Plasma circulating cell–free DNA integrity and relative telomere length as diagnostic biomarkers for Parkinson’s disease and multiple system atrophy: a cross-sectional study by Chao Ying, Chao Han, Yuan Li, Mingkai Zhang, Shuying Xiao, Lifang Zhao, Hui Zhang, Qian Yu, Jing An, Wei Mao, Yanning Cai

“…The diagnostic potential of the cell-free DNA parameters was evaluated using receiver operating characteristic (ROC) analysis, and their association with disease prevalence was examined through logistic regression models, adjusting for confounders such as age, sex, body mass index, and education level. …”
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Management and outcomes of thoracic sarcomas - a collaboration between Orthopaedic Oncology and cardiothoracic surgery: seven-year clinical data from a tertiary referral centre by Zaid Ahmed Shamsi, Vlad Paraoan, Chang Kim, Sarah Raihanah Saifuddin, Thomas D A Cosker, Duncan Whitwell, Christopher L M H Gibbons, Dionisios Stavroulias, Francesco DiChiara

“…Variability in outcomes and overall survival likely stems from factors such as histological diversity, predominance of high-grade sarcomas, and wide age range at diagnosis. Ongoing prospective database update and collaborative efforts across centres would further clarify prognoses and recommendations for specific tumours, based on observational data.…”
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Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur... by Lihua Huang, Liuliu He, Qingfeng Zeng, Jinjing Huang, Xiaoyan Luo, Qiuming Zhong

“…Hazard ratios (HR) and 95% confidence intervals (CIs) for all-cause and CVD mortality were calculated using weighted Cox proportional hazards and restricted cubic spline models.ResultsAmong the 1,931 participants (mean [SE] age, 73.2 [0.2] years; 61.9% female), over a median follow-up period of 7.6 years, a total of 1,003 deaths were observed, including 412 from CVD. …”
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Association between Air Pollution and Risk of Hospital Admission for Pediatric Pneumonia in a Tropical City, Kaohsiung, Taiwan by Peng-Huei Liu, Kuo-Chen Huang, Yu-Lun Tseng, I-Min Chiu, Hsiu-Yung Pan, Fu-Jen Cheng

“…The medical records of non-traumatic patients under 17 years of age who had visited the ED between 2008 to 2013, with a principal diagnosis of pneumonia were extracted. …”
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Lifestyle risk factors for overweight and obesity among rural Indian adults: a community-based prospective cohort study by Rajesh Kumar Rai, Sabri Bromage, Jan-Walter De Neve, Anamitra Barik

“…To address this evidence gap, this study used cohort data (baseline: 2018–19, follow-up: 2022–23) from the Birbhum Population Project (West Bengal, India) to analyse lifestyle risk factors and their association with incidence and remission of overweight/obesity among adults aged ≥18 years (sample: 8,974). Modified Poisson regression model was employed to attain the study objective. …”
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Owners’ perceptions of dog treat management in Western Romania by Sorana Daina, Anamaria Blaga-Petrean, Silvana Popescu, Ioana Delia Pop, Daniel Mierlita, Adrian Macri

“…The wide range and availability of these products often pair with the fondness of owners for their companions, leading to overfeeding them with rewards.MethodsThis study explored owner treat provision behaviors among 890 voluntarily participating dog owners in Western Romania through an online survey conducted between June and November 2023.ResultsThe majority of respondents were women (72%) and younger adults aged 18–24 (39%). Emotional attachment was the primary motivation for providing treats (52%), followed by perceived health benefits (35%) and training purposes (25%). …”
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Time without PSA recurrence after radical prostatectomy as a predictor of future biochemical recurrence, metastatic disease and prostate cancer death: a prospective Scandinavian co... by Mats Steinholtz Ahlberg, Hans-Olov Adami, Hans Garmo, Lars Holmberg, Anna Bill-Axelson, Ove Andren, Gunnar Steineck, Jan-Erik Johansson

“…Median preoperative PSA was 9.8 ng/mL and median age was 65 years. For patients without biochemical recurrence 5 years after radical prostatectomy the 20-year probability of biochemical recurrence was 25% among men with Gleason score ≤3+4=7 and 57% among men with Gleason score ≥4+3=7; the probabilities for metastases were 0.8% and 17%; and for prostate cancer death 0.8% and 12%, respectively. …”
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Modern options of endoscopic retrograde stenting of bile ducts in treatment of obstructive jaundice at malignant pancreatobiliary tumors by S. A. Budzinsky, S. G. Shapovalyants, Ye. D. Fedorov, A. G. Mylnikov, D. V. Bakhtiozina

“…Endoscopic stenting of biliary tract have been carried out in 523 cases, of them 418 (79,9%) procedures were carried out in 287 patients with jaundice of neoplastic origin (148 women, 139 men). Patients were in the age of 32 to 94 years (mean 68,2±9,3 year). With the help of the comprehensive diagnostic program providing ultrasound investigation, computer tomography, endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography, it was possible to determine in 207 (72,1%) cases the distal block of biliary tract due to tumors of MDP, terminal CBD portion, distal part of common bile duct and pancreatic head, and the proximal block in 80 (27,9%) cases at lesions of gallbladder, hepatico-choledochal duct, lobar hepatic ducts or compression of proximal biliary tree by lymph nodes of hepatoduodenal ligament.Results. …”
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Randomised controlled trial of topical kanuka honey for the treatment of rosacea by James Fingleton, Mark Weatherall, Richard Beasley, Irene Braithwaite, Janwillem Kocks, Mark Holliday, Andrew Corin, Colin Helm, Davitt Sheahan, Barney Montgomery, Judith Riley, Anna Hunt, Christopher Tofield

“…Objective To investigate the efficacy of topical 90% medical-grade kanuka honey and 10% glycerine (Honevo) as a treatment for rosacea.Design Randomised controlled trial with blinded assessment of primary outcome variable.Setting Outpatient primary healthcare population from 5 New Zealand sites.Participants 138 adults aged ≥16, with a diagnosis of rosacea, and a baseline blinded Investigator Global Assessment of Rosacea Severity Score (IGA-RSS) of ≥2. 69 participants were randomised to each treatment arm. 1 participant was excluded from the Honevo group, and 7 and 15 participants withdrew from the Honevo and control groups, respectively.Interventions Participants were randomly allocated 1:1 to Honevo or control cream (Cetomacrogol), applied twice daily for 8 weeks.Main outcome measures The primary outcome measure was the proportion of participants who had a ≥2 improvement in the 7-point IGA-RSS at week 8 compared to baseline. …”
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Association of Cardiovascular Disease Risk Factors With Estimated Dietary Salt Consumption in Bangladeshi Adults: A Nationally Representative Cross‐Sectional Study by Lingkan Barua, Tahmina Akhter, Rijwan Bhuiyan, Halima Akter Sathi, Palash Chandra Banik, Mithila Faruque, Muhammad Aziz Rahman, Sheikh Mohammed Shariful Islam

“…It included a non‐institutionalized adults’ population of 6189 men and women aged 18–69 years. Their daily salt consumption was estimated using the spot urine sodium concentration following the Tanaka equation and reported according to the standard nomenclature proposed by the World Hypertension League and partner organizations involved in dietary salt reduction. …”
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Determinants maintaining healthcare personnel’s motivation during COVID-19 pandemic in Uganda by Makiko Komasawa, Myo Nyein Aung, Christopher Nsereko, Kiyoko Saito, Robert Ssekitoleko, Mitsuo Isono, Motoyuki Yuasa

“…Factors positively associated with remaining motivated were age (≤ 30 versus > 30 years; adjusted odds ratio [AOR]: 10.34, 95% CI; 1.92–55.74), profession (co-medical/non-medical staff versus medical doctors/medical officers; AOR: 11.66, 95% CI: 1.03–132.22), receiving mentoring/tutoring (AOR: 18.87, 95% CI: 2.55–139.72), and information from supervisors/management (AOR: 12.5, 95% CI: 2.60–60.42). …”
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MOBILITAS SPASIAL LANSIA DI RUANG LUAR PERMUKIMAN PADAT KOTA by Diananta Pramitasari, Mutiara Anggi

“…These areas accommodate various groups of people, including the elderlies, choosing to stay permanently in the neighborhood for relishing old age life. Physical limitations faced by the elderlies do not reduce the need to keep going out, including walking around the settlement. …”
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Bony ankylosis adversely affects postoperative hip function in patients with ankylosing spondylitis undergoing total hip arthroplasty: a retrospective cohort study of 319 consecuti... by Liangliang Li, Jun Fu, Chi Xu, Ming Ni, Wei Chai, Libo Hao, Yonggang Zhou, Jiying Chen

“…Methods We identified 544 primary THAs performed in 319 consecutive patients with AS (median age, 33 years) from 2012 to 2017. Survivorship of the implants, complications, and patient satisfaction were investigated. …”
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Multinational comparison of new antidepressant use in older adults: a cohort study by Robyn Tamblyn, David Westfall Bates, David L Buckeridge, Will Dixon, Alan J Forster, Nadyne Girard, Jennifer Haas, Bettina Habib, Siyana Kurteva, Jack Li, Therese Sheppard

“…Objectives We used an international pharmacosurveillance network to estimate the rate and characteristics of antidepressant use in older adults in countries with more conservative (UK) and liberal depression guidelines (Canada, USA).Setting Electronic health records and population-based administrative data from six jurisdictions in four countries (UK, Taiwan, USA and Canada).Participants A historical cohort of older adults (≥65 years) who had a new episode of antidepressant use between 2009 and 2014.Outcome measures The age and sex-standardised cumulative incidence of new episodes of antidepressant use in older adults was measured. …”
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Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery by Mengli Zhang, Ziyi Zhang, Ningning Zhu, Lulu Wang, Hui Huang, Yike Wang, Fang Xue

“…The results of the meta-analysis indicated that statistically significant risk factors included age >65 years [odds ratios (OR) (95% CI ) = 3.47 (2.61–4.32)], female gender [OR (95%) = 1.54 (1.34–1.76)], combined heart valve and coronary artery bypass surgery [OR (95%) = 1.82 (1.23–2.70)], ejection fraction <40% [OR (95%) = 1.38 (1.17–1.63)], history of heart surgery [OR (95%) = 1.30 (1.06–1.59)], myocardial infarction [OR (95%) = 1.17 (1.05–1.31)], hyperlipidemia [OR (95%) = 0.76 (0.67–0.86)], hypertension [OR (95%) = 1.12 (1.03–1.22)], anticoagulant medication [OR (95%) = 0.77 (0.65–0.90)], cardiopulmonary bypass time >2 hours [OR (95%) = 20.26 (17.03–23.48)] and history of cardiopulmonary bypass [OR (95%) = 1.24 (1.09–1.41)]. …”
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The association between 24-h movement behaviours and adiposity among Australian preschoolers: a compositional data analysis by Marga Decraene, Kar Hau Chong, Ty Stanford, Dorothea Dumuid, Penny Cross, Greet Cardon, Vera Verbestel, Marieke De Craemer, Anthony Okely

“…Their parents completed a questionnaire to assess their level of education and the child’s sleep duration, age and sex. CoDA was employed to investigate the association between 24-h movement behaviours and adiposity in R. …”
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Factors influencing the kinetics of MSU crystal depletion measured with dual-energy CT in patients with gout by Tristan Pascart, Victor Laurent, Charlotte Jauffret, Aurore Pacaud, Vincent Ducoulombier, Julie Legrand, Stéphane Verdun, Laurène Norberciak, Jean-François Budzik

“…Associations between percentage change from the baseline volume of MSU crystal deposits and explanatory variables were assessed using linear mixed models.Results Sixty-two patients (age 67.3±12.8 years; 53 (85%) males) cumulating 104 follow-up DECT scans were included. …”
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Inflammatory burden index as a prognostic marker in patients with advanced gastric cancer treated with neoadjuvant chemotherapy and immunotherapy by Jiao-Bao Huang, Zhi-Yong Zhou, Jun Lu, Ji-Yun Zhu, Bin Lai, Sheng-Xun Mao, Jia-Qing Cao

“…Finally, Inflammatory burden index(IBI) was grouped by X-tile software, and Kaplan-Meier method was used to compare the survival difference between groups.ResultsA total of 163 patients were enrolled in this study. The median age was 63 years(56-68). The median cycle of neoadjuvant therapy was 4(3-4). …”
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Changes in the histological structure of tissues and organs of pikeperch (Sander lucioperca Linnaeus, 1758) and perch (Perca fluviatilis Linnaeus, 1758) from the Zaporizhzhia Reser... by P. Korzhenevska, T. Sharamok, A. Doroshenko

“…The object of the study were age-3+ pikeperch and perch. The number of fishes used in the study was 20 specimens of each species. …”
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Yngre förskolebarns litteratursamtal by Hanna Thuresson

“…This article aims to contribute knowledge about how children aged 1–2 years interact in literary encounters when educators are not involved. …”
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