Intravenous nicardipine and labetalol use in hypertensive patients with signs or symptoms suggestive of end-organ damage in the emergency department: a subgroup analysis of the CLU... by Brian Hiestand, Phillip Levy, W Frank Peacock, Brigitte M Baumann, Richard M Nowak, Amy Hsu, Joseph Varon, Chad M Cannon, David M Cline, Pierre Borczuk, Abhinav Chandra, Deborah B Diercks, Preeti Jois, Brian Kaminski, Jon W Schrock

“…Objective To compare the efficacy of Food and Drug Administration recommended dosing of nicardipine versus labetalol for the management of hypertensive patients with signs and/or symptoms (S/S) suggestive of end-organ damage (EOD).Design Secondary analysis of the multicentre prospective, randomised CLUE trial.Setting 13 academic emergency departments in the USA.Participants Eligible patients had two systolic blood pressure (SBP) measures ≥180 mm Hg at least 10 min apart, no contraindications to nicardipine or labetalol and predefined S/S suggestive of EOD on arrival.Interventions Medications were administered by continuous infusion (nicardipine) or repeat intravenous bolus (labetalol) for a study period of 30 min or until a specified target SBP ±20 mm Hg was achieved.Primary outcome measure Percentage of participants achieving a predefined target SBP range (TR) defined as an SBP within ±20 mm Hg as established by the treating physician.Results Of the 141 eligible patients, 49.6% received nicardipine, 51.7% were women and 81.6% were black. …”
Get full text

Cesarean section in Suriname using robson classification: a two-year nationwide cross-sectional study on rates, risk factors and perinatal outcomes of cesarean section by Zita D. Prüst, Josephine A. I. Dupont, Safir Liesdek, Kitty W. M. Bloemenkamp, Thomas van den Akker, Kim J. C. Verschueren, Lachmi R. Kodan

Get full text

Evaluation of Medical Care for Diabetic and Hypertensive Patients in Primary Care in Mexico: Observational Retrospective Study by Agustin Lara-Esqueda, Sergio A. Zaizar-Fregoso, Violeta M. Madrigal-Perez, Mario Ramirez-Flores, Daniel A. Montes-Galindo, Margarita L. Martinez-Fierro, Iram P. Rodriguez-Sanchez, José Guzman-Esquivel, Carmen Meza-Robles, Gabriel Ceja-Espiritu, Pablo A. Kuri-Morales, Josuel Delgado-Enciso, Armando Barriguete-Melendez, Hector R. Galvan-Salazar, Carlos E. Barajas-Saucedo, Elvin Guillermo-Espinosa, Agustin D. Lara-Basulto, Jesus F. Gonzalez-Roldan, Ivan Delgado-Enciso

Get full text

Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2... by Claudia Volecker-Rehage, Uros Marusic, Bettina Wollesen, Antoine Langeard, Tamar Yellon, Anna Wunderlich, Vera Belkin, Guoping Qian, Eleftheria Giannouli, Zbigniew Ossowski, Rafael A. Bernades, Yael Netz, Rajesh Sighdel

Get full text

Ten simple rules for working with high resolution remote sensing data by Mahood, Adam L., Joseph, Maxwell B., Spiers, Anna I., Koontz, Michael J., Ilangakoon, Nayani, Solvik, Kylen K., Quarderer, Nathan, McGlinchy, Joe, Scholl, Victoria M., St. Denis, Lise A., Nagy, Chelsea, Braswell, Anna, Rossi, Matthew W., Herwehe, Lauren, Wasser, Leah, Cattau, Megan E., Iglesias, Virginia, Yao, Fangfang, Leyk, Stefan, Balch, Jennifer K.

“…In order to implement a consistent strategy, we outline ten rules with examples from Earth and environmental science to help academic researchers and professionals in industry work more effectively and competently with high-resolution data. …”
Get full text

Compensatory increase in oxygen extraction fraction is associated with age-related cerebrovascular disease by John McFadden, Julian Matthews, Lauren Scott, Karl Herholz, Ben Dickie, Hamied Haroon, Oliver Sparasci, Saadat Ahmed, Natalia Kyrtata, Geoffrey J.M. Parker, Hedley C.A. Emsley, Joel Handley, Maélène Lohezic, Laura M. Parkes

Get full text

Assessment of the general population knowledge about the emergence of Nipah virus outbreak in Bangladesh: A nationwide cross-sectional study by Mobin Ibne Mokbul, Shuvajit Saha, Samiha Nahar Tuli, Fatema Binte Nur, A.M. Khairul Islam, Tariful Islam, Shirsho Shreyan, Alok Bijoy Bhadra, Golam Dastageer Prince, Irfath Sharmin Eva, Mustari Nailah Tabassum, Ferdous Wahid, Md Irfan Bin Kayes, Nazim Hassan Ziad, Mohammad Delwer Hossain Hawlader

Get full text

Factors associated with caffeine intake among undergraduates: a cross-sectional study from Palestine by May Hamdan, Souzan Zidan, Fatima Al-Amouri, Hiba Niroukh, Manar Abu Dawod, Sajeda Ashour, Shahd Sameer Dweik, Manal Badrasawi

“…The sample was distributed almost equally between the first (26.3%), second (23.0%), third (22.8%), and fourth (18.7%) academic years, and only 44 undergraduates (9.1%) were in their fifth year. …”
Get full text

Social determinants and follow-up care after emergency department discharge for traumatic intracranial hemorrhage by Meghan M. Dillan, Joseph Piktel, Adam Perzynski, Mary Jo Roach, Kristen K. Curtis, Yasir Tarabichi, Lance Wilson, Michael L. Kelly

“…Background: Traumatic brain injury (TBI) is a multifaceted condition associated with occupational, social, physical, cognitive, academic, and economic burdens. Mild TBI including traumatic intracranial hemorrhage (tICH), is commonly discharged from the emergency department (ED). …”
Get full text

Rationale and design of APOLLO: a personalized rehAbilitation PrOgram in aLLOgeneic bone marrow transplantation by Edith Pituskin, Stephen Foulkes, Rachel J. Skow, Thomas McMurtry, Calvin Kruger, Janet E. Bates, Daena Lamoureux, Joseph Brandwein, Elena Lieuw, Cynthia Wu, Nancy Zhu, Peng Wang, Daniel Sawler, Minakshi Taparia, Marlene Hamilton, Tiffany Comfort-Riddle, Tara Meyer, Gabor T. Gyenes, Ian Paterson, Carla M. Prado, Mark J. Haykowsky, Justin G. Greiner, Margaret L. McNeely, Puneeta Tandon, Richard B. Thompson

“…In Canada, dedicated cancer-specific rehabilitation programs are available only at major tertiary academic centers. Methods The primary aim of this study will evaluate the feasibility and acceptability of a multimodal care navigation (nursing, exercise, nutrition) intervention with content delivery facilitated by a supportive care web-based ‘app’ extending from diagnosis to 1 year in the allogeneic bone marrow transplant population. …”
Get full text

Modulation of brain activity in brain-injured patients with a disorder of consciousness in intensive care with repeated 10-Hz transcranial alternating current stimulation (tACS): a... by David Williamson, Francis Bernard, Stefanie Blain-Moraes, Caroline Arbour, Virginie Williams, Louis de Beaumont, Catherine Duclos, Béatrice P De Koninck, Daphnee Brazeau, Amelie A Deshaies, Marie-Michele Briand, Charlotte Maschke

“…The findings of this two-phase study will be submitted for publication in a peer-reviewed academic journal and submitted for presentation at conferences. …”
Get full text

Designing an Innovative Human Resources Model Based on Perceived Organizational Support Case Study of Qazvin's Government organizations by Hossein Rasouli, Morteza Mousakhani, Mahdi Alvani, parham azimi

“…In this phase, the statistical sample, carefully chosen using a non-probability targeted method, included a select group of 11 academic and organizational experts. The quantitative segment focused on a diverse group of managers, deputies, and specialists from various government organizations across Qazvin, encompassing sectors such as governance, infrastructure, economic, social, cultural, and service affairs. …”
Get full text

Precession modulates the poleward expansion of atmospheric circulation to the Arctic Ocean by Yi Zhong, Zhengyao Lu, Stefanie Kaboth-Bahr, Jimin Yu, Keiji Horikawa, Mark J. Dekkers, Juan C. Larrasoaña, Peter D. Clift, Michael E. Weber, Flor Vermassen, Sev Kender, Chijun Sun, Hu Yang, Xianfeng Wang, Camilla S. Andresen, Yanguang Liu, Haiwei Zhang, Zhengyang Dai, Lu Niu, Jingyu Zhang, Xuguang Feng, Debo Zhao, Wenyue Xia, Sheng Yang, Hai Li, Qingsong Liu

Get full text

Percutaneous Coronary Intervention Complexity and Risk of Adverse Events in relation to High Bleeding Risk among Patients Receiving Drug-Eluting Stents: Insights from a Large Singl... by Hao-Yu Wang, Yang Wang, Dong Yin, Run-Lin Gao, Yue-Jin Yang, Bo Xu, Ke-Fei Dou

“…The primary ischemic endpoint was major adverse cardiovascular events (MACE) (composite of cardiac death, myocardial infarction, definite/probable stent thrombosis, and target lesion revascularization), and primary bleeding endpoint was Bleeding Academic Research Consortium (BARC) type 2, 3, or 5 bleeding. …”
Get full text

Ear Infection and Its Associated Risk Factors in First Nations and Rural School-Aged Canadian Children by Chandima P. Karunanayake, William Albritton, Donna C. Rennie, Joshua A. Lawson, Laura McCallum, P. Jenny Gardipy, Jeremy Seeseequasis, Arnold Naytowhow, Louise Hagel, Kathleen McMullin, Vivian Ramsden, Sylvia Abonyi, Jo-Ann Episkenew, James A. Dosman, Punam Pahwa, The First Nations Lung Health Project Research Team, The Saskatchewan Rural Health Study Team

Get full text

ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

Get full text

The Equator Project Research School and Mentoring Network: Evaluated Interventions to Improve Equity in Geoscience Research by Natasha Dowey, Anya Lawrence, Munira Raji, Christopher Jackson, Rebecca Williams, Ben Fernando, Sam Giles, Jenni Barclay, Louisa Brotherson, Ethny Childs, Jacqueline Houghton, Anjana Khatwa, Keely Mills, George Jameson, Francisca Rockey, Steven Rogers, Catherine Souch

“…The Equator Research School brought together 30 Black, Asian and minority ethnic students in GEES, and 12 academics, professionals and mentors, from across the UK for a 5-day residential workshop in April 2022. …”
Get full text

Effectiveness of using implementation frameworks to facilitate the implementation of a stroke management guideline in the traditional Chinese medicine hospitals in China: protocol... by Zhuo Chen, Yefeng Cai, Wenjun He, Yiyuan Cai, Lingrui Liu, Qing Zhao, Sensen lv, Dong (Roman) Xu, Chun Hao, Lanping Zhang, Pengfei Guo, Yuning Shi

“…The results will be published in peer-reviewed academic journals and presented at national and international conferences to inform future practice and policy on the integration of TCM and Western medicine for stroke management.Trial registration details This study has been registered on the Open Science Framework with the DOI: 10.17605/OSF.IO/NJEVB.…”
Get full text

Effect of static magnetic field on microstructure and mechanical property of AlSi10Mg alloy by laser directed energy deposition by Weiming Niu, Bingke Song, Jiasen Han, Haiou Yang, Zhaopu Yao, Hui Chen, Xin Lin

Get full text

Exploraciones personales sobre las condiciones precedentes de la violencia sexual en el marco del conflicto armado enColombia by Paula Natalia Rincón Chitiva, Juan Felipe Monroy Simbaqueba

“…The research invokes the use of literary tools (four short stories written by us) and states through non-academic language of the personal repercussions during the realization of this investigation.…”
Get full text