Nationwide observational study of incidence, management and outcome of spontaneous coronary artery dissection: a report from the Swedish Coronary Angiography and Angioplasty regist... by Per Tornvall, Eva Swahn, Dimitrios Venetsanos, Troels Yndigegn, Sofia Sederholm Lawesson, Lena Jonasson, Nina Johnston, Henrik Wilander, Christos Pagonis, Christian Dworeck, Thomas Kellerth

“…Patients with non-SCAD myocardial infarction (MI) (n=32 601) were used for comparison.Outcome measures Outcomes included all-cause mortality, reinfarction or acute coronary reangiography.Results This study found 147 SCAD patients, rendering an incidence of 0.74 per 100 000 per year and a prevalence of 0.43% of all MIs. The average age was 52.9 years, 75.5% were women and 47.6% presented with ST-segment elevation MI. …”
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Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT by Zhengwei Zhang, Shuimiao Chang, Kaiwen Li, Jinhan Yao, Zhao Wang, Jiewei Liu, Lin Jiang, Feiyan Chai, Xiaogang Wang

“…Results: Forty-six eyes of 27 patients (average age, 26.0 ± 5.3 years) were included in the final data analysis. …”
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Dietary Micronutrient Intake and the Prevalence of Metabolic Conditions among Children from the United States–Affiliated Pacific Region in the Children’s Healthy Living Program by Lucia A Seale, Ashley B Yamanaka, Kristi Hammond, Eunjung Lim, Lynne R Wilkens, Pauline McFall, Tanisha F Aflague, Patricia Coleman, Travis Fleming, Leslie Shallcross, Jonathan Deenik, Rachel Novotny

“…Objectives: The study examined the association between micronutrient intake with body mass index (BMI in kg/m2) and the presence of insulin resistance proxy, acanthosis nigricans (AN), in 3529 children aged 2–8 y from the USAP region in the Children’s Healthy Living study. …”
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A Rare Pediatric Giant Cell Tumor of the Clivus Bone, H3.3 p.Gly35Trp-mutated: Case Report and Mini-review of the Literature by Gabriele Gaggero, Teresa Battaglia, Virginia Andreotti, Andrea Rossi, Marta Ingaliso, Davide Taietti, Claudia Milanaccio, Gianluca Piatelli, Valerio Gaetano Vellone

“…Introduction: Giant cell tumor of bone (GCTB) is a rare, typically benign neoplasm that primarily affects long bones in adults, with clival involvement being extremely rare, particularly in pediatric cases: a mini-review shows a total of 28 described cases, of which only 5 were truly pediatric (within 14 years of age). Surgery is the treatment of choice, and Denosumab is reported to be the most effective drug therapy. …”
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Efficacy and Tolerance of Vascular Electrical Stimulation Therapy in the Management of Vaso-Occlusive Crises in Patients with Sickle Cell Disease: A Phase II Single-Centre Randomiz... by Renée-Paule Botti, Sie Saïda Bokoum, Etienne L’Hermite, Dohoma Alexis Silue, Boidy Kouakou, Sarah Anastasie Bognini, Serge Arnaud Agoua, Edgar Mandeng Ma Linwa, Roméo Ayemou, Kouassi Gustave Koffi

“…The secondary end points were median time to end-of-crisis, median tramadol consumption, progress of the haemoglobin level over 3 days, side effects, and treatment failure. Results. The age ranged from 14 to 37 years, including 23 women. …”
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Quantitative Validation of Hematocrit Percentage Drop Cutoff Points in Postpartum Hemorrhage: An Automated Gravimetric Approach by Venance Basil Kway, José Enrique Calacuayo Rojas, Josué Sidonio Rodríguez Cuevas, Ursula Medina Moreno, José Sergio Camacho Juárez, Jorge Francisco Ayala González, Karla Krebs Larraga, Ilse Veronica Castro Martinez, Roberto Arturo Castillo Reyther, Antonio Gordillo Moscoso, Yang Pan

“…A prospective cohort study was conducted from January 2023 to July 2023, in which 107 patients 18 years of age and above were scheduled for elective cesarean with obstetrical indications. …”
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Repetition of Prediabetes Enhances the Risk of Developing Diabetes by Yoshihiro Numata, Toshihide Ohya, Yasuhiko Nitta, Yumiko Yoshinaka, Azusa Shogakiuchi, Akihiro Toyota

“…Then, we surveyed the development of diabetes for 5 years, and the incidence rates (IRs) and the age- and sex-adjusted odds ratios (ORs) were obtained. …”
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Colorectal cancer in Lynch syndrome families: consequences of gene germline mutations and the gut microbiota by Xuexin Wang, Zhijun Zheng, Dongliang Yu, Xiaojue Qiu, Ting Yang, Ruoran Li, Jing Liu, Xin Wang, Peng Jin, Jianqiu Sheng, Nan Qin, Na Li, Junfeng Xu

“…Results There were no apparent differences in age or gender among the four groups. Alpha and beta diversity indices exhibited no significant differences between the AS and BS groups, verifying the role of germline mutations in the occurrence of CRC in LS families. …”
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Superior biomechanical stability of pedicle screws compared to lateral mass screws: recommendations for bicortical positioning and enhancing bone contact in geriatric C1 vertebrae by Leon-Gordian Leonhardt, Leonie Rörup, Anna Lena Kammal, Michael Hahn, Marc Dreimann, Benjamin Ondruschka, Felix Nikolai von Brackel, Tim Rolvien, Lennart Viezens, Simon von Kroge

“…Methods Human C1 from geriatric body donors (n = 28; 50% female, age 80.8 ± 13.9 years) were collected and characterized based on their bone microstructure. …”
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Acute Infusion-Related Side Effects of Amphotericin B Lipid Complex (ABLC) in Oncohematological Patients: Real-World Data from Brazilian Reference Centers by Francelise Bridi Cavassin, Marcello Mihailenko Chaves Magri, Ariela Victoria Borgmann, Isabela Dombeck Floriani, Marina Rachid Barreto, Tania Zaleski, Fabianne Altruda de Moraes Costa Carlesse, Giovanni Luís Breda, Fábio de Araújo Motta, Diego Rodrigues Falci, Ana Verena Almeida Mendes, Hugo Paz Morales, Patrícia Silva Montes, Mariane Taborda, Talita Teles Teixeira Pereira, João Luiz Baú-Carneiro, Flávio Queiroz-Telles

“…Results A total of 229 patients were included, with a male prevalence and an average age of 44 years for adults and 10 years for children. …”
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Impact of insurance payer type (medicare vs. private) on the patient reported outcomes after shoulder arthroplasty by Paul V. Romeo, MD, Aidan G. Papalia, MBA, Andrew J. Cecora, BS, Bradley A. Lezak, MD, Matthew G. Alben, DO, Dashaun A. Ragland, BS, Young W. Kwon, MD, PhD, Mandeep S. Virk, MD

“…Patients in the Medicare cohort were older (mean age 70.5 vs. 61.3 years), with high proportion of smokers, diabetics, and reverse total shoulder arthroplasty compared to the private payor cohort. …”
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Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK by Tim Doran, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Siobhan Reilly, Claire Planner, Ivan Olier, Linda Gask

“…We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.Design Retrospective cohort study from 2000 to 2012.Setting 627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.Participants Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.Outcome measures Prevalence rates were calculated for 16 conditions.Results SMI rates were highest in Scotland and in more deprived areas. …”
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Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease, by regulating LPCAT3 by Majd B. Protty, Victoria J. Tyrrell, Ali A. Hajeyah, Bethan Morgan, Daniela Costa, Yong Li, Anirban Choudhury, Rito Mitra, David Bosanquet, Alex Reed, Iuliia K. Denisenko, Katsuyuki Nagata, Hideo Shindou, Benjamin F. Cravatt, Alastair W. Poole, Takao Shimizu, Zaheer Yousef, Peter W. Collins, Valerie B. O’Donnell

“…Furthermore, the Lands cycle acyl-transferases that catalyze their formation are unidentified. eoxPL were measured in platelets and leukocytes from an atherosclerotic cardiovascular disease (ASCVD) cohort and retrieved human arterial thrombi from three anatomical sites. The impact of age, gender, and aspirin was characterized in platelets from healthy subjects administered low-dose aspirin. …”
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Direct-acting oral anticoagulant removal by intraoperative hemoadsorption in CABG and/or single valve surgery: interim analysis of the International Safe and Timely Antithrombotic... by Michael Schmoeckel, Matthias Thielmann, Keti Vitanova, Thomas Eberle, Nandor Marczin, Kambiz Hassan, Andreas Liebold, Sandra Lindstedt, Georg Mächler, Marijana Matejic-Spasic, Daniel Wendt, Efthymios N. Deliargyris, Robert F. Storey

“…Results A total of 62 patients were included from 7 institutions in Austria, Germany, Sweden, and the UK (mean age 69.9 ± 7.5years, 71% male). Approximately half were on apixaban and the other half was split between rivaroxaban and edoxaban with 21% of patients also on aspirin. …”
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Increased intake of marine fish contributed to a decreased odds of comorbid depressive symptoms and coronary heart disease in Chinese adults by Yuncao Fan, Wei Chen, Wenhui Lin, Jungu Jin, Enyu Lou, Jiaying Lao, Yu-Hsin Chen, Jianzhi Shao, Qizeng Wang, Qingxi Jiang, Fan Wang, Fan Wang, Jinzhong Xu, Yanlong Liu, Bo Yang

“…We aimed to investigate the relationship between consumption of marine fish and DCHD in Chinese adults.MethodsA cross-sectional study was conducted in 1,106 participants aged 25–95 years living in Taizhou, China. Fish intakes were assessed by using a validated food frequency questionnaire, with their tertiles as category levels of ≤1 time/week, 2–6 times/week, and ≥7 times/week. …”
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Access to healthcare: waiting time until the surgical procedure by Cassiane de Santana Lemos, Ana Maria Muller Magalhães, Danielle Saraiva Tuma dos Reis, Alessandra Yuri Takehana de Andrade, Karla Cristina de Almeida, Fabiana Zerbieri Martins, Nancy Reynolds, Vanessa de Brito Poveda

“…Data collection included socio-demographic data and assessment of quality of life using the WHOQOL-Bref instrument in the immediate postoperative period and one month after surgery.Results A total of 250 patients participated in the study, 55.6% patients from the Southeast, 20.4% patients from the North and 24% patients from the South, with a mean age of 51.86 (SD = 14.27) years and clinical history such as arterial hypertension (p < 0.001). …”
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Mammography Among Women Residing in Urban Versus Rural Utah: Breast Cancer Survival by Quinn Tanner, Chun‐Pin Chang, Karen Curtin, James VanDerslice, Lisa Gren, Vikrant Deshmukh, Michael Newman, Ankita Date, Mark Dodson, N. Lynn Henry, Mia Hashibe

“…Methods Cases (n = 14,516) were women aged > 39 diagnosed with a first primary invasive breast cancer between 1998 and 2017 in Utah. …”
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Characterization of heart failure patients with reverse left ventricular remodelling post‐angiotensin receptor blockers/neprilysin inhibitors therapy by Leonid Maizels, Yishay Wasserstrum, Boris Fishman, Amitai Segev, David Ben‐Nun, Anan Younis, Dov Freimark, Israel Mazin, Avishay Grupper

“…The cohort included 91 patients (mean age 60.5 years, 90% male) and 47 (52%) patients exhibited ARNI responsiveness, defined as an increase in LVEF during therapy. …”
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Transition Guide Dissemination to Foster Patient–Care Team Conversations: A Childhood Arthritis Rheumatology Research Alliance Transition Learning Collaborative Pilot Implementatio... by Joyce C. Chang, Gabrielle Alonzi, Cora Sears, Nicole Bitencourt, Alex Hernandez, Rosemary Peterson, Risa Alperin, Rebecca S. Overbury, Mariel dela Paz, Lindsay N. Waqar‐Cowles, Patience H. White, Kristine Carandang, Erica F. Lawson, for the CARRA Transition Workgroup

“…After implementation, there were significant increases in the likelihood of respondents recalling receiving a transition guide (odds ratio [OR] 2.58, 95% CI 1.35–4.92) and discussing transfer planning (OR 2.14, 95% CI 1.30–3.52), adjusted for age and site of care. Conclusion Transition guide dissemination is a simple intervention associated with increased awareness among young people with rheumatic conditions and discussions with their care team about transition preparation. …”
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Serum metalloproteinase-7 as a biomarker of progressive pulmonary fibrosis by Márcia Araújo, Marília Beltrão, Oksana Sokhatska, Natália Melo, Patrícia Caetano Mota, Helder Novais Bastos, André Terras, David Coelho, Luís Delgado, António Morais

“…MMP-7 was independently associated with PPF (adjusted OR 1.263, 95% CI 1.029–1.551; p=0.026) after adjustment for sex, age and smoking history. A cut-off value of 3.53 ng·mL−1 for serum MMP-7 levels had a sensitivity of 61% and a specificity of 74% for predicting PPF in non-IPF ILDs. …”
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