Electroacupuncture attenuates ferroptosis by promoting Nrf2 nuclear translocation and activating Nrf2/SLC7A11/GPX4 pathway in ischemic stroke by Xi-chen Yang, Ya-ju Jin, Rong Ning, Qiu-yue Mao, Peng-yue Zhang, Li Zhou, Cheng-cai Zhang, Yi-chen Peng, Na Chen

“…Methods The ischemic stroke model was established by middle cerebral artery occlusion/reperfusion (MCAO/R) in adult rats. These rats have been randomly divided into the EA + MCAO/R group, the MCAO/R group, the EA + MCAO/R + Brusatol group (the inhibitor of Nrf2), and the EA + MCAO/R + DMSO group, and the Sham group. …”
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Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy by Gao Y, Li L, Zhao F, Cheng Y, Jin M, Xue FS

“…Ying Gao,1 Lu Li,1 Fang Zhao,1 Yi Cheng,1 Mu Jin,2 Fu-Shan Xue1,3 1Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republic of China; 3Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaCorrespondence: Mu Jin, Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 An-Zhen Road, Chao-Yang District, Beijing, 100029, People’s Republic of China, Tel +86-13366600987, Email jinmu0119@hotmail.com Fu-Shan Xue, Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong-An Road, Xi-Cheng District, Beijing, 100050, People’s Republic of China, Tel +86-13911177655, Fax +86-591-88217841, Email xuefushan@aliyun.com; xuefushan@mail.ccmu.edu.cnPurpose: This study aimed to assess the protective effect of a clinical dose esketamine on cerebral ischemia/reperfusion (I/R) injury and to reveal the potential mechanisms associated with microglial polarization and autophagy.Methods: Experimental cerebral ischemia was induced by middle cerebral artery occlusion (MCAO) in adult rats and simulated by oxygen-glucose deprivation (OGD) in BV-2 microglial cells. …”
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Profile of Endothelin-1, Nitric Oxide, and Prostacyclin Levels in Pulmonary Arterial Hypertension Related to Uncorrected Atrial Septal Defect: Results from a Single Center Study in... by Lucia Kris Dinarti, Anggoro Budi Hartopo, Dyah Wulan Anggrahini, Ahmad Hamim Sadewa, Budi Yuli Setianto, Abdus Samik Wahab

“…The study design was cross-sectional. The subjects were adult uncorrected secundum ASD with PAH. Pulmonary artery pressure was measured with right heart catheterization. …”
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Peripheral blood miRNAs are associated with airflow below threshold in children with asthma by Anshul Tiwari, Brian D. Hobbs, Rinku Sharma, Jiang Li, Alvin T. Kho, Sami Amr, Juan C. Celedón, Scott T. Weiss, Craig P. Hersh, Kelan G. Tantisira, Michael J. McGeachie

“…Differentially expressed (DE) miRNAs were identified using DESeq2 in R, adjusting for covariates and applying a 10% false discovery rate (FDR). …”
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Prognostic Significance of Serum Proangiogenic Molecules in Patients with De Novo Non-Hodgkin Lymphomas by Pairaya Rujirojindakul, Arnuparp Lekhakula

“…Serum VEGF and bFGF concentrations were measured from 79 adult patients with newly diagnosed stage 2–4 non-Hodgkin lymphomas by quantitative sandwich enzyme immunoassay. …”
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Internet use and e-health literacy among tuberculosis patients in the Directly Observed Therapy Centre, Lagos State, Nigeria by Olalekan Moses Olayemi, Timothy Shola Abolarinwa

“…The study population comprised registered adult tuberculosis patients on active treatment and assessing healthcare in the designated Directly Observed Therapy Centre. …”
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Eight Fungal Species Associated with Ambrosia Beetles in Korea by Mi Jin Jeon, Sangwook Park, Jong Chul Jeong, Jongok Lim, Youngeun Han, Won-Jae Chi, Soonok Kim

“…Ambrosia fungi are well-known for their symbiotic interactions with ambrosia beetles, acting as a sole food source of larvae and adult beetles. As a first step to reveal these interactions, extensive survey on the fungal symbionts of ambrosia beetles dwelling in Korea. …”
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A Prospective Study of Tuberculosis Drug Susceptibility in Sabah, Malaysia, and an Algorithm for Management of Isoniazid Resistance by Muhammad Redzwan S. Rashid Ali, Uma Parameswaran, Timothy William, Elspeth Bird, Christopher S. Wilkes, Wai Khew Lee, Tsin Wen Yeo, Nicholas M. Anstey, Anna P. Ralph

“…Methods. Prospective study of adult outpatients with smear-positive pulmonary tuberculosis (PTB) in Sabah, Malaysia. …”
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The relationship between stress, social support, and quality of life among spouses of patients at the end-of-life stage in Thailand: A correlational study by Rathapon Thawonphat, Tiraporn Junda, Bualuang Sumdaengrit

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Intracardiac Echocardiography as a Guide for Transcatheter Closure of Patent Ductus Arteriosus by Hironaga Yoshimoto, Maeda Yasuto, Tadashi Inoue, Yoshiyuki Kagiyama, Yozo Teramachi, Ryuta Takase, Yusuke Koteda, Yoshihiro Fukumoto, Motofumi Iemura, Kenji Suda

“…In phase 1, we found great correlation and agreement between ICE and AoG/CCT in PA-D (r = 0.985, bias −0.077 to 0.224), but moderate to poor correlation and agreement in length (r = 0.653, bias −0.491 to 3.065) and Ao-D (r = 0.704, bias 0.738 to 4.732), respectively. …”
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Predicting Outcomes for Interhospital Transferred Patients of Emergency General Surgery by Brandon Cave, Daniel Najafali, William Gilliam, Jackson F. Barr, Christian Cain, Chris Yum, Jamie Palmer, Safura Tanveer, Emily Esposito, Quincy K. Tran

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Isopods in the Bioremediation of Invasive Seaweeds? First Experience with the Seaweed <i>Rugulopteryx okamurae</i> Mass Dumped on Beaches by Daniel Patón, José Carlos García-Gómez

“…Future work should explore what percentage of <i>R. okamurae</i> prevents diterpene mortality of isopods and other invertebrates. …”
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Resistance mechanisms involved in complex immunity of wheat against rust diseases by E. S. Skolotneva, E. A. Salina

“…The involvement of some wheat R-genes in pre-haustorial resistance to leaf rust has been discovered recently: Lr1, Lr3a, Lr9, LrB, Lr19, Lr21, Lr38. …”
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Predictors of massive transfusion protocols activation in patients with trauma in Korea: a systematic review by Dongmin Seo, Inhae Heo, Juhong Park, Junsik Kwon, Hye-min Sohn, Kyoungwon Jung

“…All studies conducted in Korea that utilized predictors of MTPs activation in adult patients with trauma were included. Results Ten articles were eligible for analysis, and the predictors were assessed. …”
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Trajectories of Objectively Measured Physical Activity among Secondary Students in Canada in the Context of a Province-Wide Physical Education Policy: A Longitudinal Analysis by Erin Hobin, Jannice So, Laura Rosella, Melisa Comte, Steve Manske, Jonathan McGavock

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Development and validation of the Women Autonomy Scale for measuring psychosocial freedom from conventional gender roles by Waqar Husain, Farrukh Ijaz, Muhammad Ahmad Husain, Achraf Ammar, Khaled Trabelsi, Haitham Jahrami

“…Methods The development and validation of the WAS involved four phases with a total of 2,252 adult women from Rawalpindi and Islamabad, Pakistan. …”
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Morphological and Molecular Descriptions of Macracanthorhynchus ingens (Acanthocephala: Oligacanthorhynchidae) Collected from Hedgehogs in Iran by Mohsen Najjari, Amir Tavakoli Kareshk, Mohammad Darvishi, Gholamreza Barzegar, Majid Dusti, Mohammad Hasan Namaei, Ebrahim Shafaie, Rahmat Solgi

“…At first, infection with M. ingens was diagnosed based on morphologic features of the adults such as body length, proboscis, and hooks. …”
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Design of a Reconfigurable Robotic System for Flexoextension Fitted to Hand Fingers Size by J. Felipe Aguilar-Pereyra, Eduardo Castillo-Castaneda

“…The reconfiguration of mechanisms covers about 95% of hand sizes of a group of Mexican adult population. Maximum trajectory tracking error is less than 3% in full range of movement and it can be compensated by the additional rotation of finger joints without injury to the user.…”
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Mitochondrial Cytochrome c Oxidase Subunit 1 Sequence Variation in Prostate Cancer by Takara A. Scott, Rebecca S. Arnold, John A. Petros

“…Mitochondrial DNA (mtDNA) mutations have been described in every adult neoplasm including prostate cancer. There are marked racial differences in mutations within the cytochrome c oxidase subunit 1 (COI) gene in individuals with prostate cancer (PCa). …”
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Prediction of Corpse Model Drifting Trajectories in Pearl River Front Channel Based on Delft3D Model by CHENG Xiangju, CHEN Zehai, LI Bin, LI Xu, BI Jinjin, WANG Longwei

“…In a case study, the simulated results for an adult female corpse have an error of approximately 300 m. …”
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