Can the adherence to quality of care indicators for early rheumatoid arthritis in clinical practice reduce risk of hospitalisation? Retrospective cohort study based on the Record L... by Carlo Alberto Scirè, Antonella Zambon, Greta Carrara, Anna Zanetti, Lisa Argnani

“…Objective To describe the adherence to quality of care indicators in early rheumatoid arthritis (RA) and to evaluate its impact on the risk of hospitalisation in a real-world setting.Design Retrospective cohort study.Setting Patients with early-onset RA identified from healthcare regional administrative databases by means of a validated algorithm between 2006 and 2012 in the Lombardy region (Italy).Participants The study cohort included 14 203 early-onset RA (71% female, mean age 60 years).Outcome measures For each patient, a summary adherence score was calculated starting from the compliance to six quality indicators: (1–2) methotrexate or sulfasalazine or leflunomide with/without glucocorticoids, (3–4) other disease-modifying antirheumatic drugs (DMARDs) with/without glucocorticoids, (5) early interruption of glucocorticoids, (6) early clinical assessment.The relationship between low, intermediate and high categories of the summary score and the 12-month risk of hospitalisation for all causes and for RA was assessed.Results During a follow-up of 1 year, 2609 hospitalisations occurred, of which 704 were for RA (main or secondary diagnosis) and 252 primarily for RA. …”
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Effect of Isoniazid Preventive Therapy on the Incidence of Tuberculosis among Seropositive Children Attending HIV/AIDS Care in Two General Hospitals, Northwest Ethiopia, 2021 by Fassikaw Kebede, Birhanu Kebede, Tsehay Kebede, Melaku Agmasu

“…Missed IPT (AHR = 7.45, 95% CI: 2.96, 18.74, P<0.001), missed cotrimoxazole preventive therapy (CPT) (AHR = 2.4, 95% CI: 1.84–4.74, P<0.022), age ≥ 11 years (AHR = 4.2, 95% CI: 1.04–7.03, P<0.048), MUAC ≤ 11.5 cm (AHR = 4.36, 95% CI: 1.97–9.97, P<0.001), WHO stages III and IV (AHR = 2.04, 95% CI: 1.12–3.74, P<0.022), and CD4 count ≤100 cells/μl (AHR = 3.96, 95% CI: 1.52–10.34, P<0.005) were significantly associated with TB incidence. …”
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Characterization of Cannabis usage in individuals with non-cancer chronic pain in the state of Maine using the Behavioral Risk Factor Surveillance System (BRFSS) by Rachel Bordonaro, Elizabeth N. Bean, Ling Cao

“…Results We observed an increase of high-frequency users (21–30 days/last 30 days) and reduction of non-users for both sexes from 2017 to 2020, which was significant in controls (p < 0.05). The average age of cannabis users was lower than non-users, regardless of sex or pain status (p < 0.05). …”
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Occult Renal Calcifications in Patients with Normocalcemic Primary Hyperparathyroidism and Their Association with the Parathyroid Hormone-Vitamin D Axis by Fernanda Victor, Alyne Layane Pereira Lemos, Anna Mirella de Holanda Ribas, Leonardo Bandeira, José Henrique Pimentel, Luiz Otávio de Andrade Damázio, Francisco Bandeira

“…The patients had a mean age of 67.97 ± 10.45 years, predominantly postmenopausal women (88.2%); serum PTH, 119.67 ± 64.44 pg/mL; 25(OH)D, 39.00 ± 8.88 ng/dL; 1.25(OH))2D, 74.53 ± 26.37 pg/mL; corrected serum calcium, 9.34 ± 0.62 mg/dL; and 24-hour urinary calcium, 134.87 ± 79.68 mg/day. …”
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Structural validity and internal consistency of the Patient Centred Assessment Method in a primary care setting in a Japanese island area: a cross-sectional study by Masato Matsushima, Shuhei Yoshida, Rieko Mutai, Yoshifumi Sugiyama, Ryoko Horiguchi, Hisashi Yoshimoto

“…Objectives The objective of this study was to examine the structural validity and internal consistency of the original English version of the Patient Centred Assessment Method (PCAM) in a primary care setting in a Japanese island area.Design Cross-sectional study.Setting A clinic on a remote island in Okinawa, Japan, that provides general outpatient and 24-hour emergency services.Participants This study included 355 patients who visited Tarama Clinic from 1 April 2018 to 30 June 2018, were aged ≥20 years, lived in Tarama Village and had decision-making capacity.Main outcome measures Patient complexity scored by the PCAM.Results The mean (SD) PCAM score was 21.4 (5.7). …”
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Methylation and Expression of Retinoblastoma and Transforming Growth Factor-β1 Genes in Epstein-Barr Virus-Associated and -Negative Gastric Carcinomas by Xia Liu, Xiuming Tang, Shaoyan Zhang, Yun Wang, Xiaofeng Wang, Chengquan Zhao, Bing Luo

“…RB methylation, loss expression of RB, and TGF-β1 expression were significantly associated with tumor invasion and lymph node metastasis (P<0.05), but was not associated with sex, age, histological subtype (differentiation status) and tumor location. …”
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Exploring the Functional Brain Activity of Motor Control of Abdominal Muscle Associated with Voluntary Voiding Based on Functional Near-Infrared Spectroscopy by SHI Yinshuang, WANG Menghuan, PAN Yingying, LIN Feng

“…ObjectiveThe contractions of abdominal muscle during voluntary urination is a motor control task, Which aims to explore the central activity characteristics of this action with functional near-infrared spectroscopy (fNIRS).MethodsA total of 19 healthy subjects aged 18 years or older were recruited to undergo fNIRS testing twice, performing repetitive abdominal muscle contractions in the no-urine and strong-urine states. …”
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Association between Visual Acuity and Retinal Layer Metrics in Diabetics with and without Macular Edema by LakshmiPriya Rangaraju, Xuejuan Jiang, J. Jason McAnany, Michael R. Tan, Justin Wanek, Norman P. Blair, Jennifer I. Lim, Mahnaz Shahidi

“…The associations among VA and retinal layer metrics were determined by multivariate linear regressions after adjusting for covariates (age, sex, race, HbA1c, diabetes type, and duration) and correcting for multiple comparisons. …”
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Assessment of programmed cell death 1 and its programmed cell death ligand 1 levels in vitiligo by Hanan R. Nada, Ahmed Mourad, Laila A. Rashed, Ghada M. El-Hanafy, Nermeen M.A. Abdallah, Mohamed M. Abdelhady

“…Patients and methods A total of 30 vitiliginous patients and 30 age and sex-matched controls were included. Full history and clinical examination were done and ELISA measured tissue levels of PD-1 and PD-L1 from lesional and nonlesional biopsies. …”
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Perspectives towards training approaches to skill achievement in swimming athletes: mixed methods by Ari Tri Fitrianto, Hegen Dadang Prayoga, Oddie Barnanda Rizky, Nina Sutresna, Albadi Sinulingga, Syahruddin Syahruddin, Trisnar Adi Prabowo

“…The sample consisted of ten coaches aged 35-55 years, with an average of 17.8±7.8 years of coaching experience. …”
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Evaluating the therapeutic effect of different forms of silymarin on liver status and expression of some genes involved in fat metabolism, antioxidants and anti‐inflammatory in old... by Samira Faryadi, Ardashir Sheikhahmadi, Ayoub Farhadi, Himan Nourbakhsh

“…Methods The experiment was conducted using 70 Lohmann LSL‐Lite hens at 80 weeks of age with 7 treatments each with 10 replicates. Treatments included: (1) control diet without silymarin, (2) daily intake of 100 mg silymarin powder/kg body weight (BW) (PSM100), (3) daily intake of 200 mg silymarin powder/kg BW (PSM200), (4) daily intake of 100 mg nano‐silymarin/kg BW (NSM100), (5) daily intake of 200 mg nano‐silymarin/kg BW (NSM200), (6) daily intake of 100 mg lecithinized silymarin/kg BW (LSM100) and (7) daily intake of 200 mg lecithinized silymarin/kg BW (LSM200). …”
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Digital sleep phenotype and wrist actigraphy in individuals at clinical high risk for psychosis and people with schizophrenia spectrum disorders: a systematic review and meta-analy... by Andrea Cipriani, Edoardo Giuseppe Ostinelli, John Torous, Paolo Brambilla, Philip McGuire, Dominic Oliver, Rosario Aronica, Charlotte Austin

“…Factors such as antipsychotic medications (pseudo-R²=88.14%), age (38.89%) and gender (26.29%) partially explained the heterogeneity between subgroups. …”
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Telomere Length and Oxidative Damage in Children and Adolescents with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis by Leping Ma, Cui Liu, Ran Song, Yeping Qian, Feng Zhang

“…Telomere erosion caused by oxidative stress is a common consequence in age-related diseases. However, whether telomere length (TL) and oxidative indicators are significantly changed in ASD patients compared with controls remains controversial. …”
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Nursing-Related Barriers to Children’s Pain Management at Selected Hospitals in Ghana: A Descriptive Qualitative Study by Abigail Kusi Amponsah, Evans Frimpong Kyei, John Bright Agyemang, Hanson Boakye, Joana Kyei-Dompim, Collins Kwadwo Ahoto, Evans Oduro

“…NVivo 12 plus software guided data management and analyses. The mean age of participating nurses was 30 years, with majority being females (n = 24). …”
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Patient perspectives on telemedicine during the COVID-19 pandemic: a mixed-methods community-based study by Marije J. Splinter, M. Kamran Ikram, Charles W. Helsper, Patrick J.E. Bindels, Evelien I.T. de Schepper, Silvan Licher

“…Results 4514 participants completed the questionnaire (response rate 77.0%, 58.7% women, mean age 70.8 ± 10.5 years). 1103 participants (24.4%) reported having had experience with virtual consultations. …”
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Validation of the shortest version of the eating attitude test (EAT-7) as a screening tool for disordered eating in patients with first-episode schizophrenia by Feten Fekih-Romdhane, Youssef Boukadida, Majda Cheour, Souheil Hallit

“…The study took place between January and June 2024, and involved clinically-stabilized outpatients with schizophrenia who have had < 3 months of treatment with antipsychotics (N = 112; mean age of 24.44 ± 5.41 years). Results In terms of factor analysis, the EAT-7 presented a one-dimensional structure. …”
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Capecitabine enhances sensitivity to oxaliplatin in advanced gastric cancer and the effects on patients’ FOXP1 and GGT levels by Xinyu Guo, Yi Liu

“…The 1-year survival rate of 152 patients with gastric cancer was 84.87% (129/152) and the 3-year survival rate was 63.17% (96/152). Age, tumor-node-metastasis (TNM) stage, lymph node metastasis, chemotherapy regimen, FOXP1, and GGT levels were important factors in determining OS. …”
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Shaping the future of primary healthcare: Factors influencing medical students’ preference for family medicine specialty in Qatar by Maryam A. Al-Rashid, Muna T Abed Alah, Areej S. Al-Hamad, Michail Nomikos, Marwan F. Abu Hijleh

“…RESULTS: A total of 262 students completed the survey with age ranging between 17-24 years (Mean=20, SD=1.7 years); majority (68.3%) were females and 54.4% were non-Qatari. …”
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Association of Intensive Endoscopic Burden with Esophageal Cancer Detection: A Nationwide Cohort Study by Yeunji Lee, Eunyoung Lee, Bumhee Park, Gil Ho Lee, Sun Gyo Lim, Sung Jae Shin, Choong-Kyun Noh, Kee Myung Lee

“…Methods: This retrospective population-based study used the Korean National Cancer Screening Program database, comprising 32,774,742 males and females aged ≥40 years between 2015 and 2019. Negative binomial regression model and least-squares mean evaluation were used to assess the association between month of the year and EC detection rates. …”
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Association of Vitamin D Deficiency and Newly Diagnosed Pulmonary Tuberculosis by Vijay Jaimni, Barkur Ananthakrishna Shasty, Sharath P. Madhyastha, Ganesh V. Shetty, Raviraja V. Acharya, Ragini Bekur, Akhila Doddamani

“…A case-control study was conducted in a tertiary care hospital from 2014 to 2016, including 50 adult newly diagnosed sputum positive pulmonary tuberculosis patients as cases and 50 age and sex-matched healthy participants as control groups. …”
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