Space and Time Resolved Detection of Platelet Activation and von Willebrand Factor Conformational Changes in Deep Suspensions by Jacopo Biasetti, Kaushik Sampath, Angel Cortez, Alaleh Azhir, Assaf A. Gilad, Thomas S. Kickler, Tobias Obser, Zaverio M. Ruggeri, Joseph Katz

“…Anti-P-Selectin FITC-conjugated antibodies and the calcium-sensitive probe Indo-1 are used to detect activated platelets. A positive correlation between the mean number of platelets detected per image and the percentage of activated platelets determined through flow cytometry is obtained, validating the technique. …”
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Biologic Agents in Crohn’s Patients Reduce CD4+ T Cells Activation and Are Inversely Related to Treg Cells by Eliane Aparecida Rosseto-Welter, Leticia D’argenio-Garcia, Filipa Blasco Tavares Pereira Lopes, Ana Eduarda Zulim Carvalho, Fernando Flaquer, Vanessa Severo-Lemos, Claudia Concer Viero Nora, Flavio Steinwurz, Lucas Pires Garcia Oliveria, Thiago Aloia, Luiz Vicente Rizzo, Cristóvão Luis Pitangueira Mangueira, Karina Inacio Carvalho

“…To examine the immune status in a Brazilian cohort, we analyzed CD4+ T cells, activation status, cytokine production, and Treg cells in blood of Crohn’s patients. …”
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Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn. by Kalaisezhiyen Pavithra, Sasikumar Vadivukkarasi

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Antiemetic activity of Sesamol possibly through serotonergic and dopaminergic receptor interaction pathways: In vivo and in silico studies by Touhidul Islam Tanim, Ayman M. Al-Qaaneh, Raihan Chowdhury, Md. Shimul Bhuia, Tabassum Islam, Md Showkoth Akbor, Md. Tahajul Islam, Md. Mohasin Miah, Ali Raza Ishaq, Mostafa A. Abdel-Maksoud, Mohamed A. El-Tayeb, Mohamed El-Shazly, Muhammad Torequl Islam, Heba A.S. El-Nashar

“…This study aimed to evaluate the antiemetic activity of SEL, supported by in vivo and in silico studies. …”
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Neurocognitive Impairment in HIV-Infected Naïve Patients with Advanced Disease: The Role of Virus and Intrathecal Immune Activation by Monica Airoldi, Alessandra Bandera, Daria Trabattoni, Benedetta Tagliabue, Beatrice Arosio, Alessandro Soria, Veronica Rainone, Giuseppe Lapadula, Giorgio Annoni, Mario Clerici, Andrea Gori

“…To investigate intrathecal immune activation parameters and HIV-RNA in HIV-associated neurocognitive disorders (HAND) of advanced naïve HIV-infected patients and to evaluate their dynamics before and after initiation of antiretroviral therapy (ART). …”
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ANTIBACTERIAL ACTIVITY OF NAMNAM FRUIT JUICE FROM SOUTH KALIMANTAN AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI by Nurbidayah, Nafila, Nurul Amalia

“…It meant that the higher the concentration, the greater the inhibition zone and the stronger the antibacterial activity produced. Namnam fruit juice activity in inhibiting the growth of E. coli bacteria was more substantial when compared to S. aureus bacteria. …”
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Circulating Total and Active Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinases-1 in Patients with Systemic Lupus Erythomatosus

“…<p>We investigated the serum concentration of total metalloproteinase-9 (tMPP-9), active MMP-9 (aMMP-9), and tissue inhibitor of metalloproteinase-1 (TIMP-1) in a group of 41 patients with SLE and 20 healthy controls. …”
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On the Issue of Foreign Policy Activities of Buddhists of the USSR in the Context of the Religious Policy of the Soviet State (1950s–1970s) by Alexey V. Gorbatov

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Synthesis, X-Ray Crystal Structures, and Preliminary Antiproliferative Activities of New s-Triazine-hydroxybenzylidene Hydrazone Derivatives by Assem Barakat, Fardous F. El-Senduny, Zainab Almarhoon, Hessa H. Al-Rasheed, Farid A. Badria, Abdullah Mohammed Al-Majid, Hazem A. Ghabbour, Ayman El-Faham

“…From the eighteen compounds, which have been examined, only two derivatives having piperidine moiety showed more selectivity against the two cell lines MCF-7 and HCT-116, while the others showed very weak activity. The position of the hydroxyl group in the benzylidine ring and the substituent on the s-triazine moiety has great effect on the activity of the prepared compounds. …”
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Synthesized Phosphonium Compounds Demonstrate Resistant Modulatory and Antibiofilm Formation Activities against Some Pathogenic Bacteria by Cedric Dzidzor Kodjo Amengor, Cynthia Amaning Danquah, Emmanuel Bentil Asare Adusei, Francis Klenam Kekessie, Francis Ofosu-Koranteng, Paul Peprah, Benjamin Kingsley Harley, Emmanuel Orman, Joseph Adu, Yussif Saaka

“…Compounds P-MEOXY (1) and 2ET-TOL (2) exhibited mild activity against P. aeruginosa with compound 4 showing antimycobacterial activity at 500 µg/mL.…”
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Optimizing conditions to improve polyphenol content and screening antioxidant capacity with DNA protection activity of Perilla frutescens by Ngoc Thien Kim Nguyen, Huynh Anh Vu Truong, Hoang Khue Tu Nguyen

“…Britt is a good source showing DNA protection and antioxidant activity for healthcare. …”
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Legal Regulation of the Activities of the Bodies of the National Police of Ukraine on Ensuring the Exercise of the Right to Freedom of Peaceful Assembly by M. A. Sambor

“…Under the conditions set out in Part 2 of Art. 19 of the Constitution of Ukraine of the legal order in Ukraine, according to which state bodies to which the National Police of Ukraine belongs, their officials are obliged to act only on the basis, within the powers and in the manner provided by the Constitution and laws of Ukraine, is usually an important issue regulatory and legal regulation of the activities of the bodies of the National Police of Ukraine on ensuring the exercise of the right to freedom of peaceful assembly. …”
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The effect of nuclear transcriptional factor κВ activation inhibitor – curcumine on the experimental immune liver disease by I. N. Alekseyeva, N. V. Makogon, S. I. Pavlovich, T. M. Bryzgina, L. I. Aleksyuk, T. V. Martynova, V. S. Sukhina

“…To study at two models of immune hepatitis (Т-cellular and antibody origin) in mice damage of the liver, activity and destruction of its immunocompetent cells, thymus gland and the spleen, as well as the effect of curcumine — inhibitor of NF-κB activation on development of pathological process.Material and methods. …”
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Phytochemical Constituents and Biological Activities of Jasonia glutinosa L.: The First Report for the Plant Growing in North Africa by Hamdoon A. Mohammed, Abdulnaser Kh. Abdulkarim, Abdullah D. Alamami, Fatma A. Elshibani

“…The current study is the first report for the plant species growing in Libya and aims to investigate the phytochemical constituents, antioxidant, cytotoxic, and antimicrobial activities of the plant’s aqueous ethanolic extract. …”
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Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity by R. Babu, Manokaran Veeramani, Wallepure Aadinath, Vignesh Muthuvijayan, Shailja Singh, Smita Srivastava

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Dissociation between Cerebellar and Cerebral Neural Activities in Humans with Long-Term Bilateral Sensorineural Hearing Loss by Xiao-Min Xu, Yun Jiao, Tian-Yu Tang, Jian Zhang, Chun-Qiang Lu, Ying Luan, Richard Salvi, Gao-Jun Teng

“…Abnormal neural activity in the cerebellum has been implicated in hearing impairments, but the effects of long-term hearing loss on cerebellar function are poorly understood. …”
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Supporting older adults with mobility disabilities through voice-activated digital assistants and smart home technologies by Jaewon Kang, Emma Lachs, Kathryn Huang, Laura A. Rice, Wendy A. Rogers

“…Voice-activated digital assistants and smart home technologies are potential solutions to support older adults. …”
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Antibiofilm activity of 3,3'-diindolylmethane on Staphylococcus aureus and its disinfection on common food-contact surfaces by Hui Zhang, Xiaomei Guo, Lei Tian, Na Wang, Yuqing Li, Ariel Kushmaro, Robert Marks, Qun Sun

“…DIM in the concentration range of 31.2−62.5 μmol/L demonstrated a dose-dependent antibiofilm activity to S. aureus, as confirmed by light microscopic (LM), confocal laser scanning microscopic (CLSM), and scanning electron microscopic (SEM) analyses. …”
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Efficiency of Disease and Disease Activity Diagnosis Models of Systemic Lupus Erythematosus Based on Protein Array Analysis by Yafei Zhao, Yuanyuan Qi, Xinran Liu, Yan Cui, Zhanzheng Zhao

“…Additionally, the three protein biomarkers contained in the disease activity distinguish model provided additional benefit to conventional biomarkers in predicting active lupus. …”
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New Urea and Thiourea Derivatives of Piperazine Doped with Febuxostat: Synthesis and Evaluation of Anti-TMV and Antimicrobial Activities by Reddivari Chenna Krishna Reddy, Syed Rasheed, Devineni Subba Rao, Shaik Adam, Yellala Venkata Rami Reddy, Chamarthi Naga Raju

“…Compound 4 was synthesized in high yields (94%) by the condensation reaction of febuxostat (1) with piperazine using a selective reagent such as propylphosphonic anhydride (T3P). Antiviral activity against Tobacco mosaic virus (TMV) and antimicrobial activity of the synthesized compounds were evaluated. …”
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