Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy by Jun Peng, Wenqi Zhao, Lu Zhou, Kun Ding

“…Also, VWF and ITGB2 were significantly related to the clinical features, including age, serum creatinine level, and GFR (MDRD). Besides, mRNA and protein expression levels of ITGB2 in HG-treated HK-2 cells were remarkably elevated. …”
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A multi-stakeholder collaborative approach to awareness, education and support needed in the haemophilia gene therapy patient journey – a report on insights from a European patient... by O’Mahony Brian, Fletcher Simon, Baarslag Manuel, Khair Kate, Breederveld Daan, Jansen Nathalie, Pembroke Luke, Pinachyan Karen, Sivasubramaniyam Sujan

“…The participants were 11 age-diverse men with severe haemophilia A or B, including six who had received gene therapy in phase 1-3 clinical trials. …”
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Comparison of Pocket Pulse Oximeter and Standard Pulse Oximeter With ABG Analysis in Critically Ill Patients by Jeswanth Reddy N., Kiran H. S., B. J. Subhash Chandra, Basavana Gowdappa H.

“…We compared the O2 saturations of ABG, SPO, and PPO with respect to sex, different age groups, and at different levels of ABG pCO2, HCO3, and pH in all patients. …”
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HIV viral load suppression rates among adults and children living with HIV in the North West Region of Cameroon: A call for action! by Gladys Fosah E Tayong, Melissa Sander, Comfort Vuchas, Moses Samje, Vera Kum, Pascal Enokbonong, Eugene Yeika, Ndanga Bekombo, Paul Nyibio, Vanessa B Ngwani, Justin Ndié, Njamnshi Wepnyu Yembe, Gloria Ashuntangtang

“…<h4>Introduction</h4>HIV continues to be a major public health problem in Cameroon where 2.7% of the population aged 15 to 49 are living with HIV. The prevalence remains higher in females, 3.4% versus 1.9% in males. …”
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The LIFTMOR-M (Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation for Men) trial: protocol for a semirandomised controlled trial of supervised targeted exerci... by Benjamin K Weeks, Belinda R Beck, Amy T Harding, Steven L Watson

“…Intervention group responses will be compared with those of a self-selected, non-randomised control sample of sex-matched and age-matched men who will follow their usual lifestyle activities for 8 months.Methods and analysis Apparently healthy men over 50 years with low bone mass, screened for medical conditions and medications known to adversely affect bone health, will be recruited. …”
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Assessing the Changes of Mumps Characteristics with Different Vaccination Strategies Using Surveillance Data: Importance to Introduce the 2-Dose Schedule in Quzhou of China by Chunting Zhou, Wei Song, Zhiying Yin, Sheng Li, Xiaoying Gong, Quanjun Fang, Shuangqing Wang

“…The highest incidence was in children aged 6-14 years from 2005-2016, of which the majority were school students (67.84%). …”
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Satisfied with the worst health outcomes or unsatisfied with the best: explaining the divergence between good patient-reported outcomes and low satisfaction and vice versa among kn... by Lukas Schöner, Viktoria Steinbeck, Reinhard Busse, Carlos J. Marques

“…Results A total of 1546 knee arthroplasty patients with a mean age of 65.9 years, 54.1% female, were included. 1146 (74.1%) patients were Satisfied Achievers, 131 (8.5%) were Dissatisfied Achievers, 141 (9.1%) were Satisfied Non-Achievers, and 128 (8.3%) Dissatisfied Non-Achievers. …”
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Combining systemic inflammation biomarkers with traditional prognostic factors to predict surgical site infections in elderly hip fracture patients: a risk factor analysis and dyna... by Yuhui Guo, Chengsi Li, Haichuan Guo, Peiyuan Wang, Xuebin Zhang

“…Multivariable analysis identified traditional prognostic factors older age (OR = 1.08, 95% CI 1.04–1.12), ASA class III-IV (OR = 2.46, 95% CI 1.32–4.56), surgical delay ≥ 6 days (OR = 3.59, 95% CI 1.36–9.47), surgical duration > 180 min (OR = 2.72, 95% CI 1.17–6.35), and systemic inflammation biomarkers Platelet-to-lymphocyte ratio (PAR) ≥ 6.6 (OR = 2.25, 95% CI 1.17–4.33) and Systemic Immune-Inflammation Index (SII) ≥ 541.1 (OR = 2.24, 95% CI 1.14–4.40) as independent predictors of SSI. …”
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Prevalence, correlates of postpartum depression during the COVID-19 pandemic; and validation of the arabic edinburgh postnatal depression scale among Lebanese women by Christian El Kahwaji, Elie Barakat, Feten Fekih-Romdhane, Camille Akkari, Savio Barakat, Souheil Hallit

“…Methods A cross-sectional study was conducted between May 2022 and July 2022, with 402 Lebanese adult postpartum women (mean age 31.46 ± 4.88 years) enrolled from the maternity ward at CHU-Notre Dame des Secours Hospital in Byblos, Lebanon by responding to an online survey after obtaining informed concent. …”
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Human exploitation of adult horseshoe crab and public awareness campaign in Hong Kong SAR, China by Pui Yi Tang, Hei Wut Fong, Shan Yee Lee, Wing Tung Chang, Lee Yan Pang, Tin Yan Hui, Kelvin Jun Yin So

“…However, such knowledge improved with an increased education level, particularly among those in the 50–59 age group and those who visited horseshoe crab habitats. …”
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Obesity in pregnancy: infant health service utilisation and costs on the NHS by Ronan A Lyons, Ashrafunnesa Khanom, Sinead T Brophy, Kelly L Morgan, Muhammad A Rahman, Rebecca A Hill

“…Costs are calculated as cost of the infant (no maternal costs considered) and are related to health service usage from birth to age 1 year.Results A strong association existed between healthcare usage cost and BMI (p&lt;0.001). …”
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Healthcare utilization and related costs among older people seeking primary care due to back pain: findings from the BACE-N cohort study by Danielle van der Windt, Milada Cvancarova Småstuen, Kjersti Storheim, Margreth Grotle, Zinajda Zolic-Karlsson, Ørjan Nesse Vigdal, Rikke Munk Killingmo, Lise Kretz

“…Objectives To describe healthcare utilization and estimate associated costs during 1 year of follow-up among older people seeking primary care due to a new episode back pain and to describe healthcare utilization across patients with different risk profiles stratified using the StarT Back Screening Tool (SBST).Design Prospective cohort study.Participants and setting A total of 452 people aged ≥55 years seeking Norwegian primary care with a new episode of back pain were included.Outcome measures The primary outcome of this study was total cost of healthcare utilization aggregated for 1 year of follow-up. …”
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“It's hard to talk to a computer, I get it”: An exploratory analysis of clinician connection-building communication practices in rural telepalliative care encounters by Elise C. Tarbi, Natalie Ambrose, Eric C. Anderson, Rebecca N. Hutchinson, Paul K.J. Han, Maija Reblin, Robert Gramling

“…Patient-participants had a mean age of 68 years, 56 % were women, and 38 % did not complete high school. …”
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Le site antique de la clinique des Dames Blanches à Tours (Indre-et-Loire) : aménagements d’un embarcadère romain sur la Loire et évolution du trait de rive by Nicolas Fouillet, Philippe Gardère

“…The funerary complex included at least 23 individuals: men, women and children of all ages, without any particular spatial distribution. …”
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“If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox by Sara Paparini, Rosalie Hayes, Benjamin Weil, Will Nutland, Ismael Maatouk, Teodora Wi, Chloe M. Orkin, Rosamund Lewis

“…Inclusion criteria were as follows: experience of mpox illness; age 18 and over; living in the United Kingdom (UK); living in the UK during 2022 mpox outbreak. …”
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A Nomogram Built on Clinical Factors and CT Attenuation Scores for Predicting Treatment Response of Acute Myeloid Leukemia Patients by Linna Liu, Wenzheng Lu, Li Xiong, Han Qi, Robert Peter Gale, Bin Yin

“…While clinical factors such as age and genetic mutations contribute to prognosis, recent studies suggest that CT attenuation scores may also predict treatment outcomes. …”
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The Plasma Soluble Urokinase Plasminogen Activator Receptor Is Related to Disease Activity of Patients with ANCA-Associated Vasculitis by Fei Huang, Yueqiang Li, Ranran Xu, Anying Cheng, Yongman Lv, Qingquan Liu

“…Besides, multivariate analyses confirmed that plasma suPAR levels were an independent adverse prognostic factor for a composite outcome of end-stage renal disease (ESRD) or death, after adjusting for age and gender (HR 1.05, 95% CI=1.01−1.11, P=0.043). …”
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Access Differentials in Primary Healthcare among Vulnerable Populations in a Health Insurance Setting in Kumasi Metropolis, Ghana: A Cross-Sectional Study by Gertrude Acquah-Hagan, Daniel Boateng, Emmanuel Appiah-Brempong, Peter Twum, Joseph Amankwa Atta, Peter Agyei-Baffour

“…This study was a descriptive cross-sectional study conducted among multilevel participants of vulnerable groups in Kumasi Metropolis: 710 vulnerable people constituting elderly/aged (n = 359), pregnant women (n = 117), head poters (teenage girls who migrated from the northern Ghana mainly to the capital cities of the Ashanti and Greater Accra region to help in carrying of goods for their livelihood) (n = 86), sex workers (n = 75), and other vulnerable groups (people with disabilities and street participants) (n = 73). …”
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Advancement of eco-friendly slag-based high-strength geopolymer concrete by Saeeb M. AL-Tam, Amr Riad, Nader Mohammed, Ali Al-Otaibi, Osama Youssf

“…Shrinkage of CA50, CW30, and GW50 mixes decreased by an average of 57%, 53%, and 79%, respectively, at all ages. Microstructure analyses revealed a dense and homogeneous matrix for these mixtures, confirming their compressive strength results and identifying them as ideal mixtures. …”
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Annexin V+ Microvesicles in Children and Adolescents with Type 1 Diabetes: A Prospective Cohort Study by Vibeke Bratseth, Hanna D. Margeirsdottir, Gemma Chiva-Blanch, Martin Heier, Svein Solheim, Harald Arnesen, Knut Dahl-Jørgensen, Ingebjørg Seljeflot

“…The cohort included type 1 diabetics (n=40) and healthy controls (n=40), mean age 14 years (range 11) at inclusion, randomly selected from the Norwegian Atherosclerosis and Childhood Diabetes (ACD) study. …”
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