Self-perception of risk for HIV acquisition among people in prisons in Iran: A nationwide survey in 2017 by Zahra Abdolahinia, Seyed Aria Nejadghaderi, Soheil Mehmandoost, AliAkbar Haghdoost, Abedin Iranpour, Mohammad Karamouzian, Hamid Sharifi

“…Results Among 5,422 HIV-negative participants (94.0% men; mean age 35.7 years), 6.8% (95% CI: 6.1–7.5%) reported high self-perception of risk for HIV acquisition. …”
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Disproportionality analysis of upadacitinib-related adverse events in inflammatory bowel disease using the FDA adverse event reporting system by Shiyi Wang, Xiaojian Wang, Jing Ding, Xudong Zhang, Hongmei Zhu, Yihong Fan, Changbo Sun

“…Subgroup analysis indicated that the most prevalent AEs among the elderly included pulmonary embolism, cataract, and sepsis, whereas the 18–65 age group most frequently reported acne, abdominal pain, and nasopharyngitis. …”
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Associations of combined exposure to selected metal mixtures with thyroid hormones in children: a cross-sectional study in China by Yuhan Cao, Shiting Xiang, Yuwei Du, Meiling Chen, Rumeng Xue, Qi Li, Jun Qiu, Yanying Duan

“…However, evidence for combined exposure is inconclusive, especially for children.ObjectiveTo examine the individual and joint effects of blood metal elements on thyroid hormones in children.MethodsA total of 12,470 children aged 0–14 were collected from January 2018 to December 2021 in Hunan Children's Hospital. …”
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Correlation between immune signature and high‐density lipoprotein cholesterol level in stage II/III colorectal cancer by Yun Wang, Xiao‐qiang Sun, Hao‐cheng Lin, De‐shen Wang, Zhi‐qiang Wang, Qiong Shao, Feng‐hua Wang, Shu‐mei Yan, Jie‐ying Liang, Zhao‐lei Zeng, Huai‐qiang Ju, Rui‐hua Xu, Yu‐hong Li

“…Fifty‐five pairs of tumor tissues were selected according to the variation in HDL‐C levels (high or low) and the matched characterizes (ages, T stage, and N stage). Using immunohistochemistry, tumor tissues were stained with antibodies against CD3, CD8, CD163, iNOS, Forkhead box P3 (FOXP3), and CD33. …”
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Molecular evidence of the inhibitory potential of melatonin against sodium arsenite toxicity by Ramtin Farhadi, Marzieh Daniali, Maryam Baeeri, Reza Khorasani, Hamed Haghi-Aminjan, Mahdi Gholami, Mahban Rahimifard, Mona Navaei-Nigjeh, Mohammad Abdollahi

“…Methods: Forty-eight adult healthy male wistar rats aged 7–8 weeks were divided into eight for this research. …”
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The burden and outcomes of firearm injuries at two district-level emergency centres in Cape Town, South Africa: A descriptive analysis by L Bush, C Hendrikse, C Van Koningsbruggen, K Evans

“…Of the 776 patients with firearm injuries who were included, the median age was 27 years, and 91% were male. A total of 520 (67%) patients self-presented, and there were 18 (2.3%) deaths in the emergency centre and a further 23 (3%) as inpatients. …”
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Monozygotic twins with myocarditis and a novel likely pathogenic desmoplakin gene variant by Antheia Kissopoulou, Eva Fernlund, Christina Holmgren, Eira Isaksson, Jan‐Erik Karlsson, Henrik Green, Jon Jonasson, Rada Ellegård, Hanna Klang Årstrand, Anneli Svensson, Cecilia Gunnarsson

“…The aim of this case presentation is to shed light upon a possible link between myocarditis, a desmoplakin (DSP) gene variant, and ARVC by describing a case of male monozygotic twins who presented with symptoms and signs of myocarditis at 17 and 18 years of age, respectively. One of them also had a recurrent episode of myocarditis. …”
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Safety and feasibility of En‐bloc holmium laser enucleation for very large prostates (> 200 cc) with trainee involvement by Feres C. Maluf, Ansh Bhatia, Archan Khandekar, Diana M. Lopategui, Joao G. Porto, Ryan R. Chen, Jean C. Daher, Mohamadhusni Zarli, Robert Marcovich, Hemendra N. Shah

“…Results The analysis included 89 patients with a mean age of 73.12 ± 8.10 years. Preoperative prostate weight ranged from 200 to 401 cc with a median of 245 cc, and median PSA was 7.71 ng/ml. …”
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Early initiation of intravenous cyclophosphamide and one‐year outcome in super‐refractory cryptogenic‐new onset refractory status epilepticus by Yasufumi Yorichika, Shuichiro Neshige, Hideaki Sakahara, Narumi Ono, Megumi Nonaka, Yuichiro Tagane, Tomoaki Watanabe, Keisuke Tachiyama, Haruka Ishibashi, Masahiro Nakamori, Takeo Shishido, Shiro Aoki, Hiroki Ueno, Yu Yamazaki, Takahiro Iizuka, Hirofumi Maruyama

“…We compared functional outcomes at 3 months and 1 year after the onset between patients who received IVCPA within 20 days (early‐treated) and those who received it later (late‐treated). All patients (median age: 43 years) had a prodromal fever. Brain MRI revealed symmetrically increased FLAIR signals in the medial temporal lobes of all patients. …”
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Urban environment during pregnancy, cognitive abilities, motor function, and externalizing and internalizing symptoms at 2–5 years old in 3 Canadian birth cohorts by Anne-Claire Binter, Dany Doiron, Martine Shareck, Tona Pitt, Sheila W. McDonald, Padmaja Subbarao, Wiliam D. Fraser, Suzanne C. Tough, Jeffrey Brook, Mònica Guxens

“…Validated neuropsychological tests were used to assess non-verbal and verbal abilities, gross and fine motor function, externalizing and internalizing symptoms at child’s age 2 to 5 years. We assessed associations of each environmental exposure indicator with each of the 6 outcomes, using multivariate linear regression models. …”
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Gut microbiota and kidney function in autosomal dominant polycystic kidney disease participants in Cameroon: a cross-sectional study by Inès Obolo Nwaga, Victorine Bandolo Nzana, Rhoda Nsen Bughe, Isaac Dah, Cheboh Cho-Fon, Maimouna Mahamat, Emmanuelle Ndjong, Aristide Nono, Jean Claude Mballa, Fon Abongwa Acho, Vicky Ama Moor, Wilfred Fon Mbacham, François Folefack Kaze

“…Differences between ADPKD subgroups and controls were assessed using nonparametric tests. Results The mean age (SD) of the 44 participants was 40.65 (± 11.9) years. …”
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From across the globe – traumatic injuries are an international concern at the US-Mexico border wall by Allison E Berndtson, Jay Doucet, Todd W Costantini, Laura Haines, Sarah Lagan, Laura Adams, Jarrett Santorelli, Gabriella Waters

“…Patients’ nationality was then stratified by region of the world to understand geographic representation of border injury admissions.Results We identified 597 patients injured while crossing the US-Mexico border wall representing 38 different countries. The mean age of patients was 32.2±10.4 years and 446 (75%) were male. …”
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Data-driven insights into pre-slaughter mortality: Machine learning for predicting high dead on arrival in meat-type ducks by Chalita Jainonthee, Phutsadee Sanwisate, Panneepa Sivapirunthep, Chanporn Chaosap, Raktham Mektrirat, Sudarat Chadsuthi, Veerasak Punyapornwithaya

“…The objective of this study was twofold: first, to classify high DOA rates (≥ 0.15%) using several predictors, including season, period of the day, number of ducks per truckload, distance, duration of transportation, age, average body weight, lairage time, and temperature at the lairage area. …”
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Prevalence of Corneal Astigmatism in Patients before Cataract Surgery in Western China by Wei Ma, Chengguo Zuo, Weirong Chen, Shaoyang Zheng, Jiangang Xu, Ruowen Gong, Maierhaba Mijiti, Kaidiliya Alifu, Lin Ding, Mingkai Lin

“…This study comprised 12,236 eyes of 7065 patients with a mean age of 64.75 ± 9.66 years, and 52.77% of the patients were female. …”
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Association between sleep duration and hypertension in southwest China: a population-based cross-sectional study by Yu Guo, Liming Li, Zhengming Chen, Qiang Sun, Pei Pei, Xianping Wu, Ningmei Zhang, Xiaofang Chen, Guojin Luo, John S Ji, Xiaoyu Chang, Xiaofang Chen*

“…Participants were enrolled in 15 townships of Pengzhou city in Sichuan province during 2004–2008.Participants 55 687 participants aged 30–79 years were included. Sleep duration was assessed by a self-reported questionnaire.Main outcome measures Hypertension was defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg, or prior physician-diagnosed hypertension in hospitals at the township (community) level or above.Results The prevalence of hypertension was 25.17%. …”
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Behavior of SD-OCT Detectable Hyperreflective Foci in Diabetic Macular Edema Patients after Therapy with Anti-VEGF Agents and Dexamethasone Implants by Anne Rübsam, Laura Wernecke, Saskia Rau, Dominika Pohlmann, Bert Müller, Oliver Zeitz, Antonia M. Joussen

“…Diabetic macular edema (DME) is the most common cause of blindness in the working-age population. Spectral-domain optical coherence tomography (SD-OCT) allows detection and monitoring of the edema and a detailed analysis of the retinal structure. …”
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Intramedullary Fixation for Metacarpal Fractures: A Multi-Institutional Prospective Outcomes Study by Michael B. Gehring, MD, Brandon Wolfe, BA, Riley Kahan, BS, Stephanie D. Malliaris, MD, Kia M. Washington, MD, Matthew D. Folchert, MD, Kyros Ipaktchi, MD, Mark A. Greyson, MD, Alexander Lauder, MD, Matthew L. Iorio, MD

“…Results: One-hundred-one fractures were treated in 82 patients with an average age of 33 years and mean follow-up of 69 days. Most patients were male (70%), nonlaborers (72%), and nonsmokers (74%). …”
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Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOk... by Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham

“…Background MLC1501, consisting of four herbs, that is, Radix Astragali, Radix Angelicae sinensis, Rhizoma Chuanxiong, Radix Polygalae, has the same pharmacological properties as its precursors MLC601 and MLC901 which contain extracts of nine herbs and showed neuroprotective, anti-inflammatory and neurorestorative properties in non-clinical models, as well as clinical benefits in improving functional and neurological recovery after brain injuries.Aims To determine the efficacy of MLC1501 on motor recovery as measured by Fugl-Meyer motor Assessment (FMA) total score at 24 weeks in patients with ischaemic stroke (IS).Design A total of 300 patients aged >18 years, diagnosed with IS in the prior 2–10 days, with National Institute of Health Stroke Scale (NIHSS) total score of 8–18 and a combined score of ≥3 on NIHSS motor items 5A, 5B, 6A and/or 6B, will be randomised in a 1:1:1 ratio to receive oral placebo, MLC1501 low dose or MLC1501 high dose for 6 months. …”
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Electronic cigarette use and chest pain in US adults: Evidence from the PATH study by Leili Behrooz, Wubin Xie, Aboli Goghari, Rosemarie Robertson, Aruni Bhatnagar, Andrew Stokes, Naomi M. Hamburg

“…Presence of established cardiovascular disease was examined at wave 4, and participants aged >40 years were asked about chest pain during wave 5. …”
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Childhood body size, adulthood adiposity, underlying mechanisms, and risk of incident hypertension: a prospective cohort study of 180,527 participants by Shujing Ma, Xue Liu, Ruilang Lin, Ye Yao, Min Zhao, Yongfu Yu, Costan G. Magnussen, Bo Xi

“…Methods A total of 180,527 participants from the UK Biobank aged 37 to 73 years were included. Associations of childhood body size or adulthood adiposity status as well as child–adult weight status change with incident adulthood hypertension were estimated by multivariate Cox proportional regression models. …”
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