CHROMOGRANIN-A IN THE DIAGNOSIS OF PROSTATE CANCER by A. V. Sivkov, N. G. Keshishev, G. D. Efremov, G. A. Kovchenko, A. A. Trudov, L. M. Nikonova, F. D. Romikh

“…According to the analysis they revealed no significant correlation between age and HGA (r = 0,05) among all study groups. They noted the persistent correlation (r = 0,32; p <0,001) between HGA and PSA levels among all studied groups of patients. …”
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Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction by Irene López-Ferreruela, Sara Malo, Blanca Obón-Azuara, María José Rabanaque, Adriana Gamba, Sara Castel-Feced, Isabel Aguilar-Palacio

“…The proportion of subjects initiating treatment was similar in both genders. Overall, age and morbidity burden were the main contributors to differences in the prescribing patterns. …”
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Single-arm multicenter phase II study on aggressive local consolidative therapy in combination with systemic chemotherapy for stage IV non-small cell lung carcinoma with oligometas... by Takaaki Tokito, Kazuhiko Yamada, Hidenobu Ishii, Yuichi Takiguchi, Go Saito, Koichi Minato, Hisao Imai, Hiroshi Tanaka, Satoru Miura, Kageaki Watanabe, Yoshifusa Koreeda, Akira Ono, Naoki Furuya, Toshihiro Misumi, Kazushige Hayakawa, Etsuyo Ogo, Hiroaki Okamoto

“…Results We enrolled 19 patients between June 2016 and May 2020. The median age was 68 (range: 51–74) years. Twelve patients had adenocarcinoma, and 6 had squamous cell carcinoma. …”
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Physical symptoms distress and demoralization among haemodialysis patients; the mediating effect of spirituality and self-compassion. A cross-sectional questionnaire survey by Chia-Hui Lin, Yi-Chien Chiang, Wen-Yi Li, Tsung-Lan Chu, Ya-Chu Hsiao

“…Results: A total of 156 participants participated. Mean age of participants was 61.3 years (SD = 11.3). …”
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Release velocity ImprovemenT with a new Metronome guIding chest COmpressions: The RITMICO simulation study by Maria Luce Caputo, Giuliana Monachino, Ruggero Cresta, Alessia Currao, Enrico Baldi, Simone Savastano, Andrea Cortegiani, Mariachiara Ippolito, Sara Accetta, Alessandra Gargano, Camilla Metelmann, Bibiana Metelmann, Carlos Ramon Hölzing, Julian Ganter, Michael Patrick Müller, Claudio Benvenuti, Stefania Tomola, Pierangelo Pinetti, Pier Luigi Ingrassia, Francesca Dalia Faraci, Angelo Auricchio

“…Results: 503 volunteers participated in the study, with 54% being male and a mean age of 34 ± 12 years. The median CCRV and CC depth achieved with the double-click metronome were significantly higher compared to the standard metronome (median difference 6 mm/s, IQR-15.2, 28.5, +1.5%, p < 0.001; median difference 0.1 cm, +2.5%, IQR −0.1, 0.4, p < 0.001). …”
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Subclinical patterns of cardiac involvement by transthoracic echocardiography in individuals with mild initial COVID-19 by Anastasia Shchendrygina, Mame Madjiguène Ka, Carlos Rodriguez, Safaa Alsoufi, Jedrzej Hoffmann, Parveen Kumar, Maria Ludovica Carerj, Byambasuren Vanchin, Niels Holm, Argyro Karyou, Mijidsuren Ganbat, Eike Nagel, Valentina O. Puntmann

“…A total of 343 infected individuals (163 males; age 44 (interquartile range, IQR 35–52) years) years) underwent serial TTE assessments at a median of 109 (interquartile range (IQR), 77–177) and 327 (276–379) days after infection. …”
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Monitoring changes of forest height in California by Samuel Favrichon, Jake Lee, Yan Yang, Yan Yang, Ricardo Dalagnol, Ricardo Dalagnol, Fabien Wagner, Le Bienfaiteur Sagang, Le Bienfaiteur Sagang, Sassan Saatchi, Sassan Saatchi, Sassan Saatchi

“…This study demonstrates the benefits of using locally trained ML models to rapidly modernize forest management techniques in the age of increasing climate risks.…”
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Cross-sectional association among dietary habits, periodontitis, and uncontrolled diabetes in Hispanics: the LLIPDS study by Hunter Smith, David Travis Thomas, Gabriela Nicole Vázquez-Morales, Lakin Puckett, María Del Mar Rodriguez, Arnold Stromberg, Luciana Macchion Shaddox, Mauro Pedrine Santamaria, Kevin Pearce, Oelisoa Mireille Andriankaja

“…This study aimed to explore whether food choices were linked to higher prevalence of adverse periodontal parameters and poorly controlled glucose levels among Hispanic adults with T2D.MethodsA cross-sectional study was conducted with 260 Puerto Rican adults aged 40–65 years, all diagnosed with T2D. Dietary habits were assessed by weekly frequencies of food choices deemed healthy or unhealthy over the past year. …”
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Characteristics and Outcomes of 79 Patients with an Insulinoma: A Nationwide Retrospective Study in Finland by Elina Peltola, Päivi Hannula, Heini Huhtala, Saara Metso, Ulla Kiviniemi, Martine Vornanen, Juhani Sand, Johanna Laukkarinen, Mirja Tiikkainen, Camilla Schalin-Jäntti, Johanna Arola, Jukka Sirén, Antti Piiroinen, Minna Soinio, Pirjo Nuutila, Mirva Söderström, Hanna Hämäläinen, Leena Moilanen, David Laaksonen, Elina Pirinen, Fia Sundelin, Tapani Ebeling, Pasi Salmela, Markus J. Mäkinen, Pia Jaatinen

“…The median diagnostic delay was 13 months and did not change over the study period. The mean age at diagnosis was 52 (SD 16) years. The overall imaging sensitivity improved from 39% in the 1980s to 98% in the 2000s (p<0.001). …”
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Intersectional discrimination, exclusion and the socio-political economy of global mental health: A systematic scoping review of the literature by Rochelle A. Burgess, Sorcha Ní Chobhthaigh, Bijayalaxmi Biswal, Diana Ceccolini, Babatunde Fadipe, Denaneer Khan, Neena Aggarwal, Ishrat Pabla, Camila Solis, Ramya Pillutla, Piyali Sarkar, Eric Frasco, Valentina lemmi, Soumitra Pathare, Crick Lund

“…In this scoping review, we explore the extent to which the current mental health evidence base acknowledges the impact of intersectional structural determinants of mental health outcomes, via the mechanism of discrimination - linked to a range of commonly underexplored socio-political factors (Protocol registration DOI:10.17605/OSF.IO/CGJQH).We included nine social phenomena widely acknowledged in social theory as contributing to the patterning of social determinants: (1) Political Dynamics, (2) Racism, Caste &amp; Xenophobia, (3) Gender &amp; Sexuality, (4) Neighbourhood Dynamics, (5) Class &amp; Working conditions, (6) Colonialism, (7) Indigeneity, (8) Religious &amp; Spiritual Identities (9) Age &amp; Disability. We explored these factors intersectionally, including studies with two or more factors in their analyses. …”
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Geographic disparities in physical and mental health comorbidities and socioeconomic status of residence among Medicaid beneficiaries in Utah by Roberta Z. Horth, Roberta Z. Horth, Roberta Z. Horth, Srimoyee Bose, Srimoyee Bose, Carl Grafe, Carl Grafe, Navina Forsythe, Angela Dunn

“…Our analysis included Medicaid beneficiaries with geocoded addresses aged ≥18 years in Utah (N = 157,739). We geocoded beneficiary addresses and assigned them to census block groups. …”
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Quality assessment of spent laying hens and analysis of influencing factors by Runzhe Wang, Jiahui Lai, Guiyun Xu, Chuanwei Zheng, Zhiqiong Mao, Jiangxia Zheng

“…We selected spent laying hens at 100 weeks of age as the research subjects to explore the factors influencing their market price. …”
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The Effectiveness of Modified Atkins Ketogenic Diet on Children with Intractable Epilepsy: A Pilot Study from Indonesia by Achmad Rafli, Setyo Handryastuti, Mulya Rahma Karyanti, Yoga Devaera, Cut Nurul Hafifah, Irawan Mangunatmadja, Muzal Kadim, Elisabeth Siti Herini, Lora Sri Nofi, Ariek Ratnawati, Suci Fitrianti

“…This is a pilot experimental study involving children aged 2–18 years old with intractable epilepsy at the Pediatric Neurology and the Pediatric Nutrition & Metabolic Diseases Clinics at the Dr. …”
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Clinical impact of proteinuria on renal function and treatment outcomes in patients with radioiodine-refractory thyroid cancer treated with lenvatinib by Naoki Fukuda, Kazuhisa Toda, Hirotaka Suto, Ryosuke Oki, Xiaofei Wang, Tetsuya Urasaki, Yasuyoshi Sato, Kenji Nakano, Makiko Ono, Junichi Tomomatsu, Hiroki Mitani, Shunji Takahashi

“…Multivariate analysis revealed that age [&gt;65; odds ratio (OR) 8.24, 95% confidence interval (CI) 1.74–39.00, p &lt; 0.01], history of diabetes mellitus (OR 7.79, 95% CI 1.31–46.20, p = 0.02), and hypertension (OR 4.07, 95% CI 1.22–13.60, p = 0.02) were significantly associated with the development of grade 3 proteinuria. …”
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Reliability of the OMERACT Giant cell arteritis Ultrasonography Score (OGUS): results of a patient-based exercise involving experts and non-experts in vascular ultrasonography by Christian Dejaco, Stavros Chrysidis, Sara Monti, Cristina Ponte, Peter Mandl, Lene Terslev, Bhaskar Dasgupta, Alojzija Hočevar, Christina Duftner, Wolfgang Schmidt, Carlos Pineda, Eugenio De Miguel, Andreas P Diamantopoulos, Helen Keen, Kati Mykkänen, George A Bruyn, Wolfgang Hartung, Maria Antonietta D’Agostino, Nikitas Gkikopoulos, Luca Seitz, Adela-Cristina Sarbu, Eva Manger, Berit Dalsgaard Nielsen, Norbert Redlinger, Veerendra Chadachan, Maria Correyero, Giovanni Fulvio, Vesselina Kurteva, Paolo Mercatelli, Irina Midtgard, Raili Muller, Duriad Reffat

“…Inter-reader and intra-reader reliability were assessed by intraclass correlation coefficient (ICC).Results Mean age of GCA patients was 78±5.1 years, 2 (33.3%) were women, and all were in clinical remission. …”
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Nomograms Predicting Survival, Recurrence and Beneficiary Identification of Adjuvant Chemotherapy in Treatment-naïve Patients with Rectal Cancer who Underwent Upfront Curative Rese... by Yukihide Kanemitsu, MD, Tomofumi Uotani, MD, Shunsuke Tsukamoto, PhD, Hideki Ueno, PhD, Megumi Ishiguro, PhD, Soichiro Ishihara, PhD, Koji Komori, PhD, Kenichi Sugihara, PhD, Study Group for Nomogram of the Japanese Society for Cancer of the Colon and Rectum

“…In the training cohort, age predicted survival, venous invasion predicted recurrence, and sex, tumor location, histological type, preoperative carcinoembryonic antigen, invasion depth, lymphatic invasion, positive radial margin, and numbers of metastatic nodes and examined nodes predicted both. …”
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Vestibular Infant Screening-Rehabilitation (VIS-REHAB): protocol for a randomised controlled trial on Vestibular Rehabilitation Therapy (VRT) in vestibular-impaired children by Ruth Van Hecke, Leen Maes, Ingeborg Dhooge, Marieke Fontaine, Cleo Dhondt, Frederic Acke, Lena Van den Bossche, Helen Van Hoecke, Els De Leenheer

“…The study includes patients aged 3–17 years old with identified peripheral vestibular dysfunction. …”
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Serum adropin levels as a potential biomarker for predicting diabetic kidney disease progression by I-Wen Chen, I-Wen Chen, Cheng-Wei Lin, Cheng-Wei Lin, Cheng-Wei Lin, Chia-Ni Lin, Chia-Ni Lin, Szu-Tah Chen, Szu-Tah Chen, Szu-Tah Chen

“…The association with CKD progression was still significant after adjusting for age, gender and body mass index (adjusted odds ratio = 27.188, 95% confidence interval 1.415-522.527, P =0.029).ConclusionsThe above findings suggest that serum adropin could be applied as a potential biomarker for predicting CKD progression in subjects with T2D. …”
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Rare renal proximal tubular dysfunctions in primary biliary cholangitis by Xiaoxiao Shi, Tianchen Guo, Yubing Wen, Wei Ye, Wenling Ye, Ke Zheng, Yan Qin, Xuemei Li, Fengchun Zhang, Limeng Chen

“…Their medical document, kidney pathology, and follow-up data were retrospectively reviewed and analyzed.Results The 11 PBC-PT patients were mainly middle-aged (57.8 ± 5.2 years) females (81.8%). Most of them were asymptomatic PBC (7, 63.6%) with a high prevalence of elevated serum immunoglobulin M (IgM, 81.8%) and G (IgG, 54.5%) levels. …”
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The association between folic acid supplementation, maternal folate during pregnancy and intelligence development in infants: a prospective cohort study by Shaokang Wang, Jie Wei, Di Wang, Li Hua, Da Pan, Lingmeng Fu, Jin Yang, Guiju Sun

“…Pregnant women (n = 478) and their corresponding infants were followed up and the Developmental Screen Test scores were recorded at 1,3,6,8 and 12 months of age. Results: Compared with the normal group, infants in the low serum folate group had a score of 0.12 points lower in the intellectual energy zone (95% CI: -0.23 – -0.01, P = 0.04), and infants with the high homocysteine level scored 1.30 points lower than the lower-level group (95% CI: -2.52 – -0.08, P = 0.04). …”
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