Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant by Patsy R Tomlinson, Rachel G Knox, Olga Perisic, Helen Su, Gemma V Brierley, Roger L Williams, Robert K Semple

“…Constitutional PIK3R1 mutations cause diseases with a genotype-phenotype relationship not yet fully explained: heterozygous loss-of-function mutations cause SHORT syndrome, featuring insulin resistance and short stature attributed to reduced p110α function, while heterozygous activating mutations cause immunodeficiency, attributed to p110δ activation and known as APDS2. …”
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Active Control for Multinode Unbalanced Vibration of Flexible Spindle Rotor System with Active Magnetic Bearing by Xiaoli Qiao, Guojun Hu

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Effects of Textural Properties and Surface Oxygen Content of Activated Carbons on the Desorption Activation Energy of Water by Xin Li, Zhong Li, Qibin Xia, Hongxia Xi, Zhenxia Zhao

“…This work mainly describes investigations of the effects of pore structure and oxygen content of activated carbons on the desorption activation energy, E d , of water. …”
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Evaluation of physical fitness parameters of hearing impaired adolescents who are active and non-active in sports by A. Uludag, Erkan Calıskan, Ozge Caglar, Tulin Sepetcı

“…The aim of this study is evaluate the physical fitness parameters of 9 – 17 years old hearing impaired adolescentswho were active and non active in sports. The study was included totally 65 students attended to the Kepezhearing impaired school; 40 (26 male, 14 female) active in sports (participating the team sports at least 3 days aweek) with the mean age of 12.85 ± 2.83 years and 25 (14 male, 11 female) non- active in sports with the mean ageof the 11.48 ± 3.20 years. …”
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Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity by Jan H Kirchner, Lucas Euler, Ingo Fritz, André Ferreira Castro, Julijana Gjorgjieva

“…Here, we propose a mechanistic model in which dendrite growth and the organization of synapses arise from the interaction of activity-independent cues from potential synaptic partners and local activity-dependent synaptic plasticity. …”
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Understanding the Activation of Platelets in Diabetes and Its Modulation by Allyl Methyl Sulfide, an Active Metabolite of Garlic by Navya Malladi, Ebin Johny, Shravan K. Uppulapu, Vikas Tiwari, Md Jahangir Alam, Ramu Adela, Sanjay K. Banerjee

“…We have evaluated the effect of allyl methyl sulfide on platelet activation by administrating AMS to diabetic rats for 10 weeks. …”
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Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus by Nathalie Wurtz, Issam Hasni, Audrey Bancod, Bernard La Scola

“…Ionised active water S-100® has been proposed as an original solution for use in dermocosmetics and for the treatment of wounds such as burns and atopic dermatitis. …”
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Active Aging: Exploration into Self-Ratings of “Being Active,” Out-of-Home Physical Activity, and Participation among Older Australian Adults Living in Four Different Settings by Rosemary L. Aird, Laurie Buys

“…We examined whether self-ratings of “being active” among older people living in four different settings (major city high and lower density suburbs, a regional city, and a rural area) were associated with out-of-home participation and outdoor physical activity. …”
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Plasticizers May Activate Human Hepatic Peroxisome Proliferator-Activated Receptor α Less Than That of a Mouse but May Activate Constitutive Androstane Receptor in Liver by Yuki Ito, Toshiki Nakamura, Yukie Yanagiba, Doni Hikmat Ramdhan, Nozomi Yamagishi, Hisao Naito, Michihiro Kamijima, Frank J. Gonzalez, Tamie Nakajima

“…Dibutylphthalate (DBP), di(2-ethylhexyl)phthalate (DEHP), and di(2-ethylhexyl)adipate (DEHA) are used as plasticizers. Their metabolites activate peroxisome proliferator-activated receptor (PPAR) α, which may be related to their toxicities. …”
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Exploring activist perspectives on Indigenous-settler solidarity in Toronto’s food sovereignty movement by Taliya Seidman-Wright, Sarah Rotz

Subjects: “…Activism…”
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Suprema Corte e segregação racial nos moinhos da Guerra Fria by Sandro Luís Tomás Ballande Romanelli, Fabrício Ricardo de Limas Tomio

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Mainstreaming Conservative Ideas Through Media Coverage by Anamaria Hanžek

Subjects: “…Men’s Rights Activism…”
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Spatial Politics and a Native American Reservation: Reading Red Power: A Graphic Novel with Author Brian Wright-McLeod by Kristina Aurylaite

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Çevresel Aktivizm, Halkla İlişkiler ve Yeşil Aklama Üzerine Kuramsal Bir Bakış by Aybike Özel

Subjects: “…environmental activism…”
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Constitutive Expression of Functionally Active Protease-Activated Receptors 1 and 2 in Human Conjunctival Epithelial Cells by Timothy J. Nickel, Mohammad H. Kabir, Jaya Talreja, Daniel J. Stechschulte, Kottarappat N. Dileepan

“…Protease-activated receptors (PARs) are G-protein-coupled receptors which initiate inflammatory responses when activated by specific serine proteases. …”
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Chlorogenic acid inhibits NLRP3 inflammasome activation through Nrf2 activation in diabetic nephropathy by Liping Bao, Yuhan Gong, Wenji Xu, Jun Dao, Jinjin Rao, Haihui Yang

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The Effect of Supplementing Mushroom Growing Substrates on the Bioactive Compounds, Antimicrobial Activity, and Antioxidant Activity of Pleurotus ostreatus by Senzosenkosi Surprise Mkhize, Mthokozisi Blessing Cedric Simelane, Ishmael Nkoana Mongalo, Ofentse Jacob Pooe

“…Pleurotus ostreatus mushroom contains important bioactive compounds and has several biological activities; however, mushroom growing substrates have major influence on chemical and functional characteristics of the mushroom. …”
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Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors by Xiaoyan Sheng, Yuebo Zhang, Zhenwei Gong, Cheng Huang, Ying Qin Zang

“…Peroxisome proliferator-activated receptors (PPARs) are transcriptional factors involved in the regulation of insulin resistance and adipogenesis. …”
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Bio-active composition, antibacterial activity and molecular docking studies of Salicia nitida (Benth.) root extracts by Wisdom U. Ike, Okereke C. Stanley, Nosiri Ijeoma, Okamgba C. Okezie, Nwokocha W. Osita, Aguwanba Chinedu, Aaron C. Friday

“…The phytochemical and GC-MS findings suggest that Salicia nitida root extracts contain bioactive constituents which are known to exhibit physiological activities. More so, stable complexes were formed between Class A beta-lactamase enzyme (PDB: 3BLM), Butylated hydroxytoluene (CID: 31404) and 5-Eicosene (CID: 5364600), at different positions, indicating strong and favorable interactions. …”
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The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease by Paulina Jakubczyk, Piotr Widera, Justyna Helis, Maciej Michalik, Aleksandra Buczek, Hubert Bigajski, Aleksandra Banaś, Olga Bilczewska, Wiktoria Janik, Marta Handschuh

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