Development and nutritional evaluation of pomegranate peel enriched bars. by Rameeza Abbas, Muhammad Aamir, Farhan Saeed, Amar Shankar, Jaspreet Kaur, Rutaba Nadeem, Ashish Singh Chauhan, Ali Imran, Muhammad Afzaal, Abdela Befa Kinki

“…Among the confectionary products, bars are liked by individuals of different age groups. Hence, nutritional properties of bars can be enhanced by using pomegranate peel powder. …”
Get full text

Risk of SARS-CoV-2 infection before and after the Omicron wave in a cohort of healthcare workers in Ontario, Canada by Jorge L. Martinez-Cajas, Ann Jolly, Yanping Gong, Gerald Evans, Santiago Perez-Patrigeon, Bradley Stoner, T. Hugh Guan, Beatriz Alvarado

“…We employed Poisson regression for period #1 and Cox regression for period #2 to examine associations of demographic factors (age, sex, ethnicity, migration status, income insufficiency), health factors (chronic conditions, smoking history, SARS-CoV-2 vaccination status), household factors (exposure to COVID-19), occupational factors (work role, exposure to COVID-19 patients, personal protective equipment access, aerosol-generating procedures) and community exposures (use of masks, distance, hand-washing) with SARS-CoV-2 infection. …”
Get full text

Le port antique de Chelles (Seine-et-Marne) : une course après la rivière by Yann Le Jeune, Corinne Charamond, Christian Charamond

“…The dating of the displacement is yet to be specified, but would appear to be later than or contemporary to the Roman period and was already in place in the Middle Ages.…”
Get full text

Associated adverse outcomes with tumor treating fields when combined to temozolomide versus temozolomide alone for the treatment of glioblastoma: a meta-analysis of randomized tria... by Yuanyuan Chen, Yan Chen, Hong Zhen, Danhua Lou

“…The majority of the participants were males (68.0–75.0%) with a mean age of the varying from 54.0 to 69.0 years. Results of this analysis showed that TTF in combination with temozolomide was not associated with significantly higher adverse outcomes related to blood and lymphatic system disorders (RR:0.87, 95% CI 0.30–2.48; P = 0.79), gastrointestinal disorders (RR: 0.83, 95% CI 0.14–4.72; P = 0.83), general deterioration and malaise (RR: 1.43, 95% CI 0.90–2.25; P = 0.13), infections and infestations (RR: 1.21, 95% CI 0.33–4.45; P = 0.78), injury/poison and procedural complications (RR: 1.78, 95% CI 0.88–3.61; P = 0.11), metabolic and nutritional disorders (RR: 0.61, 95% CI 0.34–1.08; P = 0.09), central nervous system disorders (RR: 1.14, 95% CI 0.89–1.46; P = 0.31), musculoskeletal and connective tissue disorders (RR: 0.99, 95% CI 0.48–2.07; P = 0.99), respiratory/thoracic/mediastinal disorders (RR: 0.85, 95% CI 0.44–1.62; P = 0.62), and psychiatric disorders (RR: 1.27, 95% CI 0.42–3.79; P = 0.67). …”
Get full text

Exploring the assessment of post-cardiac valve surgery pulmonary complication risks through the integration of wearable continuous physiological and clinical data by Lixuan Li, Yuekong Hu, Zhicheng Yang, Zeruxin Luo, Jiachen Wang, Wenqing Wang, Xiaoli Liu, Yuqiang Wang, Yong Fan, Pengming Yu, Zhengbo Zhang

“…Univariate logistic regression analysis suggested that surgical methods, age, nni_50, and min_ven_in_mean are significantly associated with the occurrence of PPCs. …”
Get full text

Utility of Pulse Oximetry Oxygen Saturation (SpO2) with Incorporation of Positive End-Expiratory Pressure (SpO2∗10/FiO2∗PEEP) for Classification and Prognostication of Patients wit... by Pratibha Todur, Anitha Nileshwar, Souvik Chaudhuri, Nitin Gupta, Srikant Natarajan, Shwethapriya Rao

“…The secondary objective was to determine the cut-off value of S/FP∗10 ratio to predict severe ARDS and survival. Methods. Patients aged 18–80 years on invasive mechanical ventilation (MV) diagnosed with ARDS as defined by the Berlin definition were included. …”
Get full text

Microwave Ablation of T1a and T1b Renal Masses: A Retrospective Study by Assim Saad Eddin, Karan Rao, Bradford Oliva, Ajmain Chowdhury, Shetty Zubin, Chad Tracy, Brian J. Smith, Sandeep T. Laroia

“…Oncologic outcomes were assessed using evidence of local tumor recurrence on contrast-enhanced cross-sectional imaging, local recurrence-free probability at 1 and 2 years, and overall survival (OS) using the Kaplan–Meier analysis.Forty-nine patients (57% males and 43% females) with a median age of 72 years (range, 38–84 years) underwent 53 MWA procedures. …”
Get full text

The Explo’Santé mixed methods protocol: an interventional research school health promotion project in France by Matteo Olivo, Adeline Darlington-Bernard, Corélie Salque, Laurie Fraticelli, Emmanuel Ricard, Florence Carrouel, Emily Darlington

“…This 3-year, complex programme targets primary school pupils aged 8 to 10. It incorporates health education sessions, to develop pupils’ LS and health literacy (HL), and to promote healthy environments. …”
Get full text

Post-COVID-19 laryngo-tracheal sequelae: a comprehensive study at a tertiary care centre by Karthik P., Rupa Mehta, Ranganath T. G., Ajoy K. Behra, Atul Jindal, Himanshi Grover

“…Results The study population included 348 participants, with an age distribution ranging from 21 to over 60 years. …”
Get full text

Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments by Ning Ning, Sunandana Chandra, Andriy Moshyk, Divya Patel, Isabella C Glitza Oliva, Jennell Palaia, Leon A Sakkal, Natalia Han, Shardul Odak, Jordana K Schmier

“…Patients receiving nivolumab plus ipilimumab, compared with patients receiving anti-PD-1 monotherapy or BRAF/MEK inhibitors, had favourable baseline prognostic factors, such as younger age, fewer or smaller brain metastases, better Eastern Cooperative Oncology Group performance status and less frequently elevated lactate dehydrogenase. …”
Get full text

Digital health data security practices among health professionals in low-resource settings: cross-sectional study in Amhara Region, Ethiopia by Ayenew Sisay Gebeyew, Wondwossen Zemene, Binyam Chaklu Tilahun, Nebyu Demeke Mengestie, Berhanu Fikade Endehabtu, Zegeye Regasa Wordofa, Mitiku Kassaw Takillo, Gedefaw Belete Ashagrie, Melaku Molla Sisay

“…Health professionals 41–45-year age group (AOR = 0.107), master’s degree (AOR = 2.45), postmaster’s degree (AOR = 3.87), time to visit the internet for more than two hours (AOR = 2.46), basic computer training (AOR = 2.77), training in digital data security (AOR = 2.14), and knowledge (AOR = 1.76) were associated with the practice of digital health data security. …”
Get full text

Analisis Faktor-Faktor Penentu Kepuasan Pengguna Layanan Paylater Dengan Pendekatan Regresi Linier by Kastaman, Siska Komala Sari, Tora Fahrudin, Heru Nugroho

“…The research method used is qualitative by means of a survey of 280 students with an average age group of 15-20 years, while the factors studied after conducting a literature study to find the strength of the relationship between the five independent variables: study program, gender, monthly income, monthly expenses, and awareness of paylater to the dependent variable, namely customer satisfaction with paylater services, were analysed using multiple linear regression. …”
Get full text

Aetiology and Outcomes of Thrombocytopenia in Pregnancy: A Cross-Sectional Study in a University Hospital, India by Sudha V. Hooli, Neelima Shah, Prashant Shah, Shrradha Suresh, Bali Sukeshani Sunil

“…Results: Overall, 64.7% of patients were in the 18–25 years age group and 49.6% of patients were primigravida. …”
Get full text

Evaluating the Efficacy of a Serious Game to Deliver Health Education About Invasive Meningococcal Disease: Clustered Randomized Controlled Equivalence Trial by Lauren Bloomfield, Julie Boston, Martin Masek, Lesley Andrew, Donna Barwood, Amanda Devine

“…ObjectiveThis study aims to develop a serious game that can replace a face-to-face educator in a classroom setting to educate adolescents aged 12 years to 15 years. This study evaluates the efficacy of the Meningococcal Immunisation Awareness, Prevention and Protection app (MIApp), a serious game designed to replicate the information provided in a 30-minute face-to-face presentation provided by a trained educator. …”
Get full text

La transformation de l’ancien centre de détention secrète de Derb Moulay Cherif en musée des « années de plomb » (Casablanca, Maroc) by Anissa Habane

“…Furthermore, as the mobilization of former political prisoners in the 2000s fades within ages. Thus, in the lack of political willingness to follow through on the IER’s recommendation to transform the site into a project for the preservation of memory, all those who have been in contact with the CDS-DMC from near or far refer to "blocked memory" (mémoire empêchée - Ricoeur, 2000, p. 83), preventing the work and duty of remembrance from being fully carried out.…”
Get full text

Cardio-renal effect of dapagliflozin and dapagliflozin- saxagliptin combination on CD34 + ve hematopoietic stem cells (HSCs) and podocyte specific markers in type 2 diabetes (T2DM)... by Seshagiri Rao Nandula, Arad Jain, Sabyasachi Sen

“…Methods This is a pilot study evaluating low dose Dapagliflozin 10 mg or low dose Dapa + low dose Saxagliptin combination. 15 subjects were enrolled in 16 weeks, double-blind, three-arm, randomized placebo matched trial, with 10mg Dapa + Saxa placebo (n = 4), 10 mg Dapa + 5 mg Saxa (n = 5) Combo, And Dapa placebo + Saxa placebo (n = 6), Placebo groups. T2DM subjects (age 30–70 yrs) with HbA1c of 7–10%, were included. …”
Get full text

Assessment of Asthma Control and Quality of Life among Asthmatic Patients Attending Armed Forces Referral and Teaching Hospital, Addis Ababa, Ethiopia by Tesfalidet Gebremeskel Zeru, Ephrem Engidawork, Alemseged Beyene Berha

“…Uncontrolled asthma was associated with middle-aged adults (adjusted odds ratio AOR=6.31; 95% CI: 2.06, 19.3; P=0.001), male gender (AOR=0.38; 95% CI: 0.15, 0.98; P=0.044), married (AOR=0.24; 95% CI: 0.08, 0.78; P=0.017), comorbidities (AOR=0.23; 95% CI: 0.09, 0.61; P=0.003), and oral SABA use (AOR=0.22; 95% CI: 0.09, 0.59; P=0.003). …”
Get full text

Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model by Cassandra M. Flynn, Tamunotonye Omoluabi, Alyssa M. Janes, Emma J. Rodgers, Sarah E. Torraville, Brenda L. Negandhi, Timothy E. Nobel, Shyamchand Mayengbam, Qi Yuan

“…TH-CRE rats (N = 47; 24 females and 23 males) received either AAV carrying pseudophosphorylated human tau (htauE14) or a control virus at 3 months of age. Probiotic or control diets were administered at 9–12 months, with blood and fecal samples collected for ELISA and 16S rRNA gene sequencing. …”
Get full text

TIGIT inhibitor M6223 as monotherapy or in combination with bintrafusp alfa in patients with advanced solid tumors: a first-in-human, phase 1, dose-escalation trial by Wei Gao, Ping Hu, Aung Naing, Meredith McKean, Anthony Tolcher, Lillian L Siu, Keyvan Tadjalli-Mehr, Anja Victor, Emilia Richter, Marco A F Nogueira Filho, Thomas Kitzing, Stephan Gleicher, Daniel Holland

“…Bintrafusp alfa (BA) is a bifunctional fusion protein that simultaneously blocks nonredundant immunosuppressive TGF-β and PD-(L)1 pathways.Methods This first-in-human, dose-escalation study in patients with advanced solid tumors (N=58; aged ≥18 years, ECOG PS≤1) evaluated M6223 alone (Part 1A, n=40; M6223 10–2400 mg every 2 weeks, n=32; M6223 2400 mg every 3 weeks, n=8) or with BA (Part 1B, n=18; M6223 300–1600 mg with BA 1200 mg; both every 2 weeks, intravenous). …”
Get full text

Assessment of Birth Preparedness and Complication Readiness among Pregnant Women: A Cross-sectional Study by T Elamathi, K Ananthi, Rimi Singh

“…The Student’s t-test was used for data comparison regarding the onset and duration of sensory and motor blockade, time of two-segment regression, time for rescue analgesia, haemodynamic stability and sedative effects between the study groups. Results: The mean age for Group-R was 45.00±7.1 years and Group-L 51.95±8.03 years. onset of sensory blockade at the T10 level and the onset of motor blockade in Group-R were slower than in Group-L (p-value <0.05). …”
Get full text