Transcriptional activity of repair, apoptosis and cell cycle genes (TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) in chronically exposed perso... by V. S. Nikiforov, E. A. Blinova, A. I. Kotikova, A. V. Akleyev

“…The study was performed more than 60 years after the onset of exposure, the average age of exposed persons was 68±0.6 years (55–86 years). …”
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Problems of healing chronic wounds by N. M. Babenko, O. B. Litvinova, S. B. Pavlov, M. V. Kumechko, V. V. Komarchuk

“…Modern scientists are actively discussing the problems of wound healing, researching factors influencing the reparative process, including the high prevalence of chronic wounds, diagnosis and treatment of wound infections, age of patients, and state of immunity. In the case of systemic diseases, such as diabetes, cardiovascular pathology, etc., there is a violation of microcirculation, and as a result, there are violations of the phasing of reparative processes at the cellular level. …”
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Determination of the kidney stone composition using infrared spectroscopy in Iran at a national referral center during 2019–2023 by Abbas Basiri, Azin Tahvildari, Mohammad Naji, Pardis Ziaeefar, Amir H. Kashi

“…The percentage of UA stones increased with age as it was 11.1% in children, 42.7% in adults, and 83.3% in geriatric patients (p<0.001). …”
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Understanding the experience of the mothers’ ability to take care of their preterm infants related to in-hospital and post-discharge: a qualitative content analysis by Saleheh Tajalli, Soroor Parvizy, Abbas Ebadi, Fateme Zamaniashtiani, Carole Kenner

“…Eleven mothers, two fathers, two grandmothers, one neonatal nurse, and two neonatologists with a mean age of 36.05 ± 10.88 years were selected using purposeful and snowballing sampling in Tehran, Iran. …”
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Multi-target gene therapy AUP1602-C to improve healing and quality of life for diabetic foot ulcer patients: a phase I, open-label, dose-finding study by Christoph Schindler, Jacek Mikosiński, Pawel Mikosiński, Hanna-Riikka Kärkkäinen, Mirka Sanio, Jere Kurkipuro, Igor Mierau, Wesley Smith, Aki Vartiainen, Laurent Décory, Dirk Weber, Thomas Wirth, Juha Yrjänheikki, Sebastian Schellong, Haritha Samaranayake

“…Results: In total, 16 patients aged 53–80 years were included, 3 each in the safety and low dose, 4 in the medium dose, and 6 in the high-dose cohort. …”
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Atherogenic index of plasma and cardiovascular disease risk in cardiovascular-kidney-metabolic syndrome stage 1 to 3: a longitudinal study by Yu Zhang, Yue Song, Yinfei Lu, Tao Liu, Ping Yin

“…Restricted cubic spline regression indicated the relationship between cumulative AIP and CVD risk is linear (P for nonlinear = 0.3377).ConclusionsIn middle-aged and elderly individuals with CKM syndrome, higher cumulative AIP and poorer AIP control were associated with an elevated incidence of CVD. …”
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Personal and behavioural factors that influence physical activity in women living with metastatic breast cancer: a qualitative interview study by Mark Liu, Sharon Kilbreath, Jasmine Yee, Jane Beith, Justin McNab, Elizabeth Dylke

“…Results Twenty-three women completed the interview, with a median age of 60 years (IQR: 20) and median time since metastatic diagnosis of 3.3 years (IQR: 3.0). …”
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Biocementation Influence on Flexural Strength and Chloride Ingress by Lysinibacillus sphaericus and Bacillus megaterium in Mortar Structures by Daniel Karanja Mutitu, Jackson Muthengia Wachira, Romano Mwirichia, Joseph Karanja Thiong’o, Onesmus Mulwa Munyao, Muriithi Genson

“…Mortars prepared and cured using bacterial solution across all curing ages exhibited the highest flexural strength as well as the highest percent flexural strength gain. …”
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Correlation between selenium levels and selenoproteins expression in idiopathic generalized epilepsy: a study from Karachi by Hareem Nisar, Rafat Amin, Sadaf Khan, Tehseen Fatima, Qamar-Un-Nisa, Jawwad-Us-Salam

“…Methods Serum selenium levels of 30 patients with idiopathic generalized epilepsy and their age and gender matched 30 healthy controls were measured. …”
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Prenatal exposure to polycyclic aromatic hydrocarbons and blood pressure in the early life of children by Xiaodong Chen, Lingling Dong, Lina Yang, Yan Yang, Liyu Yang, Sijia Han

“…This cohort study investigates the association between prenatal exposure to PAHs and blood pressure in children aged 4–6 years. Conducted in Shenyang, China, the study includes 5642 children whose mothers provided urine samples in the third trimester, which were analyzed for PAH metabolites. …”
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Physical activity pattern and its influencing factors among patients with inflammatory bowel disease in East China by Ying Zhou, Feng Xu, Liyan Xu, Huiwei Liu, Xie Zhang

“…Objective To investigate the current level of physical activity (PA) and its influencing factors among patients with inflammatory bowel disease (IBD) in East China.Design Cross-sectional study.Setting Questionnaire survey recruiting from six tertiary referral hospitals in East China between October and December 2023.Participants Patients with Crohn’s disease (CD) or ulcerative colitis (UC) aged 18–65 years without conditions limiting PA engagement.Primary and secondary outcome measures Primary outcomes comprised total PA, PA levels and sedentary time over 1 week. …”
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Analysis of health expenditures in China from 2000 to 2019 compared with the world and upper-middle-income countries by Xindian Zeng, Xindian Zeng, Lijie Chen, Lu Chen

“…The government should continue to optimize the financing structure of THE, increase GHE, encourage social capital investment, decrease the proportion of OOPHE, diversify financing and reimbursement policies to promote hierarchical medical system, promote health management for an aging population, and formulate health expenditure plans for public health emergencies.…”
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Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared... by Simon Gilbody, Caroline Fairhurst, Catherine Hewitt, Dean McMillan, Carolyn Chew-Graham, Della Bailey, David Ekers, Steve Parrott, Elizabeth Littlewood, Peter Coventry, Han-I Wang, Kalpita Baird

“…Behavioural activation (BA) shows promise as a remote intervention for depression during isolation, but its cost-effectiveness for depressed, socially isolated older adults remains uncertain.Objective This study aimed to assess the cost-utility of BA versus usual care for older adults with depression and MLTCs during COVID-19 restrictions.Methods A randomised controlled trial recruited and randomised individuals aged 65 and over with depressive symptoms and MLTC (n=435) to either the BA intervention or usual care. …”
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Management Modalities of Mandible Fracture and Dental Trauma in Pediatric Patients During Mixed Dentition Phase: A Series of Case Study by Lomtu Ronrang, Alice Lyngdoh

“…More importantly, most of the time, children are under the care of their parents till they reach an age of maturity. One more thing that everyone believes even today is the elasticity nature of their bones as well as their body weight during their growing stage. …”
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Antecedents to aggression and the use of coercive measures in inpatient mental health settings: a scoping review protocol by Johan Siqveland, Mette Senneseth, Njål Herman E Sterri, Øyvind Lockertsen, Tonje Lossius Husum, Veronica Lockertsen

“…This review seeks to address this gap by systematically mapping the evidence of these antecedents and exploring their relationship, providing a foundation for future research.Inclusion criteria Studies included were those published from 2014 to the present in the English language, focusing on either adult mental health inpatients or mental healthcare professionals aged 18 years or older involved in episodes of aggression or exposure to coercive measures in both acute and long-term inpatient mental health settings. …”
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Predictors of non-response to successive waves of surveys in the Japan Environment and Children’s Study during the 3-year postpartum period: a longitudinal cohort study by Mika Kigawa, Akiko Tsuchida, Tomomi Tanaka, Kei Hamazaki, Yuichi Adachi, Hidekuni Inadera, Kenta Matsumura, Haruka Kasamatsu

“…The strength of the impact of related factors and the prediction of response status were examined and compared using binominal logistic regression analysis.Results For all six follow-up questionnaire surveys, higher maternal age was strongly associated with providing a response. …”
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Comparing Rotational Stability of Clareon and Eyhance Toric IOLs in a Real-World Setting by Connell B, LaHood B

“…IOL rotational measurements were recorded at each interval.Results: The study included 187 patients (median age: 74 for Clareon, 79 for Eyhance, p = 0.004). …”
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The Role of Microelements of Lumbar Disc Degeneration in Patients Undergoing Lumbar Spine Surgery by Sadiq R. Karkush, Manal K. Rasheed, Ali T. Abdul Wahid, Ahmed R. Majeed

“…The study included 120 participants ranging in age from 18 to 70 years. Sixty participants underwent lumbar spine surgery and were diagnosed using X-rays or MRI scans. …”
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Transgenerational effect of prenatal stress on behavior and lipid peroxidation in brain structures of female rats during the estral cycle by A. V. Vyushina, A. V. Pritvorova, S. G. Pivina, N. E. Ordyan

“…The females of the F2 generation born from these couples were selected into four experimental groups in accordance with the family group. At the age of 3 months, behavior of rats was studied in the “open field” test in two stages of the ovarian cycle – estrus and diestrus. …”
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Exploring the gender difference in type 2 diabetes incidence in a Swiss cohort using latent class analysis: an intersectional approach by Julien Vaucher, Michael Amiguet, Carole Clair, Joelle Schwarz, Jeanne Marie Barbier, Aurélie M Lasserre

“…The aim of this study was to highlight the intersectional social position of the participants and disentangle its role from administrative sex in predicting the development of type 2 diabetes.Methods Using CoLaus|PsyCoLaus study, a Swiss single-centre prospective cohort initiated in 2003 and including 6733 participants (age 35–75 years; 54% women) at baseline, we conducted latent class analyses using gender-related variables (eg, risk-taking behaviours, gender roles represented by employment status, etc) and socioeconomic determinants at baseline (2003–2006) to construct intersectional classes and we tested their association with the development of type 2 diabetes at follow-up (2018–2021).Results Of the 6733 participants enrolled at baseline, 3409 were included in our analyses (50.6%). …”
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