THE LEGALITY OF ONLINE TRANSACTIONS IN MOSQUES AN ISLAMIC LAW PERSPECTIVE BASED ON AL-JAZIRI'S AL-FIQH 'ALA AL-MAZAH IB AL-ARBA'AH by Muhd Syahrul Akbar

“…Kata Kunci: Jual Beli Online, Hukum Islam, Masjid   ABSTRACT: Generally, purchase and sale is carried out at a certain place and time, but in today's era purchase and sale transactions are no longer limited by place and time, this is due to technological advances that make purchase and sale activities can be done via the internet or better known as online shopping, so that people can make purchase and sale transactions whenever and wherever, there are even people who make online shopping transactions in mosques. …”
Get full text

The impact of routines on emotional and behavioural difficulties in children and on parental anxiety during COVID-19 by Vera Lees, Rosie Hay, Helen Bould, Helen Bould, Helen Bould, Alex S. F. Kwong, Daniel Major-Smith, Daniel Major-Smith, Daphne Kounali, Rebecca M. Pearson, Rebecca M. Pearson

“…Routine was taken as keeping to the same basic activities such as mealtimes and bedtimes. We also hypothesised that children of ‘keyworker’ parents would have fewer emotional and behavioural symptoms due to having maintained more normal routines. …”
Get full text

Effect of Interference Electric Stimulation at Baliao and Dachangshu Acupoints Combined with Mosapride on Constipation Patients with Diabetes by JIANG Huiyu, ZHOU Wei, MING Xiaohong, LIU Haichao, WU Xiuxiang

“…The clinical effect of the observation group was higher than that of the control group (<italic>P</italic>&lt;0.05). ④ SF-36 score: compared with that before treatment, the quality of life score of two groups after the treatment was increased significantly (<italic>P</italic>&lt;0.05); compared with the control group, the quality of life score in the observation group after the treatment was increased significantly (<italic>P</italic>&lt;0.05).ConclusionInterference electric stimulation at Baliao acupoint and Dachangshu acupoint combined with mosapride can more effectively accelerate gastrointestinal peristalsis, relax anal sphincter and activate pelvic floor muscle, so as to promote defecation and improve defecation function.…”
Get full text

Specifically blocking αvβ8-mediated TGF-β signaling to reverse immunosuppression by modulating macrophage polarization by Cuicui Guo, Hui Sun, Yulei Du, Xiaodong Dai, Yu Pang, Zhen Han, Xinhui Xiong, Shaowei Li, Junhua Zhang, Qingbing Zheng, Xun Gui

“…Integrin αvβ8, a pivotal activator of TGF-β, has been implicated in TGF-β signaling within tumors, as demonstrated by the significant anti-tumor effects of anti-αvβ8 antibodies. …”
Get full text

Effect of Repetitive Transcranial Magnetic Stimulation on Patients with Post-Stroke Cognitive Impairment by Zheyi YU, Weiming ZHANG

“…Before and after treatment, the cognitive function scores of the two groups were compared, the changes of mini-mental state examination (MMSE) and Montreal cognitive function (MoCA) scores were compared, the activities of daily living (ADL) and auditory verbal learning test (AVLT) were observed. …”
Get full text

Treatment of chronic hepatitis C by cepeginterferon alpha-2b in combination to ribavirin by M. V. Mayevskaya, O. O. Znoyko, Ye. A. Klimova, S. L. Maximov, S. N. Kizhlo, N. A. Petrochenkova, F. I. Nagimova, Yu. N. Linkova

“…In open randomized «noninferiority» clinical study of II–III phase 150 previously untreated by interferon adult CHC patients (genotypes 1, 2, 3) were randomized in three medical groups: Algeron 1,5 mkg/kg, Algeron 2,0 mkg/kg and active control group — PegIntron 1,5 mkg/kg. All patients received ribavirin 800-1400 mg/day for 24-48 wks in relation to genotype. …”
Get full text

Utilization of hydrolyzed corncob as a carbohydrate source in diets for red Nile tilapia Oreochromis niloticus by Fauzan, Muhammad Agus Suprayudi, Ichsan Achmad Fauzi, Julie Ekasari

“…The digestibility test results showed that the hydrolyzed corn cob diet obtained a higher digestibility level, digestive enzyme activity, and blood plasma protein than the unhydrolyzed corncob diet (P<0.05). …”
Get full text

Effect of L-Citrulline on Creatine Kinase MM (CK-MM) Isoenzymes in Mice: An In Vivo Study Focusing on Immunohistochemistry Analysis by Dhoni Akbar Ghozali, Annisa Aghnia Rahma, Shafira Nur Hanifa, Muhana Fawwazy Ilyas

“…This study contributes valuable insights into the multifaceted benefits of L-citrulline supplementation for supporting overall muscle health and performance by identifying its protective effects under different mechanisms, including improved blood flow, antioxidant activity, enhanced mitochondrial function, and promotion of muscle protein synthesis.   …”
Get full text

Sistem Informasi Geografis Penyebaran Usaha Mikro Kecil Menengah (UMKM) di Kabupaten Majalengka by Muhammad Darul Husni Santoso, Ikbal Jamaludin, Evi Dewi Sri Mulyani

“…With the construction of this system, information about the location points as well as MSME data in accordance with their business activities can be displayed. The results of this study are in the form of a geographic information system, in which this system can provide information to the Cooperative and MSME Service Offices in Majalengka Regency regarding spatial information on MSME distribution locations that can assist in the management and supervision of business growth based on the location and type of MSME. …”
Get full text

4-Octyl itaconate inhibits synovitis in the mouse model of post-traumatic osteoarthritis and alleviates pain by Yu-Zhen Tang, Wan Chen, Bao-Yun Xu, Gang He, Xiu-Cheng Fan, Kang-Lai Tang

“…Consequently, this treatment alleviated pain in PTOA mice (p < 0.001) and reduced spontaneous activity (p = 0.003). Bioinformatics and network pharmacology analyses indicated that 4-OI may exert its therapeutic effects by inhibiting the differentiation of synovial Th17 cells. …”
Get full text

Distribution of Vibrio parahaemolyticus in pacific white shrimp Litopenaeus vannamei through immersion as a natural infection model by Sukma Sari Anggraeni, Sukenda, Sri Nuryati, Dinamella Wahjuningrum

“…Immune responses, including total hemocytes, phagocytic activity, phenoloxidase, and respiratory burst, demonstrated significantly different results (P<0.05). …”
Get full text

Ginger-Derived Exosome-Like Nanoparticles Loaded With Indocyanine Green Enhances Phototherapy Efficacy for Breast Cancer by Guo Z, Li G, Shen L, Pan J, Dou D, Gong Y, Shi W, Sun Y, Zhang Y, Ma K, Cui C, Li W, Liu Q, Zhu X

“…Moreover, by detecting the expression of CD31, N-cadherin, IL-6, IFN-γ, CD8, p16, p21, and p53 in tumor tissues, we found that GDNPs@ICG substantially reduced angiogenesis, inhibited metastasis, activated the anti-tumor immune response, and promoted cell senescence in breast tumor.Conclusion: Our study demonstrated that the novel bio-nanoplatform GDNPs@ICG enhanced the photo-mediated therapeutic effect in breast tumor. …”
Get full text

Traditional herbal medicine legislative and regulatory framework: a cross-sectional quantitative study and archival review perspectives by Sileshi Dubale, Rashed Edris Usure, Yesuneh Tefera Mekasha, Gemmechu Hasen, Firdos Hafiz, Dereje Kebebe, Sultan Suleman

“…Among regulatory experts, weak performance was identified in the practical implementation of THM regulatory activities, with 70.2% of weak performance observed at the federal level and 41.7% at the regional level. …”
Get full text

Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject ‘cold’ tumors by Laetitia Fend, Eric Quemeneur, Monika Semmrich, Jean-Baptiste Marchand, Matilda Rehn, Nathalie Silvestre, Linda Mårtensson, Johann Foloppe, Ingrid Teige, Björn Frendeus, Petra Holmkvist, Carolin Svensson, Christelle Remy, Patricia Kleinpeter, Jules Deforges, Fred Junghus, Kirstie L Cleary, Mimoza Bodén

“…Here we assess and identify spatially restricted exposure to a novel strongly Treg-depleting, checkpoint-blocking, vectorized αCTLA-4, as a highly efficacious and potentially safe strategy to target CTLA-4.Methods A novel human IgG1 CTLA-4 antibody (4-E03) was identified using function-first screening for monoclonal antibodies (mAbs) and targets associated with superior Treg-depleting activity. A tumor-selective oncolytic vaccinia vector was then engineered to encode this novel, strongly Treg-depleting, checkpoint-blocking, αCTLA-4 antibody or a matching surrogate antibody, and Granulocyte-macrophage colony-stimulating factor (GM-CSF) (VVGM-αCTLA-4).Results The identified 4-E03 antibody showed significantly stronger Treg depletion, but equipotent checkpoint blockade, compared with clinically validated αCTLA-4 ipilimumab against CTLA-4-expressing Treg cells in a humanized mouse model in vivo. …”
Get full text

Significance of supervision sampling in control of communicable respiratory disease simulated by a new model during different stages of the disease by Alphonse Houssou Hounye, Xiaogao Pan, Yuqi Zhao, Cong Cao, Jiaoju Wang, Abidi Mimi Venunye, Li Xiong, Xiangping Chai, Muzhou Hou

“…By integrating different control measures, respiratory-specific modeling, and disease supervision sampling into an expanded SEI (A) R epidemic model, we found that supervision sampling can improve early warning of viral activity levels and superspreading events, and explained the significance of containments in controlling COVID-19 transmission and the rationality of policy by the influence of different containment measures on the transmission rate. …”
Get full text

Massive permafrost rock slide under a warming polythermal glacier deciphered through mechanical modeling (Bliggspitze, Austria) by F. Pfluger, S. Weber, S. Weber, J. Steinhauser, C. Zangerl, C. Fey, J. Fürst, M. Krautblatter

“…The high mineralization measured at springs at a proximal distance to the failure volume indicates active-layer thaw. The inversion of electrical resistivity tomography revealed thaw that reached several decameters in depth in the collapsed rock mass 2 years after failure. …”
Get full text

Reliability of non-invasive imaging methods in the evaluation of pancreatic parenchyma changes in tumors of the pancreaticoduodenal zone by M.M. Veligotskyy, S.E. Arutyunov, I.I. Yakovtsova, I.V. Ivakhno, O.M. Veligotskyi

“…Ki-67, a marker of proliferative activity, was used to conduct immunohistochemical study. …”
Get full text

Ibuprofen reduces inflammation, necroptosis and protects photoreceptors from light-induced retinal degeneration by Ping-Wu Zhang, Zi-He Wan, Weifeng Li, Abhishek Vats, Kunal Mehta, Laura Fan, Lingli Zhou, Sean Li, Gloria Li, Casey J. Keuthan, Cynthia Berlinicke, Cheng Qian, Noriko Esumi, Elia J Duh, Donald J. Zack

“…Expression of key necroptosis genes, including Ripk3 and Mlkl, were upregulated in LD vehicle-treated mice, but dramatically reduced to near no LD levels in LD IBU-treated mice. Microglia activation and MLKL protein upregulation were observed primarily in photoreceptors 12 h after LD, as assessed by immunohistochemistry. …”
Get full text

Perspectives and Practices of Healthcare Leaders in Supporting Healthcare Worker Well-Being: A Reality Check by Reijmerink IM, van der Laan MJ, Scheele F, Wietasch JKG

“…We argue that it is essential for leaders at all hierarchical levels to assume responsibility actively and collectively for employee well-being, transitioning to a proactive approach in promoting and safeguarding the well-being of HCWs.Plain Language Summary: Healthcare workers play a key part in the healthcare system, so their well-being is very important. …”
Get full text

Genomic and resistome analysis of Salmonella enterica isolates from retail markets in Yichun city, China by Xiaowu Jiang, Abubakar Siddique, Li Chen, Lexin Zhu, Haiyang Zhou, Li Na, Chenghao Jia, Yan Li, Min Yue

Get full text