Circadian Clocks and the Interaction between Stress Axis and Adipose Function by Isa Kolbe, Rebecca Dumbell, Henrik Oster

“…In this review, we summarize our current understanding of adrenal and adipose tissue rhythms and clocks and how they might interact to regulate energy homoeostasis and stress responses under physiological conditions. …”
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Exercise-Induced Irisin, the Fat Browning Myokine, as a Potential Anticancer Agent by George-Emmanuel Maalouf, Diala El Khoury

“…Irisin is a recently discovered myokine that plays an important role in fat metabolism through the browning of white adipose tissue. This myokine is usually secreted after exercise by improving energy balance and has shown great potential as a possible treatment for some metabolic diseases such as obesity, insulin resistance, and inflammation. …”
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Debilitating Manifestation of a Disease with Multiple Names: A Severe Case of Sclerosing Mesenteritis by Valeriia Klymenko, Reba Varughese, Katherine A Woolley, Joseph M Wetherell, Haritha Mopuru, Edward Mensah, Imran Siddiqui

“…Sclerosing mesenteritis (SM) is a rare inflammatory condition with unknown etiology that affects the mesenteric adipose tissue. We present a case of a 49-year-old male with severe abdominal pain who underwent abdominal biopsy confirming the presence of adipose inflammation and necrosis. …”
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Congenital Infiltrating Lipomatosis of the Face: A Case Report by Asha Mahadevappa, Vanisri H. Raghavan, Sunila Ravishankar, Gubbanna V. Manjunath

“…It is characterized by (1) no encapsulation, (2) diffuse infiltration of mature adipose tissue over normal muscle fiber and surrounding structures of face, (3) osseous hyperplasia of subjacent bone, and (4) a high recurrence rate. …”
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Contribution of Neuroinflammation to the Pathogenesis of Cancer Cachexia by Alessio Molfino, Gianfranco Gioia, Filippo Rossi Fanelli, Alessandro Laviano

“…Robust data indicate that, during cancer, functional modifications within brain areas regulating energy homeostasis contribute to the onset of anorexia, reduced food intake, and increased catabolism of muscle mass and adipose tissue. In particular, functional changes are associated with increased hypothalamic concentration of proinflammatory cytokines, which suggests that neuroinflammation may represent the adaptive response of the brain to peripheral challenges, including tumor growth. …”
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Cardiac Hypertrophy and Fibrosis in the Metabolic Syndrome: A Role for Aldosterone and the Mineralocorticoid Receptor by Eric E. Essick, Flora Sam

“…These studies illustrate a complex cross-talk between adipose tissue, the heart, and the adrenal cortex. Furthermore, we discuss findings from our laboratory that suggest that cardiac hypertrophy and fibrosis in the metabolic syndrome may involve cross-talk between aldosterone and adipokines (such as adiponectin).…”
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Giant Lipoma Presents from the Buccal Vestibule by Yuki Sakamoto, Gohei Oyama

“…A lipoma is a benign tumor, where the parenchyma is composed of adipose tissue. Lipomas comprise 0.1%–5% of all benign tumors in the oral cavity. …”
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Daily feeding frequency impacts muscle characteristics and fat deposition in finishing pigs associated with alterations in microbiota composition and bile acid profile by Luga Hu, Huayu Tang, Zhaoxi Xie, Hongyu Yi, Lunjie Feng, Pan Zhou, Yong Zhang, Jingbo Liu, Xiang Ao, Jianchuan Zhou, Honglin Yan

“…The muscle fiber characteristics, lipid metabolism in adipose tissue, and cecal microbiota and bile acid composition were determined.ResultsThe present study revealed that pigs fed four meals exhibited a lower feed-to-gain ratio, abdominal fat weight, and average backfat thickness (p < 0.05), as well as a higher loin eye area (p = 0.09) and myofiber diameter in the longissimus muscle than their counterparts. …”
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The combined effect of metformin and mirabegron on diet‐induced obesity by Xin‐Yuan Zhao, Ying Liu, Xuan Zhang, Ben‐Chi Zhao, George Burley, Zhi‐Can Yang, Yi Luo, An‐Qi Li, Ruo‐Xin Zhang, Zhi‐Ying Liu, Yan‐Chuan Shi, Qiao‐Ping Wang

“…These benefits of Met/Mir were associated with increased EE, activated brown adipose tissue thermogenesis, and white adipose tissue browning. …”
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Signaling Pathway Puts the Break on Fat Cell Formation by Ormond A. MacDougald

“…Unfortunately, excess fat or adipose tissue is associated with a wide array of health problems, including increased incidence of type II diabetes, cardiovascular disease, hypertension, sleep apnea, and skeletomuscular problems [4,5,6]. …”
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Adipose-Derived Mesenchymal Stem Cells in the Use of Cartilage Tissue Engineering: The Need for a Rapid Isolation Procedure by Sam L. Francis, Serena Duchi, Carmine Onofrillo, Claudia Di Bella, Peter F. M. Choong

“…MSCs can be obtained from many different tissue sources. Among these, adipose tissue can provide an abundant source of adipose-derived mesenchymal stem cells (ADMSCs). …”
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Drosophila melanogaster as an alternative animal model in fat metabolism studies by Dilan de Silva, Mangala Gunatilake

“…Fat storage in Drosophila occurs in the form of lipid droplets carrying cholesterol and triacylglycerol which are accumulated primarily in the fat body – the analogous Drosophila organ to mammalian adipose tissue. Moreover, the Drosophila fat body has showcased its role in storage and metabolic regulation, akin to the function of the liver in mammals. …”
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Swim Training Attenuates Inflammation and Improves Insulin Sensitivity in Mice Fed with a High-Fat Diet by Guangzeng Zhang, Pengfei Yu, Xiaomeng Liu

“…Moreover, swim training considerably decreased serum LPS content and downregulates epididymis white adipose tissue (eWAT) expression of the inflammatory mediator Tnf-α, Il-6, and Mcp-1. …”
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NOD1: a metabolic modulator by Ruobing Tang, Chunguang Xie, Chunguang Xie, Chunguang Xie, Xiyu Zhang, Xiyu Zhang, Xiyu Zhang

“…Furthermore, NOD1 serves as a metabolic mediator by influencing the metabolism of various tissues, including adipose tissue, liver, cardiovascular tissue, pancreatic β cells, adrenal glands, and bones through diverse mechanisms. …”
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A Neonate with CLOVES Syndrome by Dilek Sarici, Mustafa Ali Akin, Selim Kurtoglu, Filiz Tubas, Serdar Umit Sarici

“…Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (CLOVE) syndrome is a recently delineated disorder that comprises vascular malformations (typically truncal), dysregulated adipose tissue, scoliosis, enlarged bony structures (typically of the legs) without progression, or distorting bony overgrowth. …”
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Cancer Cachexia: Mechanisms and Clinical Implications by Claire L. Donohoe, Aoife M. Ryan, John V. Reynolds

“…Cachexia is a multifactorial process of skeletal muscle and adipose tissue atrophy resulting in progressive weight loss. …”
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Exposure to triphenyl phosphate during pregnancy: The role of gut-bile acids-liver axis on lipid metabolism in male offspring by Juntong Lin, Fuhui Yan, Longhui Liu, Ganzhong Liao, Yilei Xu, Qian Liu, Miaoliang Wu, Honghui Guo, Bai Zhi, Lianxian Guo, Xiaoshan Liu

“…The results showed that gestational TPhP exposure would induce hyperlipidemia in male offspring, it dose-dependently increased the weight of body and liver, levels of serum lipid, and enlarged lipid droplets in white adipose tissue. The expression of lipid metabolism-related genes was significantly changed in the liver and adipose tissue. …”
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Exercise-induced anxiety impairs local and systemic inflammatory response and glucose metabolism in C57BL/6J mice by I. Gálvez, M.C. Navarro, S. Torres-Piles, L. Martín-Cordero, M.D. Hinchado, E. Ortega

“…Phagocytic/microbicide activity, the expression of M1/M2 phenotype markers (CD11c, iNOS, CD206, ARG-1) and cytokines of the inflammatory response (MCP-1, IL-8, IL-6, TNF-α, TGF-β, IL-10) of peritoneal macrophages were determined via flow cytometry. Adipose tissue macrophage infiltration was studied through fluorescence immunohistochemistry. …”
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Adipocyte Atrophy Mimicking Signet Ring Cell Carcinoma of the Gallbladder by Benjamin van Haeringen, Leo Francis, Emily Olive, Daniel James

“…Benign epithelial signet ring cell change is well described in a variety of tissues, but nonepithelial signet ring cell change is a rare morphologic adaptation of adipose tissue principally described in the setting of cachexia. …”
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Perspectives for Clinical Translation of Adipose Stromal/Stem Cells by Mimmi Patrikoski, Bettina Mannerström, Susanna Miettinen

“…Adipose stromal/stem cells (ASCs) are an ideal cell type for regenerative medicine applications, as they can easily be harvested from adipose tissue in large quantities. ASCs have excellent proliferation, differentiation, and immunoregulatory capacities that have been demonstrated in numerous studies. …”
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