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21661
The concept of natural genome reconstruction. Part 1. Basic provisions of the “natural genome reconstruction” concept. Changing the genome of hematopoietic stem cells using several...
Published 2024-11-01“…It is assumed that as a result of stochastic acts of homologous exchange, chromosome loci are corrected in hematopoietic stem cells that have acquired mutations during the existence of the organism, which are the cause of clonal hematopoiesis associated with old age. In this regard, there is a fundamental possibility of changing the hematopoietic status of hematopoietic stem cells in the direction of polyclonality and the original diversity of clones. …”
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21662
Risk Factors and Clinical Predictors of Suicidal Behaviors and Non-Suicidal Self-Injury Among Pediatric Psychiatry Emergency Admissions Pre- and Post-Pandemic: A Retrospective Coho...
Published 2025-01-01“…Methods: This retrospective cohort study analyzed data from 341 adolescents (aged 6–18 years) presenting to a Romanian pediatric psychiatry emergency department during the years 2019 (pre-pandemic) and 2022 (post-pandemic). …”
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21663
Adverse Events of the BCG (Bacillus Calmette–Guérin) and Rotavirus Vaccines in a Young Infant with Inborn Error of Immunity
Published 2020-01-01“…This young infant was diagnosed at six months of age with “immunodeficiency type 19” (MIM#615617) due to homozygous nonsense variant, NM_000732.4 (CD3D):c.128G > A, p.Trp43∗ (variation ClinVar#VCV000643120.1; pathogenic). …”
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21664
Barriers and facilitators of loaded self-managed exercises and physical activity in people with patellofemoral pain: understanding the feasibility of delivering a multicentred rand...
Published 2019-06-01“…The trial investigated a loaded self-managed exercise intervention, which included education and advice on physical activity versus usual physiotherapy as the control.Design Qualitative study, embedded within a mixed-methods design, using semi-structured interviews.Setting A UK National Health Service physiotherapy clinic in a large teaching hospital.Participants Purposively sampled 20 participants within a feasibility RCT study; 10 patients with a diagnosis of patellofemoral pain, aged between 18 and 40 years, and 10 physiotherapists delivering the interventions.Results In respect to barriers and facilitators, the five overlapping themes that emerged from the data were: (1) locus of control; (2) belief and attitude to pain; (3) treatment expectations and preference; (4) participants’ engagement with the loaded self-managed exercises and (5) physiotherapists’ clinical development. …”
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21665
Enhancing physical fitness through Crossfit for 15-16-year-old high school students
Published 2024-06-01“…The study involved 27 students (aged 15-16 years) from a 10th-grade class at a school located in a war conflict zone (Kharkiv, Ukraine). …”
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21666
Longitudinal association between hemoglobin and lung function with insights into the incidence of airflow obstruction: an observational study
Published 2025-01-01“…Results Over an 8-year biennial follow-up of 4,468 individuals (median age, 53.9 years; men, 49.0%), we observed that in men, Hb levels were positively associated with lung function (estimated values of FVC: 16.7 mL, FEV1: 15.5 mL, FEV1/FVC: 0.18%; all P < 0.001) and a decreased incidence of AO (OR = 0.83, P < 0.001). …”
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21667
Emissions of Nitrous Oxide and Nitric Oxide from Soils of Native and Exotic Ecosystems of the Amazon and Cerrado Regions of Brazil
Published 2001-01-01“…As in Amazonian pastures, NO emissions appear to decline with pasture age. Detectable emissions of N2O have been measured in soybean and corn fields in the Cerrado region, but they are modest relative to fluxes measured in more humid tropical agricultural regions. …”
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21668
Zinc Supplementation Prevented Type 2 Diabetes-Induced Liver Injury Mediated by the Nrf2-MT Antioxidative Pathway
Published 2021-01-01“…A high-fat diet, along with a one-time dose of streptozotocin, was applied to metallothionein (MT) knockout mice, nuclear factor-erythroid 2-related factor (Nrf) 2 knockout mice, and age-matched wild-type (WT) control mice, in order to induce type 2 diabetes. …”
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21669
Clinical Features and Prognosis Analysis of Hormone Receptor-Positive, HER2-Negative Breast Cancer with Differential Expression Levels of Estrogen and Progesterone Receptors: A 10-...
Published 2022-01-01“…L group patients had significantly more stage N2 axillary lymph nodes than H group patients (31.8% vs. 9.2%, P = 0.007). Age (P = 0.011), menopause status (P = 0.001), and tumor size (P = 0.024) were significantly different in the HL vs. …”
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21670
Performance of a Toric, Monthly, Soft Contact Lens in Digital Device Users
Published 2025-01-01“…Subjects were evaluated at 1 month with the Computer Vision Syndrome Questionnaire (CVS-Q), Impact of Dry Eye on Everyday Life (IDEEL) Quality of Life questionnaire, and a custom questionnaire.Results: A total 48 subjects were analyzed (mean age = 28.8 ± 6.3 years; 75% female). At 1 month, IDEEL daily activities, feelings, and work domains scores were 96.7 ± 6.6, 96.4 ± 6.2, and 94.8 ± 8.6, respectively. …”
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21671
Factors Affecting Performance in Clinical Practice among Preservice Diploma Nursing Students in Northern Tanzania
Published 2019-01-01“…Reporting of barriers to effective clinical learning by students from different schools of nursing was not significant (P=0.696). In addition, age of participants did not have significant association with effective clinical practice (p=0.606). …”
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21672
Knowledge about COVID-19 and Practices among Hemodialysis Technicians in the COVID-19 Pandemic Era
Published 2020-01-01“…Out of 150, 115 technicians participated in the survey. 80.9% of the participants were males. The mean age of respondents was 28.22 + 6.97 years. Most of the respondents could correctly identify fever (87.8%), breathlessness (86.08%), and dry cough (81.7%) as the symptoms of COVID-19 infection. 75.7% of the technicians were aware that it can be transmitted by asymptomatic persons. 61.1% of the technicians were segregating patients who had symptoms such as fever and cough to the last shift of the day. 81.1% of the technicians read the guidelines issued by the Indian Society of Nephrology—COVID-19 working group. …”
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21673
Insulin therapy adherence and its associated factors among diabetic patients in a Ghanaian primary care hospital.
Published 2025-01-01“…Adherence level was associated with age (p = 0.020), marital status (p = 0.001), employment status (p = 0.012), type of DM (p<0.001), regular follow-up (p = 0.007) and comorbidities (p = 0.002) and was only predicted by the type of DM (aOR = 14.82 C.I 1.34-163.50, p-value = 0.028).…”
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21674
Body Composition Changes and Associations in Infants and Mothers During the First Year: Insights from a Pilot Study of the Baby-bod Project
Published 2025-01-01“…While the findings of our pilot study underscore the importance of encouraging women of childbearing age to maintain a healthy BMI before conception, further research is needed to substantiate these results.…”
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21675
The COVID-19 pandemic and self-reported food insecurity among women in Burkina Faso: evidence from the performance monitoring for action (PMA) COVID-19 survey data
Published 2025-02-01“…This study examined the associations between socioeconomic variables, such as age, education, household income loss, and food insecurity. …”
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21676
Choroidal thickness under pilocarpine versus cyclopentolate
Published 2025-01-01“…The study included 21 healthy individuals (age:21.9 ± 2.6 years; range:15.7–25.8 years; axial length:24.4 ± 1.2 mm). …”
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21677
The survey of the status of self-stigma of depression and its relationship with demographic factors in Gonabad, Iran
Published 2024-11-01“…There were no significant relationships between education level, economic status, age group, occupation, and marital status with SSD (p > 0.05). …”
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21678
Improvement in the effective cataract surgical coverage in Malaysia: evidence of impact from a mobile cataract outreach program
Published 2025-02-01“…It involved a multistage cluster sampling method, each cluster comprising 50 residents aged 50 years and older. Presenting visual acuity (PVA) was checked, and subjects with cataracts were identified. …”
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21679
Correlation Between Spinopelvic Parameters, Body Mass Index, Waist Circumference, and Chronic Non-Specific Low Back Pain
Published 2024-12-01“…Results: We included 272 patients (male–female ratio, 1.08) with a mean age of 54 years. There was a statistically significant difference (<i>p</i> < 0.05) in the mean PI according to BMI group. …”
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21680
Effect of Isoniazid Preventive Therapy on the Incidence of Tuberculosis among Seropositive Children Attending HIV/AIDS Care in Two General Hospitals, Northwest Ethiopia, 2021
Published 2021-01-01“…Missed IPT (AHR = 7.45, 95% CI: 2.96, 18.74, P<0.001), missed cotrimoxazole preventive therapy (CPT) (AHR = 2.4, 95% CI: 1.84–4.74, P<0.022), age ≥ 11 years (AHR = 4.2, 95% CI: 1.04–7.03, P<0.048), MUAC ≤ 11.5 cm (AHR = 4.36, 95% CI: 1.97–9.97, P<0.001), WHO stages III and IV (AHR = 2.04, 95% CI: 1.12–3.74, P<0.022), and CD4 count ≤100 cells/μl (AHR = 3.96, 95% CI: 1.52–10.34, P<0.005) were significantly associated with TB incidence. …”
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