THE RESULTS OF MODULAR ENDOPROSTHESIS OF PERIACETABULAR REGION IN TUMOR LESIONS OF THE ACETABULUM AND HIP JOINT by G. D. Iluridze, V. Yu. Karpenko, V. A. Derzhavin, A. V. Bukharov

“…There were 13 men (43%) and 17 women (57%). The median age was 45 years (23–63 years). Primary bone cancers were in 19 (63%) patients, giant cell tumors in 5 (17%), locally advanced soft tissue sarcoma in 1 (3%), solitary metastases of kidney cancer in 2 (7%), and recurrent sarcomas after previous surgical treatment in 3 (10%) patients.Results. …”
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The safety of cyclosporine and tacrolimus in pediatric nephrotic syndrome patients: a disproportionate analysis based on the FAERS database by Yu Liu, Chong Yan, Yaowang Zhao, Sui Deng, Jiancheng Zu

“…ObjectiveThis study aimed to systematically evaluate the safety of cyclosporine (CsA) and tacrolimus (TAC) in pediatric nephrotic syndrome (NS) patients using real-world data from the FDA Adverse Event Reporting System (FAERS).MethodsWe analyzed adverse event (AE) reports from the FAERS database between Q4 2003 and Q2 2024, focusing on AEs associated with CsA and TAC in NS patients aged 18 years and younger. We employed three signal detection methods—Proportional Reporting Ratio (PRR), Relative Reporting Ratio (RRR), and Reporting Odds Ratio (ROR)—to assess the risk of drug-related AEs. …”
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PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood by Bo Han, Qiaobo Xie, Weishi Liang, Peng Yin, Xianjun Qu, Yong Hai

“…RNA extraction reverse transcription and quantitative polymerase chain reaction were conducted in the peripheral blood collected from six AS patients and six health volunteers matched by age and sex. Results. 125 DEGs were identified, consisting of 36 upregulated and 89 downregulated genes that are involved in the cell cycle and replication processes. …”
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The effect of continuous positive airway pressure (CPAP) application on airway problems in pediatric patients with subglottic stenosis who undergo balloon dilatation by Zeliha Tuncel, Şenay Göksu, Özlem Deligöz, Kemal Tolga Saracoglu, Abdulatif Albasha, Bushra M. Abdallah, Ayten Saracoglu

“…Methods A prospective, double-blinded, parallel-group, randomized controlled study was conducted at Health Sciences University Ümraniye Training and Research Hospital on pediatric patients with subglottic stenosis, aged from 0 to 12 years and who underwent elective balloon dilatation under general anesthesia. …”
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Implementation of a program to strengthen oral hygiene in patient with cleft deformities: a prospective randomized controlled clinical trial by Camille Boeffard, Justine Loin, Roselyne Clouet, Alexis Gaudin, Pierre Corre, Tony Prud’Homme

“…We aim to assess, through a single-center, prospective, randomized and controlled clinical trial conducted at the Nantes Cleft Centre, the impact of an enhanced dental program on oral hygiene and dental health in cleft patients. Methods Patients aged 3 to 15 years with unilateral or bilateral cleft lip and/or palate will be offered to participate in this study. …”
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Prognostic value of adjuvant chemotherapy for hormone receptor-negative T1a and T1bN0M0 breast cancer patients by Yaxiong Liu, Honghui Li, Jinsong Li, Changlong Wei, Jinsheng Zeng, Qiuhong Tian

“…Based on multivariate Cox regression analysis of OS, older age, single, T1b stage, triple-negative tumor and absence of adjuvant CT were identified as risk factors related to OS. …”
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Association of continuous renal replacement therapy downtime with fluid balance gap and clinical outcomes: a retrospective cohort analysis utilizing EHR and machine data by Chloe Braun, Tomonori Takeuchi, Josh Lambert, Lucas Liu, Sarah Roberts, Stuart Carter, William Beaubien-Souligny, Ashita Tolwani, Javier A. Neyra

“…Results We included 3630 CRRT patient-days from 500 patients with a median age of 59.5 years (IQR 50–67). Patients had a median SOFA score at CRRT initiation of 13 (IQR 10–16). …”
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Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models by Kathleen Bennett, Frank Moriarty, Tom Fahey, Caitriona Cahir

“…Objectives To determine the economic impact of three drugs commonly involved in potentially inappropriate prescribing (PIP) in adults aged ≥65 years, including their adverse effects (AEs): long-term use of non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines and proton pump inhibitors (PPIs) at maximal dose; to assess cost-effectiveness of potential interventions to reduce PIP of each drug.Design Cost-utility analysis. …”
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COVID-19 vaccine uptake in Zimbabwe and Sierra Leone: an application of Health Belief Model constructs by Simon Ssentongo, Alex Muhereza, Morie Mustapha, Ruth Gemi, Dennis Cherian, Rebecca Waugh, Benjamin Crookston, Cougar Hall, Mary Linehan, Hayden Borg, Joshua West

“…We then employed adjusted logistic regression models to investigate the correlation between health behavior change theory constructs and vaccine uptake, taking into account variables like gender, age, education, and country of residence. Results Several associations were identified, including high vaccine uptake correlated with a heightened perceived threat of COVID-19 (OR = 2.674; p < .001), recognized benefits of vaccination (OR = 1.482; p < .001), stronger perceived behavior control (OR = 2.189; p < .001), and fewer perceived barriers to vaccination (OR = 0.173; p < .001). …”
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Community credit scores and community socioeconomic deprivation in association with type 2 diabetes across an urban to rural spectrum in Pennsylvania: a case–control study by Jonathan Pollak, Melissa N Poulsen, Karen Bandeen-Roche, Katherine Moon, Joseph DeWalle, Annemarie G Hirsch, Brian S Schwartz, Lorraine Dean, Meghann Reeder

“…We analysed community credit scores (CCS) in association with new onset type 2 diabetes (T2D) across a geographically heterogeneous region of Pennsylvania and evaluated whether associations were independent of community socioeconomic deprivation (CSD), which is known to be related to T2D risk.Methods In a nested case–control study, we used medical records to identify 15 888 T2D cases from diabetes diagnoses, medication orders and laboratory test results and 79 435 diabetes-free controls frequency matched on age, sex and encounter year. CCS was derived from Equifax VantageScore V.1.0 data and categorised as ‘good’, ‘high fair’, ‘low fair’ and ‘poor’. …”
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Provider Adherence to the 2020 US Multi-Society Task Force Guidelines for Surveillance After Colonoscopy With Polypectomy by Benjamin E. Cassell, Katherine Scholand, Wyatt Tarter, Camille J. Hochheimer, Colleen Long, Gregory L. Austin

“…Among procedures with 1 to 2 TAs, age (OR 0.86 per 5-year increase; 95% CI: 0.75–0.99), increasing size (OR 0.86 per mm; 95% CI: 0.75–0.99) and polyp number (OR 0.54; 95% CI: 0.33–0.90) were associated with nonadherence. …”
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Dynamic assessment of long-term survival in survivors with stage III non-small cell lung cancer: a novel conditional survival model with a web-based calculator by Xiangdi Meng, Xiangdi Meng, Peihe Wang, Jie Liu, Daqing Sun, Zhuojun Ju, Yuanyuan Cai

“…Six independent predictors (age, tumor size, N status, surgery, radiotherapy and chemotherapy) were identified for the development of the CS-nomogram and its web version (https://dynapp.shinyapps.io/NSCLC/). …”
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Role of B7H4 and Fas in regulation of trophoblast cells and development of pre-eclampsia: a cross-sectional study by Xiujuan Dong, Cuicui Nie, Yanli Yin, Haixia Xu, Yanxia Zhang, Lihua Han, Congcong Xu

“…In addition, the clinical characteristics of all participants were collected, including age, gestational weeks at delivery, gestational time, number of births, systolic blood pressure, diastolic blood pressure and foetal weight. …”
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A Prospective Study Investigating the Health Outcomes of Bitches Neutered Prepubertally or Post-Pubertally by Rachel Moxon, Sarah L. Freeman, Richard M. Payne, Sandra Corr, Gary C. W. England

“…Additionally, PrePN bitches were diagnosed with atopic dermatitis (PrePN: 3.9 ± 0.6 years, PostPN: 1.6 ± 0.3 years; Mann–Whitney U test = 90.5, <i>p</i> = 0.008) and perivulval dermatitis (PrePN: 4.7 ± 0.9 years, PostPN: 0.8 ± 0.1 years; Mann–Whitney U test = 40.0, <i>p</i> = 0.002) at significantly older ages and had lower probabilities of remaining free from otitis externa (χ² = 7.090, D.F. = 1, <i>p</i> = 0.008). …”
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Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis by Maria J. Gutierrez, Stephen V. Desiderio, Nae-Yuh Wang, Erika Darrah, Laura Cappelli, Gustavo Nino, Michelle Jones, Clifton O. Bingham

“…Using the Johns Hopkins Arthritis Cohort and Biorepository, we contrasted serum protein levels of soluble factors involved in B-cell activation (CD40, CD40L) and B-cell/ASC homing (CXCL10, CXCL11, and CXCL13) or survival (BAFF, APRIL, TACI, and BCMA) in 10 healthy subjects and 23 adult RA patients (aged 24-65 years). We subdivided RA patients into those with (n=17) and those without infections (n=6) within a 2-year period. …”
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Should We Adopt Increased Dilutions for Indirect Immunofluorescence in Pediatric Anti-Centromere Antibody Testing? Insights from a Three-Year Retrospective Study by Mehmet Soylu, Raziye Burcu Taşkın, Gülçin Aytaç, Güzide Aksu, Seyfi Durmaz, Miray Karakoyun, Şaziye Rüçhan Sertöz

“…Correspondence analysis revealed significant associations between IIF dilution levels and immunoblot reactivity (χ² = 37.574, <i>p</i> < 0.000). Gender and age were not significant predictors of SARD positivity. …”
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Clinical Correlations of Novel Autoantibodies in Patients with Dry Eye by Sezen Karakus, Alan N. Baer, Esen K. Akpek

“…Anti-CA6 was associated with increased corneal and conjunctival staining after adjusting for age, sex, and other serologic markers (HR=1.5, 95% CI=1.20-1.97, and p=0.009 and HR=1.4, 95% CI=1.04-1.76, and p=0.02, respectively). …”
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Peripheral corneal ulcers in association with rheumatic diseases by E.A. Drozdova

“…</p> <p> <b>Patients and Methods: </b>а total of 32 patients (9 men and 23 women, mean age 59.3±9.4 years) with PUK associated with RD were under surveillance. …”
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Effect Of Exercise Therapy on Lipid Profile and Oxidative Stress Indicators in Patients with Type 2 Diabetes by Madeeha Jadoon, Shazia Zeb, Sajid Razaq, Munazza Khan, Muhammad Shoaib, Sara Mariyum

“…Criteria for patient selection were a T2DM duration of at least one year and patients aged between 28-45 years with or without consent to enrol for the study. …”
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Outcomes of total hip replacement in adults with septic arthritis of the native hip joint: A systematic review by Teddy Cheong, Surya Varma Selvakumar, Ryan Kwang Jin Goh, Ing How Moo

“…Results Against the relevant criteria, seven studies (six case series, one cohort study) involving 1243 patients were included. The patients aged from 18 to 78 years old. The reinfection rate ranged from 0 to 22.8%, with a mean rate of 19.6%. …”
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