Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1 by Simone Maria Kluth, Teja Falk Radke, Gesine Kögler

“…In contrast to stromal cells from the adult bone marrow (BM) or adipose tissue, cord blood (CB) multipotent stromal cells (MSC) are biologically younger. …”
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Type 2 Diabetes Mellitus and its Relationship with Obesity by Lina Neri Espinosa Pire, Iruma Alfonso González, Michelle Ariana Calvache Vargas, Holger Alexander Lozano Ati

“…The insulin resistance observed in diabetic patients with obesity is caused by inflammation and the presence of immune cells in adipose tissue. In the latter, substances such as leptin and resistin are secreted that increase insulin resistance. …”
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A Molecular and Whole Body Insight of the Mechanisms Surrounding Glucose Disposal and Insulin Resistance with Hypoxic Treatment in Skeletal Muscle by R. W. A. Mackenzie, P. Watt

“…Indeed, hypoxia has been widely implicated in the development of insulin resistance either via the direct action on insulin receptor substrate (IRS) and protein kinase B (PKB/Akt) or indirectly through adipose tissue expansion and systemic inflammation. Yet hypoxia is also known to encourage glucose transport using insulin-dependent mechanisms, largely reliant on the metabolic master switch, 5′ AMP-activated protein kinase (AMPK). …”
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An Immunomodulatory Device Improves Insulin Resistance in Obese Porcine Model of Metabolic Syndrome by Angela J. Westover, Kimberly A. Johnston, Deborah A. Buffington, H. David Humes

“…This inflammation centers around circulating monocytes which form proinflammatory adipose tissue macrophages (ATM). Specific approaches targeting monocytes/ATM may improve insulin resistance without the adverse side effects of generalized immunosuppression. …”
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The immunological perspective of major depressive disorder: unveiling the interactions between central and peripheral immune mechanisms by Wenli Jiao, Jiayi Lin, Yanfang Deng, Yelin Ji, Chuoyi Liang, Sijia Wei, Xi Jing, Fengxia Yan

“…Peripherally, systemic inflammation, gut immune dysregulation, and immune dysfunction in organs including gut, liver, spleen and adipose tissue influence brain function through neural and molecular pathways. …”
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Proteomic profiling of iPSC and tissue-derived MSC secretomes reveal a global signature of inflammatory licensing by Margeaux Hodgson-Garms, Matthew J. Moore, Mikaël M. Martino, Kilian Kelly, Jessica E. Frith

“…This study analysed the secretomes of bone-marrow (BM.MSCs), umbilical-cord (UC.MSCs), adipose-tissue (AT.MSCs) and clinical/commercial-grade induced pluripotent stem cell-derived MSCs (iMSCs), under resting and inflammatory licenced conditions. iMSCs recapitulated the inflammatory licensing process, validating their comparability to tissue-derived MSCs. …”
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An Assessment of the Intestinal Lumen as a Site for Intervention in Reducing Body Burdens of Organochlorine Compounds by Ronald J. Jandacek, Stephen J. Genuis

“…Once in the body, stored OCs can mobilize from adipose tissue storage sites and, along with circulating OCs, are delivered into the small intestine via hepatic processing and biliary transport. …”
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The role of immunity in insulin resistance in patients with polycystic ovary syndrome by Qixuan Zhang, Zhe Yang, Xiangyang Ou, Mengying Zhang, Xiangyu Qin, Gengxiang Wu

“…Polycystic ovary syndrome (PCOS) is a prevalent disorder of the endocrine system with significant clinical implications, often leading to health complications related to adipose tissue accumulation, including obesity, insulin resistance (IR), metabolic syndrome, and type 2 diabetes mellitus. …”
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Current Perspectives in Mesenchymal Stem Cell Therapies for Osteoarthritis by Baldur Kristjánsson, Sittisak Honsawek

“…Mesenchymal stem cells (MSCs) are multipotent progenitor cells found in various tissues, most commonly bone marrow and adipose tissue. MSCs are capable of differentiating into osteocytes, adipocytes, and chondrocytes. …”
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Angiomyolipoma of the Thoracic Wall: An Extremely Rare Diagnostic Challenge by Georgios Gemenetzis, Eleni Kostidou, Kalliroi Goula, Vassilios Smyrniotis, Nikolaos Arkadopoulos

“…Histologically, the lesion consisted of convoluted thick-walled blood vessels without an elastic layer, interlacing fascicles of smooth muscle, and mature adipose tissue, features consistent with an angiomyolipoma. …”
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Saliva and Blood Asprosin Hormone Concentration Associated with Obesity by Kader Ugur, Suleyman Aydin

“…Asprosin, a new adipokine, may be a novel indicator of adipose tissue mass. Therefore, we anticipate that antiasprosin preparations may be an alternative in the treatment of obesity in the future.…”
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Werner Syndrome Caused by Homozygous Frameshift Variant c.1578del in WRN by Jovita Patricija Druta, Gunda Petraitytė, Aušra Sasnauskienė, Eglė Preikšaitienė

“…There was a progression of contractures of the plantar tendons, as well as the atrophy of the subcutaneous adipose tissue of the extremities. The patient was initially diagnosed with secondary small fiber sensory polyneuropathy and myotonia, but further genetic testing revealed the homozygous pathogenic variant c.1578del in the WRN gene associated with Werner syndrome. …”
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Obesity Hypertension: The Regulatory Role of Leptin by Shilpa Kshatriya, Kan Liu, Ali Salah, Tamas Szombathy, Ronald H. Freeman, Garry P. Reams, Robert M. Spear, Daniel Villarreal

“…Leptin is a 16-kDa-peptide hormone that is primarily synthesized and secreted by adipose tissue. One of the major actions of this hormone is the control of energy balance by binding to receptors in the hypothalamus, leading to reduction in food intake and elevation in temperature and energy expenditure. …”
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Analysis of the Pro- and Anti-Inflammatory Cytokines Secreted by Adult Stem Cells during Differentiation by Amy L. Strong, Jeffrey M. Gimble, Bruce A. Bunnell

“…The abundance of ASCs in adipose tissue and easy accessibility with relatively little donor site morbidity make them attractive candidate cells for tissue engineering and regenerative medicine. …”
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Role of Adipokines and Other Inflammatory Mediators in Gestational Diabetes Mellitus and Previous Gestational Diabetes Mellitus by Nikolaos Vrachnis, Panagiotis Belitsos, Stavros Sifakis, Konstantinos Dafopoulos, Charalambos Siristatidis, Kalliopi I. Pappa, Zoe Iliodromiti

“…Research has recently focused on a group of substances produced mainly by adipose tissue called adipokines, this group including, among others, adiponectin, leptin, Retinol-Binding Protein-4 (RBP-4), and resistin. …”
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Leptin, Adiponectin, and Obesity among Caucasian and Asian Women by Shannon M. Conroy, Weiwen Chai, Unhee Lim, Adrian A. Franke, Robert V. Cooney, Gertraud Maskarinec

“…Ethnic differences in adipose tissue distribution may contribute to different chronic disease risks across ethnic groups, and adipokines may mediate the risk. …”
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Effects of breaking up prolonged sitting via exercise snacks intervention on the body composition and plasma metabolomics of sedentary obese adults: a randomized controlled trial by Jianming Zhou, Xiaoning Gao, Dandan Zhang, Chuanwu Jiang, Wenbing Yu

“…Systemic and regional fat mass, epicardial adipose tissue (EAT), abdominal visceral (AVFA) and subcutaneous (ASFA) fat area and plasma metabolomics data were measured before and after intervention. …”
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Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases: Role of Adipokines by Manfredi Tesauro, Maria Paola Canale, Giuseppe Rodia, Nicola Di Daniele, Davide Lauro, Angelo Scuteri, Carmine Cardillo

“…Secretory products of adipose tissue also deeply and negatively influence endothelial function. …”
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Metabolic Risk Susceptibility in Men Is Partially Related to Adiponectin/Leptin Ratio by Gloria Lena Vega, Scott M. Grundy

“…Adipokine levels may reflect adipose tissue triglyceride storage capacity and insulin sensitivity. …”
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Allogeneic Mesenchymal Stem Cell Treatment Induces Specific Alloantibodies in Horses by Sean D. Owens, Amir Kol, Naomi J. Walker, Dori L. Borjesson

“…Bone marrow (BM) or adipose tissue derived MSCs (ad-MSCs) were administered via intravenous, intra-arterial, intratendon, or intraocular routes. …”
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