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4121
The role of mNGS in the diagnosis of talaromycosis and case series
Published 2025-02-01“…All the participants presented with fever and varying respiratory symptoms, with distinct clinical characteristics aiding diagnosis. Three cases exhibited significant pulmonary infection lesions. …”
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4122
Metabolic redundancy and specialisation of novel sulfide-oxidizing Sulfurimonas and Sulfurovum along the brine-seawater interface of the Kebrit Deep
Published 2025-02-01“…In addition to the osmoprotectant pathways commonly observed in Campylobacterota, such as the synthesis and uptake of proline and glutamate, the two Kebrit Deep Sulfurovum species exhibit genomic signatures for ectoine synthesis, further aiding their adaptation to high salinity. This combination of metabolic redundancy and specialisation within the confined spatial boundaries (~1 m) of the BSI is pivotal in governing microbial interactions, including those with sulfate-reducers, heterotrophs, and other primary producers. …”
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4123
Phytocompounds from Indonesia Medicinal Herbs as Potential Apelin Receptor Agonist for Heart Failure Therapy: An In-silico Approach
Published 2025-01-01“…This study investigates bioactive phytochemicals from ten Indonesian medicinal herbs using computer-aided drug design (CADD) to predict ligand-receptor interactions via molecular docking and bioactivity prediction through machine learning. …”
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4124
An investigation of machine learning methods applied to genomic prediction in yellow-feathered broilers
Published 2025-01-01“…This work provides valuable insights into genomic prediction, aiding genetic breeding in broilers.…”
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4125
SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
Published 2025-01-01“…Our findings therefore, offer SIRT2 as a new tool to segregate GABA from H2O2 production, aiding future research in neurodegenerative diseases. …”
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4126
Partially Isolated Dual Work Function Gate IGZO TFT With Obviously Reduced Leakage Current for 3D DRAMs
Published 2024-01-01“…The relevant operation mechanism is carefully demonstrated and verified by the simulation of the electric field and potential barrier results by technical computer-aided design (TCAD). Furthermore, the impacts of the dual gate work function level, the length, and the type of isolation dielectric between dual work function gates are systematically investigated. …”
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4127
Exploring the Impact of the Multimodal CAPABLE eHealth Intervention on Health-Related Quality of Life in Patients With Melanoma Undergoing Immune-Checkpoint Inhibition: Prospective...
Published 2025-01-01“… Abstract BackgroundPatients with melanoma receiving immunotherapy with immune-checkpoint inhibitors often experience immune-related adverse events, cancer-related fatigue, and emotional distress, affecting health-related quality of life () and clinical outcome to immunotherapy. eHealth tools can aid patients with cancer in addressing issues, such as adverse events and psychosocial well-being, from various perspectives. …”
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4128
Transcriptome analysis reveals potential regulatory mechanism of genes and pathways following Aeromonas veronii infection and hypoxic stress in Chinese mitten crab, Eriocheir sinen...
Published 2025-03-01“…These findings contribute to understanding the mechanisms of stress responses in aquatic animals, potentially aiding in the development of strategies to enhance health and productivity in aquaculture.…”
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4129
AnaDetect: An extensive dataset for advancing anemia detection, diagnostic methods, and predictive analytics in healthcareMendeley Data
Published 2025-02-01“…By providing a worldwide viewpoint for comparing hematological responses, this dataset aids in the development of prediction models for the severity of anemia and patient outcomes, improving clinical decision-making. …”
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4130
High speciation in the cryptic Pristimantis celator clade (Anura: Strabomantidae) of the Mira river basin, Ecuador-Colombia
Published 2025-01-01“…Lastly, we provide a redescription of Pristimantis verecundus and species identification key to aid future research and conservation in this biogeographically influential region.…”
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4131
Thromboelastometry-Based Profiling of Haemostatic Alterations in Neonatal Sepsis by Causative Pathogens
Published 2025-01-01“…These findings provide valuable insights into the haemostatic disorders associated with sepsis, and may aid in developing an individualised approach for the treatment of those disorders, dependent on and adapted for the specific type of causative organism.…”
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4132
Prevalence and Characterization of Salmonella Species on U.S. Swine Sites as Part of the NAHMS 2021 Swine Enteric Study
Published 2025-02-01“…Salmonella species are an important cause of systemic and gastrointestinal disease in animals and humans worldwide; they are also increasingly resistant to multiple classes of antimicrobials which may aid in their treatment and control. Salmonella can also be shed asymptomatically. …”
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4133
Satisfaction and Preferences for Infusion Therapies in Advanced Parkinson’s Disease—Patient Perspective
Published 2024-12-01“…<i>Background and Objectives:</i> The rapid growth of the number of advanced Parkinson’s disease (PD) patients has caused a significant increase in the use of device-aided therapies (DATs), including levodopa–carbidopa intestinal gel (LCIG) and continuous subcutaneous apomorphine infusion (CSAI). …”
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4134
The diagnostic performance of International Ovarian Tumor Analysis: Simple Rules for diagnosing ovarian tumors—a systematic review and meta-analysis
Published 2025-01-01“…The International Ovarian Tumor Analysis Simple Rules (IOTA-SR) offers the first scoring system to aid in diagnosis. It is based on a set of five ultrasound imaging features indicative of a malignant ovarian tumor and five features indicative of a benign tumor. …”
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4135
Radiomics for Predicting the Development of Brain Edema from Normal-Appearing Early Brain-CT After Cardiac Arrest and Return of Spontaneous Circulation
Published 2025-01-01“…Radiomics analyses present a promising approach to identifying subtle imaging markers, potentially aiding early HIBI detection. <b>Methods:</b> This study retrospectively assessed post-CA patients between 2016 and 2023 who received immediate brain CTs. …”
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4136
Host factor PLAC8 is required for pancreas infection by SARS-CoV-2
Published 2025-02-01“…Results We find that analysis of circulating pancreatic enzymes aid the stratification of patients according to COVID-19 severity and predicts outcomes. …”
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4137
A Prediction Model for External Root Resorption of the Second Molars Associated With Third Molars
Published 2025-02-01“…Clinical relevance: This prediction model has the potential to aid dentists and patients in making clinical decisions regarding the necessity of M3 extraction.…”
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4138
Relationships between muscle strength, lung function, and cognitive function in Chinese middle-aged and older adults: A study based on the China health and retirement longitudinal...
Published 2025-02-01“…Understanding these relationships can provide insights into potential pathways linking these variables and may aid in better prevention of cognitive decline. Further long-term longitudinal cohort studies are needed to explore the causality between these factors.…”
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4139
Evolution paths of urban forms influenced by landforms: Asynchrony but convergence
Published 2025-01-01“…It elucidates the characteristics and evolutionary paths of urban forms based on different developmental bases, aiding in the analysis of urban expansion mechanisms. …”
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4140
Insights into the contribution of multiple factors on Ixodes ricinus abundance across Europe spanning 20 years using different machine learning algorithms
Published 2025-01-01“…We provide a summary of the factors most strongly linked to I. ricinus abundance, which can be used to guide interventions to aid the control of ticks and tick-borne disease across Europe.…”
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