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  1. 4621
  2. 4622

    Residue-resolved insights into the stabilization of therapeutic proteins by excipients: A case study of two monoclonal antibodies with arginine and glutamate by Tobias M. Prass, Patrick Garidel, Lars V. Schäfer, Michaela Blech

    Published 2024-12-01
    “…Here, we describe a combined experimental and computational approach for investigating the effect of protein–excipient interactions on formulation stability, which allows the identification of preferential interaction sites and thus can aid in the selection of excipients to be experimentally screened. …”
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  3. 4623

    Target Threat Assessment in Air Combat Based on Improved Glowworm Swarm Optimization and ELM Neural Network by Yuan Cao, Ying-Xin Kou, An Xu, Zhi-Fei Xi

    Published 2021-01-01
    “…Target threat assessment technology is one of the key technologies of intelligent tactical aid decision-making system. Aiming at the problem that traditional beyond-visual-range air combat threat assessment algorithms are susceptible to complex factors, there are correlations between assessment indicators, and accurate and objective assessment results cannot be obtained. …”
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  4. 4624
  5. 4625

    Anomalous Long‐Distance Propagation of ILS LOC Signals by the Es Layer and Its Impact on Aviation Receivers by S. Saito, K. Hosokawa, J. Sakai, I. Tomizawa

    Published 2023-11-01
    “…The radio source was identified by receiving the Morse Code for identification as the localizer‐type directional aid (LDA) serving the Runway‐21 of the Hualien Airport, Taiwan (24.0396°N, 121.6221°E) of which beam pointed close to the receiver. …”
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  6. 4626

    Key elements for designing effective second victim support interventions: a focus group study in European clinical settings by José Joaquín Mira, Irene Carrillo, Kris Vanhaecht, Deborah Seys, Massimiliano Panella, Susanna Tella, Katja Schrøder, Reinhard Strametz, Paulo Sousa, Bojana Knezevic, Kaja Pölluste, Eva Gil-Hernández, Hana Knežević Krajina, Sofia Guerra Paiva, Einav Srulovici

    Published 2025-01-01
    “…Analysis of common elements considered key to the success of these programmes was underscored.Results Critical success factors for designing effective SV support interventions included the need for an occupational health approach, the establishment of a strong organisational safety culture, immediate psychological first aid, long-term resilience building, the engagement and training of peer supporters, the provision of adequate resources and ongoing support, the importance of leadership commitment and the necessity of tailoring interventions to the specific context and needs of each institution and country considering their diverse sociocultural and legal framework. …”
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  7. 4627

    Development of a prognostic gene signature and exploration of P4HA1 in the modulation of cuproptosis in colorectal cancer by RenJie Jiang, LinLin Ruan, Taohui Ding, Hongtao Wan, Yanglin Chen, XiaoJian Zhu, Zhijiang Huang, Dengke Yao, Ming Li, Bo Yi, Dan Liu

    Published 2024-12-01
    “…In conclusion, this study proposes a prognostic model based on six cuproptosis-related genes that could aid in personalizing CRC treatment. Furthermore, P4HA1 emerges as a promising therapeutic target.…”
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  8. 4628

    Breast cancer classification based on hybrid CNN with LSTM model by Mourad Kaddes, Yasser M. Ayid, Ahmed M. Elshewey, Yasser Fouad

    Published 2025-02-01
    “…Medical image analysis methods and computer-aided diagnosis can enhance this process, providing training and assistance to less experienced clinicians. …”
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    Article
  9. 4629

    Impact of artificial intelligence in managing musculoskeletal pathologies in physiatry: a qualitative observational study evaluating the potential use of ChatGPT versus Copilot for... by Christophe Ah-Yan, Ève Boissonnault, Mathieu Boudier-Revéret, Christopher Mares

    Published 2025-01-01
    “…Conclusion LLMs, such as ChatGPT and Copilot, can provide reliable medical advice on LBP, irrespective of the detailed clinical context, supporting their potential to aid in patient self-management.…”
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  10. 4630

    Complete genome sequence of Pseudarthrobacter sp. NIBRBAC000502770 from coal mine of Hongcheon on Republic of Korea by Min-Kyu Park, Yeong-Jun Park, Myung-Suk Kang, Min-Ha Kim, Soo-Young Kim, Jae-Ho Shin

    Published 2025-01-01
    “…This study sought key genes for bioremediation and agricultural applications in contaminated soils, aiding sustainable management and biotechnology. Data description We report the complete genome sequence of Pseudarthrobacter sp. …”
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  11. 4631

    Optimizing conditions to improve polyphenol content and screening antioxidant capacity with DNA protection activity of Perilla frutescens by Ngoc Thien Kim Nguyen, Huynh Anh Vu Truong, Hoang Khue Tu Nguyen

    Published 2024-06-01
    “…The study found the conditions for improving polyphenol in the extraction of P. frutescens (L.) Britt with the aid of Box-Behnken Design. This research also proposed that P. frutescens (L.) …”
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  12. 4632

    Impact of Annually Variable Dust Activity on the Recession of the Martian South Polar Seasonal Cap by Zhibin Li, Jianjun Liu, Renhao Tian, Zhaopeng Chen, Qing Zhang, Jingjing Zhang, Wei Yan, Qiang Fu, Shaoran Liu, Nannan Ma

    Published 2025-01-01
    “…This research provides observational constraints that enhance our understanding of Martian atmospheric circulation and can potentially aid the future development of polar dust activity models.…”
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  13. 4633

    Human respiratory organoids sustained reproducible propagation of human rhinovirus C and elucidation of virus-host interaction by Cun Li, Yifei Yu, Zhixin Wan, Man Chun Chiu, Jingjing Huang, Shuxin Zhang, Xiaoxin Zhu, Qiaoshuai Lan, Yanlin Deng, Ying Zhou, Wei Xue, Ming Yue, Jian-Piao Cai, Cyril Chik-Yan Yip, Kenneth Kak-Yuen Wong, Xiaojuan Liu, Yang Yu, Lin Huang, Hin Chu, Jasper Fuk-Woo Chan, Hans Clevers, Kwok Yung Yuen, Jie Zhou

    Published 2024-12-01
    “…We demonstrate that airway organoids sustain serial virus passage with the aid of CYT387-mediated immunosuppression, whereas nasal organoids that more closely simulate the upper airway achieve this without any intervention. …”
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  14. 4634

    Advances in Biomedical Missing Data Imputation: A Survey by Miriam Barrabes, Maria Perera, Victor Novelle Moriano, Xavier Giro-I-Nieto, Daniel Mas Montserrat, Alexander G. Ioannidis

    Published 2025-01-01
    “…We outline the fundamental principles underlying each imputation technique and present a detailed analysis of their advantages and disadvantages, categorized by missing data patterns. To aid practitioners in method selection, we offer practical recommendations based on critical factors such as dataset size, data type, and missingness rate. …”
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  15. 4635

    A Rare Case Presentation of Synovial Haemangioma of the Knee by Arun Karthik Ravichandran, Rajavel, Gowtham Senguttavan, Sharath Rajkumar, Saravanan Vasudevan

    Published 2025-01-01
    “…Magnetic Resonance Imaging (MRI) and arterial Doppler serve as vital diagnostic modalities that aid in the diagnosis of synovial haemangioma. Here, the authors present a case of a 15-year-old male who had experienced swelling and pain in his left knee joint for the past 13 years without receiving any prior treatment. …”
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  16. 4636

    Challenges Faced by Migrant Students in Education: A Comprehensive Analysis of Legal, Psychological, and Economic Barriers by Khasanboy Abdusamatov, Dinara Babajanova, Dilshodjon Egamberdiev, Yunus Xodjiyev, Uktamjon Tukhtaev, Nodirbek Yusupov, Sitora Shoislomova

    Published 2025-01-01
    “…Over 60% of students in the study cited issues with residency permits, affecting their eligibility for financial aid, participation in extracurricular activities, and in some cases, their ability to enroll in school at all. …”
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  17. 4637

    A comparison of sex-specific senescence patterns in a long-lived marine mammal by Kaitlin R. Macdonald, Jay J. Rotella, William A. Link

    Published 2025-01-01
    “…These results add to our understanding of sex-specific survival rates in the species and contribute information for a long-lived, polygynous species that should aid in achieving a broader understanding of aging between sexes and across the tree of life.…”
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  18. 4638

    Prognosis of patients with breast cancer who underwent breast-conserving surgery using a 3D-printed surgical guide after neoadjuvant chemotherapy by Ah Yoon Kim, Sae Byul Lee, Tae Kyung Yoo, Ji Sun Kim, Il Yong Chung, Hee Joung Kim, Jong Won Lee, Byung Ho Son, Jae Ho Jeong, Hee Jin Lee, Nam kug Kim, BeomSeok Ko

    Published 2025-01-01
    “…Between November 2015 and October 2021, patients received BCS with the aid of a 3DP-BSG. Personalized 3DP-BSG targeted tumors by tracking changes in breast and tumor anatomy on MRI before and after NACT. 203 patients with invasive breast cancer were enrolled in the study. …”
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  19. 4639

    The Role of Mathematics and Science Education in the Adult Offender Rehabilitation Process by Siphelele Mbatha, Halalisani Mngomezulu, Nonhlanhla Nduku, Onelisa Mbathu

    Published 2024-11-01
    “…The study will further aid in disseminating the unique role of offender mathematics and science education, particularly for scholars and policymakers whose focus is on offender rehabilitation in the democratic dispensation.…”
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  20. 4640

    Hydroxychloroquine and Fabry Disease: Three Case Reports Examining an Unexpected Pathologic Link and a Review of the Literature by Rouhin Sen, Kathleen Borghoff, Kirk W. Foster, Stanley J. Radio, Alan Erickson, Michelene Hearth-Holmes

    Published 2022-01-01
    “…We include key histologic features in images which aid in identifying and distinguishing hydroxychloroquine toxicity from mimickers. …”
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