Polymorphic variants of the <i>hOGG1, APEX1, XPD, SOD2</i>, and <i>CAT</i> genes involved in DNA repair processes and antioxidant defense and their association with breast cancer r... by А. А. Timofeeva, V. I. Minina, A. V. Torgunakova, О. А. Soboleva, R. А. Тitov, Ya. А. Zakharova, M. L. Bakanova, А. N. Glushkov

“…In the group of elderly women (aged 60–74 years), an association of the CAT gene polymorphism with the risk of developing luminal B subtype of breast cancer was found in a log-additive inheritance model (OR = 1.87; 95 % CI: 1.22–2.85; Padj = 0.0024). …”
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Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

“…Significant predictors of migration included younger age, timing of marriage, and residency training status. …”
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Prediction of Cisplatin‐Induced Acute Kidney Injury Using an Interpretable Machine Learning Model and Electronic Medical Record Information by Kaori Ambe, Yuka Aoki, Miho Murashima, Chiharu Wachino, Yuto Deki, Masaya Ieda, Masahiro Kondo, Yoko Furukawa‐Hibi, Kazunori Kimura, Takayuki Hamano, Masahiro Tohkin

“…This single‐center retrospective study included hospitalized patients aged ≥ 18 years who received the first course of cisplatin chemotherapy from January 1, 2011, to December 31, 2020, at Nagoya City University Hospital. …”
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Relationships between the menstrual cycle and neuropsychiatric and physical symptoms in females with Tourette syndrome by Daisy T. Noriega-Makarskyy, Evan Realbuto, Ariadne Kaylor, Lisa Osiecki, Angela Essa, Dongmei Yu, Dongmei Yu, Cornelia Illmann, Carol A. Mathews, Carol A. Mathews, Carol A. Mathews, Jeremiah M. Scharf, Jeremiah M. Scharf, Jeremiah M. Scharf, Jeremiah M. Scharf, Jeremiah M. Scharf

“…Respondents were asked to share their age of TS symptom onset, history of OCD and ADHD diagnoses, and current tic symptoms and severity. …”
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Immunotherapy in metastatic renal cell carcinoma: Insights from a Dutch nationwide cohort by Hilin Yildirim, Anke Richters, Adriaan D. Bins, Arnoud W. Postema, Maureen J.B. Aarts, Martijn G.H. van Oijen, Patricia J. Zondervan, Katja K.H. Aben

“…Patients diagnosed with synchronous mRCC between 2018 and 2022 were identified from the population-based Netherlands Cancer Registry (n = 2621). The median age was 70 yr and 58% of patients had clear-cell RCC. …”
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Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) by Qingyang Zhu, Yuebin Lyu, Keyong Huang, Jinhui Zhou, Wenhao Wang, Kyle Steenland, Howard H. Chang, Stefanie Ebelt, Xiaoming Shi, Yang Liu

“…These findings underscore the imperative for the next iteration of China's Air Pollution Prevention and Control Action Plan to broaden its focus to encompass gaseous air pollutants since mitigating single air pollutant is insufficient to protect the aging population.…”
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Determinants of Work-Related Risks among Veterinary Clinical Students in South West Nigeria by Oluwawemimo O. Adebowale, Monsurat O. Afolabi, Hezekiah K. Adesokan, Olubunmi G. Fasanmi, Olanike K. Adeyemo, Olajoju J. Awoyomi, Folorunso O. Fasina

“…Of 167 students recruited, 100 (60.2%) were males, and >77.1% fell within the age group of 21–25 years. Many participants (77.0%) reported the lack of active HS committee. …”
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Eculizumab treatment for Chinese patients with hemolytic paroxysmal nocturnal hemoglobinuria (PNH): efficacy and safety – a single-center study by Leyu Wang, Ziwei Liu, Chen Yang, Miao Chen, Bing Han

“…The incidence rates of breakthrough hemolysis (BTH), extravascular hemolysis (EVH), and adverse events were recorded.Result A total of 48 patients, including 27 males, with a median age of 46 (12–78) years were included. Twenty-four (50%) patients had classic PNH and 24 (50%) had bone marrow failure (BMF)/PNH. …”
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Histone Arginine Methylation-Mediated Epigenetic Regulation of Discoidin Domain Receptor 2 Controls the Senescence of Human Bone Marrow Mesenchymal Stem Cells by Zhenyu Xu, Wenming Wu, Fang Shen, Yue Yu, Yue Wang, Charlie Xiang

“…Herein, we compared the gene expression profiles of human embryonic stem cells and human BM-MSCs from donors of different ages. We first found that the expression of discoidin domain receptor 2 (DDR2) in adult donor-derived hBM-MSCs was lower than it was in the young donor-derived hBM-MSCs. …”
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Novel Role of Pin1-Cis P-Tau-ApoE Axis in the Pathogenesis of Preeclampsia and Its Connection with Dementia by Emmanuel Amabebe, Zheping Huang, Sukanta Jash, Balaji Krishnan, Shibin Cheng, Akitoshi Nakashima, Yitong Li, Zhixong Li, Ruizhi Wang, Ramkumar Menon, Xiao Zhen Zhou, Kun Ping Lu, Surendra Sharma

“…This review will also cover genetic polymorphisms in the ApoE alleles leading to dyslipidemia induction that may regulate the pathways causing preE or dementia-like features in the reproductive age or later in life, respectively.…”
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A Prospective Randomized Study for Comparison of Modified Proximal Femoral Plate with Dynamic Hip Screw System by Jitendra Wadhwani, Ramchander Siwach, Himanshu Bansal, Roop Singh, Pradeep Kamboj, Hemant More

“…Randomization was done using the lottery method. The mean age was 65.66 years (range, 28–90) and 64.07 years (range, 31–90) in the DHS group and PFLCP group, respectively. …”
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Clinical characteristics and outcomes of children with COVID-19 in pediatric intensive care units during the Omicron wave in Taiwan by Jeng-Hung Wu, Ching-Chia Wang, Frank Leigh Lu, Shu-Chien Huang, Ting-Yu Yen, Chun-Yi Lu, Luan-Yin Chang, En-Ting Wu

“…Methods: Medical records were retrospectively collected from patients with COVID-19 (aged <18 years) admitted to our PICU from April 2022–March 2023. …”
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Evolution of Liver Resection for Hepatocellular Carcinoma: Change Point Analysis of Textbook Outcome over Twenty Years by Yeshong Park, Ho-Seong Han, Seung Yeon Lim, Hyelim Joo, Jinju Kim, MeeYoung Kang, Boram Lee, Hae Won Lee, Yoo-Seok Yoon, Jai Young Cho

“…More recent time interval groups were associated with older age (59 vs. 59 vs. 61 vs. 63 years, <i>p</i> < 0.0001) and more comorbidities. …”
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The clinical value of Serum hyaluronic acid, procollagen III, N-terminal propeptide levels sST2 and cfDNA in predicting the myocardial damage in children with severe pneumonia by Haoran Jia, Ye Liu, Tingting Zhao, Dexing Wang, Meng Du, Weiwei Wang

“…Results: Logistic regression analysis identified hypoalbuminaemia, age <3 years, and elevated levels of serum hyaluronic acid, procollagen III N-terminal propeptide, sST2, and cfDNA as independent risk factors for myocardial damage. …”
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The Analysis of the Fetal Abdominal Wall and Gastrointestinal Tract Abnormalities in a Single Tertiary Center by Gokhan Bolluk, Suleyman Cemil Oglak, Merih Cetinkaya, Isil Turan Bakirci, Oyhan Demirali, Mehmet Cok, Handan Turhan Karakus, Yasin Onur, Emine Zeynep Yilmaz

“…RESULTS: A total of 67 cases were included in our study with a mean maternal age of 26.4 ± 3.1 years and a median gestational week of first assessment at our center of 22 weeks (12-39 weeks). …”
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Impaired Hepatitis B and COVID-19 vaccination responses show strong concordance in hemodialysis patients with end stage renal disease by Karsten Lürken, Anna Meinecke, Luis A. Manthey, Anne Cossmann, Metodi V. Stankov, Frank Klawonn, Anna Zychlinsky Scharff, Sandra Steffens, Alexandra Dopfer-Jablonka, Frank Müller, Georg M. N. Behrens, Christine Happle

“…HBV vaccination non-responsiveness, but not poor SARS-CoV-2 post-vaccination immunity was associated with obesity, while poor SARS-CoV-2 vaccination responses were associated increased age. Conclusion Our findings confirm previous reports on impaired vaccination response in hemodialysis patients and show that post-vaccination humoral responses against SARS-CoV-2 and HBV display strong overlap in this vulnerable patient group. …”
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Technical Proficiency Analysis in Table Tennis: A Comparative Study Between Advanced and Intermediate Players by Benny Aprial, Denny Setyawan, George Danut Mocanu, Candra Brema Tarigan, Ghulam Mustafa, John Michael D. Aquino, Bilal Azmi Sarıtaş

“…The research involved 40 participants (20 advanced players with 5+ years of competitive experience and 20 intermediate players with 2-4 years of experience) aged 18-25 years. Over a three-month period, participants underwent systematic evaluation of their technical skills, including basic stroke accuracy, biomechanical efficiency, and tactical adaptability. …”
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Clinical significance of establishing a red blood cell alloantibody detection database by XIAO Xiao, CHEN Long, ZHAO Zhenyu, HE Zhanghan, ZHOU Mengjun, TANG Jie

“…In the univariate analysis, the positivity of antibody was significantly associated with the patient's gender, age, blood transfusion history, pregnancy history and type of disease (all P<0.001). …”
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Risk factors for electroconvulsive therapy-induced fever: a retrospective case-control study by Can-Jin Deng, Can-Jin Deng, Jian-Wen Yang, Jian-Wen Yang, Zi-Zhe Liu, Zi-Zhe Liu, Ting Ning, Ting Ning, Sha Nie, Sha Nie, Xiong Huang, Xiong Huang, Xin-Hu Yang, Xin-Hu Yang, Xing-Bing Huang, Xing-Bing Huang, Wei Zheng, Wei Zheng

“…However, little is known about the prevalence of ECT-induced fever and its associated risk factors in patients with major mental disorders (MMD).MethodsThis retrospective, case-control study included 113 cases and 226 age-matched controls (1:2). The case group comprised patients who exhibited an axillary temperature of ≥37.5°C (99.5°F) at least once within 24 hours post-ECT. …”
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The effect of failed transfer of passive immunity and agammaglobulinemia on the occurrence of preweaning diarrhea, pneumonia, and mortality in Holstein calves by Mely T. Olivera, Jesús Mellado, José E. García, Juan A. Encina, Perpetuo Álvarez, Ulises Macías-Cruz, Leonel Avendaño, Miguel Mellado

“…The odds of dying before 60 days of age were 1.9 times higher in calves with FPI. …”
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