Impacts of drought on respiratory mortality in the upper midwest United States: a population subgroup assessment by Yeongjin Gwon, Yuanyuan Ji, Jesse D Berman, Azar M Abadi, Ronald D Leeper, Jared Rennie, Jesse E Bell

“…Stratification analyses were conducted by age group, gender, race, urbanicity, and state within the region. …”
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Effects of Mixing Tree Species on Soil Enzyme Activity and Carbon-Use Efficiency in Eroded Masson Pine Forest by WANG Man, JIANG Yongmeng, ZHANG Shiliang, ZHANG Jinxiu, ZHENG Linmin, ZENG Zhiwei, LYU Maokui, XIE Jinsheng

“…[Results] (1) With the increase of restoration years, soil acid phosphatase (AP) and β-glucosidase (βG) activities were significantly reduced, while C∶NEEA (βG∶NAG), vector length (VL) and vector angle (VA) of the mixed forest were lower than that of pure forest, while C∶PEEA (βG∶AP) and N∶PEEA (NAG∶AP) showed the opposite trend, indicating that long-term mixing is beneficial to alleviate the carbon limitation and phosphorus limitation of microorganisms. (2) Mixing was beneficial to improve CUE and significantly increased with the increase of forest age. Specifically, compared with that of Y39-CF and Y19-MF, CUE of Y39-MF significantly increased by 200.00% and 136.84%, respectively. (3) By analyzing the characteristics of soil enzyme activity and the relationship between CUE and environmental factors, it was found that soil carbon, nitrogen and phosphorus availability was an important influencing factor, mainly affecting AP activity, C∶PEEA, N∶PEEA, VL, VA and CUE, while the stoichiometric ratio of soil nutrients mainly affected βG activity and C∶NEEA. (4) The results of redundancy analysis (RDA) showed that the ratio of fungi and bacteria mainly affected the characteristics of soil enzyme activity and CUE in the mixed forest, while the main influencing factors in pure forest were actinomyces and Gram-negative bacteria. …”
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Early COVID-19 and protection from Omicron in a highly vaccinated population in Ontario, Canada: a matched prospective cohort study by Altynay Shigayeva, Christopher Kandel, Lubna Farooqi, Zoe Zhong, Anne-Claude Gingras, Brenda L. Coleman, Lois Gilbert, Wayne L. Gold, Maria Major, Tony Mazzulli, Samira Mubareka, Jelena Vojicic, Jingyan Yang, Pingping Zhang, Catherine Martin, Moe H. Kyaw, John M. McLaughlin, Allison McGeer

“…EI and BA.1/2 infection combined reduced later Omicron infection (HR 0.07 (0.03–0.21) compared to no prior infection. Older age, non-White ethnicity, no children in household, and lower neighbourhood income were associated with reduced risk of infection. …”
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The Potential Role of sPD-L1 as a Predictive Biomarker in EGFR-Positive Non-Small-Cell Lung Cancer by Vesna Ćeriman Krstić, Dragana Jovanović, Natalija Samardžić, Milija Gajić, Jelena Kotur Stevuljević, Aleksandra Klisic, Ivan Soldatović, Damir Radončić, Marina Roksandić Milenković, Biljana Šeha, Nikola Čolić, Katarina Lukić, Milan Savić

“…We analyzed sPD-L1 concentrations in 30 healthy middle-aged subjects, as a control population, to determine the reference range. …”
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An Analysis of the Effectiveness and Safety of Upadacitinib in the Treatment of Inflammatory Bowel Disease: A Multicenter Real-World Study by Hongzhen Wu, Tingting Xie, Qiao Yu, Tao Su, Min Zhang, Luying Wu, Xiaoling Wang, Xiang Peng, Min Zhi, Jiayin Yao

“…The study included adult patients aged 18 years or older, diagnosed with UC or CD, who received at least 8 weeks of upadacitinib therapy. …”
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The Protocol for the Multi-Ethnic, multi-centre raNdomised controlled trial of a low-energy Diet for improving functional status in heart failure with Preserved ejection fraction (... by Noelle Robertson, Melanie J Davies, Thomas Yates, Gerry P McCann, Gaurav Singh Gulsin, Emer M Brady, Joanne V Wormleighton, Eylem Levelt, Oliver Rider, Jiliu Pan, Christopher Miller, Iain Squire, Mehak Asad, Fardad Soltani, Michelle Hadjiconstantinou, Rachel L Brown, Joanna M Bilak

“…This pragmatic randomised trial aims to evaluate the efficacy of MRP-directed weight loss on exercise intolerance, symptoms, quality of life and cardiovascular remodelling in a multiethnic cohort with obesity and HFpEF.Methods and analysis Prospective multicentre, open-label, blinded endpoint randomised controlled trial comparing low-energy MRP with guideline-driven care plus health coaching. Participants (n=110, age ≥18 years) with HFpEF and clinical stability for at least 3 months will be randomised to receive either MRP (810 kcal/day) or guideline-driven care for 12 weeks. …”
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Cost-effectiveness analysis of three surgical approaches for parathyroidectomy in secondary hyperparathyroidism patients by Qila Sa, Qila Sa, Yinghui Zhou, Guangming Cheng, Boyuan Nan, Yingnan Feng, Yingnan Feng, Ningyuan Zhang, Ningyuan Zhang, Wantao Xie, Wantao Xie, Wei Zhang

“…Aim of this study is to compare medical costs and final outcomes associated with the three surgical approaches for the entire treatment duration, aiming to identify the most cost-effective surgical method.MethodsBased on previous research data from domestic and international studies, as well as data from on-site surveys, TreeAge Pro 2022 software was used to construct a Markov model for the surgical treatment of SHPT patients. …”
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Worldwide patterns and trends in ovarian cancer incidence by histological subtype: a population-based analysis from 1988 to 2017Research in context by Yi-Fan Wei, Li Ning, Yi-Lin Xu, Jing Ma, Dong-Run Li, Zan-Fei Feng, Fang-Hua Liu, Yi-Zi Li, He-Li Xu, Peng Li, Yong-Pei Yu, Dong-Hui Huang, Xiao-Ying Li, Song Gao, Chun-Qing Lin, Ting-Ting Gong, Qi-Jun Wu, Jing-He Lang

“…Annual percent changes were computed to describe trends in age-standardized rates (ASRs) of OC and its subtypes. …”
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Efficacy of Early Endoscopic Ultrasound-Guided Transluminal Drainage for Postoperative Pancreatic Fistula by Nao Fujimori, Takashi Osoegawa, Akira Aso, Soichi Itaba, Yosuke Minoda, Masatoshi Murakami, Kazuhide Matsumoto, Katsuhito Teramatsu, Yu Takamatsu, Takehiro Takaoka, Takamasa Oono, Eikichi Ihara, Tomoharu Yoshizumi, Takao Ohtsuka, Masafumi Nakamura, Yoshihiro Ogawa

“…Thirty patients (median age, 64.5 years) were enrolled. The most common initial operation was distal pancreatectomy with splenectomy (60.0%). …”
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Mid-term outcome and quality of life after Bentall procedure: single-center experience by I. O. Stetsyuk, L. R. Stetsiuk, B. M. Todurov, I. Yu. Mokryk, V. I. Zaviiskyi, I. P. Nechai, V. B. Demyanchuk, O. V. Zelenchuk

“…The research included 55 patients who underwent planned surgical treatment at the Heart Institute of Ministry of Health of Ukraine from 2015 to 2023. The mean age of the 55 patients (53 (96.36 %) males), who underwent the Bentall procedure (composite graft replacement of the aortic root), was 52.36 ± 1.56 years. …”
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Short-Term Effect of Air Pollution on Daily Hospital Visits for Anxiety Disorders in Southern China with Low Pollution Concentrations by Xinyuan Zhong, Tingting Guo, Jianghui Zhang, Qiong Wang, Rong Yin, Kunpeng Wu, Qing Zou, Meng Zheng, Brian J. Hall, Andre M. N. Renzaho, Kangning Huang, Wen Chen

“…The effects of NO₂ and CO remained robust across subgroup analyses and sensitivity analyses. Females and middle-aged individuals showed stronger associations than other subgroups. …”
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Immunomodulatory and anti-inflammatory potential of botanicals bioactive product (PHYTO AX'CELL™) for an improvement of the well-being of laying hens at the peak of production by Alessandro Guerrini, Roberta Salaroli, Augusta Zannoni, Giancarlo Avallone, Francesca Leone, Valentina Serra, Giulia Quaglia, Francesca del Zozzo, Thibaut Chabrillat, Claire Carlu, Caterina Lupini, Doriana Eurosia Angela Tedesco

“…In this study, 764 Lohmann LSL-White hens on the first day (d) of the 26th wk of age (T0), were randomly assigned to 2 replicated experimental groups, control and treated (n=382 each). …”
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Risk factors for the delayed discharge from anesthesia intensive care unit: a single-center retrospective study by Yue Qian, Jing Hao, Wei Zhu, Yan Yang, Zhuan-yun Zhang, Lu-yang Zhou, Xiao-ping Gu, Zheng-liang Ma, Yu-e Sun

“…It is influenced by various risk factors, including age, ASA physical status classification, BMI, preoperative complications, type of surgery and intraoperative blood loss. …”
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Associations of maternal PM2.5 exposure with preterm birth and miscarriage in women undergoing in vitro fertilization: a retrospective cohort study by Miaoxin Chen, Qiaoyu Chen, Gengze Liao, Chunyan Sun, Cong Liu, Xia Meng, Wentao Li, Andong Qiu, Orhan Bukulmez, Haidong Kan, Feng Wang, Lap Ah Tse, Xiaoming Teng

“…The objective of this study was to investigate the potential associations between ambient PM2.5 exposure during different periods and negative pregnancy outcomes, such as miscarriage and preterm birth, in patients who underwent assisted reproductive technology (ART).MethodsThis retrospective cohort study examined the outcomes of 2,839 infertile women aged ≤ 45 years who underwent their first fresh or frozen-thawed embryo transfer at the Shanghai First Maternity and Infant Hospital between April 2016 and December 2019. …”
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Ocular and Mucocutaneous Sequelae among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo by Bayaki Saka, Abla Séfako Akakpo, Julienne Noude Teclessou, Garba Mahamadou, Abas Mouhari-Toure, Kossi Dzidzinyo, Adam Nouhou Diori, Nidain Maneh, Sabin Prince-Agbodjan, Koussake Kombaté, Komi Balo, Kissem Tchangai-Walla, Palokinam Pitché

“…There were 113 women and 64 men, with an average age of 31.7±13.0 years (range: 5 to 80 years). The most used drugs were antibacterial sulfonamides (35.6%) and nevirapine (24.3%). …”
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Azithromycin to prevent acute lower respiratory infections among Australian and New Zealand First Nations and Timorese children (PETAL trial): study protocol for a multicentre, int... by Anne B Chang, Keith Grimwood, Yuejen Zhao, Gabrielle B McCallum, Catherine A Byrnes, Heidi Smith-Vaughan, Peter S Morris, Christine Connors, Adrian Trenholme, Shirley Lawrence, Joshua Francis, Kobi L Schutz, Mark D Chatfield, Nevio Sarmento, Robyn L. Marsh, Emily R Bowden, Nicholas Fancourt, Adriano Vieira, Kim M Hare, Dennis Bonney, Felicity Marwick, Bronwyn Karvonen, Carolyn Maclennan, Milena Santos Lay, Endang Soares da Silva

“…Our primary hypothesis is that children receiving long-term azithromycin will have fewer medically attended ALRIs over the intervention period than those receiving placebo.Methods and analysis We will recruit 160 Australian and New Zealand First Nations and Timorese children aged <2 years to a parallel, superiority RCT across four hospitals from three countries (Australia, New Zealand and Timor-Leste). …”
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Seroprevalence of Human Herpesvirus Infections in Newly Diagnosed HIV-Infected Key Populations in Dar es Salaam, Tanzania by Doreen Kamori, Agricola Joachim, Mucho Mizinduko, Godfrey Barabona, Macdonald Mahiti, Upendo Kibwana, Mtebe Majigo, Salim Masoud, Ambele M. Mwandigha, Takamasa Ueno, Elia Mmbaga, Eligius Lyamuya

“…We also observed that multiple coinfections with CMV-HSV-2 (p=0.042) and CMV-HSV-1-HSV-2 (p=0.006) were significantly associated with key population aged above 40 years. Conclusion. The IgG seroprevalence of CMV, HSV-1, and HSV-2 was high among HIV-positive key populations. …”
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sST2 as a New Biomarker of Chronic Kidney Disease-Induced Cardiac Remodeling: Impact on Risk Prediction by Maëlle Plawecki, Marion Morena, Nils Kuster, Leila Chenine, Hélène Leray-Moragues, Bernard Jover, Pierre Fesler, Manuela Lotierzo, Anne-Marie Dupuy, Kada Klouche, Jean-Paul Cristol

“…No patient had reduced ejection fraction. 112 patients had left ventricular hypertrophy, and 184 presented cardiac dysfunction, with structural, functional abnormalities or both. sST2 was independent of age and eGFR (ρ=0.05, p=0.44, and ρ=−0.07, p=0.3, respectively). …”
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Comparative Study on the Efficacy and Safety of Tumor Resection in Vitrectomy for Retinal Vasoproliferative Tumors by Bin Zheng, Yan Chen, Lifeng Chen, Huan Chen, Jingwei Zheng, Feng Chen, Zongming Song, Lin Fu, Xuting Hu, Jiandong Pan, Hengli Lian, Lijun Shen, Qiuming Li

“…Female (69%) were more common. The mean age was 50 (49.72 ± 12.92) years. Fifteen patients got unilateral onset and only one patient suffered bilaterally. …”
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Development and validation of a multidimensional, culturally and socially inclusive Child Resilience Questionnaire (parent/caregiver report) to measure factors that support resilie... by Deirdre Gartland, Elisha Riggs, Rebecca Giallo, Stephanie Janne Brown, Karen Glover, Kelsey Hegarty, Amanda Mitchell, Jane Yelland, Josef Szwarc, Sue Casey, Donna Weetra, Mardi Stowe, Sharon Mongta, Helen Herman, Selena White, Tanya Koolmatrie, Georgie Paxton

“…The parent/caregiver report (CRQ-P/C) is the focus of this paper.Setting Australia.Participants Culturally and socially diverse parents/caregivers of children aged 5–12 years completed the CRQ-P/C in the pilot (n=489) and validation study (n=1114). …”
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