CDR-Detector: a chronic disease risk prediction model combining pre-training with deep reinforcement learning by Shaofu Lin, Shiwei Zhou, Han Jiao, Mengzhen Wang, Haokang Yan, Peng Dou, Jianhui Chen

“…Aiming at this challenge, this study combines EHR based pre-training and deep reinforcement learning to develop a novel chronic disease risk prediction model called CDR-Detector. The model adopts the Q-learning architecture with a custom reward function. …”
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Small-scale land use effects on plant communities in Mediterranean urban ecosystems by Vincenzo Baldi, Alessandro Bellino, Daniela Baldantoni

“…For the structural biodiversity, taxa were identified at the species level, estimating their abundance through several measures (number, dry mass, Braun-Blanquet cover), whereas functional traits (biological form, chorological type, Ellenberg indices) were adopted in evaluating vegetation functional diversity. …”
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Mechanism of stable lithium plating and stripping in a metal-interlayer-inserted anode-less solid-state lithium metal battery by Dong-Su Ko, Sewon Kim, Sangjun Lee, Gabin Yoon, Daeho Kim, ChaeHo Shin, Dongmin Kim, Jaewoo Lee, Soohwan Sul, Dong-Jin Yun, Changhoon Jung

“…Through multiple operando and post-mortem analyses of the Li deposition behavior in the morphology, chemistry and microstructure, a close correlation is found between the Li-metal alloying process with the microstructural evolution and electrochemical performance when Ag, Au, Zn, and Cu interlayers were adopted on the garnet-type solid electrolyte Li6.5La3Zr1.5Ta0.5O12. …”
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Evaluating knowledge gains from structured sexual and reproductive health education among in-school adolescents in Southeast Nigeria by Chibuike Agu, Chinyere Ojiugo Mbachu, Ifunanya Clara Agu, Godstime Eigbiremolen, Ugenyi Iloabachie, Ozioma Nwankpa, Obinna Onwujekwe

“…Conclusions Efforts to adopt and scale up SRH interventions should prioritize equal and full participation across all adolescent groups, especially girls, junior students, working adolescents, and urban residents.…”
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Optimizing Polar Air Traffic: Strategies for Mitigating the Effects of Space Weather‐Induced Communication Failures Poleward of 82°N by Dabin Xue, Zhizhao Liu, Donghe Zhang, Cheng‐Lung Wu, Jian Yang

“…Simulation results show that the economic losses associated with these polar flights can range from €0.03 million to €1.32 million, depending on both the duration of communication failures and the adopted air traffic management strategies. We believe that this study can shed light on the effects of space weather‐induced communication failures on polar flight operations and provide guidance for mitigating these effects in the aviation industry.…”
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Art of TIL immunotherapy: SITC’s perspective on demystifying a complex treatment by Robert Brown, Marco Donia, Simon Turcotte, George Coukos, John Mullinax, Brian Gastman, James C Yang, Michael T Lotze, John B A G Haanen, Inge Marie Svane, Stephanie L Goff, Vernon K Sondak, Maartje W Rohaan, Michal Besser, Benjamin Creelan

“…The highly multidisciplinary clinical expertise and coordination required to successfully and safely deliver TIL to patients began within the National Cancer Institute Surgery Branch and have been subsequently adopted worldwide. The general steps, most of which require hospital inpatient resources, include a surgical procedure to harvest sufficient tumor for TIL manufacturing, admission for non-myeloablative lymphodepleting chemotherapy followed by TIL, and intravenous interleukin-2 (IL-2, aldesleukin). …”
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A synthetic biological secondary metabolite, Lycogenâ¢, produced and extracted from Rhodobacter sphaeroides WL-APD911 in an optimizatioal scale-up strategy by Cheng-Chin Wang, Shi-Ying Huang, Shu-Hung Huang, Zhi-Hong Wen, Jyun-Ying Huang, Wen-Sheng Liu, Hui-Min David Wang

“…Further, the batch fermentation is carried out in both 5 L and 20 L fermentors to study the scale-up process factors to be adopted. At a 20 L fermentor, Lycogen⢠yields under the optimal culture condition are over 2 times than in the shake flask. …”
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Proteomic analysis reveals the roles of silicon in mitigating glyphosate-induced toxicity in Brassica napus L. by Probir Kumar Mittra, Md Atikur Rahman, Swapan Kumar Roy, Soo-Jeong Kwon, Abhik Mojumdar, Sung Ho Yun, Kun Cho, Seong-Woo Cho, Meiliang Zhou, Tomoyuki Katsube-Tanaka, Sun-Hee Woo

“…Abstract Glyphosate (Gly) is a widely used herbicide for weed control in agriculture, but it can also adversely affect crops by impairing growth, reducing yield, and disrupting nutrient uptake, while inducing toxicity. Therefore, adopting integrated eco-friendly approaches and understanding the mechanisms of glyphosate tolerance in plants is crucial, as these areas remain underexplored. …”
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3D printing driving innovations in extreme low-temperature energy storage by Shutong Qin, Jiao Dai, Haoran Tian, Hanyuan Zhang, Jingru Huang, Tianqi Guan, Weilin Xu, Jun Wan

“…Unlike studies focused on single materials or technologies, this review adopts an interdisciplinary and systematic framework, linking material properties with 3D printing optimisation. …”
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IL-33 Aggravates DSS-Induced Acute Colitis in Mouse Colon Lamina Propria by Enhancing Th2 Cell Responses by Junfeng Zhu, Fangli Yang, Lixuan Sang, Jingbo Zhai, Xiaoqing Zhang, Dan Yue, Shengjun Li, Yan Li, Changlong Lu, Xun Sun

“…Our results suggested that IL-33 stimulated CD4+T cells and caused the cell to adopt a Th2-type response but at the same time suppressed Th17 and Th1 cell responses. …”
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Modification of Business Strategy Through The Application of Circular Economy in Coffee Shop Business Units in Pontianak City: Case Study of Four Coffee Shops by Mahardika Agung Madepo, Lina Budiarti, Faaiza Soraya Khalida

“…These conditions require the development of alternative strategies, especially by adopting environmentally based strategies. Purpose: This study aims to analyze the choice of modern coffee shop strategy, to analiyze strategy development by adding the circular economy concept to it, and to analyze the sustainability of the circular economy-based strategy that will be implemented. …”
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Elucidation of the Inhibitory Effect of Phytochemicals with Kir6.2 Wild-Type and Mutant Models Associated in Type-1 Diabetes through Molecular Docking Approach by Manaswini Jagadeb, V Badireenath Konkimalla, Surya Narayan Rath, Rohit Pritam Das

“…The current work is intended to investigate the affinity of four phytochemicals namely, curcumin (Curcuma longa), genistein (Genista tinctoria), piperine (Piper nigrum), and pterostilbene (Vitis vinifera) in a normal as well as in a mutant kir6.2 model by adopting a molecular docking methodology. The phytochemicals were docked in both wild and mutated kir6.2 models in two rounds: blind docking followed by ATP-binding pocket-specific docking. …”
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Impact of High Glucose on Bone Collagenous Matrix Composition, Structure, and Organization: An Integrative Analysis Using an Ex Vivo Model by Rita Araújo, Ricardo N. M. J. Páscoa, Raquel Bernardino, Pedro S. Gomes

“…A comprehensive approach integrating histological evaluation, histomorphometry, ATR-FTIR spectroscopy, and proteomics was adopted to unravel structural, biochemical, and molecular changes in the ECM. …”
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Engagement factors affect academic success through study approaches among physical education and sport university students: a mediation analysis by Amayra Tannoubi, Amayra Tannoubi, Tore Bonsaksen, Tore Bonsaksen, Gry Mørk, Farruh Ahmedov, Edi Setiawan, Fairouz Azaiez

“…IntroductionUniversity students should engage with the study and ensure they adopt productive study approaches, but the nature of relationships between engagement and study approaches are under-researched. …”
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Optimization of Extraction Process of Methyl Eugenol and Asarinin in Asarum with Deep Eutectic Solvent Based on the Response Surface Methodology by Huiwei Bao, Yang Xu, Yuejie Wang, Tao Zhang, Enpeng Wang, Xin Huang, Changbao Chen, Fangxin Liu

“…Single-factor experiments were adopted to investigate the influence of molar ratio, liquid-to-solid ratio, eddy time, ultrasonic time, and temperature of the deep eutectic solvent on the extraction rate of methyl eugenol and asarinin. …”
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Dog Bites and Rabies in the Eastern Region of Ghana in 2013–2015: A Call for a One-Health Approach by Boakye-Yiadom Adomako, Frank Baiden, Samuel Sackey, Donne Kofi Ameme, Fred Wurapa, Kofi Mensah Nyarko, Ernest Kenu, Edwin Afari

“…An integrated approach to surveillance based on the One-Health concept needs to be adopted.…”
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Mental health literacy among older adults in Shanghai: a descriptive qualitative study by Rongjing Xu, Mingrui Jing, Aining Zhang, Liqi Zha, Yan Wang, Anni Wang, Jun Tang, Biyun Xia, Shoumei Jia

“…Improving the mental health literacy of older adults can help them recognize mental illness and adopt proactive measures, potentially improving their mental health status and supporting the goal of healthy aging.ObjectiveTo explore mental health literacy among older adults, providing a foundation for future interventions aimed at improving their mental health literacy.MethodsGuided by the new conceptualization framework of mental health literacy developed by Jiang et al. the study involved 20 community-dwelling older adults from four communities in Shanghai who were selected through purposive sampling to participate in semi-structured interviews. …”
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Drastic Improvements in Air Quality in Ecuador during the COVID-19 Outbreak by Rasa Zalakeviciute, Renne Vasquez, Daniel Bayas, Adrian Buenano, Danilo Mejia, Rafael Zegarra, Valeria Diaz, Brian Lamb

“…While the population in Quito adhered to the quarantine measures immediately, in the port city of Guayaquil, quarantine measures were slow to be adopted and, thus, the effect on air quality in Guayaquil occurred more slowly. …”
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Determination of Tributyltin in Seafood Based on Magnetic Molecularly Imprinted Polymers Coupled with High-Performance Liquid Chromatography-Inductively Coupled Plasma Mass Spectro... by Hua Yang, Huien Zhang, Xiao Yan Zhu, Shi Da Chen, Lijun Liu, Daodong Pan

“…In this study, Fe3O4 was adopted as a carrier for surface molecular imprinting with two-stage polymerization. …”
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Investigation of Theoretical Models, Pumping-Recharge Well Arrangements and System Performance of Abandoned Mine Water Source Heat Pump by Zhiqiang Zhang, Wenchao Zu, Wenke Zhang, Kexun Wang, Xueqing Ma, Ping Cui

“…In this article, the feasibility of applying a water resource heating system in abandoned mines is explored, adopting mine water in the extraction zone as the research object. …”
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