Immediate modulatory effects of transcutaneous vagus nerve stimulation on patients with Parkinson’s disease: a crossover self-controlled fMRI study by Chengwei Fu, Chengwei Fu, Chengwei Fu, Xiaoyan Hou, Chunye Zheng, Yue Zhang, Zhijie Gao, Zhijie Gao, Zhaoxian Yan, Yongsong Ye, Bo Liu

“…The ALFF value in the right superior parietal lobule during real taVNS was negatively correlated with the Unified Parkinson’s Disease Rating Scale Part III (r = −0.417, p = 0.004, Bonferroni corrected).ConclusionTaVNS could immediately modulate the functional activity of brain regions involved in superior parietal lobule, precentral gyrus, postcentral gyrus, middle occipital gyrus, and cuneus. …”
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Event-related theta synchronization over sensorimotor areas differs between younger and older adults and is related to bimanual motor control by Andreas Wulff-Abramsson, Ana Zvornik, Keenie Ayla Andersen, Yan Yang, Mikael Novén, Jesper Lundbye-Jensen, Leo Tomasevic, Anke Ninija Karabanov

“…Together, the results show that theta ERS over sensorimotor areas is a strong, age-sensitive marker of dynamic pinch force adjustments showing an age-related reduction in specificity with reduced context-dependent modulations and more imbalanced bimanual activation.…”
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Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019 by Saeid Safiri, Jessica A. Grieger, Amir Ghaffari Jolfayi, Seyed Ehsan Mousavi, Seyed Aria Nejadghaderi, Asra Fazlollahi, Mark J. M. Sullman, Nahid Karamzad, Fikrettin Sahin, Kuljit Singh, Gary S. Collins, Ali-Asghar Kolahi

“…This trend aligns with socio-demographic indices and is influenced by the physical activity levels and dietary habits of these populations.…”
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Natural pigments: innovative extraction technologies and their potential application in health and food industries by Ayu Masyita, Gemala Hardinasinta, Ayun Dwi Astuti, Firdayani Firdayani, Dian Mayasari, Aki Hori, Ira Nur Ainun Nisha, Firzan Nainu, Takayuki Kuraishi

“…Beyond their color properties, these pigments possess several biological activities, including antioxidant, anti-inflammatory, anticancer, antibacterial, and neuroprotective effects, as well as benefits for eye health. …”
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Impact of prior CAR T-cell therapy on mosunetuzumab efficacy in patients with relapsed or refractory B-cell lymphomas by Elise A. Chong, Elicia Penuel, Ellen B. Napier, Rachel K. Lundberg, Lihua E. Budde, Mazyar Shadman, Matthew J. Matasar, Nancy L. Bartlett, Ian W. Flinn, Francesc Bosch, Keith Fay, Andre Goy, Anita Kumar, Loretta J. Nastoupil, Michael C. Wei, Mei Wu, Shen Yin, Joseph A. Fraietta, Emeline R. Chong, Stephen J. Schuster

“…Additionally, responding patients had an increase in activated CD8 cells (median fold change, 1.7; P = .02). …”
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Trial of alginates in throat symptoms: protocol for a pragmatic, multicentre, placebo controlled, double blind, parallel, randomised controlled trial of liquid alginate (Gaviscon A... by David Hamilton, Ruth Wood, Dawn Teare, Miranda Morton, Rebecca Maier, James O’Hara, Tony Fouweather, Julian McGlashan, Julie Thompson, Richard Joyce, Hesther Smith, Lysbeth Evans

“…All participants will provide informed consent prior to any trial specific activity taking place. Results will be disseminated in peer reviewed publications, at national and international conferences, in peer reviewed journals and to participants and the public (using lay language).Trial registration number ISRCTN13949559…”
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Assessment of Protein Quality and Nutritional Characteristics of Commonly Consumed Pulses in the Caribbean Diet by Different In Vitro Assays by Daniel J. Thomas, Zhanhui Lu, Yolanda Brummer, Yan Zhu, Ronghua Liu, Lili Mats, Rong Tsao, D. Dan Ramdath, Matthew G. Nosworthy

“…While total phenolic content (TPC) and antioxidant activity were reduced with cooking, they were within expected ranges for cooked pulse flours; however, they were higher in bean (<i>P. vulgaris</i>) varieties than cowpea and pigeon pea. …”
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Dual-functional passivation on highly-efficient air-processed FAPbI₃ perovskite solar cells fabricated under high humidity without auxiliary equipment by Bo-Tau Liu, His-Sheng Su, I-Ru Chen, Rong-Ho Lee, Yi-Fang Su, Kai-Ting Sun, Shoaib Siddique

“…Formamidinium lead triiodide (FAPbI3) perovskite has garnered significant attention due to its narrow bandgap and excellent thermal stability. However, the photo-active α-phase FAPbI3 suffers the poor structural stability, easily transforming to photo-inactive δ-phase FAPbI3 at room temperature, a process that is accelerated by the moisture. …”
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Body composition as an indicator of metabolic changes in mice obtained by <i>in vitro</i> fertilization by M. V. Anisimova, Yanli Gon, G. V. Kontsevaya, A. V. Romashchenko, N. V. Khotskin, A. K. Stanova, L. A. Gerlinskaya, M. P. Moshkin

“…Since adipose tissue contributes significantly less to total energy intake compared to muscle, the main component of lean mass, it is not surprising that at the same level of IVF locomotor activity offspring consumed less food than controls. …”
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Fertigation with alpha-tocopherol enhances morphological, physiological, and antioxidant responses in radish (Raphanus sativus L.) under drought stress by Muhammad Shahbaz Chishti, Muhammad Shahbaz, Muhammad Kaleem, Saba Shafi, Anam Mehmood, Zhang Qingzhu, Musarat Mansha, Nimra Shehzadi, Shamsa Rana, Hina Shahid, Abeer Hashem, Alanoud Alfagham, Elsayed Fathi Abd-Allah

“…Also, the α-Toc enhanced the photosynthetic pigments and significantly increased photosynthetic activity in the Early Milo (G2) as compared to Laal Pari (G1) genotype under drought, enhancing water use efficiency by maintaining transpiration rate and stomatal conductance. …”
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Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review by Irfan Anjum, Ayesha Nasir, Faiza Naseer, Faiza Naseer, Ahsan Ibrahim, Bisma Rehman, Fawad Bashir, Qura Tul Ain

“…Further investigations of these phytochemicals can provide intuition regarding the development of newer drug molecules having exclusive activity for attenuating interstitial cystitis.…”
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Energetic and genomic potential for hydrogenotrophic, formatotrophic, and acetoclastic methanogenesis in surface-expressed serpentinized fluids of the Samail Ophiolite by Alta E. G. Howells, Alta E. G. Howells, Lilja M. Quinn, Lilja M. Quinn, Miguel G. Silva, Miguel G. Silva, Kylie Akiyama, Kylie Akiyama, Lucas M. Fifer, Lucas M. Fifer, Grayson Boyer, Srishti Kashyap, Kirt Robinson, Kirt Robinson, Jared Broddrick, Everett L. Shock, Tori M. Hoehler

“…Previous work indicates the occurrence of methanogenesis in fluids from the actively serpentinizing Samail Ophiolite in the Sultanate of Oman. …”
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Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

“…We also demonstrated that CEMIP restricted CD8+ T-cell antitumor activities both in vitro and in vivo due to impaired MHC-I-mediated antigen presentation. …”
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Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids by Xin-Ru Wen, Jia-Wei Tang, Jie Chen, Hui-Min Chen, Muhammad Usman, Quan Yuan, Yu-Rong Tang, Yu-Dong Zhang, Hui-Jin Chen, Liang Wang

“…Gradient-weighted class activation mapping (Grad-CAM) was used to highlight important regions in the images for prediction. …”
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Identification and validation of diagnostic genes IFI44 and IRF9 in insomnia-associated autoimmune uveitis by Chao Wu, Hui Feng, Meng Tian, Baorui Chu, Xianyang Liu, Shuhao Zeng, Yakun Wang, Hong Wang, Shengping Hou, Qingfeng Liang

“…Finally, molecular docking was applied to verify binding activities.ResultsWe identified 138 up-regulated and 85 down-regulated DEGs that were common to insomnia and AU. …”
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Long-term smoking contributes to aging frailty and inflammatory response by Huijin Hou, Yidi Chai, Ting Zhang, Yue Liang, Lan Huang, Xu Cao, Shufang Liang

“…Mechanistically, this up-regulation activates the NF-κB signaling pathway. Our findings quantitatively link smoking-induced frailty to increased levels of TNF-α and IL-1β, providing experimental evidence for the diagnosis and prevention of frailty in elderly populations. …”
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HDL Particle Size and Functionality Comparison between Patients with and without Confirmed Acute Myocardial Infarction by Raissa de Miranda Teixeira, Nicole Cruz de Sá, Ana Paula Caires dos Santos, Vanessa Rocha Anjos e Silva, Elaine Christine de Magalhães Cabral Albuquerque, Luiz Claudio Lemos Correia, Ricardo David Couto

“…The paraoxonase-1 (PON-1) activity was determined in a spectrophotometer by using paraoxon as a substrate. …”
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East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol by Michael Doherty, Roshan das Nair, Ana Valdes, Reuben Ogollah, Paul Greenhaff, Bonnie Millar, Michelle Hall, Amy Fuller, Polykarpos Angelos Nomikos, David A Walsh, A Abhishek

“…Qualitative interviews will be conducted with a sample of participants from each of the two active intervention arms.Ethics and dissemination This protocol was approved by the East Midlands-Derby Research Ethics Committee (18/EM/0288) and registered at ClinicalTrials.gov (protocol v4.0, 10/02/2020). …”
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Basic Characteristics of Ionic Liquid-Gated Graphene FET Sensors for Nitrogen Cycle Monitoring in Agricultural Soil by Naoki Shiraishi, Jian Lu, Fatin Bazilah Fauzi, Ryo Imaizumi, Toyohiro Tsukahara, Satoshi Mogari, Shosuke Iida, Yusuke Matsukura, Satoshi Teramoto, Keisuke Yokoi, Izumi Ichinose, Mutsumi Kimura

“…However, some nitrogen is converted to nitrous oxide (N₂O), a greenhouse gas with a warming potential about 300-times greater than carbon dioxide (CO₂). Agricultural activities are the main source of N₂O emissions. …”
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GPIHBP1 increase accounts for rheumatic arthritis-related hypotriglyceridemia by facilitating lipids uptake of white adipose tissues by Meng-Ke Song, Meng-Fan Gu, Ling Liu, Lian-Jun He, Peng Ye, Kui Yang, Dan-Dan Wang, Opeyemi Joshua Olatunji, Qin Yin, Jian Zuo

“…Both HUVEC cells co-culture and GPIHBP1 supplement reduced LPL distribution on pre-adipocytes, and eliminated LPL activity difference between normal and RA serum-treated cells. …”
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