Clinical and imaging features of co-existent pulmonary tuberculosis and lung cancer: a population-based matching study in China by Fan Zhang, Fei Qi, Yi Han, Hongjie Yang, Yishuo Wang, Guirong Wang, Yujie Dong, Hongxia Li, Yuan Gao, Hongmei Zhang, Tongmei Zhang, Liang Li

“…Methods Patients diagnosed with active PTB-LC (APTB-LC), inactive PTB-LC (IAPTB), and LC alone without PTB between 2010 and 2022 at our institute were retrospectively collected and 1:1:1 matched based on gender, age, and time of admission. Symptoms and clinicopathological features were compared among the three groups of patients. …”
Get full text

Right ventricular–pulmonary artery coupling in cardiac resynchronization therapy: evolution and prognosis by Jan Stassen, Xavier Galloo, Kensuke Hirasawa, Surenjav Chimed, Nina Ajmone Marsan, Victoria Delgado, Pieter van derBijl, Jeroen J. Bax

“…A total of 807 patients (age 66 ± 11 years, 76% men) were analysed. During a median follow‐up of 97 (54–143) months, 483 (60%) patients died. …”
Get full text

Pediatric endoscopic retrograde pancreatography expertise in chronic pancreatitis: a single-center analysis by Hongxi Guo, Juan Luo, Hu Yang, Jun Yang, Hongqiang Bian, Xufei Duan, Xin Wang

“…However, data on endoscopic treatment of CP in children are still limited.MethodsDemographics, etiology, surgical indications, diagnosis, treatment details, associated complications, and follow-up information were retrospectively studied in consecutive patients (<18 years old) who underwent ERP for CP between January 2020 and October 2024.ResultsA total of 17 children (7 male, 10 female) with a mean age of 10.0 ± 2.7 years were included in the study. …”
Get full text

Ultrasound-Guided Percutaneous Balloon Aortic Valvuloplasty for Aortic Stenosis by Yedan Li, Kunjing Pang, Yao Liu, Muzi Li, Hao Wang

“…This case series included 30 patients (14 males; mean age, 61.5 ± 4.5 years) with moderate/severe aortic stenosis treated with ultrasound-guided PBAV at the Ultrasound Department, Fuwai Hospital, Beijing, China, between January 2016 and July 2019. …”
Get full text

Admission outcomes and their associated factors among children admitted to the paediatric emergency unit within 24 hours of Dilla University Referral Hospital, Ethiopia, 2023: a cr... by Binyam Tariku Seboka, Tomas Yeheyis, Yihenew Ayehu Dessie, Samuel Jigso Dube, Abel Desalegn Demeke, Mekdes Mekonnen Feleke, Abdo Hajo Jarso, Asresu Feleke Bati, Etaferaw Udo, Selam Tadele Markos, Chalachew Kassaw, Amdehiwot Aynalem Debebe, Ephrem Geja Gechere

“…A total of 885 complete charts of the children aged 29 days to 14 years were analysed. Structured checklist was used for data collection. …”
Get full text

An exploratory analysis of differences in serum protein expression by sex in patients with systemic sclerosis associated interstitial lung disease by Giuliana Cerro-Chiang, Matthew Ayres, Alejandro Rivas, Sarah J. Parker, Mitra Mastali, Peter Chen, Jennifer E. Van Eyk, Paul J. Wolters, Francesco Boin, Tanzira Zaman

“…Even though men are less likely to develop systemic sclerosis, they have a higher incidence of SSc-ILD than women, and they tend to develop it at a younger age with a higher mortality rate. Sex differences in protein expression in the blood of patients with SSc-ILD have not been reported to date. …”
Get full text

Temporal patterns of macrophage‐ and neutrophil‐related markers are associated with clinical outcome in heart failure patients by Dominika Klimczak‐Tomaniak, Elke Bouwens, Anne‐Sophie Schuurman, K. Martijn Akkerhuis, Alina Constantinescu, Jasper Brugts, B. Daan Westenbrink, Jan vanRamshorst, Tjeerd Germans, Leszek Pączek, Victor Umans, Eric Boersma, Isabella Kardys

“…Mean (±standard deviation) age was 67 ± 13 years; 189 (72%) were men; left ventricular ejection fraction (%) was 32 ± 11. …”
Get full text

Association of exposure to second-hand smoke during childhood with blood DNA methylation by Marta Cosin-Tomas, Thanh Hoang, Cancan Qi, Giulietta S. Monasso, Ryan Langdon, Simon Kebede Merid, Lucinda Calas, Paula de Prado-Bert, Rebecca Richmond, Vincent VW Jaddoe, Liesbeth Duijts, John Wright, Isabella Annesi-Maesano, Regina Grazuleviciene, Marianna Karachaliou, Gerard H. Koppelman, Erik Melén, Olena Gruzieva, Martine Vrijheid, Paul Yousefi, Janine F. Felix, Stephanie J. London, Mariona Bustamante

“…Methods: Six cohorts from the Pregnancy And Childhood Epigenetics (PACE) Consortium (total N = 2,695), with SHS data and child blood DNAm (aged 7–9 years) measured with the Illumina 450K array were included in the meta-analysis. …”
Get full text

Case report: Novel ACTN4 variant of uncertain significance in a pediatric case of steroid-resistant nephrotic syndrome requesting kidney transplantation by Ignacio Alarcón, Carolina Peralta, Francisco Cammarata-Scalisi, Maykol Araya Castillo, Francisco Cano, Francisco Cano, Angélica Rojo, María Luisa Ceballos, María Luisa Ceballos, Paola Krall, Paola Krall

“…Within a few weeks, proteinuria rapidly increased, and a kidney biopsy exhibited FSGS features. At the age of 12, he reached ESKD and initiated peritoneal dialysis, experiencing an episode of posterior reversible encephalopathy syndrome. …”
Get full text

Weight-based enoxaparin thromboprophylaxis in young trauma patients: analysis of the CLOTT-1 registry by Sarah Lombardo, Ram Nirula, Elliott R Haut, Scott Brakenridge, Brandon Bruns, Charles E Wade, M Margaret Knudson, Thomas Scalea, Todd W Costantini, Lisa Marie Knowlton, David Spain, Ernest E Moore, Michelle K McNutt, Matthew J Martin, Andrew J Kerwin, George C Velmahos, Bruce Crookes, Marta McCrum, Lucy Kornblith, Mark D Cipolle, Laszlo N Kiraly, David J Milia, Alicia Mohr, Frederick Rogers, Sherry Sixta, Jade Nunez

“…Further studies need to evaluate these findings across a wider age and comorbidity spectrum.Level of evidence Level IV, therapeutic/care management.…”
Get full text

Aetiology of chronic liver disease is a valuable factor for stratifying adverse outcomes of acute decompensation: prospective observational study by Jung Hee Kim, Sung-Eun Kim, Do Seon Song, Hee Yeon Kim, Eileen L. Yoon, Ji Won Park, Tae Hyung Kim, Young-Kul Jung, Ki Tae Suk, Hyung Joon Yim, Jung Hyun Kwon, Sung Won Lee, Seong Hee Kang, Moon Young Kim, Soung Won Jeong, Jae-Young Jang, Jeong Ju Yoo, Sang Gyune Kim, Young-Joo Jin, Gab Jin Cheon, Byung Seok Kim, Yeon Seok Seo, Hyoungsu Kim, Dong Hyun Sinn, Woo Jin Chung, Hwi Young Kim, Han Ah Lee, Seung Woo Nam, In Hee Kim, Ji Hoon Kim, Hee Bok Chae, Joo Hyun Sohn, Ju Yeon Cho, Yoon Jun Kim, Jin Mo Yang, Jung Gil Park, Won Kim, Hyun Chin Cho, Dong Joon Kim

“…In this study, we assess the clinical attributes and prognostic implications of AD with CLD/LC stratified by the aetiology.Results Among 1,501 patients, the mean age was 54.7 years old and 1,118 patients (74.5%) were men. …”
Get full text

Approaches for difficult-to-induce-seizures electroconvulsive therapy cases (DEC): a Japanese expert consensus by Yoshiteru Takekita, Taro Suwa, Kazuyuki Yasuda, Hirotsugu Kawashima, Wataru Omori, Naoki Kurimoto, Takashi Tsuboi, Takamasa Noda, Nobuatsu Aoki, Ken Wada, Ken Inada, Minoru Takebayash, Expert Consensus Development Working Group, Electroconvulsive Therapy Committee, Japanese Society of General Hospital Psychiatry

“…Abstract Background Seizure threshold increases with age and the frequency of electroconvulsive therapy (ECT). …”
Get full text

Triglyceride-glucose-body mass index and the incidence of cardiovascular diseases: a meta-analysis of cohort studies by Xiyun Rao, Ziyi Xin, Qingwen Yu, Lanlan Feng, Yongmin Shi, Ting Tang, Xuhan Tong, Siqi Hu, Yao You, Shenghui Zhang, Jiake Tang, Xingwei Zhang, Mingwei Wang, Ling Liu

“…The results indicated that Compared with the lowest TyG-BMI index category, the highest TyG-BMI index was related to a higher incidence of cardiovascular diseases (CVD) (HR = 1.62; 95% confidence interval (CI): 1.35–1.95; I2 = 94%),coronary artery disease (CAD) (HR = 1.69; 95% (CI): 1.23–2.31; I2 = 94%). stroke(HR = 1.57; 95% (CI): 1.11–2.23; I2 = 94%).In the dose–response analysis, there was a linear association of the TyG-BMI index with the risk of CVD (Pnonlinear = 0.223), CAD (Pnonlinear = 0.693), and stroke (Pnonlinear = 0.122)No significant effects were observed regarding participants’ gender, length of follow-up, sample size or mean age(P > 0.05). Conclusion Higher TyG-BMI may be independently associated with an increased risk of CVD in individuals without CVD at baseline. …”
Get full text

Identifying health risk determinants and molecular targets in patients with idiopathic pulmonary fibrosis via combined differential and weighted gene co-expression analysis by Abu Tayab Moin, Md. Asad Ullah, Jannatul Ferdous Nipa, Mohammad Sheikh Farider Rahman, Afsana Emran, Md. Minhazul Islam, Swapnil Das, Tawsif Al Arian, Mohammad Mahfuz Enam Elahi, Mukta Akter, Umme Sadea Rahman, Arnab Halder, Shoaib Saikat, Mohammad Jakir Hosen

“…IntroductionIdiopathic pulmonary fibrosis (IPF) is a rare but debilitating lung disease characterized by excessive fibrotic tissue accumulation, primarily affecting individuals over 50 years of age. Early diagnosis is challenging, and without intervention, the prognosis remains poor. …”
Get full text

Health-related Quality of Life and Exercise Capacity in Double Lung Transplant Recipients With Baseline Lung Allograft Dysfunction by Alisha Rullay, BSc, Karina Kaur, BSc, Jennifer Holman, PT, Laura C. van den Bosch, MD, Justin G. Weinkauf, MD, Jayan Nagendran, MD, PhD, Rhea A. Varughese, MD, Alim S. Hirji, MD, Dale C. Lien, MD, Jason C. Weatherald, MD, Kieran M. Halloran, MD

“…We tested the relationship between BLAD status and SF-36 physical component summaries and 6MWD using least squares regression, adjusting for age at transplant, sex at birth, and primary lung disease. …”
Get full text

Monocyte and Macrophage in Follicular Liquid: Predictive Markers of Embryo Quality in Women with Obesity and Infertility by Evgeny D. Merkulov, Anastasia V. Prozorova, Iuliia G. Samoilova, Dmitry A. Svarovsky, Kira A. Sidorenkova, Liudmila V. Spirina, Marina N. Stakheeva, Oxana S. Timofeeva, Ilya A. Petrov

“…Methods: The study involved 45 women with a mean age of 35 ± 4.66 years. Monocytes and macrophages were identified using flow cytometry. …”
Get full text

Efficacy and safety of super selective bronchial artery coil embolisation for haemoptysis: a single-centre retrospective observational study by Daijiro Kabata, Ayumi Shintani, Masanori Akira, Masahiko Hara, Hideo Ishikawa, Misaki Ryuge, Jun Takafuji, Mihoko Youmoto, Yukio Nagasaka, Kouji Yamamoto

“…Each component of the primary end point and procedural success defined as successful embolisation of all target HRAs were also evaluated.Results The median patient age was 69 years, and 46.4% were men. The total number of target vessels was 4 (quartile 2–7), and the procedural success rate was 93.4%. …”
Get full text

Protocol for Home-Based Solution for Remote Atrial Fibrillation Screening to Prevent Recurrence Stroke (HUA-TUO AF Trial): a randomised controlled trial by Jing Tan, Yan Liang, Yong Liu, Wei Jiang, Duo Huang, Ning Tan, Chung-Wah Siu, Jo Jo Hai, Xiaoyu Huang, Jianfeng Ye, Ji-yan Chen, Chun Ka Wong, Mi Zhou, Li-Xue Yin, Ming-Liang Zuo, Kui Kai Lau, Zhen Lei, Yingqing Feng, Bryan P Yan, Wen-Sheng Yue, Wen-Jun Zhang, Yuk-Ming Lau, Hin-Wai LUI, Koon-Ho Chan, Toi Meng Mok, Weng-Chio Tam, Kun-Chong Tam, Xiuhua Feng, Xiaofei Jiang, Guanming Tan, Mario Alberto Evora

“…The objective of the study was to explore the use of long-term home-based ECG monitoring for AF detection and stroke prevention in patients with a history of stroke.Methods and analysis This prospective, randomised, open-label trial with blinded endpoint adjudication aimed to evaluate the efficacy of long-term home-based ECG monitoring for AF detection and stroke prevention in a 24-month period. Patients aged >18 years with a history of ischaemic stroke will be stratified according to the time from the index ischaemic stroke: <1, 1–3 and >3 years and then randomised in 1:1 to (1) home-based AF screening and (2) control. …”
Get full text

A Standardized Classification Scheme for Gastroduodenal Disorder Evaluation Using the Gastric Alimetry System: Prospective Cohort Study by Chris Varghese, Gabriel Schamberg, Emma Uren, Stefan Calder, Mikaela Law, Daphne Foong, Vincent Ho, Billy Wu, I-Hsuan Huang, Peng Du, Thomas Abell, Charlotte Daker, Christopher N. Andrews, Armen A. Gharibans, Gregory O’Grady

“…Results: Two hundred ten patients were included (80% female, median age 37), of whom 169 met the criteria for chronic nausea and vomiting syndromes and 206 met the criteria for functional dyspepsia (79% meeting both criteria). …”
Get full text

Investigating Confined Space Asphyxias: Plastic Bag Involvement and Gas Inhalation – A Case Series and Literature Review by Sofija Saulė Kaubrytė, Sigitas Chmieliauskas, Giedrė Kažukauskė, Sigitas Laima, Diana Vasiljevaitė, Jurgita Stasiūnienė

“…Demographic analyses reveal distinct patterns, with younger age groups demonstrating an increased tendency for gas inhalation suicides. …”
Get full text