Incidence of Malignancies and the Association with Biological Disease-Modifying Antirheumatic Drugs in Japanese Patients with Rheumatoid Arthritis: A Time-Dependent Analysis from t... by Masayoshi Harigai, Eiichi Tanaka, Eisuke Inoue, Ryoko Sakai, Naohiro Sugitani, Shigeyuki Toyoizumi, Naonobu Sugiyama, Hisashi Yamanaka

“…Using patient registry data, we determined malignancy risk, stratified by bDMARD use, among Japanese patients with RA versus the Japanese general population and investigated whether bDMARD use is a time-dependent risk factor for the development of malignancy. Methods Patients aged ≥ 18 years with ≥ 2 data entries of RA in the IORRA (Institute of Rheumatology, Rheumatoid Arthritis) patient registry, enrolled from January 2013–December 2018, were identified (‘All RA’ cohort). …”
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Geriatric nutritional risk index as a predictor of 30-day and 365-day mortality in patients with acute myocardial infarction: a retrospective cohort study using the MIMIC-IV databa... by Xiaolong Zheng, Xiaolong Zheng, Xin Zheng, Xin Zheng, Changgui Zhang, Minghua Liu

“…Subgroup analyses were conducted based on gender, hypertension, diabetes, stroke, hyperlipidemia, chronic obstructive pulmonary disease, and age. A mediation study was conducted to investigate the impact of lymphocytes on the association between GNRI and mortality.ResultsIn an overall sample of 895 patients, an elevated GNRI correlated with reduced 30-day (HR = 0.937, 95% CI: 0.917–0.957, p < 0.001) and 365-day mortality (HR = 0.937, 95% CI: 0.923–0.950, p < 0.001). …”
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Impact of immunosuppressive regimens on antibody response after COVID-19 vaccination among Thai kidney transplant recipients by Nuttasith Larpparisuth, Kritsada Pongsakornkullachart, Nartsiri Ratchawang, Attapong Vongwiwatana, Peenida Skulratanasak

“…Results: Between October 2021 and January 2022, 139 KTRs with a median time of 55 months (IQR, 29–102 months), were enrolled. The mean age was 49.1 ± 11.3 years and 64.7 % were men. Seroconversion of anti-RBD was found in 72 patients (51.8 %). …”
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Reactivity in cell culture medium and in vitro anticancer activity of 3,5-di-tert-butylcatechol: link to metal-catechol interactions by Aviva Levina, Debbie C. Crans, Peter A. Lay

“…The reactivities and biology activities of a sterically hindered model catechol compound, 3,5-di-tert-butylcatechol (dtbH2) and its oxidation product 3,5-di-tert-butyl-o-quinone (dtbQ), were studied in cell culture medium to understand better the medicinal roles of this class of molecules.MethodsAnti-proliferative activities of dtbH2 and dtbQ in fresh and aged solutions of the molecules were studied in two common human cancer cell lines, T98G (glioblastoma) and A549 (lung carcinoma). …”
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La stips des Alpes à la Méditerranée : interpréter la présence des monnaies dans les sanctuaires d’époque romaine by Raphaël Golosetti

“…This is extremely interesting as it signifies the end of the practice of coin perforation, which was well identified for the south of Gaul in the Iron Age, during the Roman period. Finally, bibliographic data emphasize the constant values of the deposited coins, the most common coins, or often, but not exclusively, those of the least value. …”
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Association of Light’s Criteria with Pleural Fluid Procalcitonin Levels and Ultrasound Thorax with its Impact on the Management of Pleural Effusion: A Cross-sectional Study by BK Likhitha, Keertivardhan D Kulkarni, Madhav Mahawar

“…Categorical variables between the two groups (exudative group and transudative group) were compared using the Chi-square/Mann-Whitney U test, with p<0.05 considered statistically significant. Results: The mean age of the study participants was 50.8±18.1 years. …”
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From Acceptance to Dependence: Exploring Influences of Smart Healthcare on Continuous Use Intention of Mobile Health Services Among Older Adults with Chronic Illnesses in China by Jiacheng Luo, Kewei Zhang, Qianghong Huang, Shan Jiang, Younghwan Pan

“…With the acceleration of the aging process in China, chronic diseases have become one of the main health threats for older adults, creating significant pressure on society and the healthcare system. …”
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Ductal Carcinoma In Situ (DCIS) Diagnosed by MRI-Guided Biopsy among BRCA1/BRCA2 Mutation Carriers by Renata Faermann, Eitan Friedman, Orit Kaidar-Person, Jonathan Weidenfeld, Malka Brodsky, Anat Shalmon, Osnat Halshtok Neiman, Michael Gotlieb, Yael Yagil, David Samoocha, Dana Madorsky Feldman, Miri Sklair-Levy

“…Results. 18/121 (15.2%) participating BRCA1 PSV carriers and 8/81 (10.1%) BRCA2 PSV-carriers who underwent MRI-guided biopsy were diagnosed with DCIS. The median age of BRCA1 carriers and BRCA2 carriers was 49.8 years and 60.6 years, respectively (p=0.55). …”
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Characteristics associated with career self-reliance behaviors of nurses working in nursing homes in Japan: A cross-sectional study by Ayako Nakayama, Junko Hoshino, Masashi Hotta, Mayuri Hashimoto, Naomi Furukawa

“…Background: With an aging global population, establishing integrated systems for long-term care is challenging in several countries. …”
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Differential effects of left DLPFC anodal and cathodal tDCS interventions on the brain in children with autism: A randomized controlled trial by Jiannan Kang, Juanmei Wu, Xinping Huang, Wenqin Mao, Xiaoli Li

“…Methods: This study recruited a total of 24 children with ASD (20 males and 4 females; mean age ± SD: 5.5 ± 1.2 years), who were randomly divided into two groups receiving either anodal or cathodal tDCS targeting the DLPFC. …”
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Collecting Real-World Data via an In-Home Smart Medication Dispenser: Longitudinal Observational Study of Survey Panel Persistency, Response Rates, and Psychometric Properties by Benjamin Ogorek, Thomas Rhoads, Erica Smith

“…For validity, we measured the association between the falls question and known factors influencing fall risk: age, biological sex, quality of life, physical and emotional health, and use of selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors, using repeated-measures regression for covariates and Kendall τ for concomitant spencer questions. …”
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Hubungan Tumor Necrosis Factor-Alfa (Tnf-A) dengan Kadar Hemoglobin dan Parasitemia pada Infeksi Malaria Falciparum by Lili Irawati

“…This study consisted of twenty-five falciparum malaria patients as samples. Age was around 14 – 60 years old. The data processing Pearsonn correlation test by computerized system and it was consider to be significant if it gets p &lt; 0.05. …”
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Safety and efficacy of intravenous thrombolysis: a systematic review and meta-analysis of 93,057 minor stroke patients by Mostafa Hossam El Din Moawad, Talal Salem, Anas Alaaeldin, Youssef Elaraby, Peter D. Awad, Amr Ahmed Khalifa, Ahmed El Naggar, Khaled Ashraf Mohamed, Mohamed Elhalal, Mostafa Badr, Ramy Abdelnaby

“…Results A total of 21 articles with 93,057 patients with MIS were included. The mean age of the participants ranged from 62.3 to 79.6. …”
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Impact of re-operation on progression-free survival in patients with recurrent GBM: Experience in a tertiary referral center. by Houssein Darwish, Tasnim Diab, Sarah Kawtharani, Mounir Barake, Bader Ali, Nagham Ramadan, Hiba Fadlallah, Jeannot Kekedjian, Marwan Najjar, Hazem I Assi

“…Time to progression and time to death were analyzed using the Kaplan-Meier curve, with differences between groups assessed by the log-rank test.<h4>Results</h4>Age categorization (≤50 vs. >50 years) and gender distribution did not significantly impact reoperation likelihood (p = 0.306 and p = 0.616, respectively). …”
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Comparison of clinical efficacy of different internal fixation methods in older adult patients with osteoporotic fractures of proximal humerus by Zongpu Wang, Tienan Wang, Song Qin, Jianchuan Wang, Jianchuan Wang

“…The patients comprised 18 males and 30 females, with a mean age of (68.6 ± 5.8) years. The 48 patients were divided into three groups based on their treatment methods: Group A: 16 patients treated with PHILOS plate combined with calcium sulfate injection. …”
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All extern? Exploring the Impact of Social Media and Physical Activity on Adolescents’ Body Image and Interoception by Moritz Peter Engel, Mirko Schmidt

“…Methods In a within-subject design, 36 participants aged 13 to 17 will take part in a laboratory experiment consisting of two experimental conditions. …”
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Atopic Dermatitis Treatments Before and After Initiation of Ruxolitinib Cream: 6-Month Follow-Up Analysis of a US Payer Claims Database by Liu J, Desai K, Teng CC, Sturm D, Stockbower G, Patadia H, Willey V

“…This analysis describes treatment patterns before and after initiation of ruxolitinib cream among patients with AD.Patients and Methods: This retrospective, observational study used medical and pharmacy claims data from the Healthcare Integrated Research Database (HIRD®) and included adults and adolescents (aged ≥ 12 years) with an AD diagnosis, a first claim for ruxolitinib cream (index date) between October 2021 and July 2022, and continuous enrollment in a commercial or managed Medicare plan for 6 months before and after the index date. …”
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Playing hide and seek with primates: A comparative study of Theory of Mind by Aurore San‑Galli, Marie Devaine, Cinzia Trapanese, Shelly Masi, Sébastien Bouret, Jean Daunizeau

“…Further analyses are in progress to identify predictive factors (e.g. familiarity with humans, age, motivation and frustration during the game) that could explain away inter-individual differences, thus eventually revealing (or not) inter‑species differences [Authors Aurore San‑Galli and Marie Devaine contributed equally to this work].…”
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Selective micropulse individual retinal therapy in the navigation- guided treatment for central serous chorioretinopathy with parameter selection by preliminary testing by P.L. Volodin, E.V. Ivanova

“…</p> <p> <b>Patients and Methods: </b>61 patients (61 eyes) aged 36–58 with acute CSCR and transparent media were enrolled. …”
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Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance by Bogdan Batko, Slawomir Jeka, Piotr Wiland, Agnieszka Zielińska, Maria Stopińska-Polaszewska, Marcin Stajszczyk, Magdalena Kosydar-Piechna, Mary Jane Cadatal, Jose L. Rivas

“…Methods Patients with RA in ORAL Surveillance (NCT02092467), who were aged ≥ 50 years with ≥ 1 additional CV risk factor, received tofacitinib 5 or 10 mg twice daily or TNFi; 45.9% were from either Poland or North America. …”
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