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  1. 3981
  2. 3982

    Anatomic Variations Important for Dental Implantation in the Mandible—A Systematic Review by Zlata Rajkovic Pavlovic, Milos Stepovic, Marija Bubalo, Ivana Zivanovic Macuzic, Maja Vulovic, Nevena Folic, Jovana Milosavljevic, Valentina Opancina, Dobrivoje Stojadinovic

    Published 2025-01-01
    “…The results of this study can aid in choosing appropriate measurement points and give the gross picture, for clinicians, in therapy planning, considering all the landmarks of significance in the mandible.…”
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    Article
  3. 3983

    Imaging flow cytometry-based cellular screening elucidates pathophysiology in individuals with Variants of Uncertain Significance by Irena Josephina Johanna Muffels, Hans R. Waterham, Giuseppina D’Alessandro, Guido Zagnoli-Vieira, Michael Sacher, Dirk J. Lefeber, Celine Van der Vinne, Chaim M. Roifman, Koen L. I. Gassen, Holger Rehmann, Desiree Y. Van Haaften-Visser, Edward S. S. Nieuwenhuis, Stephen P. Jackson, Sabine A. Fuchs, Femke Wijk, Peter van Hasselt

    Published 2025-02-01
    “…Abstract Background Deciphering variants of uncertain significance (VUS) represents a major diagnostic challenge, partially due to the lack of easy-to-use and versatile cellular readouts that aid the interpretation of pathogenicity and pathophysiology. …”
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    Article
  4. 3984

    Risk factors for multidrug resistance in pulmonary tuberculosis patients with diabetes mellitus by Lianpeng Wu, Lianpeng Wu, Na Chen, Na Chen, Dandan Xia, Dandan Xia, Xiangao Jiang, Xiangao Jiang

    Published 2025-01-01
    “…Early identification of these risk factors can aid in the timely diagnosis and treatment of MDR-TB, potentially reducing its burden. …”
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    Article
  5. 3985

    Interventions to improve media coverage of medical research: a codesigned feasibility and acceptability study with Australian journalists by Brooke Nickel, Ray Moynihan, Alexandra Barratt, Kirsten J McCaffery, Loai Albarqouni, Tessa Copp, Thomas Dakin, Liam Mannix

    Published 2022-06-01
    “…Analysis of free-text responses identified several areas for improvement, such as including more examples to aid understanding of the counterintuitive topic of overdiagnosis and more time for discussion.Conclusions Piloting suggested the multicomponent training intervention is acceptable to journalists and provided important feedback and insights to inform a future trial of the intervention’s impact on media coverage of medicine.…”
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  6. 3986

    DepRescribing inapprOpriate Proton Pump InhibiTors (DROPIT): study protocol of a cluster-randomised controlled trial in Swiss primary care by Stefan Neuner-Jehle, Katharina Tabea Jungo, Sven Streit, Sven Trelle, Nicolas Rodondi, Carole Elodie Aubert, Kristie Rebecca Weir, Enriqueta Vallejo-Yagüe, Samantha Chan, Marie Roumet, Pascal Juillerat, Sofia Carolina Zambrano Ramos, Jennifer Inauen, Angela Edith Schulthess-Lisibach, Renata Vidonscky Lüthold, Clémentine Tombez, Martina Zangger, Flurina Jenal, Yvonne Mattmann, Christof Bieri, Michaela Barbier

    Published 2025-01-01
    “…Clusters are randomised 1:1 to either the intervention group or the control group.Interventions The intervention components consist of deprescribing tools including educational material, decision aids for both participants and GPs, and additional trainings for GPs only. …”
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    Article
  7. 3987

    Immune Dysfunction and Coinfection with Human Immunodeficiency Virus and Schistosoma japonicum in Yi People by Yu Yang, Peng-Lei Xiao, Ya Yang, Jian-Chuan Gao, Yan Shi, Wan-Ting Cheng, Yue Chen, Xiu-Xia Song, Qing-Wu Jiang, Yi-Biao Zhou

    Published 2018-01-01
    “…A block design study was conducted in a Yi county in southwestern China, one of the endemic areas of both HIV/AIDS and S. japonicum in China. All participants were screened for HIV antibodies and S. japonicum antibodies (SjAb) and were classified into four groups: HIV(+)/S. japonicum(−), HIV(−)/S. japonicum (+), HIV(+)/S. japonicum(+), and HIV(−)/S. japonicum(−). …”
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  8. 3988

    Comparison of glycosylated fibronectin versus soluble fms-like tyrosine kinase/placental growth factor ratio testing for the assessment of pre-eclampsia: protocol for a multicentre... by Marcus Green, Chao Wang, Sarah Fisher, Amarnath Bhide, Ramesh Ganapathy, Basky Thilaganathan, Nouran Elbarbary

    Published 2025-02-01
    “…Glycosylated fibronectin (GlyFn) level for the prediction of pre-eclampsia development is available as a POC test (Lumella) and has the potential to aid rapid clinical decision making. This study aimed to test the hypothesis that the sensitivity of the GlyFn test is not inferior to that of the current gold standard of soluble fms-like tyrosine kinase (sFlt)/PlGF-based laboratory testing for pre-eclampsia.Methods and analysis This is a multicentre prospective study. …”
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  9. 3989

    Online tools to predict individualised survival for primary oesophageal cancer patients with and without pathological complete response after neoadjuvant therapy followed by oesoph... by Jie Zhang, Xiang Chen, Dong Dong, Lijie Tan, Yajie Zhang, Hecheng Li, Yuqin Cao, Binhao Huang, Han Tang, Tianzheng Shen, Xijia Feng, Jiahao Zhang, Liqiang Shi, Chengqiang Li, Heng Jiao

    Published 2024-07-01
    “…The predictive models for pCR and non-pCR patients demonstrated good calibration and clinical utility, with acceptable discrimination that surpassed that of the current tumour, node, metastases staging system.Conclusions The web-based dynamic nomograms for pCR (https://predict-survival.shinyapps.io/pCR-eso/) and non-pCR patients (https://predict-survival.shinyapps.io/non-pCR-eso/) developed in this study can facilitate the calculation of OS probability for individual patients undergoing neoadjuvant therapy and radical oesophagectomy, aiding clinicians and patients in making personalised treatment decisions.…”
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  10. 3990

    The Clinical Pharmacokinetics and Pharmacodynamics of Glimepiride—A Systematic Review and Meta-Analysis by Mubara Azhar, Mohammed S. Alasmari, Ammara Zamir, Hamid Saeed, Faleh Alqahtani, Tanveer Ahmad, Muhammad Fawad Rasool

    Published 2025-01-01
    “…<b>Conclusions:</b> The findings of this review would be helpful in the development and evaluation of PK models that may aid in suggesting individualized dosing.…”
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    Article
  11. 3991

    Association between Corrected QT Interval, QT Dispersion and Clinico-biochemical Severity of Diabetic Ketoacidosis in Children Aged 1-12 Years: A Prospective Cohort Study by Hamritha Ashokkumar, A Suriya, Shreenivas RachakondaPoovazhagi, Shreenivas Rachakonda, Shreenivas Rachakonda

    Published 2025-01-01
    “…Routine ECG monitoring is essential for the early detection of QT prolongation, aiding in the prevention of life-threatening arrhythmias and improving patient outcomes.…”
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    Article
  12. 3992

    Seed Protein Content Estimation with Bench-Top Hyperspectral Imaging and Attentive Convolutional Neural Network Models by Imran Said, Vasit Sagan, Kyle T. Peterson, Haireti Alifu, Abuduwanli Maiwulanjiang, Abby Stylianou, Omar Al Akkad, Supria Sarkar, Noor Al Shakarji

    Published 2025-01-01
    “…To fully utilize the spectral and texture features of the full VNIR and SWIR spectral domains, a computer-vision-aided image co-registration methodology was implemented to seamlessly align the VNIR and SWIR bands. …”
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  13. 3993
  14. 3994

    Injury characteristics, mechanisms, and game circumstances in junior community-level Australian football by Indianna L. Franke, Andrea B. Mosler, Brooke E. Patterson, Kay M. Crossley, Patrick Clifton, Steven McPhail, Mark J. Scholes, Matthew G. King

    Published 2025-06-01
    “…Methods: All community junior Australian football players from one Victorian-based league were eligible to participate if they were injured during a game and presented to the gameday first aid medics. Injured players were subsequently followed up with a phone call to undertake an injury surveillance survey. …”
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  15. 3995

    Using Passive BCI for Personalization of Assistive Wearable Devices: A Proof-of-Concept Study by Asghar Mahmoudi, Morteza Khosrotabar, Klaus Gramann, Stephan Rinderknecht, Maziar A. Sharbafi

    Published 2025-01-01
    “…Assistive wearable devices can significantly enhance the quality of life for individuals with movement impairments, aid the rehabilitation process, and augment movement abilities of healthy users. …”
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    Article
  16. 3996

    PolyRes-Net: A Polyhierarchical Residual Network for Decoding Anatomical Complexity in Medical Image Segmentation by Amr Magdy, Khalid N. Ismail, Marghny H. Mohamed, Mahmoud Hassaballah, Haitham Mahmoud, Mohammed M. Abdelsamea

    Published 2025-01-01
    “…Furthermore, each decoder step is preceded by an attention gate, aiding in the extraction of the most salient features from the preceding layer, while skip connections correspond to the respective encoder steps. …”
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  17. 3997

    Automatic GPR detection of grouting defects behind the tunnel shield segments based on wavelet coherence analysis combined with modified Res-RCNN by Dengyi Wang, Ming Peng, Liu Liu, Xiongyao Xie, Zhenming Shi, Yaoying Liang, Jian Shen, Qiyu Wu

    Published 2025-07-01
    “…The proposed methods are verified through full-size model tests with the aid of synthetic experiments to quantify their performance. …”
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    Article
  18. 3998

    New prognostic model in patients with advanced urothelial carcinoma treated with second-line immune checkpoint inhibitors by Ernest Choy, Yohann Loriot, Fabio Calabrò, Cora N Sternberg, Guillermo De Velasco, Daniel Castellano, Roubini Zakopoulou, Aristotelis Bamias, Nicholas James, Axel Merseburger, F Lopez-Rios, Mario Kramer, Kimon Tzannis

    Published 2023-01-01
    “…This model represents an improvement over the Bellmunt algorithm and could aid selection of patients with aUC for second-line immunotherapy.Trial registration number NCT02928406.…”
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    Article
  19. 3999

    The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

    Published 2025-02-01
    “…These nanovesicles, with their distinct physical properties and ability to penetrate target cells, may prove beneficial in conditions involving the depletion of M2 macrophages and M1 macrophage-induced diseases, potentially aiding in the reduction of inflammation and tissue injury.…”
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    Article
  20. 4000

    Genetic Mapping for Seed Aging Tolerance Under Multiple Environments in Sweet Corn by Yanchao Du, Jianting Lin, Haoxuan Jiang, Huating Zhao, Xuebiao Zhang, Ruigang Wang, Faqiang Feng

    Published 2025-01-01
    “…Enhancing seed vigor is a pivotal goal in sweet corn breeding, as improved seed sowing quality is crucial for agricultural development, aiding in better resilience against storage adversities and facilitating long-term germplasm preservation. …”
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    Article