Psychosocial distress, perceived need and utilization of psycho- social support services in patients in the early phase after the first cancer diagnosis by Hannah Zingler, Diana Steinmann, Jochen Ernst, Ute Goerling, Myriel Hermann, Beate Hornemann, Anja Mehnert-Theuerkauf, Tanja Zimmermann

“…Results Of 1,003 eligible patients who completed the questionnaire (53.0% men, mean age 60.3 years) 39.7% (n = 390) showed above-threshold psychosocial stress (DT: scores ≥ 5) and 21% (n = 207) indicated a perceived need for psycho- social support. 13.5% (n = 136) showed both, psychosocial distress and perceived need for psycho- social support. 15.2% (n = 150) out of all participating patients used psycho-oncology service, 60.7% (n = 597) were willing to accept such an offer. …”
Get full text

Optical Coherence Tomography May Help Distinguish Glaucoma from Suprasellar Tumor-Associated Optic Disc by Michael Mimouni, Hadas Stiebel-Kalish, Irena Serov, Gabriel Chodick, Mohammad Zbedat, Dan D. Gaton

“…Both groups were similar in terms of gender and age (P>0.05). The glaucoma group had a borderline greater total RNFL thickness (74.2 μm versus 62.8 μm, P=0.07), disc area (2.70 mm2 versus 2.16 mm2, P=0.004), and cup volume (0.20 mm3 versus 0.08 mm3, P=0.02). …”
Get full text

After Effect of Electroacupuncture at Jiaji Acupoint on the Protein Expression of P2X4, P2X7 in Chronic Constriction Injury Rats by Hui'e CHEN, Mingyu HUANG, Wenying YU, Dong LIN, Lili LIN

“…The after effect can be extended for one hour or more than one hour, with a certain regularity of aging.…”
Get full text

Multiple Sessions of Antimicrobial Photodynamic Therapy Improve Periodontal Outcomes in Patients with Down Syndrome: A 12-Month Randomized Clinical Trial by Rafael Ferreira, Sebastião Luiz Aguiar Greghi, Adriana Campos Passanezi Sant’Ana, Mariana Schutzer Ragghianti Zangrando, Carla Andreotti Damante

“…<b>Background/Objectives:</b> Individuals with Down syndrome (DS) often present with severe periodontal disease at a young age. Adjuvant treatments to scaling and root planing (SRP), such as antimicrobial photodynamic therapy (aPDT), may benefit this population. …”
Get full text

Identification of ketamine and norketamine in dried bloodstains on crime-scene surfaces by Risha Jasmine Nathan, Babajide Okeleye, Rabiu Abdullahi, Waliyu Oyebode

“…The present study has analysed the stability of ketamine and norketamine in DBS aged on common crime scene surfaces under various storage temperatures. …”
Get full text

Single-nucleotide variant rs1800139 of the LRP1 gene as a factor in the development of obesity in children by O.Ye. Abaturov, A.O. Nikulina

“…Materials and methods. 253 obese children aged 6-18 years were examined. The main group (n=153) was made up of children with metabolically unhealthy obesity (MUO) according to IDEFICS 2014 criteria. …”
Get full text

Construction and validation of risk prediction models for renal replacement therapy in patients with acute pancreatitis by Fei Zuo, Lei Zhong, Jie Min, Jinyu Zhang, Longping Yao

“…The optimal model was visualized and clarified using SHapley Additive exPlanations (SHAP) and presented as a nomogram. Results The mean age of the cohort was 59.17 years, with an average Acute Physiology and Chronic Health Evaluation II (APACHE II) score of 17.55. …”
Get full text

Prognostic Nutritional Index Predicts Early Mortality in Diffuse Large B-cell Lymphoma by Erman OZTURK, Tayfun ELIBOL, Emrah KILICASLAN, Beyza KABAYUKA, Işıl ERDOGAN OZUNAL

“…Results: One hundred and ten patients were included, the median age was 63 years and the median follow-up period was 25 months. …”
Get full text

Is Weight Loss the Main Driver for A1C Improvement by Glucagon‐Like Peptide 1 (GLP‐1) Receptor Agonists? A 2.5‐Year Analysis in Real‐World Clinical Practice by Marwa Al‐Badri, Shilton Dhaver, Osama Hamdy

“…Baseline characteristics included an average age of 61.8 ± 11.9 years, 51.5% female, diabetes duration of 12.9 ± 8.3 years, weight of 103.1 ± 20.7 kg, BMI of 35.7 ± 7.5 kg/m2, and A1C of 8.2% ± 1.5%. …”
Get full text

Availability and accessibility of cytotoxic medicines in the WHO model list of essential medicines for childhood cancer in low and lower-middle- income countries: a systematic revi... by Maheeka Seneviwickrama, Sashini Shehana Denagamagei, Surangi Jayakody, Sanjeeva Gunasekera, Guwani Liyanage

“…Children under 19 years of age living in LLMICs diagnosed with any malignancy were the client group. …”
Get full text

Analysis of early morphological and functional perivulnar changes in the mucosa of the cecum after suturing with different surgical threads by S.M. Bilash, O.M. Pronina, I.V. Ksyonz, M.M. Koptev, Ya.O. Oliinichenko, B.S. Kononov

“…The study was conducted on 25 rabbits aged 8-10 months in compliance with all bioethical standards and recommendations. …”
Get full text

Cancer incidence and the influence of immunosuppressive agents in Korean patients with systemic lupus erythematosus: a retrospective cohort study by Soo-Kyung Cho, Jung-Yong Han, Yena Jeon, Seung-Hun You, Sun-Young Jung, Eun Jin Jang, Yoon-Kyoung Sung

“…Results A total of 10,013 predominantly female (91%) Korean SLE patients with a mean age of 36.9 ± 15.2 years were included. During a follow-up of 62,268.5 PYs, 368 patients developed cancer. …”
Get full text

Persistent Mortality Risk From Device-related Healthcare-associated Infection in Kidney Transplant Recipients Despite Multifaceted Interventions Action Calls for a Zero-tolerance P... by Maria Bethânia Peruzzo, MD, Luana Oliveira Calegari, MSc, Renato Demarchi Foresto, MD, PhD, Helio Tedesco-Silva, MD, PhD, José Medina Pestana, MD, PhD, Lúcio Requião-Moura, MD, PhD

“…Additional variables associated with increased risk of death included age (HR, 1.03; P < 0.001), baseline immunosuppression (HR based on mycophenolate versus others 0.74; P = 0.02), time since transplantation (HR, 1.003; P < 0.001), platelet count at ICU admission (HR, 0.998; P < 0.001), and sepsis as the reason for ICU admission (HR, 1.67; P < 0.001). …”
Get full text

The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction by Ahmet KARADUMAN, Cemalettin YILMAZ, Mustafa Ferhat KETEN, Ismail BALABAN, Zeynep Esra GUNER, Mehmet CELIK

“…Results: There were 295 patients (23.1% female, 76.9% male) included in the research, with an average age being 61.2+-10.9 years, and the mean SYNTAX score being 7.3+-10.4 (range: 0-40). …”
Get full text

Chest CT Scan Features to Predict COVID-19 Patients’ Outcome and Survival by Mohammad-Mehdi Mehrabi Nejad, Aminreza Abkhoo, Faeze Salahshour, Mohammadreza Salehi, Masoumeh Gity, Hamidreza Komaki, Shahriar Kolahi

“…After evaluating 384 cases, a total of 186 patients (93 in each group) were admitted to the studied setting, consisting of 126 (67.7%) male patients with a mean age of 60.4 ± 13.6 years. The PI score and PI density index in the case vs. the control group were on average 8.9 ± 4.5 vs. 10.7 ± 4.4 (p value: 0.001) and 2.0 ± 0.7 vs. 2.6 ± 0.8 (p value: 0.01), respectively. …”
Get full text

810-nm Photobiomodulation Evokes Glutamate Release in Normal and Rotenone-Dysfunctional Cortical Nerve Terminals by Modulating Mitochondrial Energy Metabolism by Silvia Ravera, Elisa Farsetti, Guido Maura, Manuela Marcoli, Matteo Bozzo, Chiara Cervetto, Andrea Amaroli

“…The dysfunction of mitochondria, the primary source of cellular energy and producer of reactive oxygen species (ROS), is associated with brain aging and neurodegenerative diseases. Scientific evidence indicates that light in the visible and near-infrared spectrum can modulate mitochondrial activity, a phenomenon known in medicine as photobiomodulation therapy (PBM-t). …”
Get full text

Construction of an Interpretable Model of the Risk of Post-Traumatic Brain Infarction Based on Machine Learning Algorithms: A Retrospective Study by Li S, Li H, Wu B, Pan R, Liu Y, Wang J, Wei D, Gao H

“…The interpretations of the ML models’ predictions were provided by SHAP values.Results: Key predictors included age, bilateral brain contusions, platelet count, uric acid, glucose, traumatic subarachnoid hemorrhage, and surgical treatment. …”
Get full text

The Effect of Chicory Consumption on Oxidative Stress Indices of the Kidney Tissue in Female Wistar Rats Consuming Testosterone Enanthate during eight weeks Resistance Training by Khadijeh Molaei, Sanaz Mirzayan Shanjani, Ali Gorzi, Yaser Kazemzadeh, Abdolali Banaeifar

“…Materials and Methods: 22 female wistar rats aged 8 weeks and weighing 208.22±14.17 grams were provided from Pasteur Institute (Iran). …”
Get full text

Socio-Demographic and Preoperative Clinical Factors Associated With 5-Year Weight Trajectories After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy by Sahil Patel, MD, Chen Jiang, PhD, Brandon Cowan, MD, Jie Yin, MS, Catherine Schaefer, PhD, Sanjoy Dutta, MD, Rouzbeh Mostaedi, MD, Hélène Choquet, PhD

“…We then evaluated whether age, sex, race/ethnicity, neighborhood deprivation index and preoperative body mass index (BMI)/weight loss, diabetes, hypertension, and sleep apnea contributed to postoperative %TBWL using logistic regression models. …”
Get full text

Healthcare utilization and costs for patients with Parkinson’s disease in Taiwan by Kuan-Chen Chen, Li-Jung Elizabeth Ku, Ya-Hui Hu, Yu Sun, Alexis Elbaz, Pei-Chen Lee

“…We performed analyses stratified by PD severity and also by age, gender, and duration of follow-up. Results We identified 50,290 PD cases and 201,153 non-PD subjects. …”
Get full text