajer, Tahereh Sadeghi, Mohammad Namazinia, Danial Baghie

“…Results: Sixty-two elderly caregivers participated in the study, with a mean age of 72 ± 37.7 years. The chi-square test showed no significant difference in gender distribution between the intervention and control groups (p = 0.060). …”
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Changes of Lacrimal Puncta by Anterior Segment Optical Coherence Tomography after Topical Combined Antibiotic and Steroid Treatment in Cases of Inflammatory Punctual Stenosis by Islam Awny, Elshimaa A. Mateen Mossa, Tasneem Mohammed Bakheet, Hany Mahmoud, Amr Mounir

“…Both groups were comparable regarding mean age (49 ± 13 vs 53 ± 11 years, P value = 0.2) and sex (males were 38.6% vs 31.8%, female were 61.4% vs 68.2%, P value = 0.6), respectively, with no statistically significant difference between both groups. …”
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Effect of KRAS mutation status on clinicopathological characteristics and overall survival in patients with rectal cancer by Shengbin Zheng, Zhijie You, Guodon Guo, Zhijing Lin, Siming Wang, Guohua Yang

“…Results The mKRAS group included 100 patients(51.8%) and had no significantly difference in age, sex, distance from anus, tumor node metastasis(TNM), lymphovascular invasion(LVI), grade differentiation, and perineural invasion(PNI), carcinoembryonic antigen(CEA) level than that in wKRAS group.KRASG12D group had significantly more poorer differentiation(9/34,26.5% vs. 10/93,10.7%,p = 0.046), PNI(24/34,70.6%vs.42/93,45.2%,p = 0.016) and higher TD(8/34,23.5% vs.8/93,8.6%,p = 0.035) respectively, p < 0.05. …”
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Assessing Physician and Patient Agreement on Whether Patient Outcomes Captured in Clinical Progress Notes Reflect Treatment Success: Cross-Sectional Study by Sarah B Floyd, Jordyn C Sutton, Marvin Okon, Mary McCarthy, Liza Fisher, Benjamin Judkins, Zachary Cole Reynolds, Ann Blair Kennedy

“…Cohen κ statistics were used to assess the degree of agreement between physicians and patients on clinical note content. ResultsThe average age of the patients in the sample was 67 (SD 13) years and 82% of the notes came from female patients. …”
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Determinants of Anemia among HIV-Positive Children on Highly Active Antiretroviral Therapy Attending Hospitals of North Wollo Zone, Amhara Region, Ethiopia, 2019: A Case-Control St... by Biruk Beletew, Ayelign Mengesha, Mohammed Ahmed, Awet Fitwi, Mesfin Wudu

“…On multivariate analysis, variables which have spastically significant association with anemia were as follows: had amebiasis (AOR = 7.29, 1.22–43.56), had history of opportunistic infections (AOR = 9.63, 1.94–47.85), had malaria infection (malaria pf) (AOR = 4.37, 1.16–16.42), eating nondiversified food (AOR = 10.39, 2.25–48.0), WGT-Age Z score value between −2_−3 (AOR = 9.80, 2.46–39.14), level of adherence (AOR = 2.31, 1.92, 7.77), and being from a rural area (AOR = 8.8, 2.07–37.79). …”
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The AFFIRM Framework for gender-affirming care: qualitative findings from the Transgender and Gender Diverse Health Equity Study by Meg Quint, Schuyler Bailar, Alexis Miranda, Shalender Bhasin, Devin O’Brien-Coon, Sari L. Reisner

“…Results Participants had a mean age of 28.5, ranging 18–45 years, and were: 7 transgender men, 6 transgender women, 8 nonbinary, 3 genderqueer, 1 agender, and 2 gender not specified. …”
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Recombinant α-Klotho Protein Alleviated Acute Cardiorenal Injury in a Mouse Model of Lipopolysaccharide-Induced Septic Cardiorenal Syndrome Type 5 by Xi Liu, Yangyang Niu, Xiaoqin Zhang, Yingying Zhang, Ying Yu, Jieli Huang, Jiangtao Li, Chen Yu

“…Background and Aims. Klotho is an aging-suppressor gene mainly expressed in the renal tubules. …”
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Effect of motivational interviewing to promote advance care planning among palliative care patients in ambulatory care setting: a randomized controlled trial by Helen Yue-Lai Chan, Doris Yin-Ping Leung, Po-Tin Lam, Polly Po-Shan Ko, Raymond Wai-Man Lam, Kin-Shan Chan

“…Results A total of 204 participants (mean [SD] age, 74.9 [10.8]; 64.7% male; 80.4% cancer) were recruited. …”
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Do coping strategies mediate the effects of childhood adversities and traumata on clinical high-risk of psychosis, depression, and social phobia? A cross-sectional study on patient... by Zhixiong Chang, Naweed Osman, Carolin Martha Doll, Theresa Katharina Lichtenstein, Marlene Rosen, Eva Meisenzahl, Hanna Kadel, Joseph Kambeitz, Kai Vogeley, Frauke Schultze-Lutter

“…Methods Using path analyses, we analyzed data of 736 patients (mean age 24 years, 67% male) who presented at an early detection service between 2002 and 2013, answered questionnaires on CAT, coping, depressiveness, and social phobia, and underwent clinical examination for CHR-P according to the recommendations of the Guidance project of the European Psychiatric Association. …”
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Therapeutic alliance impact on analgesic outcomes in a real-world clinical setting: An observational study by Barrachina Jordi, Margarit César, Andreu Blanca, Zandonai Thomas, Ballester Pura, Muriel Javier, Cutillas Esperanza, Peiró Ana M.

“…Patients were predominantly middle-aged (75 % women, 72 % retired), experiencing moderate pain (VAS 40–70 mm) on average, and under a high morphine equianalgesic dosage (95 ± 88 mg per day, mainly tapentadol or fentanyl). …”
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Extended Reality Interventions for Health and Procedural Anxiety: Panoramic Meta-Analysis Based on Overviews of Reviews by Tom Arthur, GJ Melendez-Torres, David Harris, Sophie Robinson, Mark Wilson, Sam Vine

“…Here, outcomes were estimated for patients (level 1), studies (level 2), and anxiety indications (level 3), while meta-regressions explored possible influences of age, immersion, and different mechanisms of action. …”
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A case-matched series comparing functional outcomes for robotic-assisted unicompartmental knee arthroplasty versus functionally aligned robotic-assisted total knee arthroplasty by Jonathan R. Manara, Macdaniel Nixon, Beth Tippett, Wil Pretty, Dermot Collopy, Gavin W. Clark

“…Patients were matched for preoperative BMI, sex, age, and Forgotten Joint Score (FJS). A total of 101 matched pairs were eligible for final review. …”
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Effect of Remote Home Rehabilitation Mode on Children with Cerebral Palsy and Their Families during Epidemic Isolation by Tingting XU, Yunfei QIAO, Mao HUANG

“…The exercise training content mainly refered to"exercise guidance and advice for children aged 0-6 years old during the epidemic of COVID-19", once a day, 30 minutes each time, five times a week, continuous intervention for one month. …”
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Heterogeneity of motivations among crowdinvestors: Evidence from the football industry by Szczepan Kościółek

“…The segments were also differentiated according to consumption-related behaviors (media consumption, word-of-mouth marketing, merchandise purchases, match attendance, and social media engagement) and socio-demographic profiles (age, marital status, income, and place of residence). …”
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Association between air pollutants and blood cell counts in pediatric patients with asthma: a retrospective observational study by Kuo-Chen Huang, Hsiu-Yung Pan, Ting-Min Hsieh, Chih-Cheng Chen, Fu-Jen Cheng

“…Methods This retrospective observational study, performed in 2007–2018 at a medical center, enrolled non-trauma patients aged < 17 years who visited the emergency department and had asthma. …”
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Whole-transcriptome analysis reveals the profiles and roles of coding and non-coding RNAs during hair follicle cycling in Rex rabbits by Jie Wu, Jiamin Zhai, Haofan Jia, Ifeanyi Solomon Ahamba, Xianggui Dong, Zhanjun Ren

“…Results In this study, we identified the hair follicle stages of Rex rabbits aged 3 to 5.5 months. Skin samples collected at 4, 5 and 5.5 months, representing the morphological features of the anagen, catagen and telogen stage separately, were finally selected for whole-transcriptome analysis. 25,736 mRNA, 8280 lncRNA, 24,885 circRNA and 1138 miRNA transcripts were identified. 6027 differently expressed mRNAs (DEGs), 2381 differently expressed lncRNAs (DELs), 438 differently expressed circRNAs (DECs) and 167 differently expressed miRNAs (DEMs) were detected in the anagen vs. catagen (AvC) comparison. 4092 DEGs, 1540 DELs, 356 DECs and 141 DEMs were detected in the anagen vs. telogen (AvT) comparison. 2290 DEGs, 779 DELs, 249 DECs and 92 DEMs were detected in the catagen vs. telogen (CvT) comparison. …”
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The evolving landscape of COVID-19: factors associated with in-hospital COVID-19 related mortality during the 2023–2024 phase of JN.1 subvariant dominance by Drieda Zaçe, Albiana Çekrezi, Christopher Jones, Ludovica Ferrari, Giuseppe De Simone, Elisabetta Teti, Vincenzo Malagnino, Marco Iannetta, Loredana Sarmati, Anna Maria Geretti

“…Results Among 122 individuals (median age 76 years, 58.2% males, median comorbidity index 5), 114/122 (93.4%) had received ≥ 1 SARS-CoV-2 vaccination, with a median of 23 months elapsed since the last dose. …”
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Patients admitted in an Intensive Care Unit with severe clinical manifestations of Influenza, october-december 2009 by Yenisey Quintero Mendez, Jorge Luis Ulloa Capestani, Rudis Monzón Rodríguez, Francisco García Valdés, Ramón E Álvarez Cepero, Jaime Geroy Gómez, Pablo Rodríguez Díaz, Alfredo Dario Espinosa Brito, Yanli Vázquez Villazón, Diley Moreno Ruiz, Octavio Rivero Rodríguez

“…There were 62 women (56,9%), of which 19 were pregnant or postpartum women (17,4%). The mean age of the sick persons of this serie was of 52,53 ± 22,54 years. …”
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Protocol for a prospective quasi-experimental study on SARS-CoV-2 transmission during outdoor sports events in France: the COVID-ESO project by Frédéric Laurent, Philippe Vanhems, Christelle Elias, Pascal Roy, Sandrine Nail-Billaud, Patrick Basset, Emmanuelle Dantony, Mathieu Fauvernier

“…Individuals will be matched (1:1) on age, sex and the district of residence. Individuals assigned to the exposed group will participate in the OSE, whereas individuals assigned to the unexposed group will not participate in the OSE. …”
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