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29761
Challenges with achieving and maintaining oral cholera vaccine coverage: insights from serial cross-sectional representative surveys in a cholera-endemic community in the Democrati...
Published 2025-01-01“…We used an exponential decay model to predict the proportion of the population vaccinated with ≥1 dose of kOCV over time based on age-specific coverage.Results We enrolled 8735 participants from 1433 households across all surveys. …”
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29762
Association of thoracic aortic calcium with incident cardiovascular disease and all-cause mortality across the spectrum of coronary artery calcium burden
Published 2025-03-01“…Cox proportional hazards regression assessed the association of TAC with incident CVD and all-cause mortality over a median follow-up of 17.7 years, adjusting for CVD risk factors and CAC. Results: The mean age was 62.1 years old, 53% were female, and 28% had TAC. …”
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29763
Identification of genetic mechanisms of non-isolated auditory neuropathy with various phenotypes in Chinese families
Published 2025-01-01“…Results A total of 11 variants linked to non-isolated AN were identified in this study, eight of which were novel. Patients’ age of hearing loss onset ranged from 2 to 25 years, averaging 11 years. …”
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29764
Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian population
Published 2024-09-01“…The study findings revealed that most of NAFLD patients were males (71.4%), aged around 39.6±10.86 years, with BMI indicating overweight (27.68 ± 4.25 Kg/m2). …”
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29765
Hypofractionated partial breast irradiation after breast-conserving surgery for patients with early stage breast cancer in China Mainland: a single-arm prospective trial
Published 2025-01-01“…Abstract To report the results of a single-arm, prospective partial breast irradiation (PBI) trial from China mainland using a dose of 40.05 Gy in 15 fractions delivered with intensity-modulated radiation therapy (IMRT) technique for patients with early stage breast cancer. Patients aged ≥ 50 years who underwent breast-conserving surgery for unifocal non-lobular invasive breast cancer, with pathological T1 disease, clear margins, negative axillary nodes, and positive hormonal receptors, were recruited. …”
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29766
Trends to shorter diagnostic delay in spondyloarthritis patients during the last decades and association with clinical presentation: data from ASAS-COMOSPA study
Published 2025-01-01“…Diagnostic delay showed a progressive decrease during the last decades, patients with disease onset after 2010 showed a shorter delay in diagnosis than those with disease onset during 2000–2010 (m 2.00 vs 0.41 years, p<0.01). Age at disease onset (OR 1.02), axial symptom (OR 16.25), peripheral arthritis (OR 6.81), decade at disease onset (OR 3.80) and extra-musculoskeletal manifestation (OR 2.89) were associated with an early diagnosis, while female gender (OR 0.66) was inversely associated.Conclusions The proportion of patients with early SpA diagnosis improve from 15% before 1980 to 88% when first symptoms occurred after 2010. …”
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29767
Association of Cardiovascular Autonomic Neuropathy and Distal Symmetric Polyneuropathy with All-Cause Mortality: A Retrospective Cohort Study
Published 2021-01-01“…Of the participants, 53%/43% were male, mean age was 46±12/64±10 years, diabetes duration was 13±10/7±8 years, 42%/29% had CAN, and 39%/37% had DSPN. …”
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29768
Assessing the Comparative Efficacy and Safety of Warfarin and Rivaroxaban for Cancer Associated Thrombosis: Experience From a Resource Limited Setting
Published 2025-01-01“…The baseline mean (standard deviation) age of the patients was 48.4 (15.0) and 140 (69.7%) of them were female. 41.3% of the participants had one or more comorbidities, and the most common types of cancer were gynecologic (28.9%), hematologic (21.4%), and intra‐abdominal (16.9%). …”
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29769
Efficacy and safety of ondansetron orally soluble pellicle for preventing moderate- to high-emetic risk chemotherapy-induced nausea and vomiting
Published 2025-01-01“…The major efficacy rate for nausea (no nausea) was 96.3%. Age > 65 years was negatively associated with major efficacy for vomiting, and a chemotherapy regimen involving cisplatin was negatively associated with major efficacy for nausea. …”
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29770
Study protocol on risk factors for the diagnosis of gestational diabetes mellitus in different trimesters and their relation to maternal and neonatal outcomes (GDM-RIDMAN)
Published 2022-07-01“…Oral glucose tolerance test results will be used to identify glucose dysregulation, and maternal and neonatal outcomes include maternal weight gain, pre-eclampsia, polyhydramnios, mode of delivery, preterm or postdate birth, complications in labour, birth weight, gestational age at birth, Apgar score, congenital anomaly, congenital hypothyroidism, neonatal death or stillbirth, hypoglycaemia and hyperbilirubinaemia. …”
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29771
Chemotherapy plus therapeutic plasmapheresis with 4% human albumin solution in multiple myeloma patients with acute kidney injury: a prospective, open-label, proof-of-concept study
Published 2024-12-01“…Bortezomib-based chemotherapy plus therapeutic plasmapheresis (TPP) with 4% human ALB solution was assessed for three years in patients with MM aged >18 years, with AKI according to the Kidney Disease Improving Global Outcomes criteria, and without previous renal impairment from other causes. …”
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29772
Exploring the impact of genetic factors and fatty acid quality on visceral and overall Fat levels in overweight and obese women: a genetic risk score study
Published 2025-01-01“…Methods In this study, 278 overweight and obese women (aged 18–58) participated. We have used a comprehensive food frequency questionnaire (FFQ) to evaluate dietary intake and the fatty acids quality indexes. …”
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29773
Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study)
Published 2022-07-01“…Hence, in this study, we aim to determine the prevalence, severity, risk factors and impact on quality of life of persisting symptoms in the first year following acute SARS-CoV-2 infection.Methods and analysis The LongCOVID-study is both a prospective and retrospective cohort study being conducted in the Netherlands, with a one year follow-up. Participants aged 5 years and above, with self-reported positive or negative tests for SARS-CoV-2 will be included in the study. …”
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29774
improving Pain mAnagement for childreN and young people attendeD by Ambulance (PANDA): protocol for a realist review. [version 3; peer review: 2 approved, 1 approved with reservati...
Published 2025-01-01“…Background Each year in England, 450,000 children and young people (CYP) under 18 years of age are transported by ambulance to emergency departments. …”
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29775
The clinical impact of recent amphetamine exposure in aneurysmal subarachnoid hemorrhage patients
Published 2025-01-01“…No significant differences were found in respect to patient age, sex, or admission clinical severity scales (Hunt-Hess and modified Fisher) based on amphetamine use. …”
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29776
Downsystem grain-size trends and mass balance of an ancient wave-influenced sediment routing system: Middle Jurassic Brent Delta, northern North Sea, offshore UK and Norway
Published 2025-01-01“… We reconstruct spatial variations in grain size in the sediment routing system of the data-rich Middle Jurassic Brent Group of the northern North Sea, using published stratigraphic, thickness, palaeogeographic, provenance and age constraints combined with representative core and wireline-log data. …”
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29777
Psychometric properties of the Arabic emotional and behavioral reaction to intrusions questionnaire among sample of Arabic speaking adults
Published 2025-02-01“…Results A total of 755 participants completed the survey, with a mean age of 21.89 ± 4.18 years and 77.5% females. CFA indicated a modest fit for the one-factor model. …”
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29778
Symptoms of anxiety and depression among health and social science students: A multicenter study
Published 2025-01-01“…Country-specific factors associated with more depressive and/or anxiety symptoms were younger age, smoking, low socioeconomic level and living away from home. …”
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29779
Pharmacist-led DE-eSCALation of opioids post-surgical dischargE (DESCALE) – A multi-centre, non-randomised, feasibility study protocol [version 2; peer review: 1 approved, 2 approv...
Published 2025-01-01“…Methods DESCALE is a multicentre, non-randomised, pragmatic feasibility study. Participants aged ≥18 years who have undergone a surgical procedure at a single NHS trust in Southeast England and discharged with opioids and without a history of long-term opioid use, cancer diagnosis or study contraindications will be offered a Medicines Use Review (MUR) within 7-10 days of discharge. …”
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29780
Global, regional, and national burden of very early-onset colorectal cancer and its risk factors from 1990 to 2019: A systematic analysis for the global burden of disease study 201...
Published 2025-02-01“…Aims: Very early-onset colorectal cancer (EOCRC) was defined as CRC diagnosed before the age of 35 proposed by the latest EOCRC management guideline. …”
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