Clinical Characteristics in Patients with Triple Negative Breast Cancer by Janet Yeh, Jennifer Chun, Shira Schwartz, Annie Wang, Elizabeth Kern, Amber A. Guth, Deborah Axelrod, Richard Shapiro, Freya Schnabel

“…There was a significantly higher proportion of African American and Asian patients with TNBC (p=0.0003) compared to patients with non-TNBC. …”
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Proteomic profiling identifies upregulation of aurora kinases causing resistance to taxane-type chemotherapy in triple negative breast cancer by Bohan Ning, Chang Liu, Ali Cem Kucukdagli, Jiuyi Zhang, Han Jing, Zhiqian Zhou, Yuwei Zhang, Ying Dong, Yunjia Chen, Hua Guo, Jia Xu

“…In our UAB TNBC cohort, the expression of AURKA and AURKB was significantly higher in TNBC tumors compared to normal adjacent tissues, and AURKB was found to be highly expressed in African American TNBC patients compared to European Americans. …”
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Effect of Intensive Blood Pressure Control on Cardiovascular Remodeling in Hypertensive Patients with Nephrosclerosis by Otelio Randall, John Kwagyan, Tamrat Retta, Kenneth Jamerson, Velvie Pogue, Keith Norris, Muluemebet Ketete, Shichen Xu, Tom Greene, Xuelei Wang, Lawrence Agodoa

“…We studied 1094 nondiabetics with nephrosclerosis in the African American Study of Kidney Disease and Hypertension. …”
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Attitudes toward Management of Sickle Cell Disease and Its Complications: A National Survey of Academic Family Physicians by Arch G. Mainous, Rebecca J. Tanner, Christopher A. Harle, Richard Baker, Navkiran K. Shokar, Mary M. Hulihan

“…There were significant differences in comfort level for treatment of SCD patients depending on whether or not physicians had patients who had SCD, as well as physicians who had more than 10% African American patients. Physicians also felt that clinical decision support (CDS) tools would be useful for treatment (69.4%) and avoiding complications (72.6%) in managing SCD patients. …”
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Malignant Course of Anomalous Left Coronary Artery Causing Sudden Cardiac Arrest: A Case Report and Review of the Literature by Mahesh Anantha Narayanan, Christopher DeZorzi, Abhilash Akinapelli, Toufik Mahfood Haddad, Aiman Smer, Janani Baskaran, William P. Biddle

“…We present a case of sudden cardiac arrest caused by anomalous left anterior descending artery. 61-year-old African American female was brought to the emergency department after sudden cardiac arrest. …”
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Impacts of stigma and discrimination on people with obesity who smoke cigarettes by Liza A. Kolbasov, Arryn A. Guy, Cara M. Murphy

“…Participants (N = 63; predominantly women (81.0 %), White (63.5 %) or Black/African American (31.7 %), and heterosexual (85.7 %) with 50 % having a yearly income below $50,000) completed the measures of stigma (i.e., Weight Bias Internalization Scale and Internalized Stigma of Smoking Inventory), discrimination (i.e., Everyday Discrimination Scale), and symptoms of depression, weight, smoking, nicotine dependence, and concerns about gaining weight while quitting smoking were measured. …”
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A Novel Use of Early Radiation Therapy in the Treatment of Hyperbilirubinemia in a Patient with Primary Hepatic Lymphoma and Chronic Hepatitis C by Venkata S. Tammana, Rehana Begum, Patricia Oneal, Hemamalini Karpurapu, Amruta Muley, Sri Lakshmi Hyndavi Yeruva, Jacquelyn Dunmore-Griffith, Eyasu Mekonen, Nabhani Hasan

“…Here, we describe a case of Hepatitis C virus infection with primary hepatic lymphoma (PHL) presenting with hyperbilirubinemia. A 45-year-old African American male presented with abdominal pain, pruritus, and itching for two days. …”
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Social, Racial, and Economic Disparities Affecting Outcomes of Hypertensive Adolescents by Kanya Singhapakdi, Amelia Haydel, Marla Johnston, Shengping Yang, Tamara Bradford, Dedrick Moulton, Thomas R. Kimball

“…In this study, more social vulnerability and low income were associated with a greater indexed LV mass (r = 0.18, p = 0.008). African American race was associated with a higher left atrial (LA) volume (p = 0.03). …”
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Protective Effects of BDNF against C-Reactive Protein-Induced Inflammation in Women by Nicole Noren Hooten, Ngozi Ejiogu, Alan B. Zonderman, Michele K. Evans

“…We examined BDNF levels in 3 groups of women that were age- and race-matched with low (<3 mg/L), mid (>3–20 mg/L), and high (>20 mg/L) hsCRP (n=39 per group) and found a significant association between hsCRP, BDNF, and 8-oxodG. In African American females with high hsCRP, increases in BDNF were associated with decreased serum 8-oxodG. …”
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Nontyphi Salmonella Empyema with Bronchopleural Fistula in a Patient with Human Immunodeficiency Virus by Douglas Bretzing, Tasnim Lat, Andrew Shakespeare, Mary Lee, Salim Surani, Shekhar Ghamande

“…Case Presentation. A 40-year-old African American male with HIV noncompliant with HAART therapy presented with complaints of generalized weakness, weight loss, cough, night sweats, and nonbloody, watery diarrhea of four weeks’ duration. …”
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Biomonitoring PhIP, a Potential Prostatic Carcinogen, in the Hair of Healthy Men of African and European Ancestry by Robert J. Turesky, Clarence Jones, Jingshu Guo, Kari Cammerrer, Laura A. Maertens, Emmanuel S. Antonarakis, Zhanni Lu, Logan G. Spector

“…Frequent consumption of well-done meats containing 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine (PhIP), a prevalent HAA that is a prostatic carcinogen in rodents and DNA-damaging agent in human prostate cells, has been linked to aggressive prostate cancer (PC) pathology. African American (AA) men face nearly twice the risk for developing and dying from PC compared to White men. …”
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Reaching back to enhance the future: the American Association for the Surgery of Trauma Diversity, Equity and Inclusion Pipeline Program by Sharon M Henry, Karen J Brasel, Cherisse Berry, Bethany Lauren Strong, Latoya Silverton, William Wical

“…The pre-workshop and post-workshop and 6-month follow-up surveys were analyzed for mentee experience and areas for improvement.Results Mentees selected were 30% male (N=3 of 10), 70% female (N=7 of 10), 50% black or African American (N=5 of 10) and 30% Hispanic or Latinx (N=3 of 10). …”
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Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA) by Wei Zhao, Lisha Lin, Kristen M. Kelly, Lauren A. Opsasnick, Belinda L. Needham, Yongmei Liu, Srijan Sen, Jennifer A. Smith

“…To identify the DNAm sites across the epigenome that are associated with discrimination, we conducted epigenome-wide association analyses (EWAS) of three discrimination measures (everyday discrimination, race-related major discrimination, and non-race-related major discrimination) in 1,151 participants, including 565 non-Hispanic White, 221 African American, and 365 Hispanic individuals, from the Multi-Ethnic Study of Atherosclerosis (MESA). …”
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Racial and Socioeconomic Disparities in Out-Of-Hospital Cardiac Arrest Outcomes: Artificial Intelligence-Augmented Propensity Score and Geospatial Cohort Analysis of 3,952 Patients by Dominique J. Monlezun, Alfred T. Samura, Ritesh S. Patel, Tariq E. Thannoun, Prakash Balan

“…Of 3,952 OHCA patients across 38 hospitals, African Americans were the most likely to suffer OHCA despite representing a significantly lower percentage of the population (42.6 versus 22.8%; p<0.001). …”
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Do The Facts of Voting Rights Support Chief Justice Roberts’s Opinion in Shelby County? by Morgan Kousser

“…While acknowledging the success of the law in greatly increasing the number of African-American and Latino elected officials, Chief Justice John Roberts contended in his majority opinion in Shelby County v. …”
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DNA methylation profiling at base-pair resolution reveals unique epigenetic features of early-onset colorectal cancer in underrepresented populations by Jason Sheng Li, Karen Riggins, Li Yang, Chaorong Chen, Patricia Castro, Wedad Alfarkh, Neda Zarrin-Khameh, Michael E. Scheurer, Chad J. Creighton, Benjamin Musher, Wei Li, Lanlan Shen

“…Here, we construct comprehensive profiles of EOCRC DNA methylomes at base-pair resolution for a cohort of Hispanic and African American patients. Results We show the epigenetic landscape of these EOCRC patients differs from that of late-onset colorectal cancer patients, and methylation canyons in EOCRC tumor tissue preferentially overlapped genes in cancer-related pathways. …”
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A Rare Case of Colonic Sarcoidosis Presenting as a Mass by Haozhe Sun, Jasbir Makker, Harish Patel, Nikhitha Mantri, Ali N. Hussain, Naeem Abbas

“…We present a case of a 24-year-old African American man who was evaluated for persistent abdominal pain, chronic diarrhea, and weight loss. …”
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Reducing Colorectal Cancer Incidence and Disparities: Performance and Outcomes of a Screening Colonoscopy Program in South Carolina by Sudha Xirasagar, Yi-Jhen Li, James B. Burch, Virginie G. Daguisé, Thomas G. Hurley, James R. Hébert

“…This study evaluated the efficiency, effectiveness, and racial disparities reduction potential of Screening Colonoscopies for People Everywhere in South Carolina (SCOPE SC), a state-funded program for indigent persons aged 50–64 years (45–64 years for African American (AA)) with a medical home in community health centers. …”
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Disparities in Opioid Use Disorder Treatment Admissions in the United States by Peter J. Mallow, Michael Mercado, Michael Topmiller

“…In Cincinnati, there were 3102 Caucasian, 123 African American, and 73 Other admissions. The fully saturated model results found that Caucasians and Other had an increased likelihood of receiving planned medication-assisted therapy (OR 1.89, P value 0.039; OR 7.07, P value 0.002, respectively) compared to African Americans. …”
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Lifespan cardiometabolic exposures are associated with midlife white matter microstructure: The Bogalusa Heart Study by Reagan Dugan, Sreekrishna Ramakrishnapillai, Julia St Amant, Kori Murray, Kevin McKlveen, Maryam Naseri, Kaitlyn Madden, Lydia Bazzano, Owen Carmichael

“…Results: In both organized and diffuse white matter, age was associated with worse diffusion metrics, women had better diffusion metrics than men, and African American participants had worse diffusion metrics compared to White participants. …”
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