Fractal cycles of sleep, a new aperiodic activity-based definition of sleep cycles by Yevgenia Rosenblum, Mahdad Jafarzadeh Esfahani, Nico Adelhöfer, Paul Zerr, Melanie Furrer, Reto Huber, Famke F Roest, Axel Steiger, Marcel Zeising, Csenge G Horváth, Bence Schneider, Róbert Bódizs, Martin Dresler

“…We found that fractal and classical cycle durations (89±34 vs 90±25 min) correlated positively (r=0.5, p<0.001). Children and adolescents had shorter fractal cycles than young adults (76±34 vs 94±32 min). …”
Get full text

Advances in genetic diagnosis and therapy of hereditary heart disease: a bibliometric review from 2004 to 2024 by Huixi Ma, Yun Wang, Yang Jia, Linjun Xie, Lini Liu, Dingyi Zhang, Xinyue Ma, Yingkun Guo, Rong Xu

“…Bibliometric analysis software (CiteSpace 6.3.R1, VOSviewer 1.6.18, and Scimago Graphica) was used to analyze the general information, trends, and emerging foci of HHD in the past 20 years, including author, country, institution, keyword, and so on. …”
Get full text

Age-related differences in long-term potentiation-like plasticity and short-latency afferent inhibition and their association with cognitive function by Tong Wang, Ying Shen, Tianjiao Zhang, Chuan He, Qian Lu, Jie Song, Manyu Dong, Yilun Qian, Sisi Huang, Jing Teng

“…The neurophysiological assessment included LTP-like plasticity and SAI.Results The findings of this study revealed a decline in LTP among the older adults compared with the younger adults (wald χ2=3.98, p=0.046). …”
Get full text

Relationship between TyG-related index and hearing loss in people over 45 s in China by Chao Wang, Mengdi Shi, Liangzhen Xie, Chenhao Jiang, Yunxin Li, Jingxiao Li, Shulin Li, Yan Li

“…The results suggest that as the population ages, higher BMI and TyG-BMI indices may increase the risk of hearing impairment.ConclusionWhile the TyG index does not show a significant link to hearing loss, higher BMI and TyG-BMI indices are associated with an increased risk of hearing loss, especially in older adults. These findings highlight the importance of considering aging-related factors in public health initiatives aimed at preventing hearing loss. …”
Get full text

Artificial intelligence for the detection of acute myeloid leukemia from microscopic blood images; a systematic review and meta-analysis by Feras Al-Obeidat, Wael Hafez, Wael Hafez, Asrar Rashid, Mahir Khalil Jallo, Munier Gador, Ivan Cherrez-Ojeda, Ivan Cherrez-Ojeda, Daniel Simancas-Racines

“…We used the “metafor” and “metagen” libraries in R to analyze the different models used in the studies. …”
Get full text

Psychological interventions for inflammatory bowel disease: a systematic review and component network meta-analysis protocol by Antje Timmer, Gerta Rücker, Natalia Tiles-Sar, Johanna Neuser, Dominik de Sordi, Anne Baltes, Jan Preiss, Gabriele Moser

“…We will conduct NMA (all treatments will constitute single nodes of the network) and CNMA (we will define all treatments as sums of core components, eg, cognitive +behaviour, or cognitive +behaviour + relaxation, and additionally consider interactions) using the R Package netmeta.Ethics and dissemination No ethical approval is required. …”
Get full text

Antifungal, Insecticidal, and Repellent Activities of Rosmarinus officinalis Essential Oil and Molecular Docking of Its Constituents against Acetylcholinesterase and β-Tubulin by Ghizlane Houzi, Youness El abdali, Ghada Beniaich, Mohamed Chebaibi, Mohamed Taibi, Amine Elbouzidi, Samiha Kaioua, Abdeslam Asehraou, Mohamed Addi, Khalid Chaabane, Rachid Flouchi, Aimad Allali, Soad Khal-Layoun

“…The analysis revealed a total of sixteen components in R. officinalis EO, with 1,8-cineole (40.80%) being the major constituent, followed by α-pinene (26.18%) and camphor (19.53%). …”
Get full text

Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review by Mariana Herrera, Cristian Vera, Yoav Keynan, Zulma Vanessa Rueda

“…Spanish, English, and Portuguese articles comparing the concentration of IP associated with LTBI, either in plasma/serum or in vitro, in adults and nonimmunocompromised versus individuals with TB or without M. tuberculosis infection between 2006 July and 2018 July were included. …”
Get full text

Triatoma venosa and Panstrongylus geniculatus challenge the certification of interruption of vectorial Trypanosoma cruzi transmission by Rhodnius prolixus in eastern Colombia. by Omar Cantillo-Barraza, Lídia Gual-González, Natalia Velásquez-Ortiz, Manuel Alfonso Medina Camargo, Paola González, Lissa Cruz-Saavedra, Adriana Castillo, Sara Zuluaga, Giovanny Herrera, Hanson Cowan, Andrés Velez-Mira, Luz Helena Patiño, Juan David Ramírez, Omar Triana, Melissa S Nolan

“…Most infected humans were adults between the ages of 55 and 85 years old. No evidence of T. cruzi DNA was found using qPCR in human blood samples, but we found high parasitemia levels in the infected dogs. …”
Get full text

Study on the potential diagnostic value of metabolomics changes in different biological fluids for aspiration pneumonia by Lianghui Chen, Yazhen Chen, Fansen Lin, Jianbao Wang, Hongzhi Gao, Yuqi Liu

“…This condition is particularly common in older adults and individuals with impaired swallowing or consciousness. …”
Get full text

A Prospective Observational Study to Establish a Correlation Between Tinnitus and Hearing Loss by Anshu Chopra, Madhurima Bannerjee, Sanjoy Ghosh

“… Introduction: The prevalence of tinnitus in adults with hearing problems is very high (59 - 86%). …”
Get full text

1990–2041 Global burden of Burkitt lymphoma with 20 years forecast: A systematic analysis using the global burden disease of study of 2021 by Chengyun Dou, Yidan Sang, Hongbo Zhu, Chuangjie Cao

“…Conclusion: The burden of Burkitt lymphoma varies according to different regions and genders, and children of 0–14 years, adults of 50–74 years with Burkitt lymphoma disease as well as male patients need special attention. …”
Get full text

Cannabis related side effects in otolaryngology: a scoping review by Jobanjit S. Phulka, Joel W. Howlett, Amanda Hu

“…(PROSPERO: CRD42020153022). English studies in adults were included from inception to the end of 2019. …”
Get full text

Strawberry dietary intervention influences diversity and increases abundances of SCFA-producing bacteria in healthy elderly people by Franziska Meiners, Bernd Kreikemeyer, Patrick Newels, Ingmar Zude, Michael Walter, Alexander Hartmann, Daniel Palmer, Georg Fuellen, Israel Barrantes

“…We examined the effects of a strawberry-based intervention on the gut microbiome of 69 healthy elderly German adults. Participants in five groups consumed varying amounts of strawberries, freeze-dried strawberries, and capers in olive oil over 10 weeks as part of a randomized controlled trial. 16S rRNA sequencing was used to analyze differences in microbial composition, diversity, phenotypes, differential abundance, and functional pathways. …”
Get full text

The relationship between activities of daily living and speech impediments based on evidence from statistical and machine learning analyses by Liu Jun, Hongguo Li, Yu Mao, Lan Hu, Dan Wu

“…IntroductionSpeech impediments (SIs) are increasingly prevalent among middle-aged and older adults, raising concerns within public health. Early detection of potential SI in this demographic is critical. …”
Get full text

Global, regional and national epidemiological trends of multiple myeloma from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021 by Linmin Zhuge, Xiaowu Lin, Ziwei Fan, Mengxian Jia, Chaowei Lin, Minyu Zhu, Honglin Teng, Guoliang Chen

“…All analyses were conducted using R version 4.2.1.ResultsFrom 1990 to 2021, global MM prevalence, incidence, mortality, and DALYs more than doubled, particularly among males. …”
Get full text

Association between the Taq1A polymorphism and problematic media use in preadolescent children by Jennifer A. Emond, Jennifer A. Emond, Timothy J. Renier, Dabin Yeum, Delaina D. Carlson, Grace A. Ballarino, Diane Gilbert-Diamond, Diane Gilbert-Diamond, Diane Gilbert-Diamond

“…Specifically, geometric mean PMU scores were 8.6% greater for each additional copy of the Taq1A1 allele (p = 0.030; R2 = 5.2%). No other polymorphisms were statistically associated with PMU at the p < 0.05 level.ConclusionThese preliminary findings suggest that a genetic predisposition to reduced dopamine sensitivity as indicated by the Taq1A polymorphism may relate to PMU in early adolescence. …”
Get full text

Non-pharmacological interventions for primary hypertension: a systematic review and network meta-analysis protocol by Tao Xu, Fan-rong Liang, Qifu Li, Taipin Guo, Ziwen Chen, Yun-Jie Shu, Xueli Zhou

“…Additionally, prehypertension affects 25%–50% of adults, increasing the risk of cardiovascular complications. …”
Get full text

Impact of Obesity on Clinicopathologic Characteristics and Disease Prognosis in Pre- and Postmenopausal Breast Cancer Patients: A Retrospective Institutional Study by Nehad M. Ayoub, Rami J. Yaghan, Nour M. Abdo, Ismail I. Matalka, Laila M. Akhu-Zaheya, Alia H. Al-Mohtaseb

Get full text

Additive interaction of conjoint tobacco smoking and heavy drinking on hypertension prevalence in rural Uganda: a community-based cross-sectional study by Paineto Masengere, Nynke Halbesma, Rawlance Ndejjo, Bonny Enock Balugaba, Rhoda K. Wanyenze, Fred Nuwaha, Hilde Bastiaens, Geofrey Musinguzi

“…All analyses were performed via R programming software version 4.2.3. Results HBP was prevalent in 23% of the participants. …”
Get full text